Late Ordovician provenance and depositional setting in the southwestern Ordos Block, China: constraints from zircon U-Pb geochronology

Fu Yang,Gang Chen,Yu Kang,Dongmin Ma,Qilin Chen,Tian Tao,Fu Deliang 한국지질과학협의회 2020 Geosciences Journal Vol.24 No.2

The U-Pb ages of single zircon grains contained in the sandstone samples were analyzed by the LA-ICP-MS method, the sediment provenances and geological significance were discussed. The LA-ICP-MS zircon U-Pb dating from the sandstones, tuffaceous sandstones and volcanic tuffs of the Pingliang and Zhaolaoyu Formations along the southwestern Ordos Block are used to limit the maximum depositional age and material sources. The results show that: (1) The youngest ages of zircon dating in the three samples are 445 Ma, 444 Ma and 443 Ma, respectively, suggesting that the studied Formations were deposited in the Late Ordovician. (2) The detrital zircon U-Pb age analysis of the sandstones sample from the Pinliang Formation clustered in the 445–477 Ma, 588–1548 Ma and 1612–2496 Ma with the corresponding youngest peak age of 454.5 ± 3.3 Ma. (3) The distribution of zircon U-Pb age in sandstone samples showing that the sedimentary rocks detritus was mainly sourced from the North Qinling-Qilian terranes and the NCC, and has double provenance supply in the north and south. The material source of the tuffaceous sandstones and volcanic tuffs mainly comes from the volcanic and magmatic activity related to the North Qilian-North Qinling Island Arcs.

Information Fusion Filter for Multi-rate Multi-sensor Systems

Jing Ma,Hao Jin,Tian Tian,Wei Zhang 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.1

This paper is concerned with the information fusion filtering problem for a class of multi-rate multi-sensor systems, where the system is described at the highest sampling rate and different sensors may have different lower sampling rates. Firstly, the local filters (LFs) at state updating points are proposed by using the LFs at measurement sampling points. Then, the distributed suboptimal fusion filter is obtained by the well-known covariance intersection fusion (CIF) algorithm. The filtering error variance matrices are derived to obtain the fusion weights. The computational cost is reduced since the cross-covariance matrices between any two local filters are avoided. Simulation example verifies the correctness and feasibility of the proposed algorithm.

Factors that Influence the Presciption of Antipsychotics for Patients with Schizophrenia in China

Tian-Mei Si,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Chen,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2011 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.9 No.3

Objective: To investigate the patterns of antipsychotic use in China and to analyze the factors that influence antipsychotic prescriptions. Methods: A standardized survey was conducted from May 20 to 24 2002 in five different regions of China with varying economic levels. The patterns of antipsychotic medication use were analyzed in a sample of 4,779 patients with schizophrenia. The survey gathered information on demographic characteristics, clinical profiles, and antipsychotic medications prescribed. Multiple logistic regression was used to analyze factors related to patterns of antipsychotic medication use. Results: A plurality of patients with schizophrenia was treated with clozapine (39%); this was followed by risperidone, sulpride,chlorpromazine, perphenazine, and haloperidol. More than 56.3% of patients were treated with only one atypical antipsychotic. The mean daily dose of chlorpromazine was 365±253 mg (mean±standard deviation), and 6.5% of patients were treated with depot injections of typical antipsychotic medications. A total of 73.7% (n=3,523) of patients with schizophrenia received monotherapy,24.8% (n=1,183) received two antipsychotics, 1.1% (n=52) received three antipsychotics, and one received four different antipsychotics. Patients often simultaneously received other classes of medications including anticholinergic agents, benzodiazepines,β-blockers, antidepressants, and mood stabilizers. Economic status and clinical symptoms were the main factors that contributed to the patterns of antipsychotic prescription. Conclusion: The present study suggests that atypical antipsychotic medications, especially clozapine, are the primary psychiatric treatments of choice in the management of schizophrenia in China. Moreover, the economic status and clinical profile of the patient are the major factors affecting the prescription of antipsychotic medication.

The effect of Glomus intraradices on the physiological properties of Panax ginseng and on rhizospheric microbial diversity

Tian, Lei,Shi, Shaohua,Ma, Lina,Zhou, Xue,Luo, Shasha,Zhang, Jianfeng,Lu, Baohui,Tian, Chunjie The Korean Society of Ginseng 2019 Journal of Ginseng Research Vol.43 No.1

