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Thi Phuong Diu TRAN(Thi Phuong Diu TRAN ),Thi Van Khanh NGUYEN(Thi Van Khanh NGUYEN ),Thanh Quang DO3(Thanh Quang DO3 ),Cong Nghiep NGUYEN(Cong Nghiep NGUYEN ),Thu Thuy LUONG(Thu Thuy LUONG ) 한국유통과학회 2022 유통과학연구 Vol.20 No.10
Purpose: This article focuses on exploring the associations between job satisfaction, organizational commitment, and turnover intention. Specifically, this study estimates the impacts of Vietnamese employees’ job satisfaction on their organizational commitment and turnover intention in FDI enterprises. Research design, data and methodology: The measures are adapted from previous studies to develop a questionnaire with a seven-point Likert scale. The dataset is directly collected from 227 respondents who are employees at FDI enterprises situated in the North of Vietnam. The dataset is analyzed by quantitative approaches using SPSS 24.0 and AMOS 24.0. Results: The results show that while turnover intention is positively correlated with monthly income, it is negatively correlated with job satisfaction and organizational commitment. Also, organizational commitment is positively associated with job satisfaction among employees at FDI enterprises in Vietnam. Conclusions: The findings of this study will serve as useful references for administrators of FDI enterprises and policymakers to promote employees’ job satisfaction and retain skilled employees.
Tran, Khanh Long,Phung, Xuan Son,Kim, Bao Giang,Phan, Thi Hai,Doan, Thi Thu Huyen,Luong, Ngoc Khue,Pham, Thi Quynh Nga,Nguyen, Tuan Lam,Hoang, Van Minh,Le, Thi Thanh Huong Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1
Evidence shows that tobacco advertising and promotion activities may increase tobacco consumption and usage, especially in youth. Despite the regulation on prohibiting advertisement of any tobacco product, tobacco advertisement and promotion activities are still common in Vietnam. This article presents current exposure to tobacco advertising and promotion (TAP) among school children aged 13 to 15 years in Vietnam in 2014 and potential influencing factors. Data from the Global Youth Tobacco Survey 2014 in Vietnam covering 3,430 school aged children were used. Both descriptive and analytical statistics were carried out with Stata 13 statistical software. Binary logistic regression was applied to explain the exposure to TAP among youth and examine relationships with individual factors. A significance level of p<0.05 and sampling weights were used in all of the computations. In the past 30 days, 48.6% of the students experienced exposure to at least 1 type of tobacco advertising or promotion. Wearing or otherwise using products related to tobacco was the most exposure TAP type reported by students (22.3%). The internet (22.1), points of sales (19.2) and social events (11.5) were three places that students aged 13-15 frequently were exposed to TAP. Binary logistic results showed that gender (female vs male) (OR = 0.61, 95%CI: 0.52 - 0.71), susceptibility to smoking (OR = 2.12, 95%CI: 1.53 - 2.92), closest friends' smoked (OR = 1.43, 95%CI: 1.2 - 1.7) and parents smoking status (OR = 2.83, 95%CI: 1.6 - 5.01) were significantly associated with TAP exposure among school-aged children. The research findings should contribute to effective implementation of measures for preventing and controlling tobacco use among students aged 13-15 in Viet Nam.
Orodispersible film incorporating nanoparticulate loratadine for an enhanced oral bioavailability
Van Nguyen Khanh,Dang Thu Kim,Vu Linh Thi Dieu,Ha Nhan Thi,Truong Hieu Duy,Tran Tuan Hiep 한국약제학회 2023 Journal of Pharmaceutical Investigation Vol.53 No.3
Purpose Loratadine (LOR), a commonly prescribed antihistamine, has low water solubility but high permeability. In this study, an orodispersible film incorporating the nanoparticulate loratadine was prepared to enhance the oral bioavailability of a poorly water-soluble drug. Methods Nanoparticulate loratadine was formulated using the antisolvent precipitation method and optimized by a singlefactor design based on the particle size and polydispersity index. The optimal formulation was spray-dried and characterized by powder X-ray diffraction and differential scanning calorimetry. Nanoparticulate loratadine was loaded into an orodispersible film using a solvent casting method. Results In the dissolution tests, the nanoparticulate loratadine-loaded orodispersible film exhibited a 6.5-fold higher dissolution rate than the pure loratadine-loaded film and a similar dissolution rate compared to the commercialized orodispersible tablet, Loratadine SPM. In pharmacokinetic studies conducted on rats, the maximum concentration (Cmax) and area under the curve of the plasma concentration–time profile from 0 to 24 h (AUC 0-24 h) of the nanoparticulate loratadine-loaded orodispersible film significantly increased 1.8-fold and 5.8-fold, respectively. The elimination half-life (t1//2) increased 5.1-fold compared to the loratadine-loaded counterpart. Conclusion These results suggest the potential of orodispersible films to improve the oral bioavailability of poorly watersoluble drugs and promote compliance in pediatric and geriatric patients.
