발치후 임프란트 매식 시기에 따른 골유착에 관한 연구 : Histomorphometric and Biomechanical Studies 조직형태계측학적 및 생역학적 연구

오희균,류선열 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.4

The purpose of this study was to investigate the effect of timing of implant insertion on osseointegration after tooth extraction. Fifteen mongrel dogs, weighing 15kg or more, were used. The lower right 1st, 2nd, 3rd, 4th premolars and 1st molar were extracted under general anesthesia. Implants were inserted at 2, 4, and 8 weeks after extraction of the teeth, being designated as 2-, 4-, and 8-week groups, respectively. Results obtained were as follows. 1. Macroscopically there was neither an infection at the implant site nor an exposure of the implant. 2. Histologically the surrounding bone of the implant was less mature in the 2-week group than in the 4- and 8-week groups. 3. The implant-bone contact ranged from 75 to 82%, with no significant differences among the groups. No increase in the implant-bone contact was found with increasing healing periods from 4 to 12 weeks after implant insertions. 4. The average depth (0.64mm) of the fibrous connective tissue ingrowth in the 2-week group was slightly deeper than those in the 4- (0.51mm) and 8-week (0.53mm) groups at 12 weeks after implant insertion. 5. the implant-bone interfacial bond strengths were 73.05kgf in the 2-week group, 69.71 kgf in the 4-week group and 73.76 kgf in the 8-week group. No significant difference was noted in pullout force among the groups. The degree of confidence of interfacial bone strength was highest in the 8-week group, followed by the 4- and 2-week groups. These results indicate that at least 4 weeks of healing period will be required before implant is to be inserted following tooth extraction.

구내 신연장치를 이용한 치조골 신연에 미치는 잠복기의 영향

오유근,오희균,유선열 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.4

The present study was aimed to investigate the effects of latency period on alveolar ridge distraction using the intraoral distraction device, Nine adult mongrel dogs of either sex, weighing about 15kg, were used. They were divided into 3-day, 5-day, and 7-day groups according to the latency period. The left upper and lower premolars and first molars were extracted, Twelve weeks after the extraction, an osteotomy was performed and the distraction device was applied. After the latency period, the distraction was applied at a rate of 1.2mm for 8 days. The distraction device was left in place for 2 weeks to allow consolidation and was then removed. The animals were sacrified at 8 weeks after completion of distraction and were examined macroscopically, radiographically, and histologically. After completion of the distraction, the alveolar crest protruded prominently, showing the vertical augmentation of the alveolar bone. Soft tissues were broken down after the 6th day of distraction in 3-day latency group, and premature union occurred on the 7th day of distraction in the 7-day latency group. The average distance was 9.40±0.3mm in 3-day latency group, 9.35±0.1mm in 5-day latency group, and 8.85±0.1mm in 7-day latency group. In the radiograph taken at 8 weeks after distraction, there was slight bone resorption around the medial and distal edges of the alveolar bone segment, and a new bone deposition was observed in the neighboring alveolar crest area in all groups. Fibrous tissues were present in a part of the buccal cortical bone area of the distraction gap, and the woven and lamellar bones were observed in the distracted gap. There were bony bridges in the distraction gap in all animals examined. These results suggest that optimal time of latency period on alveolar ridge distraction using the intraoral distraction device is about 5 days in dogs, and about 7days in human beings.

상악골에 발생한 치성각화낭종

오선영,김수관,류종회,박인순 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

We described two cases of odontogenic keratocysts of the maxilla. Odontogenic keratocysts (OKCs) are jaw cysts with a proclivity for local invasion and recurrence. Clinically, OKCs are characterized by aggressive, local growth, The diagnosis of mandibular OKC is based on physical examination and plain film radiographic findings. However, histopathological confirmation is required to make the diagnosis with certainty. The molar regions of the mandible and maxilla are the principal primary locations. The maxillary antrum is also a common site. Initial therapy is typically enucleation with or without extraction of the associated teeth. Long-term follow-up is necessary because of the aggressive nature and recurrence rate of OKC.