Background: Glomus intraradices is a species of arbuscular mycorrhizal fungi that, as an obligate endomycorrhiza, can form mutually beneficial associations with plants. Panax ginseng is a popular traditional Chinese medicine; however, problems associated with ginseng planting, such as pesticide residues, reduce the ginseng quality. Methods: In this experiment, we studied the effect of inoculating G. intraradices on several physiological properties and microbial communities of ginseng. UV-Visible Spectrum method was used to detect physical properties. Denaturing gradient gel electrophoresis method was used to analyze microbial communities. Results: The results indicated that inoculation with G. intraradices can improve the colonization rate of lateral ginseng roots, increase the levels of monomeric and total ginsenosides, and improve root activity as well as polyphenol oxidase and catalase activities. We also studied the bacterial and fungal communities in ginseng rhizospheric soil. In our study, G. intraradices inoculation improved the abundance and Shannon diversity of bacteria, whereas fungi showed a reciprocal effect. Furthermore, we found that G. intraradices inoculation might increase some beneficial bacterial species and decreased pathogenic fungi in rhizospheric soil of ginseng. Conclusion: Our results showed that G. intraradices can benefit ginseng planting which may have some instructive and practical significance for planting ginseng in farmland.

Identification and expression analysis of the E2F/DP genes under salt stress in Medicago truncatula

Tian-Yi Ma,Jing Guo,Zi-Wei Li,Shu-Yong Zhang,Guo-Ting Liang 한국유전학회 2014 Genes & Genomics Vol.36 No.6

Cell cycle control in plants converges on theRb/E2F/DP pathway, which is regulated by cyclin-dependentkinases. Plants can coordinate their cell cycles duringsalt stress to benefit their growth and development. However,the mechanism underlying cell cycle control undersalt stress is still unclear. Here, we identified five predictedE2F/DP genes in the Medicago truncatula genome,including three E2Fs, one DP, and one DEL. The conserveddomains of the E2F/DP proteins were relativelywell conserved with those of Arabidopsis thaliana andOryza sativa. Intron/exon organization analyses indicatedthat Medtr;E2Fc and Medtr;DPa gained/lost introns in theconserved domains during recent evolutionary process. Furthermore, an expression analysis showed that thesegenes were expressed with varied transcription levels in allof the tissues tested. Contrasting gene expression changesin response to salt treatment in salt-tolerant versus saltsensitivegenotypes indicated that Medtr;DPa might be acandidate gene underlying the salt tolerance. This studywill contribute to the understanding of the E2F/DP transcriptionfactors in M. truncatula and of the mechanismorganizing cell cycle regulation and salt stress.

Multi-objective Optimization of a Hydrogen-Battery Hybrid Storage System for Offshore Wind Farm Using MOPSO

Tian Tian,Ma Zetao,Cui Qiong,Shu Jie,Tan Lei,Wang Hao 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.6

Recently, offshore wind farms (OWFs) are gaining more and more attention for its high efficiency and yearly energy production capacity. However, the power generated by OWFs has the drawbacks of intermittence and fluctuation, leading to the deterioration of electricity grid stability and wind curtailment. Energy storage is one of the most important solutions to smooth the wind power and capture its surplus. In this paper, we provide a multi-objective optimization approach that combines multi-objective particle swarm optimization and rule-based energy management strategy for an on-gird offshore wind-hydrogen-battery system to simultaneously address the economic (Eco), the qualified rate of smoothing offshore wind power fluctuations (QRS), and the rate of offshore wind power curtailment (ROC). Results revealed that ROC and Eco, QRS and Eco are negatively correlated, but ROC and QRS are positively correlated. The hybrid storage system is more conducive to improve QRS and reduce ROC. Comparing with other three systems, the improvement range for ROC is between 13.6 and 46% when QRS is 100%. In addition, battery storage improves QRS by 2.6%, hydrogen storage deteriorates Eco by 86.8% and improve ROC by 38.5%, the change of ROC and QRS brings by transmission project are close to 100% and 4.4%.

Use of Clozapine for the Treatment of Schizophrenia: Findings of the 2006 Research on the China Psychotropic Prescription Studies

Tian-Mei Si,Yun-shu Zhang,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Cheng,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2012 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.10 No.2

Objective: Clozapine is one of the most commonly used antipsychotic drugs in China. To date, few studies have investigated the patterns the prescription of clozapine nationwide. The present study examined these patterns in China in 2006 and identified the demographic and clinical characteristics associated with the use of clozapine. Methods: Using a standardized protocol and data collection procedure, we surveyed 5,898 patients with schizophrenia in 10provinces with differing levels of economic development. Results: Overall, clozapine had been prescribed for 31.9% (n=1,883) of the patients; however we found considerable variation among the 10 provinces. The frequency of clozapine use was highest in Sichuan (39.3%) and lowest in Beijing (17.3%). The mean daily dose of clozapine was 210.36±128.72 mg/day, and 25.1% of the patients were treated with clozapine in combination with other antipsychotics. Compared with the group not receiving clozapine, clozapine-user had been treated for longer durations and had experienced a greater number of relapses and hospitalizations. Furthermore, those in the clozapine-user had lower family incomes, were less able to seek psychiatric services, and more likely to be male and have a positive family history of schizophrenia. A multiple logistic regression analysis revealed that age, sex, professional help-seeking behaviors, duration of illness, economic status, educational level, and clinical manifestations were associated with the use of clozapine. Conclusion: Clozapine use is common in China. However, use of the antipsychotic varies among provinces, and demographic and clinical factors play important roles in the prescription of clozapine.

