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SURFACES IN 4-DIMENSIONAL SPHERE
Yamada, Akira Korean Mathematical Society 1996 대한수학회지 Vol.33 No.1
Met $\tilde{M} = (\tilde{M}, \tilde{J}, <>)$ be an almost Hermitian manifold and M a submanifold of $\tilde{M}$. According to the behavior of the tangent bundle TM with respect to the action of $\tilde{J}$, we have two typical classes of submanifolds. One of them is the class of almost complex submanifolds and another is the class of totally real submanifolds. In 1990, B. Y. Chen [4], [5] introduced the concept of the class of slant submanifolds which involve the above two classes. He used the Wirtinger angle to measure the behavior of TM with respect to the action of $\tilde{J}$.
Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies
Akira Nakajima,Kiyofumi Yamada,Yasushi OHIZUMI 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.2
Alzheimer’s disease (AD), the most common form of dementia among the elderly, is characterized by the progressive declineof cognitive function and has a detrimental impact worldwide. Despite intensive laboratory and clinical research over the lastthree decades, pharmacological options for the prevention and effective long-term treatment of AD are not currently available. Consequently, successful therapeutic and preventive treatments for AD are needed. When researching materials from naturalresources having anti-dementia drug activity, we identified nobiletin, a polymethoxylated flavone from the peel of Citrus depressa. Nobiletin exhibited memory-improving effects in various animal models of dementia and exerted a wide range of beneficial effectsagainst pathological features of AD including amyloid-β (Aβ) pathology, tau hyperphosphorylation, oxidative stress, cholinergicneurodegeneration and dysfunction of synaptic plasticity-related signaling, suggesting this natural compound could become anovel drug for the treatment and prevention of AD.
Akira Iwata,Kuniyoshi Abumi,Masahiko Takahata,Hideki Sudo,Katsuhisa Yamada,Tsutomu Endo,Norimasa Iwasaki 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.2
Study Design: Retrospective case-control study, level 4. Purpose: To clarify the risk factors for late subaxial lesion after occipitocervical (O-C) reconstruction. We examined cases requiring fusion-segment-extended (FE) reconstruction in addition to/after O-C reconstruction. Overview of Literature: Patients with rheumatoid arthritis (RA) frequently require O-C reconstruction surgery for cranio-cervical lesions. Acceptable outcomes are achieved via indirect decompression using cervical pedicle screws and occipital plate–rod systems. However, late subaxial lesions may develop occasionally following O-C reconstruction. Methods: O-C reconstruction using cervical pedicle screws and occipital plate–rod systems was performed between 1994 and 2007 in 113 patients with RA. Occipito-atlanto-axial (O-C2) reconstruction was performed for 89 patients, and occipito-subaxial cervical (O-under C2) reconstruction was performed for 24 patients. We reviewed the cases of patients requiring FE reconstruction (fusion extended group, FEG) and 26 consecutive patients who did not require FE reconstruction after a follow-up of >5 years (non-fusion extended group, NEG) as controls. Results: FE reconstructions were performed for nine patients at an average of 45 months (range, 24–180 months) after O-C reconstruction. Of the 89 patients, three (3%) underwent FE reconstruction in cases of O-C2 reconstruction. Of the 24 patients, five (21%) underwent FE reconstruction in cases of O-under C2 reconstruction (p =0.003, Fisher exact test). Age, sex, RA type, and neurological impairment stage were not significantly different between FEG and NEG. O-under C2 reconstruction, larger correction angle (4° per number of unfixed segment), and O-C7 angle change after O-C reconstruction were the risk factors for late subaxial lesions on radiographic assessment. Conclusions: Overcorrection of angle at fusion segments requiring O-C7 angle change was a risk factor for late subaxial lesion in patients with RA with fragile bones and joints. Correction should be limited, considering the residual mobility of the cervical unfixed segments.
( Eiji Yamada ),( Hidenori Ohkubo ),( Takuma Higurashi ),( Eiji Sakai ),( Hiroki Endo ),( Hirokazu Takahashi ),( Eri Uchida ),( Emi Tanida ),( Nobuyoshi Izumi ),( Akira Kanesaki ),( Yasuo Hata ),( Tet The Editorial Office of Gut and Liver 2013 Gut and Liver Vol.7 No.5
Background/Aims: Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to obesity and conducted a study of the features and risk factors for this disorder in Japan. Methods: Right-sided di-verticulitis and left-sided diverticulitis patients (total of 215) were compared with respect to background, particularly obesity-related factors to identify risk factors for diverticulitis. Results: There were 166 (77.2%) right-sided diverticulitis patients and 49 (22.8%) left-sided diverticulitis patients. The proportions of obese patients (body mass index ≥25 kg/m2, p=0.0349), viscerally obese patients (visceral fat area ≥100 cm2, p=0.0019), patients of mean age (p=0.0003), and el-derly patients (age ≥65 years, p=0.0177) were significantly higher in the left-sided-diverticulitis group than in the right-sided-diverticulitis group. The proportion of viscerally obese patients was significantly higher in the left-sided-diverticulitis group than in the left-sided-diverticulosis group (p=0.0390). Conclusions: This study showed that obesity, particularly visceral obesity, was a risk factor for left-sided diverticulitis in Japan. (Gut Liver 2013;7:532-538)
A Study on Aspects of Attrition Wear of Cutting Grains in Grinding Process
Keiji Yamada,Takashi Ueda,Akira Hosokawa 한국정밀공학회 2011 International Journal of Precision Engineering and Vol. No.
In this study, the influences caused by the wear of grinding wheel are investigated experimentally. The infrared radiation pyrometer with an optical fiber is developed and applied for the temperature measurement in the surface grinding process of carbon steels. Experimental data such as the temperature, the number and the size of effective cutting grains and the grinding forces are obtained over the wheel life, and they are used for the calculation of the thermal energy fraction to the workpiece, the grinding wheel and the chips. Thermal damage begins to be caused on the ground surface, as the attrition wear of grains decreases the number of effective cutting grains and degrades the efficiency of grinding wheel. The measuring of radiation pulses from the cutting grains makes it possible to detect the degradation of grinding wheel at an early stage of wheel life and prevent the severe damages on work surface.