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Kazuya Shinmura,Hideki Murakami,Satoru Demura,Satoshi Kato,Katsuhito Yoshioka,Hiroyuki Hayashi,Noriaki Yokogawa,Takashi Igarashi,Moriyuki Fujii,Noritaka Yonezawa,Hiroyuki Tsuchiya 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.6
Study Design: A retrospective study. Purpose: To evaluate the immunity-enhancing effect of implantation of a liquid nitrogen-treated tumor. Overview of Literature: We have developed a new technique of implanting a tumor frozen in liquid nitrogen after posterior decompression and stabilization, with the aim of enhancing antitumor immunity in order to prolong the survival period of the patient. In the current study, the immunity-enhancing effect of this new technique has been evaluated. Methods: The subjects were 19 patients in whom we had earlier performed decompression and stabilization between April 2011 and September 2013. The 19 subjects were divided into two groups, namely a frozen autologous tumor tissue implantation group (n=15; “implantation group”), which consisted of patients, who underwent implantation with autologous tumor tissue frozen in liquid nitrogen, and a control group (n=4), which consisted of patients, who did not undergo autologous cancer transplantation. To evaluate the immunity-enhancing effect of the protocol, plasma cytokines (interferon [IFN]-γ and interleukin [IL]-12) were analyzed before surgery and a month after surgery. Results: The mean rate of increase in IFN-γ was significantly higher in the implantation group (p =0.03). Regarding IL-12, no significant difference was observed between the groups, although the implantation group exhibited increased levels of IL-12 (p =0.22). Conclusions: Decompression and stabilization combined with autologous frozen tumor cell implantation can enhance cancer immunity in metastatic spinal tumor patients. It is hypothesized that this procedure might prevent local recurrence and prolong survival period.
자기연마법에 의한 파인세라믹 Bar의 가공특성에 관한 연구
문상돈,Takeo Shinmura,Hitomi Yamaguchi,Toshio Aizawa,조철용 한국공작기계학회 2006 한국공작기계학회 추계학술대회논문집 Vol.2006 No.-
In this paper, the possibility of high precision machining was confirmed by using magnetic abrasive finishing process with rotating fine ceramic bar in high speed. Also, in order to improve the surface roughness, it was used the vibration of the magnetic pole and the mixed grain which is mixed with diamond paste for ultra precision processing and electrolytic iron powder. As a result, we knew that there is closely connected with diamond grain size, change of quantity and vibration of the magnetic pole to surface roughness of ceramic bar.
자기 연마법에 의한 질화 규소계 세라믹 파이프 내면의 경면 연마 특성에 관한 연구
박원규,타케오시무라,Park, Won-Gyu,Shinmura, Takeo 대한기계학회 2001 大韓機械學會論文集A Vol.25 No.1
Results ar presented of a new process for internal precision finishing of slender fine ceramic pipes using a magnetic field generated by a permanent magnets. For finishing the interior surface of a long pipe, a new type of finishing equipment was developed which can be very easily used in an industrial surrounding. In general, the pipe is so slender that a conventional finishing tool is hardly inserted into the pipe deeply, being impossible to finish. Therefore, a new technology has been considered to finish inside of a slender ceramic pipe by a simple technique. In this experimental, Magnetic Abrasive Machining is applied for the inner surface of silicon nitride fine ceramic pipe using ferromagnetic particles mixed with chromium-oxide powder. It is shown the initial roughness of 2.6㎛ Ry(0.42㎛ Ra) in the inside surface can be precisely finished to the roughness of 0.1㎛ Ry(0.01㎛ Ra). This paper discusses the outline of the processing by the application of magnetic abrasive machining and a few finishing characteristics.
자기연마법에 의한 파인세라믹 Bar의 가공특성에 관한 연구
문상돈(Sang-Don Mun),Takeo Shinmura,Hitomi Yamaguchi,Toshio Aizawa,조철용(Chul-Yong Cho) 한국생산제조학회 2006 한국공작기계학회 춘계학술대회논문집 Vol.2006 No.-
In this paper, the possibility of high precision machining was confirmed by using magnetic abrasive finishing process with rotating fine ceramic bar in high speed. Also, in order to improve the surface roughness, it was used the vibration of the magnetic pole and the mixed grain which is mixed with diamond paste for ultra precision processing and electrolytic iron powder. As a result, we knew that there is closely connected with diamond grain size, change of quantity and vibration of the magnetic pole to surface roughness of ceramic bar.
자기연마법에 의한 파인 세라믹 BAR의 가공특성에 관한 연구
문상돈 ( Sang-don Mun ),( Takeo Shinmura ),( Hitomi Yamaguchi ),( Toshio Aizawa ),조철용 ( Chul-yong Cho ) 한국환경기술학회 2006 한국환경기술학회지 Vol.7 No.3
본 논문에서는 파인 세라믹 바를 고속으로 회전시켜 자기연마법을 이용하여 고정밀가공의 가능성을 확인하였다. 또한 표면 정밀도를 향상시키기 위해 전해철분과 초정밀 가공용 다이아몬드 입자를 혼합한 지립과 자극의 진동을 이용하였다. 결과적으로 다이아몬드의 입자 크기, 양의 변화 그리고 자극의 진동과 세라믹 바의 표면거칠기가 밀접하게 관련되어 있다는 것을 알 수 있었다. In this paper, the possibility of high precision machining was confirmed by using magnetic abrasive machining with rotating fine ceramic bar in high speed. Also, in order to improve the surface roughness, it was used the vibration of the magnetic pole and the mixed grain which is mixed with diamond paste for ultra precision machining and electrolytic iron powder. As a result, we knew that there is closely connected with diamond grain size, change of quantity and vibration of the magnetic pole to surface roughness of ceramic bar.
Satoshi Kato,Satoru Demura,Yuki Kurokawa,Naoki Takahashi,Kazuya Shinmura,Noriaki Yokogawa,Noritaka Yonezawa,Takaki Shimizu,Ryo Kitagawa,Hiroyuki Tsuchiya 대한재활의학회 2020 Annals of Rehabilitation Medicine Vol.44 No.3
Objective To examine the efficacy and safety of an innovative, device-driven abdominal trunk muscle strengthening program, with the ability to measure muscle strength, to treat chronic low back pain (LBP) in elderly participants. Methods Seven women with non-specific chronic LBP, lasting at least 3 months, were enrolled and treated with the prescribed exercise regimen. Patients participated in a 12-week device-driven exercise program which included abdominal trunk muscle strengthening and 4 types of stretches for the trunk and lower extremities. Primary outcomes were adverse events associated with the exercise program, improvement in abdominal trunk muscle strength, as measured by the device, and improvement in the numerical rating scale (NRS) scores of LBP with the exercise. Secondary outcomes were improvement in the Roland-Morris Disability Questionnaire (RDQ) score and the results of the locomotive syndrome risk test, including the stand-up and two-step tests. Results There were no reports of increased back pain or new-onset abdominal pain or discomfort during or after the device-driven exercise program. The mean abdominal trunk muscle strength, NRS, RDQ scores, and the stand-up and two-step test scores were significantly improved at the end of the trial compared to baseline. Conclusion No participants experienced adverse events during the 12-week strengthening program, which involved the use of our device and stretching, indicating the program was safe. Further, the program significantly improved various measures of LBP and physical function in elderly participants.