Algorithms for finding the minimal polynomials and inverses of resultant matrices

Shu-Ping Gao,San-Yang Liu 한국전산응용수학회 2004 Journal of applied mathematics & informatics Vol.16 No.-

In this paper, algorithms for computing the minimal polynomial and the common minimal polynomial of resultant matrices over any field are presented by means of the approach for the Gr¨obner basis of the ideal in the polynomial ring, respectively, and two algorithms for finding the inverses of such matrices are also presented. Finally, an algorithm for the inverse of partitioned matrix with resultant blocks over any field is given, which can be realized by CoCoA 4.0, an algebraic system over the field of rational numbers or the field of residue classes of modulo prime number. We get examples showing the effectiveness of the algorithms.

The Effects of Spaceflight on Soluble Protein, Isoperoxidase, and Genomic DNA in Ural Licorice (Glycyrrhiza uralensis Fisch.)

Gao, Wen-Yuan,Fu, Rong-Zhao,Fan, Lei,Zhao, Shu-Ping,Paek, Kee-Yoeup 한국식물학회 2000 Journal of Plant Biology Vol.43 No.2

We investigated the effects of weightlessness, and ionizing radiation plus weightlessness, on changes in the levels of soluble protein, isoperoxidase, and genomic DNA, respectively, in a medicinal plant-ural licorice (Glycyrrhiza uralen-sis)-after a 15-d spaceflight in a recoverable satellite. Both the weightlessness samples (Ws) and the ionizing radiation plus weightlessness samples (IR/Ws) showed increases in soluble protein content or peroxidase activity, compared with the ground control (Gc). Moreover, the increased isoperoxidase activity for the IR/Ws group was significantly greater than for the Ws, compared with the controls. Likewise, distinctive RAPD profiles were generated among the Ws, the IR/Ws, and the Gc. The Ws and IR/Ws yielded 66 and 78 polymorphic RAPD fragments, respectively, based on bulk template DNA, along with 19 selected primers. Therefore, weightlessness alone can trigger genomic alterations, to some extent, and may even result in modulation of gene expression, whereas ionizing radiation would probably enhance the effect of weightlessness.

Spaceflight of Platycodon grandiflorum Seeds Changes Ultrastructure of Pedicel and Style Cells

Wen-Yuan Gao(高文遠),Lei Fan(范磊),Kee-Yoeup Paek(白基燁),Shu-Ping Zhao(趙淑萍) 한국원예학회 2000 Horticulture, Environment, and Biotechnology Vol.41 No.6

Efficacy and safety of olmesartan medoxomil/amlodipine fixed-dose combination for hypertensive patients uncontrolled with monotherapy

Jun-Ren Zhu,Shu-Yang Zhang,Ping-Jin Gao 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.12

This study aimed to evaluate the efficacy andsafety of olmesartan medoxomil (OM)/amlodipine (AML)20/5 mg fixed-dose combination tablet in Chinese mild tomoderately hypertensive patients with inadequate bloodpressure (BP) control on monotherapy. Two multicenter,randomized, double-blind, double-dummy, active-controlled,parallel group clinical trials were conducted. Afterscreening and a 2-week placebo run-in period, patients with95 mmHg B seated diastolic blood pressure (SeDBP) \110 mmHg received monotherapy with OM 20 mg (inStudy 1) or AML 5 mg (in Study 2), once daily for4 weeks. Patients with 90 mmHg B mean SeDBP \110 mmHg at the end of the monotherapy period wererandomized to receive OM/AML 20/5 mg treatment orcontinue with the monotherapy, once daily for 8 weeks. OM/AML (20/5 mg) treatment significantly lowered bothsystolic and diastolic BP at 4 and 8 weeks compared to40 mg olmesartan or 5 mg AML. The incidence of drugrelatedadverse effects did not differ significantly betweenthe groups. OM/AML 20/5 mg was superior to OM 40 mgor AML 5 mg monotherapy in lowering BP in Chinesemild to moderately hypertensive patients with inadequateBP control on monotherapy. No new or unexpected safetyissues were identified with OM/AML combination therapycompared to monotherapy.

