Ownership Structure and Firm Performance: Evidence from Pharmaceutical and Chemical Industry of Bangladesh

SOBHAN, Raihan Korea Distribution Science Association 2022 Asian journal of business environment Vol.12 No.4

Purpose: The main purpose of this study is to find out the impact of ownership structure on firm performance in the pharmaceutical and chemical industry of Bangladesh. Research design, data and methodology: The study has been conducted on 28 listed pharmaceutical and chemical companies from 2012 to 2020. Return on Assets (ROA) and Tobin's Q are selected as indicators of internal and market performance of the firms respectively whereas institutional ownership, directors' ownership and foreign ownership are selected as proxies of ownership structure. Panel analysis using random effects, lag method and time dummy method is used to analyse the relationship. Results: The study has found the existence of highly concentrated directors' ownership, a low percentage of institutional ownership and a very insignificant proportion of foreign ownership in the industry. The regression results show that directors' ownership has a positive and significant impact on firm performance, supporting the concept of agency theory. The study has also found a positive and significant impact of foreign ownership on firm performance. Unfortunately, the impact of institutional ownership is found to be insignificant. Conclusions: Directors' ownership and foreign ownership decreases agency cost that ultimately increases firm performance. However, the role of institutional investors is not significant enough to improve firm performance. It is suggested that institutional investors should be more active and involved in monitoring the activities of the organisations to improve performance.

Development of SWNTs based biosensor for the assessment of peanut allergen

Sobhan ABDUS,Junhyun OH,Jinyoung LEE 한국생물공학회 2016 한국생물공학회 학술대회 Vol.2016 No.10

Assessment of peanut allergen Ara h1 in processed foods using a SWCNTs-based nanobiosensor

Sobhan, Abdus,Oh, Jun-Hyun,Park, Mi-Kyung,Kim, Seung Wook,Park, Chulhwan,Lee, Jinyoung Informa UK (TaylorFrancis) 2018 Bioscience, biotechnology, and biochemistry Vol.82 No.7

<P>The goals of this research were to develop a rapid single-walled carbon nanotube (SWCNT)-based biosensor and to employ it to commercial food products for Ara h1 detection. The SWCNT-based biosensor was fabricated with SWCNTs immobilized with antibody (pAb) through hybridization of 1-pyrenebutanoic acid succinimidyl ester (1-PBASE) as a linker. The resistance difference (R) was calculated by measuring linear sweep voltammetry (LSV) using a potentiostat. Resistance values increased as the concentration of Ara h1 increased over the range of 1 to 10(5)ng/L. The specific binding of anti-Ara h1 pAb to antigen including Ara h1 was confirmed by both indirect ELISA kit and biosensor assay. The biosensor was exposed to extracts prepared from commercial processed food containing peanuts, or no peanuts, and could successfully distinguish the peanut containing foods. In addition, the application of present biosensor approach documented the precise detection of Ara h1 concentrations in commercially available peanut containing foods.</P>

Detection of Peanut Allergen Ara h 6 in Commercially Processed Foods using a Single-Walled Carbon Nanotube-Based Biosensor

Sobhan, Abdus,Oh, Jun-Hyun,Park, Mi-Kyung,Lee, Jinyoung Oxford University Press 2018 Journal of AOAC International Vol.101 No.5

<B>Abstract</B><P>Background: The peanut protein Arachis hypogaea (Ara h) 6 is one of the most serious food allergens that contributes to food-related, life-threatening problems worldwide. The extremely low allergic dose demands for more selective and rapid methods for detecting Ara h 6. Objective: The goal of this study was to develop a single-walled carbon nanotube (SWCNT)-based biosensor for the rapid detection of Ara h 6 in commercial food products. Methods: The detection principle of this biosensor was based on the binding of Ara h 6 to the anti-Ara h 6 antibody (pAb) through 1-pyrenibutanoic acid succinimidyl ester. The resistance difference (ΔR) was calculated via linear sweep voltammetry using a potentiostat. Results: The ΔR increased as the Ara h 6 concentrations increased above the range of 100-107 pg/L. A specificity analysis showed that the anti-Ara h 6 pAb selectively interacted with Ara h 6 molecules in the buffer solution (pH 7.4). Conclusions: This research proposes that an SWCNT-based biosensor in self-assembly with antibodies could be an effective tool for the rapid detection of allergen proteins in food. Highlights: The developed biosensor exhibited higher sensitivity and selectivity. Application studies resulted in precise Ara h 6 detection in peanut-containing processed food.</P>

Rapid Detection of Ara h2 Using Single Walled Carbon Nanotube Based Biosensor for Peanut Allergen Control

Sobhan, Abdus,Oh, Jun Hyun,Lee, Jin Young Trans Tech Publications 2018 Applied Mechanics and Materials Vol. No.

<P>Peanut protein Ara h2 is one of the serious food allergens contributing to the allergic reaction, causing the common reasons for food-related life threating problems over the world. The objective of this study is to develop single-walled carbon nanotubes (SWCNTs) based biosensor using 1-pyrenibutanoic acid succinimidyl ester (1-PBASE) as a linker for rapid detecting peanut allergen Ara h2 in foods. The detection principal of this biosensor was based upon the binding of Ara h2 to the anti-Ara h2 on the linker-modified SWCNTs connecting gold electrode in biosensor silicon template. The measurements of each step were achieved using linear sweep voltammetry (LSV) with a potentiostat for Ara h2 detection. The application of anti-Ara h2 as pAbs on linker immobilized SWCNTs surface increased the sensor resistance values. The developed biosensor showed significant resistance response with the increase in the concentration of Ara h2 from 0 to 1000 ng/mL. Indirect enzyme-linked immunosorbent assay (ELISA) was successfully applied to confirm the specificity of antibodies using 96-well microplates. Scanning electrone microscopy (SEM) confirmed the microstructure of SWCNTs. Sensor sensitivity and specificity were tested with different peanut allergens and the detection range (1-1000 ng/mL).</P>

