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      • KCI등재

        3D Dynamic Image Modeling Based on Machine Learning in Film and Television Animation

        Yuwei Wang 한국멀티미디어학회 2023 The journal of multimedia information system Vol.10 No.1

        With the deep integration and rapid development of computer technology and film and television animation in recent years, computer anima-tion technology has gradually created objective practical value. 3D animation technology also plays a key role in film and television special effects and advertising special effects. As a new type of multimedia data, human motion capture data can be used for 3D human model model-ing and human motion simulation because of its high fidelity. A human motion pattern recognition method based on long short-term memory network (LSTM) is proposed. The model uses a deep learning neural network composed of a 2-layer LSTM network to automatically extract features from the collected human body feature information. Then, the multi-class motion patterns are modeled in time series to quickly identify different motion patterns in real time. To evaluate the performance of this model, the effectiveness of this method in identifying six different motion modes is validated using an open dataset. At the same time, this method is compared with four methods based on in-depth learning model. Experimental results verify the effectiveness of the method. It provides a feasible method for human motion recognition and modeling based on capture data in video animation.

      • SCIESCOPUSKCI등재

        BF-30 effectively inhibits ciprofloxacin-resistant bacteria in vitro and in a rat model of vaginosis

        Wang, Jing,Li, Bing,Li, Yang,Dou, Jie,Hao, Qingru,Tian, Yuwei,Wang, Hui,Zhou, Changlin 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

        Bacterial infections are becoming increasingly difficult to treat due to the increasing number of multidrug-resistant strains. Cathelicidin-BF (BF-30) is a cathelicidin-like antimicrobial peptide and exhibits broad antimicrobial activity against bacteria. In the present study, the antibacterial activity of BF-30 against ciprofloxacin-resistant Escherichia coli and Staphylococcus aureus was examined, and the protective effects of this peptide against these bacteria in rats with bacterial vaginosis were identified for the first time. The data showed that BF-30 had effective antimicrobial activities against ciprofloxacin-resistant E. coli and S. aureus. The minimal inhibitory concentrations for both bacterial strains were $16{\mu}g/ml$, and the minimal bactericidal concentrations were 64 and $128{\mu}g/ml$, respectively. A time course experiment showed that the CFU counts rapidly decreased after BF-30 treatment, and the bacteria were nearly eliminated within 4 h. BF-30 could reduce the fold change (CFU/ml) in local colonization by drug-resistant E. coli and S. aureus to 0.01 at a dose of 0.8 mg/kg/day in the rats' vaginal secretions. In addition, BF-30 induced membrane permeabilization and bound to the genomic DNA, interrupting protein synthesis. Taken together, our data demonstrate that BF-30 has potential therapeutic value for the prevention and treatment of bacterial vaginosis.

      • KCI등재

        BF-30 effectively inhibits ciprofloxacin-resistant bacteria in vitro and in a rat model of vaginosis

        Jing Wang,Bing Li,Yang Li,Jie Dou,Qingru Hao,Yuwei Tian,Hui Wang,Changlin Zhou 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

        Bacterial infections are becoming increasinglydifficult to treat due to the increasing number of multidrugresistantstrains. Cathelicidin-BF (BF-30) is a cathelicidinlikeantimicrobial peptide and exhibits broad antimicrobialactivity against bacteria. In the present study, the antibacterialactivity of BF-30 against ciprofloxacin-resistantEscherichia coli and Staphylococcus aureus was examined,and the protective effects of this peptide against these bacteriain rats with bacterial vaginosis were identified for thefirst time. The data showed that BF-30 had effective antimicrobialactivities against ciprofloxacin-resistant E. coliand S. aureus. The minimal inhibitory concentrations forboth bacterial strains were 16 lg/ml, and the minimal bactericidalconcentrations were 64 and 128 lg/ml, respectively. A time course experiment showed that the CFUcounts rapidly decreased after BF-30 treatment, and thebacteria were nearly eliminated within 4 h. BF-30 couldreduce the fold change (CFU/ml) in local colonization bydrug-resistant E. coli and S. aureus to 0.01 at a dose of0.8 mg/kg/day in the rats’ vaginal secretions. In addition,BF-30 induced membrane permeabilization and bound to thegenomic DNA, interrupting protein synthesis. Taken together,our data demonstrate that BF-30 has potential therapeuticvalue for the prevention and treatment of bacterialvaginosis.

