Effect of the reaction temperature on nanocrystallites MgAl2O4 spinel ceramic precursor

Rong-tao Wang,Ying Peng,Xiao-wei Fan,Jian-xin Li,Xiao-ping Liang 한양대학교 세라믹연구소 2009 Journal of Ceramic Processing Research Vol.10 No.6

Mg-Al hydrotalcite (Mg6Al2(OH)16CO3·4H2O), the precursor of MgAl2O4 spinel, has been synthesized via a coprecipitation method, using AlCl3·6H2O and MgCl2·6H2O as the raw materials, and NaOH and Na2CO3 as the precipitators. The effect of the reaction temperature, from 50℃ to 90℃, on the Mg-Al hydrotalcite nanocrystallites was analyzed. The nanocrystallites were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It was confirmed that Mg-Al hydrotalcite nanocrystallites are pure and regularly hexagonal, having a typical hydrotalcite structure. The Mg-Al hydrotalcite crystals grow from about 30 nm to 100 nm with an increase in the reaction temperature from 50℃ to 90 ℃, and the crystal form also tends to perfect and regularly hexagonal. Mg-Al hydrotalcite (Mg6Al2(OH)16CO3·4H2O), the precursor of MgAl2O4 spinel, has been synthesized via a coprecipitation method, using AlCl3·6H2O and MgCl2·6H2O as the raw materials, and NaOH and Na2CO3 as the precipitators. The effect of the reaction temperature, from 50℃ to 90℃, on the Mg-Al hydrotalcite nanocrystallites was analyzed. The nanocrystallites were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It was confirmed that Mg-Al hydrotalcite nanocrystallites are pure and regularly hexagonal, having a typical hydrotalcite structure. The Mg-Al hydrotalcite crystals grow from about 30 nm to 100 nm with an increase in the reaction temperature from 50℃ to 90 ℃, and the crystal form also tends to perfect and regularly hexagonal.

Multicentre Hospital-based Case-control Study of Diffuse Large B-cell Lymphoma in Shanghai, China

Fan, Rong,Zhang, Lu-Yao,Wang, Hong,Yang, Bo,Han, Tao,Zhao, Xiao-Li,Wang, Wei,Wang, Xiao-Qin,Lin, Guo-Wei Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

Background: Several potential risk factors have been identified for diffuse large B-cell lymphoma (DLBCL); however, epidemiological studies investigating the association between these risk factors and DLBCL have yielded inconsistent results. Objectives: To investigate potential medical, lifestyle, and environmental risk factors of DLBCL in Shanghai, China through a hospital-based case-control study. Method: One-hundred-and-forty-seven newly diagnosed DLBCL patients and 294 sex- and age-matched controls were recruited from 11 hospitals in Shanghai between 2003 and 2007. A standardized structured questionnaire was used to obtain patient data on demographics, medical history, family history, lifestyle, and environmental exposures. Conditional logistic regression models were used to estimate odds ratios (ORs), with 95% confidence intervals (CIs), for risk associated with each data category. Results: History of tuberculosis (TB) infection and "living on a farm" were positively associated with DLBCL (TB: OR=3.05, 95% CI: 1.19-7.80; farm: OR=1.82, 95% CI: 1.21-2.73). In contrast, taking traditional Chinese medicine was negatively associated with DLBCL (OR=0.36, 95% CI: 0.14-0.89). No significant correlation with DLBCL risk was found for any of the other potential risk factors (p>0.05), including but not limited to hair dyes, alcohol drinking, smoking, and home/workplace renovation within one year. Conclusions: Consistent with results from previous studies in other DLBCL case populations, traditional Chinese medicine appeared to have a direct or indirect protective effect against DLBCL. However, this study also identified a possible predisposition for DLBCL in TB sufferers and farmers.

