Baseline susceptibility of Asian corn borer (Ostrinia furnacalis (Guenée)) populations in Vietnam to Cry1Ab insecticidal protein

Duc Khanh Le,Quang Khai Le,Thi Thuy Hang Tran,Duc Viet Nguyen,Thi Hang Dao,Thi Thuy Nguyen,Xuan Lam Truong,Quang Cuong Nguyen,Huy Phong Pham,Thi Thu Thuy Phan,Gajendra Babu Baktavachalam 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.2

Susceptibility of Asian corn borer (ACB), Ostrinia furnacalis (Guenée) to Bacillus thuringiensis (Bt) Cry1Ab protein was studied between 2015 and 2016 with 11 ACB populations, collected from various geographical regions in Vietnam. A concentration range of Cry1Ab from 0.20 to 26.10 ng/cm 2 of diet was evaluated against F 1 ACB neonates using diet surface-overlay bioassays. Mortality data was recorded daily until seven days after infestation. Growth inhibition was recorded at the end of seven days. The median lethal concentration (LC 50 ) varied ≈3-fold among the different populations, ranging from 0.58 to 1.83 ng/cm 2 of diet with an overall mean of 0.86 ng/cm 2 of diet. Even the lowest concentration of 0.20 ng/cm 2 caused 73.53% growth inhibition. > 90% growth inhibition was achieved at 0.82 ng/cm 2 or higher concentrations. The results reflect natural variation in Bt susceptibility among ACB populations rather than variation caused by prior exposure to selection pressures. LC 99 value (17.26 ng/cm 2 ) was generated by pooling mortality data across different populations. The upper fiducial limit of LC 99 (24.38 ng/cm 2 ) could be a potential diagnostic dose for future resistance monitoring programs. The findings from this study suggest that ACB populations in Vietnam are highly susceptible to Cry1Ab protein. This is the first report of Cry1Ab susceptibility of different ACB populations in Vietnam and will serve as a baseline for future resistance monitoring work.

Right lumbar lymph trunk injury after right laparoscopic donor nephrectomy: a case report

Le Thanh Dung,Le Nguyen Vu,Than Van Sy,Tran Ha Phuong,Ninh Viet Khai,Dao Xuan Hai,Nguyen Quang Nghia 대한이식학회 2023 Korean Journal of Transplantation Vol.37 No.2

Laparoscopic donor nephrectomy (LDN) is increasingly popular because of its advantages over open surgery. Chyle leak after donor nephrectomy is a rare but potentially lethal complication if not treated appropriately. We describe a case of a 43-year-old female patient with no remarkable history who presented a chyle leak on day 2 after right transperitoneal LDN. Since conservative treatment failed, the patient underwent magnetic resonance imaging (MRI) and intranodal lipiodol lymphangiography, which confirmed the chyle leak from the right lumbar lymph trunk into the right renal fossa. The chyle leak was percutaneously embolized twice, on postoperative day (POD) 5 and POD 10, by a mixture of N-butyl-2-cyanoacrylate and lipiodol. The drainage fluid decreased significantly after the second embolization. The subhepatic drainage tube was withdrawn on POD 14, and the patient was discharged on POD 17. MRI lymphangiography and intranodal lipiodol lymphangiography effectively identified the chyle leak point. Percutaneous embolization seems to be a safe, effective method for treating high-output chyle leaks.

Outcomes of liver transplantation for hepatocellular carcinoma: Experiences from a Vietnamese center

Khai Viet Ninh,Dang Hai Do,Trung Duc Nguyen,Phuong Ha Tran,Tuan Hoang,Dung Thanh Le,Nghia Quang Nguyen 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1

Backgrounds/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors. Methods: This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS). Results: Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and Child- Pugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05). Conclusions: In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.

Linkage Between Exchange Rate and Stock Prices: Evidence from Vietnam

DANG, Van Cuong,LE, Thi Lanh,NGUYEN, Quang Khai,TRAN, Duc Quang Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.12

The study investigates the asymmetric effect of exchange rate changes on stock prices in Vietnam. We use the nonlinear autoregressive-distributed lag (ARDL) analysis for monthly data from 2001:01 to 2018:05, based on VN-Index stock price collected from Ho Chi Minh Stock Exchange (HOSE); the nominal exchange rate is separated into currency depreciation and appreciation through a partial sum decomposition process. Asymmetry is estimated both in the long-run relationship and the short-run error correction mechanism. The research results show that the effect of exchange rate changes on stock prices is asymmetrical, both in the short run and in long run. Accordingly, the stock prices react to different levels to depreciation and appreciation. However, the currency appreciation affects a stronger transmission of stock prices when compared to the long-run currency depreciation. In the absence of asymmetry, the exchange rate only has a short-run impact on stock prices. This implies a symmetrical assumption that underestimates the impact of exchange rate changes on stock prices in Vietnam. This study points to an important implication for regulators in Vietnam. They should consider the relationship between exchange rate changes and stock prices in both the long run and the short run to manage the stock and foreign exchange market.

