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Employing rotating vaneless diffuser to enhance the performance of plenum fan
Dou, Hua-Shu,Wu, Lin,Wei, Yikun,Chen, Yongning,Cao, Wenbin,Ying, Cunlie Korean Society for Fluid machinery 2017 International journal of fluid machinery and syste Vol.10 No.1
Numerical simulation is carried out for flow characteristics in a plenum fan and the influence of the diameter ratio of the rotating vaneless diffuser on the performance of plenum fan is analyzed. The diameter ratio of the rotating vaneless diffuser employed is from 1.03 to 1.3. The research results show that the rotating vaneless diffuser is able to enhance the performance of plenum fan. It is found that there is significant improvement in static pressure and efficiency at the diameter ratio of 1.05 at high flow coefficients, while the optimal diameter ratio is 1.2 at rated and low flow coefficient.
Design and simulation of self-organizing network routing algorithm based on Q-learning
Yuejia Dou,Huilin Liu,Liangkang Wei,Shiyou Chen 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09
With the continuous advancement of computer network communication technology, traditional wired and wireless networks are limited by cables and base stations, and are not applicable in some application scenarios. Therefore, mobile wireless communication methods have attracted more and more attention. Due to its dynamic topology and self-organizing without center, the self-organizing network can form a mobile temporary multi-hop mobile communication network through multiple wireless communication devices, which can well meet the above requirements. At present, research on self-organizing networks mainly focuses on routing protocols. The main types are based on network topology information and location information. This paper designs a routing algorithm based on link reliability. The algorithm fully considers the self-organizing network link information, and models the node"s sending and receiving work as a Markov decision process, and uses Q-learning to demodulate. This article used NS2 for network simulation and analysis and comparison of performance indicators with traditional routing algorithms.
Trichoderma biodiversity in major ecological systems of China
Kai Dou,Jinxin Gao,Chulong Zhang,Hetong Yang,Xiliang Jiang,Jishun Li,Yaqian Li,Wei Wang,Hongquan Xian,Shigui Li,Yan Liu,Jindong Hu,Jie Chen 한국미생물학회 2019 The journal of microbiology Vol.57 No.8
An investigation of Trichoderma biodiversity involving a large-scale environmental gradient was conducted to understand the Trichoderma distribution in China. A total of 3,999 isolates were isolated from forestry, grassland, wetland and agriculture ecosystems, and 50 species were identified based on morphological characteristics and sequence analysis of genetic markers. Trichoderma harzianum showed the largest proportion of isolates and the most extensive distribution. Hypocrea semiorbis, T. epimyces, T. konilangbra, T. piluliferum, T. pleurotum, T. pubescens, T. strictipilis, T. hunua, T. oblongisporum and an unidentified species, Trichoderma sp. MA 3642, were first reported in China. Most Trichoderma species were distributed in Jilin and Heilongjiang Provinces in northeast China and the fewest were distributed in Qinghai Province. Based on the division of ecological and geographic factors, forestry ecosystems and low-altitude regions have the greatest species biodiversity of Trichoderma.
Closed Walk Ferry Route Design for Wireless Sensor Networks
( Qiang Dou ),( Yong Wang ),( Wei Peng ),( Zhenghu Gong ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.10
Message ferry is a controllable mobile node with large capacity and rechargeable energy to collect information from the sensors to the sink in wireless sensor networks. In the existing works, route of the message ferry is often designed from the solutions of the Traveling Salesman Problem (TSP) and its variants. In such solutions, the ferry route is often a simple cycle, which starts from the sink, access all the sensors exactly once and moves back to the sink. In this paper, we consider a different case, where the ferry route is a closed walk that contains more than one simple cycle. This problem is defined as the Closed Walk Ferry Route Design (CWFRD) problem in this paper, which is an optimization problem aiming to minimize the average weighted delay. The CWFRD problem is proved to be NP-hard, and the Integer Linear Programming (ILP) formulation is given. Furthermore, a heuristic scheme, namely the Initialization-Split-Optimization (ISO) scheme is proposed to construct closed walk routes for the ferry. The experimental results show that the ISO algorithm proposed in this paper can effectively reduce the average weighted delay compared to the existing simple cycle based scheme.
Employing rotating vaneless diffuser to enhance the performance of plenum fan
Hua-Shu Dou,Lin Wu,Yikun Wei,Yongning Chen,Wenbin Cao,Cunlie Ying 한국유체기계학회 2017 International journal of fluid machinery and syste Vol.10 No.1
Numerical simulation is carried out for flow characteristics in a plenum fan and the influence of the diameter ratio of the rotating vaneless diffuser on the performance of plenum fan is analyzed. The diameter ratio of the rotating vaneless diffuser employed is from 1.03 to 1.3. The research results show that the rotating vaneless diffuser is able to enhance the performance of plenum fan. It is found that there is significant improvement in static pressure and efficiency at the diameter ratio of 1.05 at high flow coefficients, while the optimal diameter ratio is 1.2 at rated and low flow coefficient.
