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RISS 인기검색어
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- 저자 : Wenrui Duan (검색결과 3 건)
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Multidisciplinary optimization of etch process chamber on the basis of MCDM
Wenrui Duan,Ling Tian,Zhansong Wang,Wenbin Han 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.11
A multidisciplinary optimization integrating flow and plasma performance was used to develop an etch process chamber with dualfrequencycapacitively coupled plasma. Pressure and ion density characteristics are significantly influenced by structures, such as electrodegap, number of confinement rings, electrode radius, and process conditions of flow rate. This study aims to minimize the objectivefunctions of pressure and ion density simultaneously. Based on flow and plasma simulation, an approximation model is created usingquartic response surface method (RSM). A genetic algorithm was utilized to explore Pareto front. The concept of entropy weight is combinedwith the weight defined in analytic hierarchy process to create a synthetic weight over the objectives. The non-dominated solutionsare ranked by the modified technique for order preference by similarity to ideal solution. The ranking list helps arrive at rational decisionsand provide a unique solution. The optimum structure of the chamber is obtained and the final solution is discussed. The proposed optimizationframework improves the distribution profile of pressure and ion density.
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Effects of sheep slaughter age on myogenic characteristics in skeletal muscle satellite cells
Han Yunfei,Guo Wenrui,Su Rina,Zhang Yanni,Yang Le,Borjigin Gerelt,Duan Yan 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.4
Objective: The objective of this study was to investigate the effects of sheep slaughter age on myogenic characteristics in skeletal muscle satellite cells (SMSCs).Methods: Primary SMSCs were isolated from hind leg biceps femoris muscles of Wurank lambs (slaughtered at three months, Mth-3) and adults (slaughtered at fifteen months, Mth-15). SMSCs were selected by morphological observation and fluorescence staining. Myogenic regulatory factors (MRF) and myosin heavy chain (MyHC) expressions of SMSCs were analyzed on days 1, 3, 4, and 5.Results: The expressions of myogenic factor 5 (Myf5), myogenic differentiation (MyoD), Myf6, and myogenin (MyoG) in Mth-15 were significantly higher in Mth-15 than in Mth-3 on days 1, 3, and 4 (p<0.05). However, MyoG expression in Mth-15 was significantly lower than in Mth-3 on day 5 (p<0.05). The expressions of MyHC I, MyHC IIa, and MyHC IIx in Mth-15 were significantly higher than in Mth-3 on days 1 and 3 (p<0.05), and MyHC IIb were significantly lower than in Mth-3 on days 3 and 4 (p<0.05). In contrast, the expression of MyHC IIx in Mth-15 was significantly lower and MyHC IIb was significantly higher than in Mth-3 on days 5 (p<0.05).Conclusion: The slaughter age altered the expression of MRFs and MyHCs in SMSCs while differentiation, which caused the variation of myogenic characteristics, and thus may affect the meat quality of Wurank sheep. Objective: The objective of this study was to investigate the effects of sheep slaughter age on myogenic characteristics in skeletal muscle satellite cells (SMSCs). Methods: Primary SMSCs were isolated from hind leg biceps femoris muscles of Wurank lambs (slaughtered at three months, Mth-3) and adults (slaughtered at fifteen months, Mth-15). SMSCs were selected by morphological observation and fluorescence staining. Myogenic regulatory factors (MRF) and myosin heavy chain (MyHC) expressions of SMSCs were analyzed on days 1, 3, 4, and 5. Results: The expressions of myogenic factor 5 (Myf5), myogenic differentiation (MyoD), Myf6, and myogenin (MyoG) in Mth-15 were significantly higher in Mth-15 than in Mth-3 on days 1, 3, and 4 (p<0.05). However, MyoG expression in Mth-15 was significantly lower than in Mth-3 on day 5 (p<0.05). The expressions of MyHC I, MyHC IIa, and MyHC IIx in Mth-15 were significantly higher than in Mth-3 on days 1 and 3 (p<0.05), and MyHC IIb were significantly lower than in Mth-3 on days 3 and 4 (p<0.05). In contrast, the expression of MyHC IIx in Mth-15 was significantly lower and MyHC IIb was significantly higher than in Mth-3 on days 5 (p<0.05). Conclusion: The slaughter age altered the expression of MRFs and MyHCs in SMSCs while differentiation, which caused the variation of myogenic characteristics, and thus may affect the meat quality of Wurank sheep.
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The Antiobesity Effects and Potential Mechanisms of Theaflavins
Jinghua Peng,Jing Hu,Yi Fang,Jun Wang,Yu Cao,Wenrui Liu,Lianxiang Duan 한국식품영양과학회 2024 Journal of medicinal food Vol.27 No.1
Theaflavins are the characteristic polyphenols in black tea which can be enzymatically synthesized. In thisreview, the effects and molecular mechanisms of theaflavins on obesity and its comorbidities, including dyslipidemia, insulinresistance, hepatic steatosis, and atherosclerosis, were summarized. Theaflavins ameliorate obesity potentially via reducingfood intake, inhibiting pancreatic lipase to reduce lipid absorption, activating the adenosine monophosphate-activated proteinkinase (AMPK), and regulating the gut microbiota. As to the comorbidities, theaflavins ameliorate hypercholesterolemia byinhibiting micelle formation to reduce cholesterol absorption. Theaflavins improve insulin sensitivity by increasing thesignaling of protein kinase B, eliminating glucose toxicity, and inhibiting inflammation. Theaflavins ameliorate hepaticsteatosis via activating AMPK. Theaflavins reduce atherosclerosis by upregulating nuclear factor erythropoietin-2-relatedfactor 2 signaling and inhibiting plasminogen activator inhibitor 1. In randomized controlled trails, black tea extractscontaining theaflavins reduced body weight in overweight people and improved glucose tolerance in healthy adults. Theamelioration on the hyperlipidemia and the prevention of coronary artery disease by black tea extracts were supportedby meta-analysis.
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