Surface plasmon-assisted optical switching/bistability at telecommunication wavelengths in nonlinear dielectric gratings

Thu Trang Hoang,Khai Q. Le,Quang Minh Ngo 한국물리학회 2015 Current Applied Physics Vol.15 No.9

In this paper, we numerically investigate nonlinear optical responses in dielectric gratings coated by flat metallic surface, where the structural parameters are chosen for wavelengths of operation at the telecom regime. The presented designs show the output light reflection with respect to the incident intensity of increasing, decreasing, and non-monotonic belt-shape functions. Nonlinear optical responses including switching and bistability appeared in the telecom region owing to assistance of surface plasmon resonance excited at the metal/dielectric interface, which enhances the diffraction efficiency and induces the momentum matching for the leaky modes of the dielectric grating. This results in electric intensityeffective refractive index dependence enhancement in the Kerr nonlinear media. Our design and investigation of the linear and nonlinear optical responses will provide a general guideline for a hybrid metallic-dielectric structure-based optical switching/bistability device design.

Coffee Husk By-Product as Novel Ingredients for Cascara Kombucha Production

( Bao Xuyen Nguyen Le ),( Thach Phan Van ),( Quang Khai Phan ),( Gia Bao Pham ),( Hoa Pham Quang ),( Anh Duy Do ) 한국미생물생명공학회 2024 Journal of microbiology and biotechnology Vol.34 No.3

Kombucha, a fermented beverage, is gaining popularity due to its numerous beneficial health effects. Various substrates such as herbs, fruits, flowers, and vegetables, have been used for kombucha fermentation in order to enhance the flavor, aroma, and nutritional composition. This study aims to investigate the potential suitability of cascara as a novel ingredient for kombucha production. Our findings suggested that cascara is a suitable substrate for kombucha production. Fermentation elevated the total phenolic and flavonoid content in cascara, which enhanced the antioxidant, antibacterial, and prebiotic characteristics of the product. Furthermore, the accumulation of acetic acid-induced the pH lowering reached 2.7 after 14 days of fermentation, which achieved the microbiological safety of the product. Moreover, 14 days of fermentation resulted in a balanced amalgamation of acidity, sweetness, and fragrance according to sensory evaluation. Our findings not only highlight the potential of cascara kombucha as a novel substrate for kombucha production but also contribute to repurposing coffee by-products, promoting environmentally friendly and sustainable agricultural development.

Epsilon-Near-Zero Enhanced Plasmonic Brewster Transmission Through Subwavelength Tapered Metallic Gratings

Phuc Toan Dang,Truong Khang Nguyen,Khai Quang Le,Tan Thi Pham 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.72 No.1

Recently, epsilon-near-zero (ENZ) materials have been employed to stimulate light funnelling enhancement through a subwavelength metallic channel. In this paper, we present a study of enhanced optical transmission through subwavelength metallic gratings deposited on ENZ material and gallium-arsenide (GaAs) substrate. We propose to carve periodically tapered slits on the metallic grating to enable the impedance matching at the entrance and exit faces and thus enhance the light transmission at the plasmonic Brewster angle. The optimal grating geometry provides around 80% average transmission over a broad bandwidth from 5 THz to 20 THz at the incident Brewster angle of 76. Our study extends potential practical applications of ENZ materials for integrated photonics.

Bradycardia and Slowing of the Atrioventricular Conduction in Mice Lacking Ca _V 3.1/α _1G T-Type Calcium Channels

Mangoni, Matteo E.,Traboulsie, Achraf,Leoni, Anne-Laure,Couette, Brigitte,Marger, Laurine,Le Quang, Khai,Kupfer, Elodie,Cohen-Solal, Anne,Vilar, José,Shin, Hee-Sup,Escande, Denis,Charpentier, Fl Ovid Technologies Wolters Kluwer -American Heart A 2006 Circulation research Vol.98 No.11

<P>The generation of the mammalian heartbeat is a complex and vital function requiring multiple and coordinated ionic channel activities. The functional role of low-voltage activated (LVA) T-type calcium channels in the pacemaker activity of the sinoatrial node (SAN) is, to date, unresolved. Here we show that disruption of the gene coding for CaV3.1/alpha1G T-type calcium channels (cacna1g) abolishes T-type calcium current (I(Ca,T)) in isolated cells from the SAN and the atrioventricular node without affecting the L-type Ca2+ current (I(Ca,L)). By using telemetric electrocardiograms on unrestrained mice and intracardiac recordings, we find that cacna1g inactivation causes bradycardia and delays atrioventricular conduction without affecting the excitability of the right atrium. Consistently, no I(Ca,T) was detected in right atrium myocytes in both wild-type and CaV3.1(-/-) mice. Furthermore, inactivation of cacna1g significantly slowed the intrinsic in vivo heart rate, prolonged the SAN recovery time, and slowed pacemaker activity of individual SAN cells through a reduction of the slope of the diastolic depolarization. Our results demonstrate that CaV3.1/T-type Ca2+ channels contribute to SAN pacemaker activity and atrioventricular conduction.</P>