      • KCI등재

        A new interval perturbation method for static structural response bounds using radial basis neural network differentiation

        Yuwei Yao,Liqun Wang,Guolai Yang,Fengjie Xu,Lei Li 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.3

        The interval perturbation method is an effective and successful tool in the uncertainty analysis; however, it suffers from the deficiency in the required differential information, which limits its application in complex engineering problems. To end this, this paper uses the radial basis neural network to formulate the derivative information, and its fine accuracy is demonstrated by a mathematical example. Moreover, a new interval analysis method combining interval perturbation and radial basis neural network differentiation, abbreviated as RBNNIPM is proposed. Furthermore, RBNNIPM is applied to calculate the boundaries of yield stress in a three-bar truss, and the detailed assessment proves that RBNNIPM has both high efficiency and high precision. Finally, an electromagnetic buffer model is established to certificate the practicability of RBNNIPM in practical engineering.

      • KCI등재

        Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis

        Wang Qing,Chen Yong,Shen Xiaofeng,Chen Ji,Li Yuwei 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.6

        Background: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the cartilage regeneration remains unclear. miR-29a-3p is predicted to be a critical target for inhibiting insulin-like growth factor-1 expression and may aggravate the progression of OA. Methods: In this study, we investigated the therapeutic efficacy of intra-articular injection of bone marrow mesenchymal stem cells (BMSCs) transfected with miR-29a-3p inhibitor in OA. Results: miR-29a-3p inhibitor transfection did not influence cell viability of BMSCs, while the chondrogenic differentiation potential of BMSCs was significantly improved. Interestingly, intra-articular injection of BMSCs with miR-29a-3p inhibition significantly prevented articular cartilage degeneration by up-regulating the expression of Sox 9, Col-2a1, aggrecan and down-regulating the expression of matrix metalloproteinase, as well as relieved pain in OA. Conclusion: The double effects on cartilage protection and pain relief indicated a great potential of intra-articular injection of miR-29a-3p inhibitor-transfected BMSCs for the treatment of OA. Background: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the cartilage regeneration remains unclear. miR-29a-3p is predicted to be a critical target for inhibiting insulin-like growth factor-1 expression and may aggravate the progression of OA. Methods: In this study, we investigated the therapeutic efficacy of intra-articular injection of bone marrow mesenchymal stem cells (BMSCs) transfected with miR-29a-3p inhibitor in OA. Results: miR-29a-3p inhibitor transfection did not influence cell viability of BMSCs, while the chondrogenic differentiation potential of BMSCs was significantly improved. Interestingly, intra-articular injection of BMSCs with miR-29a-3p inhibition significantly prevented articular cartilage degeneration by up-regulating the expression of Sox 9, Col-2a1, aggrecan and down-regulating the expression of matrix metalloproteinase, as well as relieved pain in OA. Conclusion: The double effects on cartilage protection and pain relief indicated a great potential of intra-articular injection of miR-29a-3p inhibitor-transfected BMSCs for the treatment of OA.

      • KCI등재

        A Coordinative Control Strategy for Power Electronic Transformer Based Battery Energy Storage Systems

        Yuwei Sun,Jiaomin Liu,Yonggang Li,Chao Fu,Yi Wang 전력전자학회 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.6

        A power electronic transformer (PET) based on the cascaded H-bridge (CHB) and the isolated bidirectional DC/DC converter (IBDC) is capable of accommodating a large scale battery energy storage system (BESS) in the medium-voltage grid, and is referred to as a power electronic transformer based battery energy storage system (PET-BESS). This paper investigates the PET-BESS and proposes a coordinative control strategy for it. In the proposed method, the CHB controls the power flow and the battery state-of-charge (SOC) balancing, while the IBDC maintains the dc-link voltages with feedforward implementation of the power reference and the switch status of the CHB. State-feedback and linear quadratic Riccati (LQR) methods have been adopted in the CHB to control the grid current, active power and reactive power. A hybrid PWM modulating method is utilized to achieve SOC balancing, where battery SOC sorting is involved. The feedforward path of the power reference and the CHB switch status substantially reduces the dc-link voltage fluctuations under dynamic power variations. The effectiveness of the proposed control has been verified both by simulation and experimental results. The performance of the PET-BESS under bidirectional power flow has been improved, and the battery SOC values have been adjusted to converge.

