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      • KCI등재

        Comparison between predicted and measured resting energy expenditures in Korean male collegiate soccer players

        이시형,Kuniko Moto,오태웅,Motoko Taguchi 한국운동영양학회 2022 Physical Activity and Nutrition (Phys Act Nutr) Vol.26 No.3

        [Purpose] This study aimed to evaluate the differences between predicted resting energy expenditure (REE), using fat-free mass (FFM)-based prediction equations, and measured REE in Korean male collegiate soccer players. [Methods] Fifteen male collegiate soccer players (18- 21 years) participated in this study. The REE measurements were conducted using the Douglas bag method. Body composition was measured by dual-energy X-ray absorptiometry (DXA). The differences between the measured REE and predicted REE, using the five FFM-based REE equations, were analyzed using the t-test, calculation of errors, regression analysis, and the Bland-Altman method. [Results] The Cunningham (1980) and ten Haaf and Weijs (2014) equations showed significantly overestimated REE (1,808 ± 99 kcal/d, p <0.01; 1,838 ± 103 kcal/d, p <0.01; respectively), but the Owen (1988), Taguchi (2011), and Kim (2015) equations’ estimations were not significantly different from the measured REE (1,589 ± 106 kcal/d, 1,640 ± 124 kcal/d, and 1,622 ± 68 kcal/d, respectively). The Taguchi equation gave the best prediction of REE with the lowest constant error (-6 ± 125) and effect size (-0.05), and a non-significant proportional bias (p = 0.95). [Conclusion] The Taguchi equation is recommended for predicting REE in Korean collegiate soccer players. The selection process of a REE-prediction equation must take into consideration the target population’s characteristics. Future studies are recommended to evaluate the validity of the different FFM-based REE-prediction equations in various Korean athletes.

      • SCOPUSKCI등재
      • Risk Factors for Clinical Metastasis in Men Undergoing Radical Prostatectomy and Immediate Adjuvant Androgen Deprivation Therapy

        Taguchi, Satoru,Fukuhara, Hiroshi,Kakutani, Shigenori,Takeshima, Yuta,Miyazaki, Hideyo,Suzuki, Motofumi,Fujimura, Tetsuya,Nakagawa, Tohru,Igawa, Yasuhiko,Kume, Haruki,Homma, Yukio Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

        Background: Adjuvant androgen deprivation therapy (ADT) is a treatment option for prostate cancer (PC) patients after radical prostatectomy (RP). Although it can achieve a good progression-free survival rate, some patients still develop clinical metastasis. We here investigated risk factors of clinical metastasis in post-prostatectomy patients who received immediate adjuvant ADT. Materials and Methods: We identified 197 patients with non-metastatic PC who underwent RP at our institution between 2000 and 2012, followed by adjuvant ADT. The associations of various clinicopathologic factors with clinical metastasis (primary endpoint) and cancer-specific survival (secondary endpoint) were assessed. Multivariate analysis was conducted using a Cox proportional hazards model. Median follow-up was 87 months after RP. Results: Nine (4.6%) patients developed clinical metastasis and six (3.0%) died from PC. Eight of nine metastatic patients had a pathologic Gleason score (GS) 9 and developed bone metastasis, while the remaining one had pathologic GS 7 and developed metastasis only to para-aortic lymph nodes. On multivariate analyses, pathologic GS ${\geq}9$ and regional lymph node metastasis (pN1) were independent predictors of clinical metastasis and pathologic GS ${\geq}9$ was an independent predictor of cancer-specific death. Conclusions: Pathologic GS ${\geq}9$ and pN1 were independent predictors of clinical metastasis in post-prostatectomy patients who received immediate adjuvant ADT. Furthermore, pathologic GS ${\geq}9$ was an indispensable condition for bone metastasis, which may imply that patients with GS ${\leq}8$ on adjuvant ADT are unlikely to develop bone metastasis.