Association Between MDM2 SNP309 T>G and Risk of Gastric Cancer: A Meta-analysis

Tian, Xin,Tian, Ye,Ma, Ping,Sui, Cheng-Guang,Meng, Fan-Dong,Li, Yan,Fu, Li-Ye,Jiang, Tao,Wang, Yang,Ji, Fu-Jian,Fang, Xue-Dong,Jiang, You-Hong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Background: As a negative regulator of P53, MDM2 plays an important role in carcinogenesis; a polymorphism in its promoter region. SNP309 T>G, is known to increase the expression of MDM2, thus being considered related to higher susceptibility to neoplasia. However, no agreement has been achieved regarding its effects on gastric cancer. Methods: The present systematic meta-analysis was performed based on comprehensive literature search from Pubmed, Web of science and CBM databases. Results: It was suggested from 6 independent studies that the GG genotype is associated with a significantly increased risk of gastric cancer (Recessive: OR = 1.43, 95% CI = 1.08-1.91, P = 0.013), and subgroup analysis also confirmed the relationship (English publications-recessive model: OR = 1.45, 95% CI = 1.10-1.91, P = 0.009; Studies in China-recessive model: OR = 1.58, 95% CI = 1.08-2.30, P = 0.017). No publication bias was detected. Conclusion: The meta-analysis indicated a significant inverse association between GG genotype carriage and elevated risk of gastric cancer. However, more studies and detailed information are needed to fully address the topic.

비선형동적해석에 의한 프리스트레싱 프레임공법으로 보강된 R/C건물의 내진보강효과의 평가

마란천 ( Ma Lan-tian ),정주성 ( Jung Ju-seong ),최윤철 ( Choi Yun-chul ),이강석 ( Lee Kang-seok ) 한국구조물진단유지관리공학회 2021 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.25 No.2

본 연구에서는 보강프레임에 프리스트레싱을 통해 기존구조체와 일체거동이 가능한 프리스트레싱 프레임공법(Pre-stressing Frame Method, 이하 PSF)을 제안하였다. 2층 골조 유사동적실험을 통해 내진보강효과를 검증함과 동시에, 비선형동적해석을 이용하여 유사동적 실험결과와 비교하여 해석모델링을 구축하였다. 추후 구축된 비선형 동적해석 모델링을 기반으로 비내진상세를 가지는 철근콘크리트(이하, R/C) 건축물을 대상으로 비선형동적해석을 실시할 계획이며, 내진보강 전과 후의 건축물의 지진응답하중 및 응답변위 특성을 검토하여 내진보강효과를 검증이 필요하다고 판단된다.

Identification and Characterization of Protein Encoded by orf382 as L-Threonine Dehydrogenase

( Fei Ma ),( Tian Wen Wang ),( Xing Yuan Ma ),( Ping Wang ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.6

In the genome annotation of Escherichia coli MG1655, the orf382 (1,149 bp) is designated as a gene encoding an alcohol dehydrogenase that may be Fe-dependent. In this study, the gene was amplified from the genome by PCR and overexpressed in Escherichia coli BL21(DE3). The recombinant 6×His-tag protein was then purified and characterized. In an enzymatic assay using different hydroxyl-containing substrates (n-butanol, L-threonine, ethanol, isopropanol, glucose, glycerol, L-serine, lactic acid, citric acid, methanol, or D-threonine), the enzyme showed the highest activity on L-threonine. Characterization of the mutant constructed using gene knockout of the orf382 also implied the function of the enzyme in the metabolism of L-threonine into glycine. Considering the presence of tested substrates in living E. coli cel ls and previous literature, we believed that the suitable nomenclature for the enzyme should be an L-threonine dehydrogenase (LTDH). When using L-threonine as the substrate, the enzyme exhibited the best catalytic performance at 39°C and pH 9.8 with NAD+ as the cofactor. The determination of the Km values towards L-threonine (Km = 11.29 μM), ethanol (222.5 μM), and n-butanol (8.02 μM) also confirmed the enzyme as an LTDH. Furthermore, the LTDH was shown to be an ion-containing protein based on inductively coupled plasma-atomic emission spectrometry with an isoelectronic point of pH 5.4. Moreover, a circular dichroism analysis revealed that the metal ion was structurally and enzymatically essential, as its deprivation remarkably changed the α-helix percentage (from 12.6% to 6.3%).