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Associations between air pollutant levels and medical care visits for atopic dermatitis
( Se Ha Park ),( Seul Ki Lee ),( Jeong Soo Kim ),( Ha Ryeong Ryu ),( Hee Joo Kim ),( Hyang Joon Park ),( Jin Ok Baek ),( Joo Young Roh ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: The prevalence of Atopic dermatitis (AD) is rising in most industrialized countries, and it causes increased burden and costs in public health systems. Over the past decades, studies for effects of air pollution to human health were conducted and revealed considerable evidences that air pollutants ca Objectives: To estimate the effect of air pollutants on hospital visits of AD in Incheon and analyse the associating factors Methods: The study subjects were any medical care visits for atopic dermatitis in 2012-2015, which were identified by national health insurance claims data in Incheon, Republic of Korea. Air pollutants considered in this study were obtained from the Ministry of Environment Results: When using the pollutant levels of the current day and cumulative models to day 7, higher PM10, O3, and SO<sub>2</sub> significantly increased the risk of medical care visits for atopic dermatitis. In contrast, NO<sub>2</sub> and CO showed an inverse association with medical care visits for atopic dermatitis. There were no remarkable differences across age, gender and insurance groups in the risk for medical visits for atopic dermatitis. Higher risks were shown in those with previous AD diagnosis (PM10 and SO<sub>2</sub>) and those with allergic rhinitis (PM10, O<sub>3</sub>, and SO<sub>2</sub>) Conclusion: This study suggests that exposure to PM10, O3 and SO2 increase the hospital visit of AD in short-term period. Significant variables are underlying disease such as AD and allergic rhinitis
( Se Ha Park ),( Seul Ki Lee ),( Jeong Soo Kim ),( Ha Ryeong Ryu ),( Hee Joo Kim ),( Hyang Joon Park ),( Jin Ok Baek ),( Joo Young Roh ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Although atopic dermatitis (AD) has been characterized by predominant Th2 cytokines, Th1 cells are also involved in AD pathogenesis. Objectives: This study was to identify in vitro cytokine milieu that can accurately reproduce the expression profile of genes important in AD. Methods: mRNA levels of CCL22, CCL17, IL5, IL13, FLG, and LOR were evaluated by qRT-PCR in skin samples from 6 AD patients, 12 healthy controls, and HaCaT cells cultured variously with Th1 (TNF-α, IFN-γ) and/or Th2 (IL-4) cytokines. Cytokine effects on HaCaT cell growth were examined by phase-contrast microscopy and WST-1 assay. Results: Cell viability was not altered by treatment with TNF-α, IFN-γ, or IL-4 alone, or by combination of TNF-α and IL-4. Expression of Th2 genes (CCL22, CCL17, IL5 and IL13) was increased in human AD skin lesions, while cornified cell envelop-related FLG and LOR were reduced. Interestingly, similar HaCaT cell gene expression profiles were observed when stimulated with Th1 cytokines, but not with IL-4, implying that Th1 stimulation is required to reproduce the AD-like features in HaCaT cells. Conclusion: Collectively, Th1 and Th2 cytokines do not seem to function dichotomously, and a complex inflammatory network drives AD-like changes. Further in vitro experiments using HaCaT cells to study AD-related genes would need stimulation with various cytokine combinations not limited to Th2 polarization for optimal gene expression.
Jeong, Min-Woong,Sohn, Chang-Bae,Kim, Su Hong,Park, Jong-Ik,Park, Se-Ryeong,Min, Jun-Sik Yeungnam University College of Medicine 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Coronary stent dislodgement during percutaneous coronary intervention, which occurs when the stent is passed through tortuous and calcified lesions, is not a rare complication. Without proper treatment, such as fixing with another stent in the coronary artery or removing the undeployed stent from the coronary artery or systemic artery system, this complication can cause serious problems. We experienced the unusual situation of a dismounted and dislodged coronary stent, in which retrograde retrieval to the radial artery was impossible during transradial coronary intervention. We report on use of a rendezvous and snare technique at the brachial artery level via femoral puncture, which resulted in resolution without surgery.
[P268] Toxic shock syndrome in a child presented with profuse diarrhea and palmoplantar erythema
( Se Ha Park ),( Seul Ki Lee ),( Jeong Soo Kim ),( Ha Ryeong Ryu ),( Hee Joo Kim ),( Hyang Joon Park ),( Jin Ok Baek ),( Joo Young Roh ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Toxic shock syndrome (TSS) is an acute, multi-system, toxin-mediated illness, often resulting in multi-organ failure. It occurs due to production of TSS Toxin-1 (TSST-1) by Staphylococcus aureus that induces a severe immunologically mediated inflammatory response affecting multiple organ systems. The diagnosis of TSS consists of clinical feature with high fever, hypotension, diffuse erythroderma, and desquamation together with three or more findings of renal or liver dysfunction, coagulopathy, gastrointestinal or central nervous system disorder Wereport a case of 6-year-old boy with bullae and erosive patch on both hand and feet who had watery diarrhea and fever. He had been suffered from profuse watery diarrhea for 10 days. Laboratory studies revealed acute renal failure, thrombocytopenia and anemia accompanied by prolonged prothrombin time. Histopathologicexamination revealed subcorneal separation with bacterial debris and exocytosis with epidermal spongiosis. Diagnosis of TSS was made based upon clinical and laboratory findings. He expired even after intensive care with antibiotic treatment due to multi-organ failure and sepsis. Prompt diagnosis and appropriate management of TSS are critical. This boy with TSS demonstrated the clinical manifestation of fever, profuse diarrhea and palmoplantar desquamation. Profuse watery diarrhea and desquamation of skin can be diagnostic clue of TSS.