      • KCI등재

        Optimization for testing conditions of inverse gas chromatography and surface energies of various carbon fiber bundles

        Liu Yuwei,Gu Yizhuo,Wang Shaokai,Li Min 한국탄소학회 2023 Carbon Letters Vol.33 No.3

        Surface free energy is an important parameter in surface and interface properties of fiber reinforced polymer composite. The BET (Brunauer, Emmett, and Teller) surface area and surface energy of the sample can be obtained by Inverse Gas Chromatography (IGC) based on the adsorption principle. In this paper, surface energy of carbon fiber bundle was tested by means of IGC under different conditions to find reliable test parameters. The main parameters involved include length, mass, and packing density of sample, target fractional surface coverage, flow rate, and maximum elution time. It is demonstrated that IGC has the advantages of simple sample preparation, stable test data, high automation, and high sensitivity for carbon fiber. Among all test conditions, packing density and flow rate have the greatest influences on the experimental results. The optimized test parameters are suitable for various kinds of carbon fiber bundles, including polyacrylonitrile-based and pitch-based carbon fibers with different tensile properties and tow sizes. Moreover, IGC can acutely characterize the surface properties of carbon fibers after carbon nanotube modification and heat treatment, which are hard to carry out using contact angle method.

      • Ecogenomic responses of benthic communities under multiple stressors along the marine and adjacent riverine areas of northern Bohai Sea, China

        Xie, Yuwei,Hong, Seongjin,Kim, Seonjin,Zhang, Xiaowei,Yang, Jianghua,Giesy, John P.,Wang, Tieyu,Lu, Yonglong,Yu, Hongxia,Khim, Jong Seong Elsevier 2017 CHEMOSPHERE - Vol.172 No.-

        <P><B>Abstract</B></P> <P>Benthic communities in the aquatic ecosystem are influenced by both natural and anthropogenic stressors. To understand the ecogenomic responses of sediment communities to the multiple stressors of polluted environments, the bacteria, protistan and metazoan communities in sediments from marine and adjacent riverine areas of North Bohai Sea were characterized by environmental DNA meta-systematics, and their associations with environmental variables were assessed by multiple statistical approaches. The bacterial communities were dominated by <I>Firmicutes</I> (mean 22.4%), <I>Proteobacteria</I> (mean 21.6%) and <I>Actinobacteria</I> (mean 21.5%). The protistan communities were dominated by <I>Ochrophyta</I> (33.7%), <I>Cercozoa</I> (18.9%) and <I>Ciliophora</I> (17.9%). <I>Arthropoda</I> (71.1%) dominated the metazoan communities in sediments. The structures of communities in sediments were shaped by both natural variables (spatial variability and/or salinity (presented as Na and Ca)) and anthropogenic contaminants, including DDTs, PAHs or metals (Cu, Al, Co, Cr, Cu, Fe, K, Mg, Mn, Ni and Zn). Particularly, the correlation network of multiple communities was modulated by the concentrations of Na and DDTs at the family level. Overall, environmental DNA meta-systematics can provide a powerful tool for biomonitoring, sediment quality assessment, and key stressors identification.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Bacterial, protistan and metazoan communities were characterized with ecogenomics. </LI> <LI> The influences of salinity on benthic communities overwhelmed these of pollutants. </LI> <LI> Variations of community structures also associated with DDTs, PAHs or metals. </LI> </UL> </P>

      • KCI등재

        Influence of the axial radius of rigid arc-shaped rollers in 3D surface rolling

        Xintong Wang,Ming-Zhe Li,Yuwei Liu,Xiang Chang,Weifeng Yang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.8

        The research and development of flexible forming technology have a crucial role in the personalized production and manufacturing of three-dimensional (3D) surface sheet metal parts. Three-dimensional surface rolling with rigid arc-shaped rollers (TSRRAR), a new flexible forming technology, was investigated to effortlessly produce 3D surface parts. Numerical simulation and experimental analysis mainly include data at four values of the difference in axial radius of roller (-2, 2, 6 and 10 mm) to explore this technology’s forming ability. It was demonstrated that various shapes could be obtained only based on one group of rollers. The maximum resultant force decreased from 3.07 to 2.21 KN, and the required maximum compression rate from 4.22 to 2.48 % with the same longitudinal curvature radius (179 mm) to be obtained. Therefore, the forming difficulty can be reduced by selecting the difference in axial radius of roller.

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