      • KCI등재

        Synthesis of carbon materials with extremely high pyridinic-nitrogen content and controlled edges from aromatic compounds with highly symmetric skeletons

        Taguchi Taisei,Gohda Syun,Gotoh Kazuma,Sato Satoshi,Yamada Yasuhiro 한국탄소학회 2023 Carbon Letters Vol.33 No.4

        Selective doping of pyridinic nitrogen in carbon materials has attracted attention due to its significant properties for various applications such as catalysts and electrodes. However, selective doping of pyridinic nitrogen together with controlling skeletal structure is challenging in the absence of catalysts. In this work, four precursors including four fused aromatic rings and pyridinic nitrogen were simply carbonized in the absence of catalysts in order to attain mass synthesis at low cost and a high percentage of pyridinic nitrogen in carbon materials with controlled edges. Among four precursors, dibenzo[f,h]quinoline (DQ) showed an extremely high percentage of pyridinic nitrogen (96 and 86%) after heat treatment at 923 and 973 K, respectively. Experimental spectroscopic analyses combined with calculated spectroscopic analyses using density functional theory calculations unveiled that the C-H next to the pyridinic nitrogen in DQ generated gulf edge structures with controlled pyridinic nitrogen after carbonization. By comparing the reactivities among the four precursors, three main factors required for maintaining the pyridinic nitrogen in carbon materials with controlled edges, such as (1) high thermal stability of the pyridinic nitrogen, (2) the presence of one pyridinic nitrogen in one ring, and (3) the formation of gulf edges including pyridinic nitrogen to protect the pyridinic nitrogen by the C-H groups on the gulf edges, were revealed.

      • KCI등재후보

        Antiresorptive agent-related osteonecrosis of the jaw in osteoporosis patients from Asian countries

        Akira Taguchi,Masataka Shiraki,Archie Morrison,Aliya A. Khan 대한골다공증학회 2017 Osteoporosis and Sarcopenia Vol.3 No.2

        Bisphosphonate (BP)-associated osteonecrosis of the jaw (ONJ) was first reported in oncology patients in 2003 and subsequently in osteoporosis patients in 2004. Since oral surgical procedures, such as tooth extraction, are also considered one of the major risk factors for ONJ, there is confusion among physicians, dentists, and patients e particularly osteoporosis patients currently taking BPs e regarding the safety of remaining on therapy surrounding these procedures. Many papers about BP-related ONJ (BRONJ) have been published to date. In addition to BRONJ, recent studies have reported an association between ONJ and the antiresorptive therapy denosumab (Dmab; a RANKL-inhibitor). BRONJ and Dmab-related ONJ are together referred to as antiresorptive agent-related ONJ (ARONJ). The pathogenesis of ARONJ still remains unknown. It is forecasted that there will be an increased incidence of patients with osteoporotic fractures and an increased number of prescriptions for antiresorptive agents in Asia in the future. However, prescriptions for antiresorptives for osteoporosis may be restricted in the Asian population as the occurrence of ARONJ may be higher as compared with those in other countries. In this review, we focused on the following topics as it pertains to the Asian osteoporotic population: the oral condition specific for osteoporosis patients; definition, staging, prevalence and incidence of ARONJ; imaging modalities for ARONJ; specific risk factors for ARONJ; prevention strategies for ARONJ, and; cooperation between physicians and dentists in the prevention of ARONJ. Ideally, the Asian Federation of Osteoporosis Societies would cooperate with one another and find more population-specific evidence for the prevention of ARONJ.

      • KCI등재

        Impact of loop-tail ureteral stents on ureteral stentrelated symptoms immediately after ureteroscopic lithotripsy: Comparison with pigtail ureteral stents

        Makoto Taguchi,Takaaki Inoue,Kouei Muguruma,Takashi Murota,Hidefumi Kinoshita,Tadashi Matsuda 대한비뇨의학회 2017 Investigative and Clinical Urology Vol.58 No.6

