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      • Design of Active Measurement System for Voltage Transformer Error Test

        Li, Ye,Kai-Qi, Shu,Li, Shen,Si-Ke, Wang 대한전기학회 2014 The Journal of International Council on Electrical Vol.4 No.4

        In order to adapt to the error test of the field voltage transformer, solve the problems of the current measuring method, this paper presents the way of using computer control instead of manual control to measure voltage transformer error actively based on WiFi, automatic measure the actual load of the boost circuit, real-time monitoring of the circuit parameters and protection control. At the same time, It realized the whole process information management of measured data, from automatic colletion, analyze to saving, greatly improve of the safety and the efficiency of the work.

      • KCI등재

        Comparative analysis of type 2 diabetes-associated gut microbiota between Han and Mongolian people

        Shu-chun Li,Yao Xiao,Ri-tu Wu,Dan Xie,Huan-hu Zhao,Gang-yi Shen,En-qi Wu 한국미생물학회 2021 The journal of microbiology Vol.59 No.7

        Due to the different rates of diabetes in different ethnic groupsand the structural differences in intestinal microbiota, thisstudy evaluated the changes in diabetes-related intestinal microbiotain two ethnic groups. Fifty-six stool samples werecollected from subjects from the Han and Mongolian ethnicgroups in China, including participants without diabetes(non-diabetic, ND) and with type 2 diabetes (T2D). The 16SrDNA gene V3 + V4 area was extracted from microbiota,amplified by PCR, and used to perform high-throughput sequencingand screen differential microbiota associated withethnicity. The results showed that there were 44 T2D-relatedbacterial markers in the Han subjects, of which Flavonifractor,Alistipes, Prevotella, Oscillibacter, Clostridium XlVa,and Lachnospiracea_incertae_sedis were most closely relatedto diabetes. There were 20 T2D-related bacterial markers inthe Mongolian subjects, of which Fastidiosipila and Barnesiellawere most closely related to diabetes. The commonmarkers of T2D bacteria in the two ethnic groups were Papillibacterand Bifidobacterium. There were 17 metabolic pathwayswith significant differences between the ND and T2Dgroups in the Han group, and 29 metabolic pathways in theMongolian group. The glutamatergic metabolic pathway wasthe only common metabolic pathway in two ethnic groups. The composition and function of diabetes-related bacteriawere significantly different among the different ethnic groups,which suggested that the influence of ethnic differences shouldbe fully considered when studying the association betweendiabetes and bacteria. In addition, the common bacterialmarkers found in diabetic patients of different ethnic groupsin this study can be used as potential targets to study the pathogenesisand treatment of diabetes.

      • KCI등재

        A Noninjection Reaction Route to CuInSe2 Nanocrystals with Triethanolamine as the Complexing Agent

        Qi-Yi Zhang,Wen-Long Liu,Meng-Qiang Wu,Ru-Chao Zhou,Li-Dan Yan,Shu-Ren Zhang 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.12

        The chalcopyrite-type CuInSe_2 is a remarkable material for thin film solar cells owing to its electronic structure and optical response. Single-phase sphere-like CuInSe_2 nanocrystallite particles were prepared by a facile noninjection method with triethanolamine as the complexing agent and the solvent simultaneously. The period of the reaction was the key to form single-phase CuInSe_2 nanocrystals at 240 ^oC. TEM, XRD, XPS, EDX investigations were performed to characterize the morphology and the detailed structure of as-synthesized CuInSe_2 nanocrystals. All of the analysis results proved that the synthesized nanocrystals were pure phase and close to the stoichiometric ratio rather than a simple mixture. The band gap of the obtained CuInSe_2nanocrystals was 1.03 ± 0.03 eV.

      • Root Health Evaluation of Different Alfalfa Varieties in Agricultural and Animal Husbandly Areas

        Qi-zhong Sun,Li-jun Xu,Zhu Yu,Shu-fen Zhao 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08

        Research on alfalfa root morphology and health is very important in development of technology for efficient improvement and production of alfalfa. The objectives of this study were to evaluate the root morphology and health of two alfalfa varieties, Algonquin and Golden Queen, to determine relationships among root morphology traits and root health. Results from these analyses indicated t㏊t yield was 6.77-43.93 t/h㎡, total root length ranged from 215.17-708.89 ㎜, root surface area ranged from 93.61-717.06 ㎠, volume ranged from 3.24-57.72㎤. Results from these analyses indicated t㏊t root infestation score was the lowest averaged over age of alfalfa stand in Algonquin. Yield in 2-yr old stands was greater in Golden Queen compared to Algonquin.