Distributed Dual-rate Consensus Predictive Control of Looper Tension System in Hot Rolling Mills

Xiao-Dong Zhang,Shao-Shu Gao,Xin-Ping Liu,Ting-Pei Huang 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.2

This paper considers a dual-rate distributed predictive control strategy for the looper tension system in hot rolling mills, which is a typical multi-agent system with directed communication topology. First, we establish an interconnected model for looper tension control system and the disturbances from the neighbors are considered effectively. Second, the consensus control protocol is developed based on the proposed control strategy to improve the robustness and stability of the multi-agent, and the sufficient conditions for consensus are developed. We update and implement all the agent controllers sequentially in one output sampling period and begin a new cycle at the next sampling instant, which leads the multi-agent control system is of fast control updating rate and slow output sampling rate. The control inputs of neighbors can be obtained to compensate the coupling effects, and the cooperation of controllers are improved. Finally, simulation results verify the proposed control strategy and corresponding results.

Use of Clozapine for the Treatment of Schizophrenia: Findings of the 2006 Research on the China Psychotropic Prescription Studies

Tian-Mei Si,Yun-shu Zhang,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Cheng,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2012 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.10 No.2

Objective: Clozapine is one of the most commonly used antipsychotic drugs in China. To date, few studies have investigated the patterns the prescription of clozapine nationwide. The present study examined these patterns in China in 2006 and identified the demographic and clinical characteristics associated with the use of clozapine. Methods: Using a standardized protocol and data collection procedure, we surveyed 5,898 patients with schizophrenia in 10provinces with differing levels of economic development. Results: Overall, clozapine had been prescribed for 31.9% (n=1,883) of the patients; however we found considerable variation among the 10 provinces. The frequency of clozapine use was highest in Sichuan (39.3%) and lowest in Beijing (17.3%). The mean daily dose of clozapine was 210.36±128.72 mg/day, and 25.1% of the patients were treated with clozapine in combination with other antipsychotics. Compared with the group not receiving clozapine, clozapine-user had been treated for longer durations and had experienced a greater number of relapses and hospitalizations. Furthermore, those in the clozapine-user had lower family incomes, were less able to seek psychiatric services, and more likely to be male and have a positive family history of schizophrenia. A multiple logistic regression analysis revealed that age, sex, professional help-seeking behaviors, duration of illness, economic status, educational level, and clinical manifestations were associated with the use of clozapine. Conclusion: Clozapine use is common in China. However, use of the antipsychotic varies among provinces, and demographic and clinical factors play important roles in the prescription of clozapine.

Influence of fracture characters on flow distribution under different Reynold numbers

Wang, Jing,Li, Shu-Cai,Li, Li-Ping,Gao, Cheng-Lu Techno-Press 2018 Geomechanics & engineering Vol.14 No.2

Water inrush through the destruction of water resisting rock mass structure was divided into direct water inrush, key block water inrush and splitting water inrush. In the direct water inrush, the Reynolds numbers has a significant effect on the distribution of the water flow and vortex occurred in the large Reynolds numbers. The permeability coefficient of the fracture is much larger than the rock, and the difference is between 104 and 107 times. The traditional theory and methods are not considering the effect of inertia force. In the position of the cross fracture, the distribution of water flow can only be linearly distributed according to the fracture opening degree. With the increase of Reynolds number, the relationship between water flow distribution and fracture opening is studied by Semtex.