구내 신연장치를 이용한 치조골 신연에 미치는 잠복기의 영향

오유근,유선열 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1

The present study was aimed to investigate the effects of latency period on alveolar ridge distraction using the intraoral distraction device. Nine adult mongrel dogs of either sex, weighing about 15 kg, were used. They were divided into 3-day, 5-day, and 7-day groups according to the latency period. The left upper and lower premolars and first molars were extracted. Twelve weeks after the extraction, an osteotomy was performed and the distraction device was applied. After the latency period, the distraction was applied at a rate of 1.2mm for 8 days. The distraction device was left in place for 2 weeks to allow consolidation and was then removed. The animals were sacrified at 8 weeks after completion of distraction and were examined macroscopically, radiographically, and histologically. After completion of the distraction, the alveolar crest protruded prominently, showing the vertical augmentation of the alveolar bone. Soft tissues were broken down after the 6th day of distraction in 3-day latency group, and premature union occurred on the 7th day of distraction in the 7-day latency group. The average distance was 9.40±0.3mm in 3-day latency group, 9.35±0.1mm in 5-day latency group, and 8.85±0.1mm in 7-day latency group. In the radiograph taken at 8 weeks after distraction, there was slight bone resorption around the medial and distal edges of the alveolar bone segment, and a new bone deposition was observed in the neighboring alveolar crest area in all groups. Fibrous tissues were present in a part of the buccal cortical bone area of the distraction gap, and the woven and lamellar bones were observed in the distracted gap. There were bony bridges in the distraction gap in all animals examined. These results suggest that optimal time of latency period on alveolar ridge distraction using the intraoral distraction device is about 5 days in dogs, and about 7days in human beings.

흰쥐 악하선에서 배설관 폐쇄에 따른 나트륨 운반체 발현의 변화 : Ligated Submandibular Gland in Rats

오유근,유선열 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.4

Although acinar atrophy frequently occurs and the salivary secretory activity is significantly decreased in various salivary glandular diseases, their underlying molecular mechanisms have not been established. The present study was aimed to increase our understanding of functional alterations associated with pathological acinar atrophy. Male Sprague-Dawley rats weighing 180-200g were used. Their left submandibular ducts were ligated for 1 week, and the expression of sodium transporters related to the salivary formation was determined in the gland. The ligated gland was significantly decreased in its weight. The expressions of α_(1) and β_(1) subunits of Na, K-pump determined by Western blot analysis were increased in the experimental group. Accordingly, the catalytic activity of Na, K-pump was increased. The expressions of α, β, and γ subunits of BNaC were increased. The expression of TSC was also increased. The mRNA expression of mineralocorticoid receptor determined by reverse transcription-polymerase chain reaction was decreased in the experimental group. These results suggest that the changes in sodium transporters are causally related with an increased intraluminal pressure in the salivary duct in the ligated gland.

이하선 종양에 관한 임상적 연구

백승,오희균,박홍주,유선열,김원재 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.3

This is a clinical study on 113 patients, who were treated for parotid tumors at Chonnam National University Hospital over a period of 5 years from January 1996 to December 2000. The results were as follow, 1. The mean ages were 42.6 years old (12~73 years) for benign parotid tumor patients and 43.9 years old (2~74 years) for malignant patients. 2. The ratio of male to female was 1:2 in malignant parotid tumors, but there was no difference in sex distribution of benign tumor. 3. There was no difference in mean mass size and duration of illness between benign and nalignant tumor patients. 4. The combined use of fine needle aspiration biopsy and computed tomograph was common as the diagnostic method of parotid tumor 5. The parotid tumors were commonly located in the superficial lobe(69%). 6. The ratio of benign and malignant tumors was 4:1. The most common benign tumor was pleomorphic adenoma (72% of benign tumor), followed by Warthin's tumor and monomorphic adenoma. The most common malignant tumor was rnucoeplderrnoid carcinoma(45% of malignant tumor). followed by adenoid cystic carnoma. carcinoma ex pleomorphic adenoma, and adenocarcinoma. 7. The most common operations were superficial parotidectomy (72%) for benign parotid tumor and total parotidectomy (45%) for malignant tumor 8. The most common postoperative complication was temporary facial nerve weakness (82%), followed by Frey's syndrome (14%) and permanent facial palsy (4%). 9. Postoperative radiation therapy was done in 12 patients and the mean radiation dose was 5550±620cGy. 10. Of 113 cases. tumor recurrence developed in 12 cases (10%). These results suggest that the successful management of parotid gland tumors needs adequate surgical treatment on the basis of knowledge of parotid gland anatomy and preoperative diagnosis.