Preparation and Antitumor Activity of a Tamibarotene-Furoxan Derivative

Wang, Xue-Jian,Duan, Yu,Li, Zong-Tao,Feng, Jin-Hong,Pan, Xiang-Po,Zhang, Xiu-Rong,Shi, Li-Hong,Zhang, Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Multi-target drug design, in which drugs are designed as single molecules to simultaneously modulate multiple physiological targets, is an important strategy in the field of drug discovery. QT-011, a tamibarotene-furoxan derivative, was here prepared and proposed to exert synergistic effects on antileukemia by releasing nitric oxide and tamibarotene. Compared with tamibarotene itself, QT-011 displayed stronger antiproliferative effects on U937 and HL-60 cells and was more effective evaluated in a nude mice U937 xenograft model in vivo. In addition, QT-011 could release nitric oxide which might contribute to the antiproliferative activity. Autodocking assays showed that QT-011 fits well with the hydrophobic pocket of retinoic acid receptors. Taken together, these results suggest that QT-011 might be a highly effective derivative of tamibarotene and a potential candidate compound as antileukemia agent.

Differential Protein Expression in EC304 Gastric Cancer Cells Induced by Alphastatin

Wang, Xin-Xin,Sun, Rong-Ju,Wu, Meng,Li, Tao,Zhang, Yong,Chen, Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: To explore the differential protein expression profile in EC304 gastric cancer cells induced by alphastatin. Methods: Cultured EC304 cells in the exponential phase of growth were randomly divided into alphastatin and control groups. Total proteins were extracted and the two dimensional electrophoresis (2-DE) technique was applied to analyze differences in expression with ImageMaster 2D Platinum 5.0 software. Proteins were identified using the MASCOT database and selected differently expressed proteins were characterised by western blotting and immunofluorescence. Results: $1350{\pm}90$ protein spots were detected by the ImageMaster software in the 2-DE gel images from the control and alphastatin groups. The match rate was about 72-80% for the spectrum profiles, with 29 significantly different protein spots being identified, 10 upregulated, 16 downregulated, two new and one lost. The MASCOT search scores were 64-666 and the peptide matching numbers were 3-27 with sequence coverage of 8-62%. Twenty-three proteins were checked by mass spectrometry, including decrease in Nm23 and profilin-2 isoform b associated with the regulation of actin multimerisation induced by extracellular signals. Conclusion: The proteome in EC304 cells is dramatically altered by alphastatin, which appears to play an important role in modulating cellular activity and anti-angiogenesis by regulating protein expression and signal transduction pathways through Nm23 and profilin-2 isoform b, providing new research directions for anti-angiogenic therapy of gastric cancer.

Pyrolysis kinetics and thermal degradation characteristics of the pre-treated municipal sewage sludge by biophysical processing

( Rong Han ),( Jin-wen Liu ),( Hong-tao Wang ),( Yuan-cheng Zhang ) 한국폐기물자원순환학회 2011 ISWA Vol.2011 No.0

Pyrolysis of municipal sewage sludge (MSS) is a promising thermal conversion technology for waste disposal and energy recycle. The product yield pattern of thermal degradation process is strongly relevant to the chemical composition of MSS. In the present study, MSS was firstly processed in a biophysical conversion reactor to adjust the moisture content and biomass fraction. The pyrolysis characteristics of products from biophysical pre-treatment were investigated using thermogravimetric analysis(TGA) and differential scanning calorimetry(DSC), with the materials decomposing between 30℃ to 900℃ at heating rates of 10, 20, 40 ℃/min. According to DTG curves, the kinetic model was performed according to a combination of five-step decomposition. The approximate composition of samples can be determined by each step due to its pyrolysis feature. The nth-order kinetic equations was utilized to describe component degradations and the apparent activation energies were calculated at 25.46, 14.48, 48.15, 85.22, 60.16 kJ/mol through Coats-Redfern integral method. The first-step decomposition was related to low stability organic compounds that derived from the intermediate products of metabolism. The other four steps are mostly ascribed to the non-biodegradable components. The product gas was detected on-line by mass spectrograph (MS) coupled with TGA, indicating the thermal degradation characteristics of various components in the pre-treated sample.