담배연기와 담뱃잎 내 함유된 방사능 농도분석 및 위해도 평가
이세령(Se-Ryeong Lee),이상복(Sang-Bok Lee),김정윤(Jeong-Yoon Kim),김지민(Ji-Min Kim),방예진(Yei-jin Bang),이두석(Doo-Seok Lee),조형준(Hyung-Joon Jo),김성철(Sungchul Kim) 대한방사선과학회(구 대한방사선기술학회) 2021 방사선기술과학 Vol.44 No.5
In this study, radioactivity quantitative analysis was performed on radon contained in cigarette, and the effective dose was calculated using the result value to determine the amount of exposure caused by smoking. A total of 5 types of cigarettes were sampled. Cigarette smoke was collected by using activated carbon, and tobacco were measured by homogenizing for quantitative analysis. For each sample, Bi-214 and Pb-214 were subjected to gamma nuclide analysis to observe the uranium-based radioactive material contained in cigarette, and a measurement time of 30,000 seconds was set for the sample based on the results of previous studies. As a result of measuring the radioactivity of tobacco, a maximum of 0.715 Bq/kg was derived, and in the case of cigarette smoke measured using activated carbon, a maximum of 3.652 Bq/kg was derived. Using this measurement, the average effective dose to the lungs is 0.938 mSv/y, and it was found that there is a possibility of receiving exposure up to 1.099 mSv/y depending on the type of tobacco. It was found that the exposure dose due to cigarette occupies a large proportion of the annual effective dose limit for the general public. Therefore, more diverse studies on radioactive substances in cigarette are needed, and measures to monitor and reduce the incidental exposure to radon should be established.
저소득층 에너지효율개선사업 시행시 유전 알고리즘을 적용한 최적화 계획에 관한 연구
최세영(Choi, Se-Yeong),장예지(Jang, Ye-Ji),송화령(Song, Hwa-Ryeong),최정민(Choi, Jeong-Min) 대한건축학회 2018 대한건축학회 학술발표대회 논문집 Vol.38 No.2
The purpose of this study is to present the basic data that can be used for the optimal planning with genetic algorithm considering the support cost and gas energy consumption for heating by major unit improvement items such as insulation, windows, and infiltration in the energy efficiency improvement projects of low income housing. As a result, these findings in this study will contribute to the reduction of national greenhouse gas emissions as well as the improvement of the thermal comfort of low-income housing.
( Min-woong Jeong ),( Chang-bae Sohn ),( Su Hong Kim ),( Jong-ik Park ),( Se-ryeong Park ),( Jun-sik Min ) 영남대학교 의과대학 2016 Yeungnam University Journal of Medicine Vol.33 No.2
Coronary stent dislodgement during percutaneous coronary intervention, which occurs when the stent is passed through tortuous and calcified lesions, is not a rare complication. Without proper treatment, such as fixing with another stent in the coronary artery or removing the undeployed stent from the coronary artery or systemic artery system, this complication can cause serious problems. We experienced the unusual situation of a dismounted and dislodged coronary stent, in which retrograde retrieval to the radial artery was impossible during transradial coronary intervention. We report on use of a rendezvous and snare technique at the brachial artery level via femoral puncture, which resulted in resolution without surgery.
( Min Woong Jeong ),( Su Hong Kim ),( Chang Bae Sohn ),( Song Hee Oh ),( Se Ryeong Park ),( Jun Sik Min ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: In recent years, percutaneous transluminal angioplasty (PTA) has been preferred to surgery in elderly patients with PAD who are more prone to concomitant diseases. We report our experience with PTA via a bypass graft vessel to treat a case of total occlusion of both the superfi cial femoral arteries in a patient who additionally contracted Leriche syndrome due to an aorto-iliac occlusion after receiving a left axillo- bifemoral graft. Case: A 67-year-old man received a left axillo-bifemoral graft at another hospital for aorto-iliac occlusion (Leriche syndrome) 11 years ago. He was referred to the cardiovascular department because of bilateral claudication symptoms and blue toe syndrome that he developed after walking over 200 m (Rutherford category 2). He had no past medical history of diabetes mellitus, hypertension, or dyslipidemia, except for a 50 pack/year history of smoking. His physical examination revealed the absence of pulses below both the popliteal arteries. The ankle brachial index (ABI) scores while resting were 0. 53 and 0. 67, and the ABI scores while exercising were 0. 26 and 0. 35, on the right and left sides, respectively. Enhanced lower extremity computed tomography angiography(CTA) revealed a distinct left axillo-femoral bypass graft and a total obstructive lesion at both SFAs just below the anastomotic site of the bypass graft vessel and femoral arteries. We performed PTA of right superfi cial femoral artery via a left axillo-bifemoral graft vessel. The second PTA for left superfi cial femoral artery was performed 6 months later. After the second PTA, the follow-up ABI improved from 0. 68 to 0. 78, and the claudication of both legs had also improved. The patient showed rapid improvement in his symptoms and complained only of mild claudication (Rutherford category 1).