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, Ravi,Manju Sharma,Sharma, Suman 한국유전학회 1994 Genes & Genomics Vol.16 No.4
Six Indian geographical populations of D. bipectinata were analysed electrophoretically for allozymic variation at nine loci as well as for ethanol tolerance potential. Allelic frequency changes at Adh, Odh and Est-5 loci correlated significantly with increase in latitude. On the basis of F_(ST) values, Adh, Odh, Mdh and α-Gpdh loci depicted modest amounts of genetic differentiation. Thus, the occurrence of significant genotypic as well as allelic frequency heterogeneity, genic differentiation and clinal variation at polymorphic loci suggest evidence of natural selection maintaining such genic differentiation in D. bipectinata populations from the Indian sub-continent. The Indian populations of D. bipectinata revealed genetic differentiation in term of ethanol indices such as LT_(50) hrs(72 to 96 hrs), adult ethanol threshold concentration(2.5 to 4.0'%), LC_(50) thanol concentration(2.7 to 4.2%). The parallel occurrence of latitudinal variation at Adh locus as well as ethanol tolerance in Indian geographical populations of D. bipectinata could be maintained by balancing natural selection varying spatially along the north south axis of the Indian sub-continent.
Ravi, Seenu,Ahn, Wha-Seung Elsevier 2018 Microporous and mesoporous materials Vol.271 No.-
<P><B>Abstract</B></P> <P>By varying the amount of AlCl<SUB>3</SUB> catalyst, highly interconnected lamella-shaped (IPOP) and spherically structured porous organic polymers (SPOP) were synthesized from terephthaloyl chloride and <I>p</I>-quaterphenyl via the Friedel–Crafts benzoylation reaction. The newly prepared materials were characterized by scanning electron microscopy, N<SUB>2</SUB> adsorption-desorption isotherms, X-ray photoelectron spectroscopy, and tested for Hg<SUP>2+</SUP> removal in water after functionalization with 2-aminoethanethiol (NS). The stability under different pH and temperature conditions was confirmed, and the equilibrium and kinetics of Hg<SUP>2+</SUP> adsorption were examined by varying the contact time, adsorbate concentration, and pH. The maximum adsorption capacities for Hg<SUP>2+</SUP> by IPOP-NS and SPOP-NS were 769 and 526 mg g<SUP>−1</SUP>, respectively, at 25 °C and pH 5, and the adsorption isotherm data conformed well to the Langmuir model. Adsorption equilibrium for IPOP-NS was reached within 10 min and exhibited a remarkable distribution coefficient of 1.06 × 10<SUP>8</SUP> mL g<SUP>−1</SUP>. The kinetics of Hg<SUP>2+</SUP> adsorption followed the pseudo-second-order model. The influence of co-existing ions such as Na<SUP>+</SUP>, K<SUP>+</SUP>, Ca<SUP>2+</SUP>, Pb<SUP>2+</SUP>, Mg<SUP>2+</SUP>, and Fe<SUP>3+</SUP> was also examined. IPOP-NS was superior in overall performance when compared to SPOP-NS and most of the other reported materials. IPOP-NS could be reused for a minimum of 10 consecutive runs without any detectable loss in adsorption capacity.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel mesoporous polymers were synthesized (IPOP/SPOP) and grafted with 2-aminoethanethiol (NS). </LI> <LI> IPOP-NS exhibited exceptional Hg<SUP>2+</SUP> capture of 769 mg g<SUP>−1</SUP> in water with fast kinetics. </LI> <LI> IPOP-NS showed high stability in boiling water, aqueous HCl, and NaOH. </LI> <LI> IPOP-NS was reusable 10 cycles without deterioration in adsorption capacities. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Compelling therapy of LVH: straight (and not-so-straight) inferences from evidence
Ravi Tejraj Mehta,Anil Pareek,Shruti Dharmadhikari 대한고혈압학회 2020 Clinical Hypertension Vol.26 No.1
We have read with interest the Korean Society of Hypertension guidelines for the management of hypertension and congratulate the Society for an extensive review of literature while drafting the guidelines. The guidelines indicate preferring ACE-I and CCB over diuretics in patients with left ventricle hypertrophy. However, in landmark head-to-head comparison trials, the thiazide-like diuretic chlorthalidone has been shown to be superior to ACE-I and CCB in decreasing left ventricle mass and preventing heart failure in hypertensive patients. Also, we put forth the paradoxical finding that mere regression of LVH may not always translate into reduction in risk of HF; and that the pleiotropic effects of chlorthalidone may be the explanation behind its beneficial action in HF.