Kinetic and thermodynamic study of Eu(III) sorption on natural red earth in South China

Tao Yu,Wang-Suo Wu,Zhi-Rong Liu,Si-Wei Zhang,Zheng-Wei Nie 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.2

We did a kinetic and thermodynamic study of Eu(III) sorption on natural red earth (NRE) in South China as a function of contact time, pH values, ionic strength, humic acid (HA) and temperature under ambient conditions. Linear and nonlinear regression methods in selecting the optimum sorption isotherm were applied on the experimental data. The results suggest that sorption of Eu(III) on NRE can be described by a pseudo-second-order rate equation and strongly dependent on ionic strength at pH<7. Sorption of Eu(III) on NRE increased with increasing temperature,two-parameter and three-parameter isotherms were applied to analysis the equilibrium adsorption data, and a comparison of linear and nonlinear regression methods was done. The thermodynamic parameters (ΔH0, ΔS0 and ΔG0) of Eu(III)sorption on NRE at different temperatures were calculated from the temperature-dependent sorption isotherms, indicating that the sorption process of Eu(III) was spontaneous. The results showed that the nonlinear method is a better way to obtain the isotherm parameters and the data were in good agreement with the Freundlich isotherm model.

The Yellow Sea Warm Current and the Yellow Sea Cold Bottom Water, Their Impact on the Distribution of Zooplankton in the Southern Yellow Sea

Wang, Rong,Zuo, Tao The Korean Society of Oceanography 2004 Journal of the Korean Society of Oceanography Vol.39 No.1

The Yellow Sea Warm Current (YSWC) and the Yellow Sea Cold Bottom Water (YSCBW) are two protruding features, which have strong influence on the community structure and distribution of zooplankton in the Yellow Sea. Both of them are seasonal phenomena. In winter, strong north wind drives southward flow at the surface along both Chinese and Korean coasts, which is compensated by a northward flow along the Yellow Sea Trough. That is the YSWC. It advects warmer and saltier water from the East China Sea into the southern Yellow Sea and changes the zooplankton community structure greatly in winter. During a cruise after onset of the winter monsoon in November 2001 in the southern Yellow Sea, 71 zooplankton species were identified, among which 39 species were tropical, accounting for 54.9 %, much more than those found in summer. Many of them were typical for Kuroshio water, e.g. Eucalanus subtenuis, Rhincalanus cornutus, Pareuchaeta russelli, Lucicutia flavicornis, and Euphausia diomedeae etc. 26 species were warm-temperate accounting for 36.6% and 6 temperate 8.5%. The distribution pattern of the warm water species clearly showed the impact of the YSWC and demonstrated that the intrusion of warmer and saltier water happened beneath the surface northwards along the Yellow Sea Trough. The YSCBW is a bottom pool of the remnant Yellow Sea Winter Water resulting from summer stratification and occupy most of the deep area of the Yellow Sea. The temperature of YSCBW temperature remains ${\leq}{\;}10^{\circ}C$ in mid-summer. It is served as an oversummering site for many temperate species, like Calanus sinicus and Euphaisia pacifica. Calanus sinicus is a dominant copepod in the Yellow Sea and East China Sea and can be found throughout the year with the year maximum in May to June. In summer it disappears in the coastal area and in the upper layer of central area due to the high temperature and shrinks its distribution into YSCBW.

Transcriptome analysis of differentially expressed genes in rabbits’ ovaries by digital gene-expression profiling

Tao Huang,Ya‑dong Wang,Ming‑ming Xue,Xue Feng,Cai‑Xia Sun,An‑si Wang,Shu‑yu Xie,Meng Zhang,Gui‑Rong Sun,Ming Li 한국유전학회 2018 Genes & Genomics Vol.40 No.7