Factors that Influence the Presciption of Antipsychotics for Patients with Schizophrenia in China

Tian-Mei Si,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Chen,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2011 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.9 No.3

Objective: To investigate the patterns of antipsychotic use in China and to analyze the factors that influence antipsychotic prescriptions. Methods: A standardized survey was conducted from May 20 to 24 2002 in five different regions of China with varying economic levels. The patterns of antipsychotic medication use were analyzed in a sample of 4,779 patients with schizophrenia. The survey gathered information on demographic characteristics, clinical profiles, and antipsychotic medications prescribed. Multiple logistic regression was used to analyze factors related to patterns of antipsychotic medication use. Results: A plurality of patients with schizophrenia was treated with clozapine (39%); this was followed by risperidone, sulpride,chlorpromazine, perphenazine, and haloperidol. More than 56.3% of patients were treated with only one atypical antipsychotic. The mean daily dose of chlorpromazine was 365±253 mg (mean±standard deviation), and 6.5% of patients were treated with depot injections of typical antipsychotic medications. A total of 73.7% (n=3,523) of patients with schizophrenia received monotherapy,24.8% (n=1,183) received two antipsychotics, 1.1% (n=52) received three antipsychotics, and one received four different antipsychotics. Patients often simultaneously received other classes of medications including anticholinergic agents, benzodiazepines,β-blockers, antidepressants, and mood stabilizers. Economic status and clinical symptoms were the main factors that contributed to the patterns of antipsychotic prescription. Conclusion: The present study suggests that atypical antipsychotic medications, especially clozapine, are the primary psychiatric treatments of choice in the management of schizophrenia in China. Moreover, the economic status and clinical profile of the patient are the major factors affecting the prescription of antipsychotic medication.

Effects of irradiation treatment on protein structure and digestion characteristics of seed-watermelon (Citrullus lanatus var.) kernel protein

Zhi-hao Li,Shang Chu,Ping Wang,Sihai Gao,Shu-gang Li,Xiongwei Yu 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.9

This study examined the effects of differentdoses of irradiation treatments on protein structure anddigestion characteristic of seed-watermelon seed kernelprotein. The results showed that, the molecular structure ofseed-watermelon kernel protein was unfolded after theirradiation treatment, the content of b-sheet structure in thesecondary structure was decreased, while the content ofrandom coil structure increased. The average particle sizeof the protein increased, and the hydrophobic group buriedin the b-sheet structure was exposed hence the surfacehydrophobicity increased. Besides, the surface morphologyof seed-watermelon protein changed from smooth and flatto coarse and concave, the specific surface area in contactwith the aqueous medium increased and its solubilityincreased, the distribution of peptides in the digestabecame wider, and the small molecular weight peptidesgradually increased.

MLH1 Polymorphisms and Cancer risk: a Meta-analysis Based on 33 Case-control Studies

Xu, Jia-Li,Yin, Zhi-Qiang,Huang, Ming-De,Wang, Xie-Feng,Gao, Wen,Liu, Ling-Xiang,Wang, Rong-Sheng,Huang, Pu-Wen,Yin, Yong-Mei,Liu, Ping,Shu, Yong-Qian Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

Objective: Cumulative evidence suggests that MLH1, the key component in the mismatch pathway, plays an important role in human cancers. Two potential functional polymorphisms (-93G>A and I219V) of MLH1 have been implicated in cancer risk. The aim of this meta-analysis was to summarize the evidence for associations. Methods: Eligible studies were identified by searching the electronic literature PubMed, ScienceDirect and Embase databases for relevant reports and bibliographies. Studies were included if of case-control design investigating MLH1 polymorphisms (-93G>A and I219V) and cancer risk with sufficient raw data for analysis. Odds ratios (OR) and 95% confidence intervals (95% CI) were used to evaluate the strength of associations. Results: Our meta-analysis from 33 published case-control studies showed the variant A allele of -93G>A polymorphism to be associated with increased risk in all genetic models (AA vs. GG: OR = 1.22, 95% CI: 1.03-1.44), especially among non-Asians (AA vs. GG: OR = 1.28, 95% CI: 1.04-1.58). For the I219V polymorphism, however, there was no main effect associated with overall cancer risk in any genetic model. Conclusions: The meta-analysis suggested that the MLH1 -93G>A polymorphism may be a biomarker of cancer susceptibility. Large sample association studies and assessment of gene-to-gene as well as gene-to-environment interactions are required to confirm these findings.