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Choi Sooin,Hyun Jungwon,Yu HongBi,Cho Duck 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.5
Fatal ABO-incompatible (ABOi) transfusion is one of the most common causes of transfusion-related death, but its reporting has been limited in Korea. We comprehensively reviewed ABOi transfusion events in Korea by analyzing cases reported in literature, Korean hemovigilance system (KOHEVIS) annual reports, and written judgments. Written judgments were assessed using a written judgment management system or a comprehensive legal information system. We found nine cases of ABOi transfusion events in written judgments (from 1953 to 2019), 16 in the KOHEVIS (from 2008 to 2018), and nine in published reports (from 1978 to 2019). One case was found in all three sources. Overall, we found 32 cases of ABOi transfusion events. Four cases died and 23 survived, while the outcomes for five were unavailable. ABOi transfusion errors occurred at the administration (50%, 16/32), sample (13%, 4/32), and testing (9%, 3/32) stages. The causes of errors were unavailable for nine cases (28%, 9/32). We report the status of ABOi transfusions in Korea and expect our results to contribute to the prevention of adverse reactions due to ABOi transfusion.
Common Data Model-based Analysis of Selective Leukoreduction Protocol Compliance at Three Hospitals
Choi Sooin,Choi Soo Jeong,Shin Jeong Won,Yoon Young Ahn 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.2
Background: The selective leukoreduction protocol (SLP) is limited in that patients who require it can be overlooked. We estimated SLP compliance (SLPC) using the Observational Medical Outcomes Partnership common data model (CDM). Methods: Patients were classified into eight groups: pre- and post-hematology disease (A and B), pre- and post-solid organ transplantation (C and D), solid cancer (E), immunodeficiency (F), anticancer therapy (G), and cardiovascular surgery (H). We examined the red blood cell (RBC) transfusion history from three hospital datasets comprising approximately three million patients over 20 years using CDM-based analysis. SLPC was calculated as the percentage of patients who received only leukoreduced RBCs in total patients transfused RBCs. Results: In total, 166,641 patients from three hospitals were enrolled in this study. From 2001 to 2021, SLPC in all groups, except H, tended to increase, although there were differences among the hospitals. Based on the most recent values (2017–2021), the SLPC in groups A, B, D, and G was maintained at ≥75% until 1,095 days before or after diagnosis or treatment. Groups E, F, and H had < 50% SLPC one day after diagnosis and treatment. Conclusions: CDM analysis supports the review of large datasets for SLPC evaluation. Although SLPC tended to improve in most patient groups, additional education and monitoring are needed for groups that continue to show low SLPC.
Rotor Blade Sweep Effect on the Performance of a Small Axial Supersonic Impulse Turbine
Sooin Jeong,Byoungik Choi,Kuisoon Kim 한국항공우주학회 2015 International Journal of Aeronautical and Space Sc Vol.16 No.4
In this paper, a computational study was conducted in order to investigate the rotor blade sweep effect on the aerodynamics of a small axial supersonic impulse turbine stage. For this purpose, three-dimensional unsteady RANS simulations have been performed with three different rotor blade sweep angles (-15°, 0°, +15°) and the results were compared with each other. Both NTG (No tip gap) and WTG (With tip gap) models were applied to examine the effect on tip leakage flow. As a result of the simulation, the positive sweep model (+15°) showed better performance in relative flow angle, Mach number distribution, entropy rise, and tip leakage mass flow rate compared with no sweep model. With the blade static pressure distribution result, the positive sweep model showed that hub and tip loading was increased and midspan loading was reduced compared with no sweep model while the negative sweep model (-15°) showed the opposite result. The positive sweep model also showed a good aerodynamic performance around the hub region compared with other models. Overall, the positive sweep angle enhanced the turbine efficiency.
Quasieigenstate Coalescence in an Atom-Cavity Quantum Composite
Choi, Youngwoon,Kang, Sungsam,Lim, Sooin,Kim, Wookrae,Kim, Jung-Ryul,Lee, Jai-Hyung,An, Kyungwon American Physical Society 2010 Physical Review Letters Vol.104 No.15
<P>We report the first direct observation of an exceptional point (EP) in an open quantum composite of a single atom and a high-Q cavity mode. The atom-cavity coupling constant was made a continuous variable by utilizing the multisublevel nature of a single rubidium atom when it is optimally coupled to the cavity mode. The spectroscopic properties of quasieigenstates of the atom-cavity composite were experimentally investigated near the EP. Branch-point singularity of quasieigenenergies was observed and its 4pi symmetry was demonstrated. Consequently, the cavity transmission at the quasieigenstate was observed to exhibit a critical behavior at the EP.</P>