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Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea
Williams S. Ebhota,Tien-Chien Jen 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.7 No.1
The rise in global urbanization comes with sustainable development challenges, especially in lower-middle-income countries. In response to these urbanization and energy challenges, this study focuses on the roles of energy materials (EMs) advances on community-scale hybrid renewable energy systems (HRES). The study proposes the integration of energy material (EM) R&D into HRES (EMR&D-HRES). The study examines the economic benefits and the environmental and health consequences that trail the deployment of fossil fuels. Special attention was given to SSA, a region that—accommodates the highest population without modern energy; emits the least CO2 to the global CO2 emissions and yet endangered by climate change challenges and air pollution diseases. The study includes global responses to energy challenges, such as increase alternative energies share, with special attention to solar photovoltaic (PV) power generation technologies; policy framework; HRES and effects of PV materials advances on HRES. This study is of the view that a further breakthrough in the production of low-cost flexible thin film PV modules will facilitate energy trilemma accomplishment. The exploitation of the attributes of atomic layer deposition in manufacturing of thin film is seen as a potential future production technique, suitable for efficient flexible thin-film PV module production.
( Williams Agyei Appiah ),박주남,변승우,유명현,이용민 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.0
To meet the various application requirements of LIBs, the energy and power density of LIBs needs to be optimized for a given electrode material by controlling its porosity and thickness. Changes in electrode thickness and porosity affect the electrochemical performance of LIBs. Hence we employ a mathematical model to study and optimize the electrochemical performance of graphite/LiNi<sub>0.6</sub>Co<sub>0.2</sub>Mn<sub>0.2</sub>O<sub>2</sub> cells with different cathode thicknesses and porosities. A non-linear least square method is used to provide a better understanding of the different porosities and thicknesses on Li-ion transport in both liquid and solid phases. Ragone plots are generated for the various cell designs where the specific energy and average specific power are evaluated. The cells are optimized for discharge times ranging from 10 h to 2 min in order to map the maximum performance of this chemistry under wide operating range.
An experimental and numerical approach in strength prediction of reclaimed rubber concrete
Williams, Kanmalai C.,Partheeban, P. Techno-Press 2018 Advances in concrete construction Vol.6 No.1
Utilization of waste tires may be considered as one of the solution to the problems faced by the local authorities in disposing them. Reclaimed rubber (RR) is being used in concrete for replacing conventional aggregates. This research work is focused on the strength prediction of reclaimed rubber concrete using a Genetic Algorithm (GA) for M40 grade of concrete and comparing it with experimental results. 1000 sets were taken and 100 iterations were run during training of GA models. A base study has been carried out in this research work partially replacing cement with three types of fillers such as Plaster of Paris (POP), Fly Ash (FA) and Silica Fume (SF). A total of 243 cubes were cast and tested for compression using a Universal Testing Machine. It was found that SF produced maximum strength in concrete and was used in the main study with reclaimed rubber. Tests were conducted on 81 cube samples with a combination of optimum SF percent and various proportions of RR replacing coarse aggregates in concrete mix. Compressive strength tests of concrete at 7, 14 and 28 days reveal that the maximum strength is obtained at 12 percent replacement of cement and 9 percent replacement of coarse aggregates respectively. Moreover the GA results were found to be in line with the experimental results obtained.
Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression
Williams, Adam,Lee, Gap Ryol,Spilianakis, Charalampos G.,Hwang, Soo Seok,Eisenbarth, Stephanie C.,Flavell, Richard A. National Academy of Sciences 2013 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.110 No.17
<P>The T helper type 2 (Th2) cytokine genes <I>Il4</I>, <I>Il5</I>, and <I>Il13</I> are contained within a 140-kb region of mouse chromosome 11 and their expression is controlled by a locus control region (LCR) embedded within this locus. The LCR is composed of a number of DNase I–hypersensitive sites (HSs), which are believed to encompass the regulatory core of the LCR. To determine the function of these sites, mutant mice were generated in which combinations of these HSs had been deleted from the endogenous LCR, and the effect on Th2 cytokine expression was assessed through the use of in vivo and in vitro models. These experiments revealed that, although all of the hypersensitive sites analyzed are important for appropriate LCR function, some sites are more important than others in regulating cytokine expression. Interestingly, each LCR mutation showed contrasting effects on cytokine expression, in some cases with mutants displaying opposing phenotypes between in vitro cultures and in vivo immunizations. These studies indicated that Rad50 hypersensitive site 6 was the singularly most important HS for Th2 cytokine expression, displaying consistent reductions in cytokine levels in all models tested. Furthermore analysis of chromatin modifications revealed that deletion of Rad50 hypersensitive site 6 impacted epigenetic modifications at the promoters of the <I>Il4</I>, <I>Il5</I>, and <I>Il13</I> genes as well as other regulatory sites within the Th2 locus.</P>
2P-393 Computational analysis of capacity fade in spinel-based cathode and artificial graphite anode
( Williams Agyei Appiah ),박주남,변승우,유명현,이용민 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1
A comprehensive mathematical model is developed to study the cycling performance of LiMn2O4/graphite lithium ion cells. The proposed model takes into consideration the formation and dissolution of the solid electrolyte interphase (SEI) at the anode, Mn(II) dissolution of LiMn2O4 cathode active material due to Mn(III) disproportionation reaction and its effects on the SEI at the anode as well as the formation of cathode electrolyte interphase (CEI) on the cathode. The developed model is incorporated into the Newman’s Porous Composite Electrode framework (PCE) and implemented in the battery module of COMSOL Multiphysics. The proposed model is used to study the effects of variations in temperature and voltage range of cycling on the capacity fade and changes in volume fraction of cathode active material, resistance in the cell and SEI thickness.
Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor
Williams, Simon J.,Sohn, Kee Hoon,Wan, Li,Bernoux, Maud,Sarris, Panagiotis F.,Segonzac, Cecile,Ve, Thomas,Ma, Yan,Saucet, Simon B.,Ericsson, Daniel J.,Casey, Lachlan W.,Lonhienne, Thierry,Winzor, Dona American Association for the Advancement of Scienc 2014 Science Vol.344 No.6181
<P><B>Universal Immune Function</B></P><P>Certain pathogen effectors are detected in plants by cytoplasmic receptors. First solving the crystal structures of <I>Arabidopsis</I> receptors, <B>Williams <I>et al.</I></B> (p. 299; see the Perspective by <B>Nishimura and Dangl</B>) discovered that in the resting state, the structures form a heterodimer that readies the complex for effector binding and keeps the signaling domains from firing too early. Once the pathogen effector binds, the structure of the complex shifts such that the signaling domains can form a homodimer to initiate downstream signaling. Similarities between these plant-pathogen receptors and Toll-like receptors in animals suggest the molecular mechanisms may translate broadly.</P>
Commitment to Sport and Exercise: Re-examining the Literature for a Practical and Parsimonious Model
Williams, Lavon The Korean Society for Preventive Medicine 2013 Journal of Preventive Medicine and Public Health Vol.46 No.suppl
A commitment to physical activity is necessary for personal health, and is a primary goal of physical activity practitioners. Effective practitioners rely on theory and research as a guide to best practices. Thus, sound theory, which is both practical and parsimonious, is a key to effective practice. The purpose of this paper is to review the literature in search of such a theory - one that applies to and explains commitment to physical activity in the form of sport and exercise for youths and adults. The Sport Commitment Model has been commonly used to study commitment to sport and has more recently been applied to the exercise context. In this paper, research using the Sport Commitment Model is reviewed relative to its utility in both the sport and exercise contexts. Through this process, the relevance of the Investment Model for study of physical activity commitment emerged, and a more parsimonious framework for studying of commitment to physical activity is suggested. Lastly, links between the models of commitment and individuals' participation motives in physical activity are suggested and practical implications forwarded.