        Purpose: To evaluate urination-related quality of life (QoL) in patients with an indwelling ureteral stent immediately after ureteroscopic lithotripsy (URSL) for upper urinary calculi. We compared the effects of loop-tail and pigtail ureteral stents on urination-related QoL. Materials and Methods: Of 135 patients who underwent URSL between May 2014 and March 2015 at our hospital, we retrospectively analyzed the records of 70 patients (42 men, 28 women; median age, 63 years) in whom the stent tail was positioned inside the bladder without crossing the midline and who completed the core lower urinary tract symptoms score (CLSS) questionnaire pre- and postoperatively. Results: There were significant differences in incomplete emptying (p=0.048) and bladder pain (p=0.041) between patients with loop-tail versus pigtail ureteral stents after URSL. In the multivariate analysis, stent type had a stronger association with incomplete emptying (p=0.022) and bladder pain (p=0.018) than age, sex, body mass index, stent side, operation time, diameter of ureteral access sheath, and stent type. Conclusions: Patients with loop-tail ureteral stents had better urination-related QoL in the immediate post-URSL stage than patients with pigtail stents.

      • KCI등재

        Smad3 deficiency accelerates tongue wound healing via epithelial cell-extracellular matrix interactions

        Chieko Taguchi,Fuyuki Sato,Chen Wang,Shigeru Nakamura,Kosuke Oikawa,Ujjal Kumar Bhawal,Hiroyuki Okada,Kazumune Arikawa 조선대학교 치의학연구원 2022 Oral Biology Research (Oral Biol Res) Vol.46 No.4

        Aberrant wound closure occurs in a broad range of wounds and scars, and the altered regulation of transcription factors in wound areas can account for both of those conditions. This study aimed to explore the function of the transcription factor Smad3 in wound healing using a tongue wound model in Smad3 knockout (Smad3–/–) mice and with Smad3 small interfering RNA (siRNA) transfected human gingival fibroblasts (HGFs). Smad3 –/–mice were used to examine the extent of repair in tongue wounds. Cell migration was evaluated in HGFs using wound healing assays. The mRNA expression levels of Sox2, E-cadherin, fibronectin, and vimentin were examined in HGFs using reverse transcription-quantitative polymerase chain reaction. Histopathological analysis of wound closure in Smad3–/– mice showed rapid re-epithelialization and remodeling in tongue wound repair compared with Smad3+/+ mice. Increased numbers of neutrophils were identified in the wounds of Smad3 –/– mice. Sox2 and phospho-E-cadherin expression levels were increased in Smad3–/– mice. Smad3 knockdown by siRNA increased cell migration of HGFs. In addition, Sox2, E-cadherin, fibronectin, and vimentin mRNA levels were significantly increased in Smad3 siRNA-transfected HGFs compared with controls. Collectively, these findings demonstrate that a Smad3 deficiency can expedite wound healing and increase immune reactions and extracellular matrix formation after tongue injuries, boosting recovery through Sox2 and E-cadherin. Consequently, Smad3 inhibition would help stimulate tongue wound healing.

      • KCI등재

        Characterization of Microstructure and Mechanical Properties of High-Purity Iron Added with Copper

        ( O Taguchi ),( Su Yeon Lee ),( M Uchikoshi ),( M Isshiki ),( Chan Gyu Lee ),( S Suzuki ),( Vladimir S Gornakov ) 한국열처리공학회 2012 熱處理工學會誌 Vol.25 No.1

        An influence of the addition of copper (0.5, 1.0 and 1.5 mass% Cu) on the microstructure and mechanical properties of high purity iron (99.998 mass%) was characterized. The microstructure and microhardness of high-purity iron based samples, which were rolled at room temperature and subsequently annealed, were investigated in this work. The microstructure of the samples has been observed by electron back scattering diffraction (EBSD) and the mechanical properties have been studied by using micro-Vickers hardness test. The results of microstructural observation showed that deformation band was formed in high purity iron by rolling at room temperature, and it was recovered by annealing up to about 900 K. The microhardness results showed that the softening of high-purity iron occurred by annealing up to about 900 K, while the hardness of iron added with about 0.5-1.5 mass% copper was kept over 100 Hv and at the early time of annealing reached a maximum. The hardness of iron added with a small amount of copper may be attributed to precipitation hardening as well as solution hardening. The orientation of crystal in recrystallized grain was almost same as that of deformed grain. (Received November 21, 2011; Revised December 28, 2011; Accepted January 19, 2012)

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