Van-Hoang Tran,Thanh-Huan Nguyen,Frédéric Plourde,Khanh-Duy Cong Do,Duy-Hung Chung,Cong-Truong Dinh,Gia-Diem Pham 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.2
In order to increase turbine efficiency while retaining structural integrity, modern jet engines need an effective cooling system. Pin-fin arrays play a significant role in the internal cooling system of the turbine blade. In examining the efficacy of cooling techniques using pin-fins, the other papers focus on pin-fin configurations. In contrast, the current study is a step toward optimizing cooling cascade endwalls for better maneuvering and reservation of vortices, which leads to more considerable heat transfer near the endwalls. This study examines the flow field and heat transfer of roughed endwall in the pin-fin channel, including varieties with flat endwall and extruded endwall. The heat transfer of the channel and pressure drop properties of the extruded endwall case are quantitatively assessed to contrast with those of the flat endwalls scenario for an intake Reynolds number range of 7400 to 36000. The leading and trailing surfaces of the channel are divided into five streamwise regions to understand better how well the pin-fins and endwalls transmit heat. The results show that the new endwall construction significantly increases the high heat transfer zones around the pin-fins compared to the flat endwall scenario. In the meantime, the heat transfer of the channel to the pin-fins is enhanced by the modified endwall configuration. The redesigned endwall outperformed the basic case regarding the HTEI, rising by 15.9%. It is found that the friction factor of the new design is increased due to the narrowing channel. However, due to their much higher heat transfer capacity, the HTEI of extruded endwall is up to 41.5% higher than the HTEI of the channel with flat endwalls. These results demonstrate that the heat transfer properties of pin-fins can be significantly improved by optimizing endwall design.
Study on the Characteristics of X-ray Spectra in Imaging Diagnosis Using Monte Carlo Simulations
Khanh Ai Tran,Loan Thi Hong Truong,Nhon Van Mai,Phuong Nguyen Dang,Dung Thi Thuy Vo 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.7
X-rays are widely used in diagnostic imaging such as radiography and computed tomography. An understanding of the X-ray spectrum is essential for estimating the dose absorbed by the patient and for improving image quality. In this research, X-ray emission spectra were investigated by using two different approaches: a Monte Carlo method using the MCNP5 code and a semi-empirical calculation with SpekCalc software. The results were compared with each other to validate the Monte Carlo simulation of the X-ray spectra, so that the simulation model can be applied to estimating the dose rate distribution in X-ray imaging. The obtained results show good agreement between the two approaches, but some divergence is still observed in the characteristic X-ray peaks. In addition, the influence of X-ray tube parameters such as the peak voltage, filter, anode angle and target material on of the beam quality was investigated.
Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam
Vu Van Khien,Duong Minh Thang,Tran Manh Hai,Nguyen Quang Duat,Pham Hong Khanh,Dang Thuy Ha,Tran Thanh Binh,Ho Dang Quy Dung,Tran Thi Huyen Trang,Yoshio Yamaoka 거트앤리버 소화기연관학회협의회 2019 Gut and Liver Vol.13 No.5
Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug in Vietnam. We searched the PubMed, EMBASE, Vietnamese National Knowledge Infrastructure, and Vietnamese Biomedical databases from January 2000 to December 2016. The search terms included the following: H. pylori infection, antibiotic (including clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug) resistance in Vietnam. The data were summarized in an extraction table and analyzed manually. Finally, Excel 2007 software was used to create charts. Ten studies (three studies in English and seven in Vietnamese) were included in this review. A total of 308, 412, 523, 408, 399, and 268 H. pylori strains were included in this review to evaluate the prevalence of H. pylori primary resistance to amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance, respectively. Overall, the primary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 15.0%, 34.1%, 69.4%, 27.9%, 17.9% and 48.8%, respectively. Secondary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 9.5%, 74.9%, 61.5%, 45.7%, 23.5% and 62.3%, respectively. In Vietnam, primary and secondary resistance to H. pylori is increasing over time and affects the effectiveness of H. pylori eradication.