Repairing cracked aluminum plates by aluminum patch using diffusion method

Sobhan Dehghanpour,Alireza Nezamabadi,Mohammad Mahdi Attar,Farzan Barati,Mehdi Tajdari 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.10

The aim of this work is to scrutinize the importance of diffusion bonding temperature, pressure and time on the repair of a cracked aluminum plate while the maximum tensile strength under a quasi-static loading has been investigated. The diffusion method was used to connect aluminum patches to repair the central and mode I cracks in thin aluminum plates. Here, the process of repairing cracked pieces made of aluminum or aluminum alloys involved a chemical and mechanical step to remove aluminum oxide and press the patch and piece under the temperature difference at a certain time. The repaired pieces underwent a quasi-static tensile loading while the maximum tolerable amount of force was obtained in different situations. Having assigned five temperatures, 300, 400, 500, 550 and 600 ° C, as well as four test times 30, 60, 120 and 180 min and five different pressures 10, 20, 50, 80 and 110 bar, we utilized fractional factorial design approach to perform 40 tests while there was seen a 10 mm initial crack in repaired samples . Experimental results showed that the optimum connection was resulted at 550 °C and the pressure of 80 bars within 120 min where the maximum force tolerated by the repaired vs. the unrepaired piece increased by 92 %. Therefore, having weighed the repair method using the diffusion bonding, we suggest that this type of the repair method can be a proper and cheap alternative to composite and adhesive patches.

Single walled carbon nanotube based biosensor for detection of peanut allergy-inducing protein ara h1

Abdus Sobhan,오준현,박미경,김승욱,박철환,이진영 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.1

Food allergies are global trending issues in the food industry. Peanut allergy is an especially serious problem with emerging allergen symptoms because peanuts are utilized worldwide as a processing food source. Arachis hypogaea 1 (Ara h1) is a main seed storage protein from peanut materials that derives allergic medical symptoms. In this study, a single-walled carbon nanotube (SWCNT)-based biosensor was developed to detect Ara h1. The developed biosensor utilizes an Ara h1 antibody as a receptor for the target material, SWCNTs as a signal transfer, and 1- pyrenebutanoic acid succinimidyl ester (1-PBSE) as a linker between the SWCNTs and the receptors. SWCNTs dramatically transferred the biological reaction between the antibody and the antigen into measurable signals of electrical responses. The sensor capacity of the developed SWCNT-based biosensor, including the limit of detection (LOD, 1 ng/ mL), the detection range (1-1,000 ng/mL), and the washing amounts (three times), was confirmed.

Ownership Structure and Firm Performance: Evidence from Pharmaceutical and Chemical Industry of Bangladesh

Raihan SOBHAN 한국유통과학회 2022 Asian Journal of Business Environment (AJBE) Vol.12 No.4

Purpose: The main purpose of this study is to find out the impact of ownership structure on firm performance in the pharmaceutical and chemical industry of Bangladesh. Research design, data and methodology: The study has been conducted on 28 listed pharmaceutical and chemical companies from 2012 to 2020. Return on Assets (ROA) and Tobin’s Q are selected as indicators of internal and market performance of the firms respectively whereas institutional ownership, directors’ ownership and foreign ownership are selected as proxies of ownership structure. Panel analysis using random effects, lag method and time dummy method is used to analyse the relationship. Results: The study has found the existence of highly concentrated directors’ ownership, a low percentage of institutional ownership and a very insignificant proportion of foreign ownership in the industry. The regression results show that directors’ ownership has a positive and significant impact on firm performance, supporting the concept of agency theory. The study has also found a positive and significant impact of foreign ownership on firm performance. Unfortunately, the impact of institutional ownership is found to be insignificant. Conclusions: Directors’ ownership and foreign ownership decreases agency cost that ultimately increases firm performance. However, the role of institutional investors is not significant enough to improve firm performance. It is suggested that institutional investors should be more active and involved in monitoring the activities of the organisations to improve performance.

A novel approach to measuring fluid saturation using X-ray computed tomography

Sheikhi Sobhan,Burukhin Alexander,Cheremisin Alexey 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.11

Digital rock analysis using X-ray computer tomography (CT scan) is an ongoing topic for studying the porous media in geothermal, natural gas, and petroleum industries. This study provides a novel approach to calculating fluid saturation in low permeability cores utilizing X-ray computed tomography. In the present study, synthetic low permeability cores were used to analyze two-phase saturation at atmospheric pressure and temperature. In the experiments, no dopant was used for visualizing different phases. As a novelty of the paper, PHREEQC geochemical software was employed to verify the saturation of X-ray CT scanning through modeling the geochemical reaction between aqueous and gaseous phases. This study presents a novel and reliable approach to verify the saturation of X-ray CT scan through geochemical modeling. The results of this study also prove that using the saturation of mass balance as the initial condition of the geochemical modeling leads to an excellent agreement between the saturation of CT scan and geochemical modeling. According to the results obtained, there is a 24% difference between gas saturation in CT scan and mass balance method, while such discrepancy is only 13% between gas saturation in CT scan and geochemical modeling.

Cleaning and Reuse of Single Walled Carbon Nanotube-Based Biosensor For biomaterial detection

Abdus SOBHAN,Jun-Hyun OH,Jinyoung LEE 한국생물공학회 2018 한국생물공학회 학술대회 Vol.2018 No.4