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A SSN-Reduced 5Gb/s Parallel Transmitter
Lee, Seon-Kyoo,Kim, Young-Sang,Park, Hong-June,Sim, Jae-Yoon The Institute of Electronics and Information Engin 2007 Journal of semiconductor technology and science Vol.7 No.4
A current-balancing segmented group-inverting transmitter is presented for multi-Gb/s single-ended parallel links. With an additional increase of 4 pins, 16-bit data is efficiently encoded to 20 pins to achieve the current balancing and eliminate the simultaneous switching noise. Since the proposed coding is a simple inversion-or-not transformation of pre-defined groups of binary data, it can be implemented with simplified logic circuits. The transmitter is designed with a $0.18{\mu}m$ CMOS technology, and simulated eye diagrams at 5Gb/s show dramatic improvements in signal integrity.
A SSN-Reduced 5Gb/s Parallel Transmitter
Seon-Kyoo Lee,Young-Sang Kim,Hong-June Park,Jae-Yoon Sim 대한전자공학회 2007 Journal of semiconductor technology and science Vol.7 No.4
A current-balancing segmented groupinverting transmitter is presented for multi-Gb/s single-ended parallel links. With an additional increase of 4 pins, 16-bit data is efficiently encoded to 20 pins to achieve the current balancing and eliminate the simultaneous switching noise. Since the proposed coding is a simple inversion-or-not transformation of pre-defined groups of binary data, it can be implemented with simplified logic circuits. The transmitter is designed with a 0.18μm CMOS technology, and simulated eye diagrams at 5Gb/s show dramatic improvements in signal integrity.
Seon-Kyoo Lee,Byungsub Kim,Hong-June Park,Jae-Yoon Sim IEEE 2013 IEEE transactions on circuits and systems. a publi Vol.60 No.2
<P>This brief presents an 8-bit parallel transceiver for low-power memory interface with a current-regulated voltage-mode driver and a clock and data recovery performing both bit recovery and byte alignment. Sharing a current source by output drivers enables voltage swing control without any regulator circuit while holding the benefits of low-power voltage-mode driving. In the receiver, with only one phase rotator in a globally shared phase-locked loop, a narrow-range delay line in each deskewing phase recovery loop effectively performs seamless phase adjustment. The transceiver, implemented in a 90-nm CMOS, shows a data rate of 6 Gbit/s/ch with a bit error rate of 10<SUP>-12</SUP> and a power consumption of 2.8 mW/Gbit/s.</P>
A 1 GHz ADPLL With a 1.25 ps Minimum-Resolution Sub-Exponent TDC in 0.18 <tex> $\mu$</tex> m CMOS
Seon-Kyoo Lee,Young-Hun Seo,Hong-June Park,Jae-Yoon Sim IEEE 2010 IEEE journal of solid-state circuits Vol.45 No.12
<P>An all-digital PLL for wireline applications is designed with a sub-exponent TDC which adaptively scales its resolution according to input time difference. By cascading 2× time amplifiers, the TDC efficiently generates the exponent-only information for fractional time difference. To improve linearity in a wide input range, a replica-based self-calibration scheme is applied to the time amplifier. The TDC, implemented in a 0.18 μm CMOS, shows the minimum resolution of 1.25 ps with a total conversion range of 2.5 ns, the maximum operating frequency of 250 MHz, and power consumption of 1.8 mW at 60 MHz. The measured rms jitter of PLL was 5.03 ps at 960 MHz.</P>
A 5 Gb/s Single-Ended Parallel Receiver With Adaptive Crosstalk-Induced Jitter Cancellation
Seon-Kyoo Lee,Byungsub Kim,Hong-June Park,Jae-Yoon Sim IEEE 2013 IEEE journal of solid-state circuits Vol.48 No.9
