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Pham Hoang Hien(Pham Hoang Hien ),Tran Thanh Tuan(Tran Thanh Tuan ) People&Global Business Association 2023 Global Business and Finance Review Vol.28 No.3
Purpose: This research investigates the role of employee trust and job satisfaction in the relationship between organizational culture and employee loyalty. Design/methodology/approach: The study was conducted among 355 healthcare professionals working in a private healthcare system in southern cities of Vietnam, including doctors, nurses, and other medical staff. The research method employed was partial least squared structure equation modeling (PLS-SEM) with SmartPLS software for data analysis. Findings: The findings indicate that organizational culture has a direct positive impact on employee loyalty and also affects employee trust and job satisfaction positively. Furthermore, employee trust and job satisfaction act as intermediaries and positively influence employee loyalty toward the organization. Research limitations/implications: The research acknowledges the limitation of the limited sample size and encourages further exploration of these relationships in other contexts. In addition, this study provides valuable insights for the management board of private healthcare organizations in southern cities of Vietnam on how to improve employee loyalty by cultivating a positive organizational culture, promoting employee trust, and enhancing job satisfaction. Originality/value: Overall, this research contributes significantly to the existing literature by examining the interplay between employee trust, organizational culture, job satisfaction, and employee loyalty.
Trajectory analyses of uncontrolled circular parachutes in random spatial wind fields
Thanh Dong Pham,Anh Tuan Nguyen,Vu Dan Thanh Le,Trung Kien Nguyen 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.8
The present paper explores the trajectories of two uncontrolled circular parachute models which differ in size and mass in random spatial wind fields. The wind velocity components were generated through three-dimensional inverse fast Fourier transforms; and the correlations of the simulation data compared with the theoretical functions to confirm the accuracy of the wind model. The parachute systems are modelled as six-degrees-of-freedom rigid bodies, on which the aerodynamic forces and moments are applied. The dynamics model was validated before being used to study the drop trajectories of the parachute systems in spatial wind fields. Analyzing the drop trajectories and the impact point dispersion characteristics of the two parachute systems, the paper shows that the smaller one oscillates at a higher frequency and is affected more strongly by the wind. While descending at low altitude, there could be resonance between the dynamics of the larger parachute model and the wind turbulence. Moreover, it is found that the use of simplified vertical wind profiles, which include only the variation of the wind velocity against the altitude, may cause significant error in the simulation results.
A dense, pinholes-free pure cubic phase CsPbBr3 nanocrystals film for high-performance photodetector
Thanh-Tung Duong,Phuong-Nam Tran,Tuan-Pham Van,Duy-Hung Nguyen,Van-Dang Tran 대한금속·재료학회 2024 ELECTRONIC MATERIALS LETTERS Vol.20 No.2
This study demonstrates a simple centrifugal coating method to prepare high-quality pure cubic phase CsPbBr 3 nanocrystalfi lm. The resultant perovskite layers possess a uniform and dense 500 nm-thick, with a bandgap of 2.38 eV, a low trap-statedensity of 6.9 × 10 − 15 cm − 3 , and carrier mobility of approximately 19.8 cm 2 V − 1 s − 1 . Furthermore, CsPbBr 3 NCs-basedself-powered photodetectors with high charge carriers’ charge transfer are fabricated. The device shows a low dark currentdensity of 1.93 × 10 − 7 A/cm 2 at room temperature. Such photodetectors show the highest responsivity of 3.0 AW − 1 ,specifi c detectivity of 1.2 × 10 13 Jones, and external quantum effi ciency (EQE) of 920% at zero bias voltage. The proposedmethod shows signifi cant promise for use in the lab fabrication of optoelectronic devices based on thin fi lms of nanocrystalperovskite materials.
Pham, Tung Thanh,Nguyen, Tiep Tien,Pathak, Shiva,Regmi, Shobha,Nguyen, Hanh Thuy,Tran, Tuan Hiep,Yong, Chul Soon,Kim, Jong Oh,Park, Pil–,Hoon,Park, Min Hui,Bae, Young Kyung,Choi, Jeong Uk,Byun, IPC Science and Technology Press 2018 Biomaterials Vol.154 No.-
<P><B>Abstract</B></P> <P>This study aims to develop a novel surface modification technology to prolong the survival time of pancreatic islets in a xenogenic transplantation model, using 3,4–dihydroxyphenethylamine (DOPA) conjugated poly(lactide–co–glycolide)–poly(ethylene glycol) (PLGA–PEG) nanoparticles (DOPA–NPs) carrying immunosuppressant FK506 (FK506/DOPA–NPs). The functionalized DOPA–NPs formed a versatile coating layer for antigen camouflage without interfering the viability and functionality of islets. The coating layer effectively preserved the morphology and viability of islets in a co–culture condition with xenogenic lymphocytes for 7 days. Interestingly, the mean survival time of islets coated with FK506/DOPA–NPs was significantly higher as compared with that of islets coated with DOPA–NPs (without FK506) and control. This study demonstrated that the combination of surface camouflage and localized low dose of immunosuppressant could be an effective approach in prolonging the survival of transplanted islets. This newly developed platform might be useful for immobilizing various types of small molecules on therapeutic cells and biomaterial surface to improve the therapeutic efficacy in cell therapy and regenerative medicine.</P>
Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives
Tuan Hiep Tran,Raj Kumar Thapa,Hanh Thuy Nguyen,Tung Thanh Pham,Thiruganesh Ramasamy,김동식,용철순,김종오,최한곤 한국약제학회 2016 Journal of Pharmaceutical Investigation Vol.46 No.6
Photodynamic (PDT) and photothermal (PTT) therapy are proven effective strategies for the treatment of cancer. PDT, a photochemistry-based therapy, utilises light energy based photosensitiser for the production of cytotoxic species via electron transfer to biological substrates and potential excitation or energy transfer to molecular oxygen. On the other hand, PTT utilises substances that can convert light energy into heat for efficient tumour ablation. This review provides an insight into the current research investigations of different nanocarriers utilising the synergistic effects of PTT and PDT for anticancer therapy.
( Tuan Hiep Tran ),( Hanh Thuy Nguyeon ),( Tung Thanh Pham ),( Ju Yeon Choi ),( Han Gon Choi ),( Chul Soon Yong ),( Jong Oh Kim ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
Despite tremendous progress in chemotherapy, drug resistance remains a major challenge for anticancer treatment. The combinations of chemo-photothermal and chemo-chemo treatments have been reported to be potential solutions to overcome drug resistance. In this study, we developed a dual-in-dual synergistic therapy based on the use of dual anticancer drug-loaded graphene oxide (GO) stabilized with poloxamer 188 for generating heat and delivering drugs to kill cancer cells under near-infrared (NIR) laser irradiation. The nanocomparable system is stable and uniform in size, generating sufficient heat to induce cell death. Dual drugs (doxorubicin and irinotecan)-loaded GO (GO-Dl) in combination with laser irradiation caused higher cytotoxicity than that caused by the administration of a free single drug as well as a combination of drugs and blank GO in various cancer cells, especially in MDA-MB-231 resistant breast cancer cells. Exposure to "hot" NIR and GO-DI activated the intrinsic apoptosis pathway, which was confirmed based on changes in the morphology of cell nuclei and overexpression of apoptosis-related proteins. On the basis of the results, the combined treatment showed a synergistic effect compared to the effect of chemotherapy or photothermal treatment alone, demonstrating higher therapeutic efficacy to overcome one of the most severe problem in anticancer therapy, that of intrinsic resistance to chemotherapeutics.