Stationary Distribution for the Mobilities in Catastrophe Rescue Scenario
( Yong Wang ),( Wei Peng ),( Qiang Dou ),( Zhenghu Gong ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.2
Mobility Model has drawn more and more attentions since its critical role in Mobile Wireless Networks performance evaluation. This paper analyzes the mobility patterns in the catastrophe rescue scenario, and proposes the Random Waypoint with Base Point mobility model to model these characteristics. We mathematically analyze the speed and spatial stationary distributions of the nodes and derive explicit expressions for the one dimensional case. In order to keep the stationary distribution through the entire simulation procedure, we provide strategies to initialize the speed, location and destination of the nodes at the beginning of the simulation. The simulation results verify the derivations and the proposed methods in this paper. This work gives a deep understanding of the properties of the Random Waypoint with Base Point mobility model and such understanding is necessary to avoid misinterpretation of the simulation results. The conclusions are of practical value for performance analysis of mobile wireless networks, especially for the catastrophe rescue scenario.
Fei Xiaowei,Dou Ya-nan,Sun Kai,Wei Jialiang,Guo Qingdong,Wang Li,Wu Xiuquan,Lv Weihao,Jiang Xiaofan,Fei Zhou 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
The tripartite motif (TRIM) 22 and mitogen-activated protein kinase (MAPK) signaling pathways play critical roles in the growth of glioblastoma (GBM). However, the molecular mechanism underlying the relationship between TRIM22 and MAPK signaling remains unclear. Here, we found that TRIM22 binds to exon 2 of the sphingosine kinase 2 (SPHK2) gene. An ERK1/2-driven luciferase reporter construct identified TRIM22 as a potential activator of MAPK signaling. Knockout and overexpression of TRIM22 regulate the inhibition and activation of MAPK signaling through the RING-finger domain. TRIM22 binds to Raf-1, a negative regulator of MAPK signaling, and accelerates its degradation by inducing K48-linked ubiquitination, which is related to the CC and SPRY domains of TRIM22 and the C1D domain of Raf-1. In vitro and in vivo, an SPHK2 inhibitor (K145), an ERK1/2 inhibitor (selumetinib), and the nonphosphorylated mutant Raf-1S338A inhibited GBM growth. In addition, deletion of the RING domain and the nuclear localization sequence of TRIM22 significantly inhibited TRIM22-induced proliferation of GBM cells in vivo and in vitro. In conclusion, our study showed that TRIM22 regulates SPHK2 transcription and activates MAPK signaling through posttranslational modification of two critical regulators of MAPK signaling in GBM cells.
Bo Li,Wei Kang,Hanhan Liu,Yanrong Wang,Changzhong Yu,Xinyi Zhu,Jie Dou,Haibo Cai,Changlin Zhou 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.7
Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as one of the most important pathogens both in health care and in community-onset infections. Cbf-K16, a cathelicidin-like antimicrobial peptide, presented broad antimicrobial activity during our previous studies. We evaluated the potential for synergy of Cbf-K16 with ceftazidime/ampicilin against MRSA, which was resistant to these two antibiotics with the minimum inhibitory concentration more than 64 μg/ml. The combinations showed a synergistic effect by a checkerboard assay with a fractional inhibitory concentration index ≤0.5. The killing curves of the combination treatment against MRSA showed that CFU counts decreased rapidly within 4 h by almost five logs, while single medication groups and the control group exhibited little inhibitory effect. In addition, in a mice bacteremia model, studies indicated that the combination treatment significantly prolonged the survival time of mice infected with MRSA, with a death protection rate of 80 %. Flow cytometry analysis and transmission electron microscopy indicated that combination- treated MRSA was completely ruptured with the cellular contents leaked out. The synergistic effect showed that Cbf-K16 selectively killed cells with non-integrity induced by cell wall inhibition antibiotics, suggesting that Cbf-K16 is a potential therapeutic agent and adjuvant for antimicrobial chemotherapy.
Optimization of Blade Profile of a Plenum Fan
Wu, Lin,Dou, Hua-Shu,Wei, Yikun,Chen, Yongning,Cao, Wenbin,Ying, Cunlie Korean Society for Fluid machinery 2016 International journal of fluid machinery and syste Vol.9 No.1
A method of optimization design for the blade profile of a centrifugal impeller by controlling velocity distribution is presented, and a plenum fan is successfully designed. This method is based on the inner flow calculation inside the centrifugal impeller, and is related to the distribution of relative velocity. The results show that after optimization, the boundary layer separation on the suction surface has been inhibited and the stability of plenum fan is improved. The flow at the impeller outlet is also studied, and the jet-wake pattern at the impeller outlet is improved obviously by optimization. The calculation result shows that the static pressure and static pressure efficiency can be increased by 15.4% and 21.4% respectively.