<P>This paper presents an adaptive far-end crosstalk cancellation scheme for a single-ended parallel receiver. The adaptation engine is embedded in a single representative channel CDR, and the receiver efficiently reduces the crosstalk noise with a minimal cost in hardware and power consumption. In addition, the proposed scheme can be applied to any given CDR and equalizing circuits. The receiver is fabricated in 0.13 μm CMOS technology and achieves a reduction of FEXT-induced jitter up to 75%. The receiver consumes 65 mW at 5 Gb/s (4.3 mW/Gb/s/pin) including a PLL for global clock distribution.</P>
The Outcomes of Hypertransfusion in Major ABO Incompatible Allogeneic Stem Cell Transplantation
Lee Se Hoon,Park Joon Oh,Jung Chul Won,Park Keunchil,Lee Kyoo Hyung,Lee Mark Hong,Lee Kyung Eun,Park Jinny,Kim Kihyun,Kim Won Seog,Im Young Hyuk,Kang Won Ki,Kim Seon Woo,Lee Je Hwan,Park Se Hoon 대한의학회 2004 Journal of Korean medical science Vol.19 No.1
Uniconazol처리로 誘起된 옥수수 遺傳子 ZmKT4과 ZmKT28의 cloning 및 sequencing
Kwon Kyoo Kang(姜權圭),Ill Sup Nau(盧一燮),Hyo Yeon Lee(李孝淵),Young Il Lee(李榮日),Seon Ha Lee(李善河),Kameya Toshiaki(龜谷壽昭) 한국육종학회 1995 한국육종학회지 Vol.27 No.1
The seedling obtained from uniconazol treatment showed dwarfism and tillering. In order to identify uniconazol-induced genes, cDNA hybridization probes were made from poly(A⁺) RNA isolated from uniconazol-treated seedlings and untreated inbred line seedling(IK), and the putatively regulated clones was detected by the differential screening of the cDNA libray. RNA hybridization experiment revealed that two of the clones were in fact induced by application of uniconazol. mRNAs of ca. 800 and 1,500 baseds was identified by isolated two clones (ZmKT4 and ZmKT28) and markedly increased from 48hr after uniconazol application. ZmKT4 clones showed the highest level of mRNA accumulation in tassels, ears and leaves, and the lowest level in roots. ZmKT28 clone is expressed in the stems, tassels, silks, ears and leaves but no transcripts was detected in roots. Two clone may be associated wit the cell elongation and phase of vegetative growth.
Geun Young Lee,Sung Yu,Hyun Gu Kang,Jin Seon Kim,Kyoo Won Lee,Jung-Ho Lee 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2
Purpose: To assess choroidal thickness (CT) variation according to refractive errors using enhanced-depth imaging optical coherence tomography. Methods: Eighty-nine eyes (in 89 children) <±6 diopter were categorized into three groups: hyperopia, emmetropia, and myopia, according to refractive error, and underwent choroidal scans using enhanced-depth imaging-optical coherence tomography. CT was measured at the fovea and at 1 mm and 3 mm nasal (N1 and N3), temporal (T1 and T3), superior (S1 and S3), and inferior (I1 and I3) from the fovea. Results: Mean foveal CTs were 346.86 μm, 301.97 μm, and 267.46 μm in the hyperopia, emmetropia, and myopia groups, respectively (p < 0.05). CTs at N3 and T3 were 214.59 μm and 318.68 μm, 163.92 μm and 320.79 μm, and 153.93 μm and 295.61 μm in the hyperopia, emmetropia, and myopia groups, respectively (p < 0.05). All CTs in the hyperopia group were thicker than those of other groups (p < 0.05). Fovea was thickest and was significantly thicker than at N3 and I3 in hyperopia (p < 0.05). T3 thickness in the emmetropia and myopia groups was greater than thickness at other areas, particularly the nasal and inferior choroids (p < 0.05). CT was positively correlated with spherical equivalent (p = 0.029). Conclusions: In Korean children, CTs were greater in the hyperopia group than in the emmetropia and myopia groups. The temporal choroid was thicker than the nasal choroid, regardless of the refractive error. The thickest location in the hyperopia group was the fovea; however, the temporal choroid was thickest in the emmetropia and myopia groups.