광중합 복합레진의 색안정성 및 투명도변화에 관한 가속시험

황인남,오원만,류선열 전남대학교 치과대학 1992 전남치대논문집 Vol.4 No.1

Color stability of tooth colored restorative resins is an important factor, particularly in anterior teeth restoration. The purpose of this study was to evaluate the color stability and opacity change of several light curing composite resins. Specimens of eight composite resins(Prisma AP.H, Brilliant Enamel, Charisma, Durafil, Helio Progress, Herculite XR, P-50 and Silux Plus) were divided into two groups : In Group 1, the specimens were polymerized by visible light curing unit for 60 seconds on both sides and in Group 2, the post-cured specimens were heat tempered by light/heat curing unit for 45 units(about 18 min.). All specimens were stored in distilled water at 60℃ for 30 days. The color characteristics(L^*, a^*, b^*) and opacity of the specimens before and after immersion were measured by spectrocolorimetry and the total color difference(ΔE^*) and opacity change(ΔY%) were computed. The results obtained were as follows: 1. SP and APH in both groups, DF, HP and HXR in Group Ⅰ showed ΔE^*-value above 2.0. 2. DF, HP, SP and HXR in Group Ⅰ showed higher ΔE^*-value than in Group 2, but the others had no significant difference. 3. The opacity of CH and HXR in Group Ⅰ, and of CH and BE in Group 2 decreased after immersion, while that of the others increased. 4. Opacity change of BE, P50 and HXR was significantly different between Group Ⅰ and 2. These results suggest that color change in the post-cure heat tempered specimens by light/heat curing unit was smaller than that of the specimens polymerized by visible light curing unit. No clinically detectable opacity changes were noted for any materials in either group.

가토 대퇴정맥에서 헤파린 국소 적용과 혈관냉동이 미세혈관문합부 혈전 형성에 미치는 영향

김지영,오희균,유선열,김선헌 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

The effect of topical heparin application and vascular freezing on thrombosis was evaluated in the femoral vein of rabbits. The femoral veins were crushed, incised transverersely and treated by 4 different ways; 1) group 1, heparin treated only, 2) group 2, frozen only, 3) group 3, heparin treated and frozen,4) group 4, treated with saline as control. The patency was evaluated by empty-and-refill test and thrombus formation was judged by stereoscopic and SEM observation. The results obtained were as follows : 1.Thirty minutes after suture, the patency was more improved in the three groups than the control, but there was no significant difference among groups. 2.Three days after suture, the patency was more improved in the three groups than the control, and was prominent in group 1 and group 3 (P<0.05). 3.Significantly reduced thrombus could be seen in most case of group 3. These results suggest that topical application of heparin and vascular freezing is effective in

악골에 발생한 악성 섬유성조직구종 2례

정종철,최홍란,오희균,박준아,류선열,이종호,김영운,정숭룡 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Malignant fibrous histiocytoma rarely occurs in the jaws. Although the histogenesis of this tumor remains controversal, it is best regarded as a primitive and pleomorphic nature reflected by collagen production and occasional phagocytosis. It is common for metastatic foci to appear in lung and regional lymph node. There are variable treatments such as radiotherapy, surgical excision or combination, therapy of surgical excision, chemotherapy and radiotherapy. With the review of literatures, the authors report the clinical study of two cases of malignant fibrous histiocytoma of the jaw.

이하선 종양에 관한 임상적 연구

백승,하주원,오희균,유선열,김원재 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.5

This is clinical study on 113 patients who were treated for parotid tumors at Chonnam National University Hospital over a period of 5 years from January 1996 to December 2000. The results were as follows ; The mean ages were 42.6 years old (12∼73 years) for benign parotid tumor patients and 43.9 years old (2∼74 years) for malignant patients. The ratio of male to female was 1:2 in malignant parotid tumors, but there was no difference in benign tumors. There was no difference in mean mass size and duration of illness between benign and malignant tumor patients. The combined usage of fine needle aspiration biopsy and computed tomogram was common as the diagnostic methods of parotid tumor. The parotid tumors were commonly located in the superficial lobe (69%). The ratio of benign and malignant tumors was 4:1. The most common benign tumor was pleomorphic adenoma (72% of benign tumor), followed by Warthin's tumor and monomorphic adenoma. The most common malignant tumor was mucoepidermoid carcinoma (45% of malignant tumor), followed by adenoid cystic carnoma, carcinoma ex pleomorphic adenoma, and adenocarcinoma. The most common operations were superficial parotidectomy (72%) for benign parotid tumor and total parotidectomy (45%) for malignant tumor. The most common postoperative complication was temporary facial nerve weakness (82%), followed by Frey's syndrome (14%) and permanent facial palsy (4%). Postoperative radiation therapy was done in 12 patients (60%) and the mean radiation dose was 5550±620 cGy. Of 113 cases, tumor recurrence developed in 12 cases (10%). These results suggest that the successful management of parotid gland tumors needs adequate surgical treatment on the basis of knowledge of parotid gland anatomy and preoperative diagnosis.