      • KCI등재

        Synthesis of Tailed Metalloporphyrins Modified with 2-Chloronicotinic Acid and Interactions with Human Serum Albumin

        Shu-Jun Wang,Yu-Ling Peng,Cheng-Gen Zhang,Qi Peng Ma,Xiao Xia Peng,Li Lei Ren 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.7

        Two kinds of free-base tailed porphyrins modified with 2-chloronicotinic acid and the corresponding Zn porphyrins have been synthesized. They have been characterized by elemental analysis and NMR, UV/Vis, fluorescence spectra, and infrared spectroscopies. Their configurations have been optimized through theoretical calculations. The fluorescence quantum yields were determined by a comparative method. The interactions between the Zn porphyrins and human serum albumin have been studied by means of fluorescence spectra. The experimental results showed that the interaction mechanism involved a combined fluorescence quenching process (static and dynamic quenching) and that the main driving force was hydrophobic in nature. Quenching constants, binding constants, thermodynamic parameters, and binding distances have been determined.

      • Roles of E-Cadherin (CDH1) Genetic Variations in Cancer Risk: a Meta-analysis

        Deng, Qi-Wen,He, Bang-Shun,Pan, Yu-Qin,Sun, Hui-Ling,Xu, Ye-Qiong,Gao, Tian-Yi,Li, Rui,Song, Guo-Qi,Wang, Shu-Kui Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

        E-Cadherin (CDH1) genetic variations may be involved in invasion and metastasis of various cancers by altering gene transcriptional activity of epithelial cells. However, published studies on the association of CDH1 gene polymorphisms and cancer risk remain contradictory, owing to differences in living habits and genetic backgrounds. To derive a more better and comprehensive conclusion, the present meta-analysis was performed including 57 eligible studies of the association between polymorphisms of CDH1 gene promoter -160 C>A, -347 G>GA and 3'-UTR +54 C>T and cancer risk. Results showed that these three polymorphisms of CDH1 were significantly associated with cancer risk. For -160 C>A polymorphism, -160A allele carriers (CA and CA+AA) had an increased risk of cancer compared with the homozygotes (CC), and the similar result was discovered for the -160A allele in the overall analyses. In the subgroup analyses, obvious elevated risk was found with -160A allele carriers (AA, CA, CA+AA and A allele) for prostate cancer, while a decreased colorectal cancer risk was shown with the AA genotype. For the -347 G>GA polymorphism, the GAGA genotype was associated with increased cancer risk in the overall analysis with homozygous and recessive models. In addition, results of subgroup analysis indicated that the elevated risks were observed in colorectal cancer and Asian descendants. For +54 C>T polymorphism, a decreased risk of cancer was found in heterozygous, dominant and allele models. Moreover, +54T allele carriers (CT, CT+TT genotype and T allele) showed a potential protective factor in gastric cancer and Asian descendants.

      • KCI등재

        Causal Relations between Exposome and Stroke: A Mendelian Randomization Study

        Hong-Qi Li,Yi-Wei Feng,Yu-Xiang Yang,Xin-Yi Leng,Prof Can Zhang,Shi-Dong Chen,Kevin Kuo,Shu-Yi Huang,Xue-Qing Zhang,Yi Dong,Xiang Han,Xin Cheng,Mei Cui,Lan Tan,Qiang Dong,Jin-Tai Yu 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.2