인공 슬관절 전치환술을 받은 한국인에서 대퇴골 원위부 및 경골 근위부의 해부학적 특징
이건우(Geon Woo Lee),송은규(Eun-Kyoo Song),선종근(Jong-Keun Seon),이동현(Dong Hyun Lee),이태민(Tae Min Lee) 대한정형외과학회 2011 대한정형외과학회지 Vol.46 No.6
목적: 저자는 한국인의 대퇴골 원위부 및 경골 근위부의 해부학적 특징들을 분석하고, 남녀 간의 차이에 대하여 비교 분석하고자 하였다. 대상 및 방법: 슬관절 골관절염으로 ROBODOC<SUP>®</SUP>을 이용한 슬관절 전치환술을 시행받은 76명의 환자(여자: 50명, 남자: 26명)를 대상으로 하였으며, 대퇴골 원위부 및 경골 근위부의 해부학적 지표의 전후 길이 및 좌우 길이를 ORTHDOC program을 이용하여 측정하였다. 결과: 대퇴골 원위부 및 경골 근위부의 경우 한국 여성은 모든 해부학적 지표에서 남성에 비하여 작게 측정되었으며, 통계학적으로 유의한 차이를 보였다(모두 p<0.05). 하지만 전후 길이에 대한 좌우 길이의 비(Aspect ratio,%)의 경우 남녀 두 군 간에 대퇴골과 경골 모두에서 유의한 차이를 보이지는 않았다(모두>0.05). 결론: 한국인 여성에서 대퇴골 원위부 및 경골 근위부의 좌우 길이에 대한 전후 길이의 비율이 남성과 다르지 않고 대칭적으로 작은 형태를 가진다고 할 수 있겠다. Purpose: In this study, we examined the anatomic characteristics of the distal femur and the proximal tibia to determine if there were significant differences between male and female patients. Materials and Methods: Seventy six patients (50 of female, 26 of male) who were treated by total knee arthroplasty using ROBODOC<SUP>®</SUP>, were included. The anteroposterior and mediolateral length of the distal femur and proximal tibia were checked using the ORTHODOC program. Results: The mean sizes of the distal femur and proximal tibia of female knees were slightly smaller than those of male knees Statistically significant differences were observed between the two groups (p<0.05 for all). On the other hand, the anteroposterior and mediolateral ratios of distal femur and proximal tibia revealed no differences between female and male knees (p<0.05 for all) Conclusion: The anteroposterior to mediolateral ratio was similar in the distal femur and proximal tibia of Korean females.
Park, Jae Yeo,Jin, Dong-Hoon,Lee, Chang-Min,Jang, Min Ja,Lee, Sun Young,Shin, Hyo Seon,Chung, Yoon Hee,Kim, Kyung Yong,Kim, Sung Su,Lee, Won Bok,Shin, Yong Kyoo,Lee, Wang Jae,Park, Yeong-Min,Kim, Daej Lippincott Williams Wilkins, Inc. 2010 Journal of immunotherapy Vol.33 No.5
The requirement for CD4 T cells in priming and maintaining cytotoxic T-lymphocyte responses presents a long-standing paradox in cellular immunology. In this study, we used sequential coadministration of a DNA vaccine encoding an invariant (Ii) chain in which the class II-associated Ii-peptide region is replaced with CD4 T-helper epitope, PADRE [Pan human leukocyte antigen-DR reactive epitope (Ii-PADRE)] or Bcl-xL with a DNA vaccine encoding Sig/E7/LAMP-1 to verify the role of CD4 T cells for the generation of effectors and memory E7-specific CD8 T-cell immune responses. Sequential vaccination, with Ii-PADRE+Sig/E7/LAMP-1 priming followed by Bcl-xL+Sig/E7/LAMP-1 boosting led to generation of E7-specific CD8 T cells, and was nearly equivalent in effect to coadministration with Ii-PADRE+Sig/E7/LAMP-1 or Bcl-xL+Sig/E7/LAMP-1 at both prime and boost. The mice vaccinated with the Ii-PADRE+Sig/E7/LAMP-1 prime-Bcl-xL+Sig/E7/LAMP-1 boost regimen exhibited better long-term E7-specific immune responses and tumor prevention effects in vivo than the mice vaccinated with the reverse sequential coadministration. After CD4 T-cell depletion, mice primed with Ii-PADRE+Sig/E7/LAMP-1 generated low numbers of E7-specific CD8 T cells and suppressed long-term memory CD8 T-cell response regardless of the sequence or combination of DNA vaccines administered. Mice primed with Bcl-xL+Sig/E7/LAMP-1 only suppressed long-term memory CD8 T-cell response after depletion of CD4 T cells before priming. Our findings suggest that activated CD4 T cells at prime phase are important to generate the antigen-specific CD8 T-cell immune responses and CD4 T cells, which are naive or activated, play a role to maintain the long-term memory responses.