Reproduction is a complex physiological process that is regulated by multiple genes and pathways. Compared with studies of common livestock, fewer studies of genes related to the fertility of rabbits (Oryctolagus cuniculus) have been reported, and the molecular mechanism of their high productivity is still poorly understood. To identify candidate genes associated with development and prolificacy in rabbits, we analyzed gene expression differences among the ovaries of mature Californian rabbit (LC), and mature (HH) and immature Harbin white rabbit (IH) using digital gene expression technology. We detected 885 and 321 genes that were significantly differentially expressed in comparisons between HH/IH and HH/LC, respectively. The functions of the differentially expressed genes (DEGs) were determined by GO classification and KEGG pathway analysis. The results suggest that most of the DEGs between the mature and immature developmental stages were predominantly associated with DNA replication, cell cycle, and progesterone-mediated oocyte maturation, and most were up-regulated in the IH group compared with the HH group. The DEGs involved in disparate fecundities between HH and LC were associated with reproduction, fructose and mannose metabolism, steroid hormone biosynthesis, and pyruvate metabolism. Our results will contribute to a better understanding of changes in the regulatory network in ovary at different developmental stages and in different fertility of rabbit.

Photothermal Therapy of Copper Incorporated Nanomaterials for Biomedicine

Rong Wang,Ziwei Huang,Yunxiao Xiao,Tao Huang,Jie Ming 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Studies have reported on the significance of copper incorporated nanomaterials (CINMs) in cancer theranostics and tissue regeneration. Given their unique physicochemical properties and tunable nanostructures, CINMs are used in photothermal therapy (PTT) and photothermal-derived combination therapies. They have the potential to overcome the challenges of unsatisfactory efficacy of conventional therapies in an efficient and non-invasive manner. This review summarizes the recent advances in CINMs-based PTT in biomedicine. First, the classification and structure of CINMs are introduced. CINMs-based PTT combination therapy in tumors and PTT guided by multiple imaging modalities are then reviewed. Various representative designs of CINMs-based PTT in bone, skin and other organs are presented. Furthermore, the biosafety of CINMs is discussed. Finally, this analysis delves into the current challenges that researchers face and offers an optimistic outlook on the prospects of clinical translational research in this field. This review aims at elucidating on the applications of CINMs-based PTT and derived combination therapies in biomedicine to encourage future design and clinical translation.

The Yellow Sea Warm Current and the Yellow Sea Cold Bottom Water, Their Impact on the Distribution of Zooplankton in the Southern Yellow Sea

Rong Wang,Tao Zuo 한국해양과학기술원 2004 Ocean science journal Vol.39 No.1

The Yellow Sea Warm Current (YSWC) and the Yellow Sea Cold Bottom Water (YSCBW) are two protruding features, which have strong influence on the community structure and distribution of zooplankton in the Yellow Sea. Both of them are seasonal phenomena. In winter, strong north wind drives southward flow at the surface along both Chinese and Korean coasts, which is compensated by a northward flow along the Yellow Sea Trough. That is the YSWC. It advects warmer and saltier water from the East China Sea into the southern Yellow Sea and changes the zooplankton community structure greatly in winter. During a cruise after onset of the winter monsoon in November 2001 in the southern Yellow Sea, 71 zooplankton species were identified, among which 39 species were tropical, accounting for 54.9 %, much more than those found in summer. Many of them were typical for Kuroshio water, e.g. Eucalanus subtenuis, Rhincalanus cornutus, Pareuchaeta russelli, Lucicutia flavicornis, and Euphausia diomedeae etc. 26 species were warm-temperate accounting for 36.6% and 6 temperate 8.5%. The distribution pattern of the warm water species clearly showed the impact of the YSWC and demonstrated that the intrusion of warmer and saltier water happened beneath the surface northwards along the Yellow Sea Trough. The YSCBW is a bottom pool of the remnant Yellow Sea Winter Water resulting from summer stratification and occupy most of the deep area of the Yellow Sea. The temperature of YSCBW temperature remains ≤10oC in mid-summer. It is served as an oversummering site for many temperate species, like Calanus sinicus and Euphaisia pacifica. Calanus sinicus is a dominant copepod in the Yellow Sea and East China Sea and can be found throughout the year with the year maximum in May to June. In summer it disappears in the coastal area and in the upper layer of central area due to the high temperature and shrinks its distribution into YSCBW.