        Background and Purpose To explore the causal relationships of elements of the exposome with ischemic stroke and its subtypes at the omics level and to provide evidence for stroke prevention. Methods We conducted a Mendelian randomization study between exposure and any ischemic stroke (AIS) and its subtypes (large-artery atherosclerotic disease [LAD], cardioembolic stroke [CE], and small vessel disease [SVD]). The exposure dataset was the UK Biobank involving 361,194 subjects, and the outcome dataset was the MEGASTROKE consortium including 52,000 participants. Results We found that higher blood pressure (BP) (systolic BP: odds ratio [OR], 1.02; 95% confidence interval [CI], 1.01 to 1.04; diastolic BP: OR, 1.03; 95% CI, 1.01 to 1.05; pulse pressure: OR, 1.03; 95% CI, 1.00 to 1.06), atrial fibrillation (OR, 1.18; 95% CI, 1.13 to 1.25), and diabetes (OR, 1.13; 95% CI, 1.07 to 1.18) were significantly associated with ischemic stroke. Importantly, higher education (OR, 0.69; 95% CI, 0.60 to 0.79) decreased the risk of ischemic stroke. Higher systolic BP (OR, 1.06; 95% CI, 1.02 to 1.10), pulse pressure (OR, 1.08; 95% CI, 1.02 to 1.14), diabetes (OR, 1.28; 95% CI, 1.13 to 1.45), and coronary artery disease (OR, 1.58; 95% CI, 1.25 to 2.00) could cause LAD. Atrial fibrillation could cause CE (OR, 1.90; 95% CI, 1.71 to 2.11). For SVD, higher systolic BP (OR, 1.04; 95% CI, 1.00 to 1.07), diastolic BP (OR, 1.06; 95% CI, 1.01 to 1.12), and diabetes (OR, 1.22; 95% CI, 1.10 to 1.36) were causal factors. Conclusions The study revealed elements of the exposome causally linked to ischemic stroke and its subtypes, including conventional causal risk factors and novel protective factors such as higher education.

      • KCI등재

        Ultrasonography in Acupuncture—Uses in Education and Research

        Mabel Qi He Leow,Shu Li Cui,Mohammad Taufik Bin Mohamed Shah,Taige Cao,Shian Chao Tay,Peter Kay Chai Tay,Chin Chin Ooi 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.3

        This study aims to explore the potential use of ultrasound in locating the second posterior sacral foramen acupuncture point, quantifying depth of insertion and describing surrounding anatomical structures. We performed acupuncture needle insertion on a study team member. There were four steps in our experiment. First, the acupuncturist located the acupuncture point by palpation. Second, we used an ultrasound machine to visualize the structures surrounding the location of the acupuncture point and measure the depth required for needle insertion. Third, the acupuncturist inserted the acupuncture needle into the acupuncture point at an angle of 30°. Fourth, we performed another ultrasound scan to ensure that the needle was in the desired location. Results suggested that ultrasound could be used to locate the acupuncture point and estimate the depth of needle insertion. The needle was inserted to a depth of 4.0 cm to reach the surface of the sacral foramen. Based on Pythagoras theorem, taking a needle insertion angle of 30° and a needle insertion depth of 4.0 cm, the estimated perpendicular depth is 1.8 cm. An ultrasound scan corroborated the depth of 1.85 cm. The use of an ultrasound-guided technique for needle insertion in acupuncture practice could help standardize the treatment. Clinicians and students would be able to visualize and measure the depth of the sacral foramen acupuncture point, to guide the depth of needle insertion. This methodological guide could also be used to create a standard treatment protocol for research. A similar mathematical guide could also be created for other acupuncture points in future.

      • Tanshinone II-A Inhibits Angiogenesis through Down Regulation of COX-2 in Human Colorectal Cancer

        Zhou, Li-Hong,Hu, Qiang,Sui, Hua,Ci, Shu-Jun,Wang, Yan,Liu, Xuan,Liu, Ning-Ning,Yin, Pei-Hao,Qin, Jian-Min,Li, Qi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

        Angiogenesis plays a significant role in colorectal cancer (CRC) and cyclooxygenase-2 (COX-2) appears to be involved with multiple aspects of CRC angiogenesis. Our aim was to investigate the inhibitory effects of Tan II-A (Tanshinone II-A, Tan II-A) on tumor growth in mice, as well as alteration of expression of COX-2 and VEGF in CRC. We established the mice xenograft model of C26 CRC cell line, and injected 0.5, 1, 2mg/kg of Tan II-A and 1mg/kg of 5-FU in respectively in vivo. Then, we assayed tumor weight and volume, and evaluated microvascular density and expression of VEGF. COX-2 promoter and COX-2 plasmids were transfected into HCT-116 cells, followed by detection of COX-2 promoter activity by chemiluminescence, and detection of COX-2 mRNA expression by fluorescence quantitative PCR. Taken together, the results showed Tan II-A could inhibit tumor growth and suppress the VEGF level in vivo. HCT-116 cell experiments showed marked inhibitory effects of Tan II-A on COX-2 and VEGF in a dose-dependent manner. The results indicate that Tan II-A can effectively inhibit tumor growth and angiogenesis of human colorectal cancer via inhibiting the expression level of COX-2 and VEGF.

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