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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • KCI등재후보
      • SCOPUSKCI등재
      • 乾畓直播畓과 湛水直播畓의 土壤物理性 變化에 따른 用水量 및 合理的 管理體系에 관한 硏究

        金始源 건국대학교 1977 學術誌 Vol.21 No.2

        Direct seeding culture of paddy rice on upland field is one of the most productive laborsaving cultivation of rice. The present study was conducted to clarify the relationship between percolation loss, and growth and yield of rice in the direct seeding cultures on upland and submersed Held. The results were as follows : 1) The percolation loss in the upland condition was 16.8 mm per day and in the submerged, it was 12.5mm per day. However the total water requirement on the upland was 462,5 mm and that of the submerged was 829.3mm which was 79.3% more than the water requirement in the direct seeding culture on the upland field. 2) The growth of rice on the submerged field was greater than that of the upland. The end of tillering stage appeared about at the end of July on the submerged field. It appeared at the beginning of August on the upland field. 3) Stem height, spike length, grain weight and straw weight in the direct seeding on the upland field were less than those on the submerged. On the other hand, grain number per ear and thousand-grain-weight on the upland field were greater than those on the submerged. 4) Deeper-plowing-plot resulted better growth and yield of rice than the control plot.

      • 우리 나라 自然洞窟의 地理的 分布와 그 特性에 관한 硏究

        洪始煥 건국대학교 1976 學術誌 Vol.20 No.2

        Many Natural Caves are spreaded over the our country. In old times, the forefathers made use of them for the house, the shelter, a place of the discipline, and the military base. At large these caves are divided into the three classes. They are limestone cave, Lava tunnel and sea erosional cave. Limestone cave are spreaded over the area of Sam-Chuck, Young-Wol, Pyong-Chang, Jeong-Seon in Kang Won Do, and Dan-Yang in Chung-Cheong Buk-Do and Ull-Jin in Kyong-sang Buk-Do, Lava tunnel is distributed to Che-Ju Island. We can discover sea erosional cave in the souther coast region. The caves witch are famous for limestone cave are Song-Ryu cave in Ull-Jin. Go-Si cave and Yong-Dam cave in Young-Wol, Hwa-Am cave in Jeong-seon, Go-Su cave and On-Dal cave in Dan Yang, Cheon-Ho cave in It-San, Yeong-Jae cave in Hwa-sun and Gim-Nyeon cave, Man-fang cave, Bilemok cave, Hyeb-Jae cave in Che-Ju Island. Most of them are develop for the tourist exploitation. Go-Si cave is famous for the rare creature. Then all of our limestone eave are distributed to the region of limestone cave. Most of them belong to Ordovician period. Their development was established in ancient time. Among Speleothem of the cave in our country particulary, stractite and stalagmite advanced on a large scale, and a lot of colum are immence. The other hand, the entrance of Lava tunnel in Che-Ju Island have anything peculiar which was built when the ceiling was sink. Then our caves have a great value of academic by the reason of the geographical spectacle. The character of creature in the cave will be a great help to the academic study. In addition, the cave which has a profitable condition in the tourist exploitation issuspected to develop in future.

      • 소아기 외상성 경막외혈종 환자에서의 보존적 치료

        송시헌 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

        With the advent of computerized tomography(CT) , an increasing number of patients with only minimal symptoms and signs are found to harbor considerable amount of acute epidural hematomas. Although most of these patients were still subjected to craniotomy because of the neurosurgeon's ingrained fear of delayed deterioration, the initial stable status of these patients warrants some rethinking about conservative treatment. The purpose of this study was to present a 34 pediatric epidural hematoma patients who were treated conservatively at Chungnam National University Hospital over a recent 6 year period and to define the clinical parameters that may aide in the conservative management of patients with epidural hematomas who were in state of clinically stable minimal symptoms and signs. Analysis of the patients revealed that age, sex, Glasgow Coma Scale score of more than 12, an initial size of the hematoma of less than 40cc, the presence of skull fracture and the hematoma locations are not risk factors for delayed deterioration. This study propose that those children with epidural hematoma who initially have a stable neurological status can be successfully selected for close observation and conservative treatment.

      • 소아 뇌종양의 임상적 고찰

        송시헌 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        Between January, 1983 and July, 1992, 41 children(aged 15 years or younger) with various types of brain tumors were managed at Chungnam National University Hospital. The results were as follows : 1. Among all the incidences of intracranial tumors, pediatric tumors were 15.1%. 2. The peak age was 6~10 (48.8%). 3. The most common pediatric brain tumor was astrocytoma (31.7%) and primitive neuroectodermal tumor (29.3%). 4. Supratentorial tumor (51.2%) were slightly higher than infratentorial tumors in frequency. 5. Headache and vomiting were the two most common presenting symptoms. 6. Infratentorial timors (85%) were more frequently associated with hydrocephalic change than supratentorial tumors (52.4%). 7. The treatment result was worse in patients with hydrocephalic change than those without. 8. The overall operative mortality (mortality within 1 month) was 7.4%.

      • 소아 중등도 두뇌손상환자에 대한 임상적 고찰

        송시헌,고현송 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        The authors review the records of 88 pediatric head injured patients whose initial Glasgow coma scale (GCS) scores ranged from 9 to 12 and who were treated at Chungnam National University Hospital over a recent 4-year period. These results are compared with reports from other centers and severely brain injured groups. The results were as follows : 1. The peak age group was between 6 and 8 years and were predominantly males (2.7 : 1 ratio). 2. The most common cause of head injury was as a pedestrian in a motor vehicle accident (72.7% ). 3. The number of patients with abnormalities on cranial computerized tomography (CT) and magnetic resonnance imaging (MRI) was 71 (80.7%) and the most common lesion was brain contusion (20/88). 4. The number of patients with intracranial hematoma was twenty-three (26%). 5. Twelve patients (13.6%) received cranial operation (four for hematoma removal and eight for repair and elevation of depressed fractures). 6. Eighty-three patients (94.3%) showed a good recovery, one patient (1.1%) died and four patients (4.5%) showed moderate or severe disability. 7. There was no relationship between age and intracranial lesions or GCS score and also there was no relationship between skull fracture and intracranial lesions or GCS score.

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