Expiration-Day Effects on Index Futures: Evidence from Indian Market
Ravi Kumar SAMINENI,Raja Babu PUPPALA,Ramesh MUTHANGI,Syamsundar KULAPATHI 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11
Nifty Bank Index has started trading in futures and options (F&O) segment from 13th June 2005 in National Stock Exchange. The purpose of the study is to enhance the literature by examining expiration effect on the price volatility and price reversal of Underlying Index in India. Historical data used for the current study primarily comprise of daily close prices of Nifty Bank which is the only equity sectoral index in India which is traded in derivatives market and its Future contract value is derived from the underlying CNX Bank Index during the period 1st January 2010 till 31st March 2020. To check stationarity of the data, Augmented Dicky Fuller test was used. The study employed ARMA- EGARCH model for analysing the data. The empirical results revealed that there is no effect on the mean returns of underlying Index and EGARCH (1,1) model furthermore shows there is existence of leverage effect in the Bank Index i.e., negative shocks causes more fluctuations in the Index than positive news of similar magnitude. The outcome of the study specifies that there is no effect on volatility on the underlying sectoral index due to expiration days and also observed no price reversal effect once the expiration days are over.
Ravi Kumar H. S.,Vijay G Goni,Batra Y. K. 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.6
Study Design: The study was conducted on patients who received autologous conditioned serum (ACS) as a line of treatment at the Orthopedics outpatient department of Post Graduate Institute of Medical Education and Research (PGIMER, Chandigarh) from January 2011 to June 2012. Of the 1,224 patients, 20 males or females were included in the study based on the inclusion and exclusion criteria. The institutional board of PGIMER approved the study before it was initiated. Purpose: To study the efficacy of ACS in the treatment of unilateral lumbar radiculopathy. Overview of Literature: Interleukin (IL)-1 appears to be of special importance among the cytokines identified in orthopedic diseases. ACS contains high concentrations of IL-1 receptor antagonist, antagonist to IL-1 in that is a biochemical ‘sensitizer’ of nerve roots in radiculopathy. Methods: We included 20 patients with unilateral lumbar radiculopathy after obtaining informed consent. We prepared ACS as described by Meijer et al. Under bi-planar fluoroscopic imaging in anterior-posterior and lateral views, ACS was administered via epidural perineural technique. Patients in both groups were evaluated by quadruple visual analogue scale, straight leg raising test, revised Oswestry disability index, and 12-Item Short Form of Health Survey before and after epidural injections at 3 weeks, 3 months, and 6 months. Results: There was a statistically significant change in all parameters from pre-injection to first, second, and third follow-up (p <0.001). Conclusions: ACS can modify the disease course in addition to reducing pain, disability and improving general health.
Isolation of Phytosterols and Antihyperlipidemic Activity of Lagenaria siceraria
Ravi P. Kalsait,Pramod B. Khedekar,Ashok N. Saoji,Kishor P. Bhusari 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.10
Lagenaria siceraria (Molina) Standl in the Cucurbitaceae family is a large, pubescent, climbing, or trailing herb cultivated throughout India and the tropical regions of the world. Phytochemical investigation of the methanol extract obtained from the fruits of the plant L. siceraria showed a positive Liebermann-Burchard test for sterols. The white sterol crystals or phytosterols from the methanol extract were isolated for the first time and identified as a mixture of four sterols, including fucosterol (1), racemosol (2), stigmasterol (3), and stigmasta-7,22-dien-3β,4β-diol (4). These compounds were identified by spectroscopic evidence including FTIR, 1H-NMR, MS, and GC. The white sterol crystals, which are the mixture of four sterols, were evaluated for antihyperlipidemic activity in Wistar rats. The blood samples were collected from the retro-orbital plexus and serum was separated and analyzed for lipid profiles. These sterol crystals (30 mg/kg) showed significant reductions in lipid profiles which included cholesterol, triglycerides, LDL and VLDL. In addition, a significant increase in HDL cholesterol observed, which is a good cholesterol that protects hearts from coronary artery diseases. These sterol crystals or phytosterols can be used as an antihyperlipidemic agent to treat the hyperlipidemic.
Characterization of green ceramic-aluminum composites developed from waste recycling
Ravi Kumar Singh,Ali Algahtani,Tawfiq Al-Mughanam,Intezar Mahdi,Vineet Tirth 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.3
Green composites were prepared by recycling waste Aluminum and ceramic debris of marble and granite stones obtainedduring stone cutting at building construction sites. The composites were developed using the most economical stir castingprocess under ambient conditions with five weight percent of white marble powder and black granite powders. Themicrostructure characterization was done with my optical and SEM micrography as well as XRD. The microstructure showsfair particle distribution and improved hardness by 22-25% than the base matrix. The tensile strength and elastic modulusalso improved. The density remained stagnant due to porosity. A decline in elongation and impact strength was observed. Thestudy recommends using waste Aluminum and waste ceramic powders to develop green composites for non-critical industrialapplications such as structures, furniture, stationary machine parts, and automobile chassis.