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Pedro Tiago,Pereira Pedro,Costa Ana Sofia,Almeida Fábio,Loureiro Maria Luísa,Alfaiate Teresa,Gonçalves Abílio 대한신경집중치료학회 2022 대한신경집중치료학회지 Vol.15 No.1
Background: Blood pressure variability (BPV) is a predictor of short- and long-term disability in patients with acute ischemic stroke (AIS). Its effect on more immediate functional outcomes has been seldom studied, and the results are inconsistent. We aimed to determine the role of BPV during the first 5 days of hospitalization in functional status at the time of discharge of patients with AIS.Methods: We enrolled 134 patients diagnosed with AIS and BPV using standard deviation and coefficient of variation (CV %). These were associated with the dichotomized modified Rankin Scale at discharge using logistic regression. Results: Patients with unfavorable outcomes were significantly older (P=0.014), had a lower body mass index (P=0.001), were less likely to present with dyslipidemia (P=0.001), had lower serum triglyceride levels (P=0.012), had a longer hospitalization period (P<0.001), and had a higher mean National Institutes of Health Stroke Scale score at admission (P<0.001). After adjusting for multiple confounders, the CV % of systolic blood pressure (SBP) in the first 120 hours after admission had a significant effect on functional disability at discharge. Conclusion: Variability in SBP in the first 5 days of hospitalization had a deleterious effect on the functional outcomes at discharge of patients with AIS. The role of diabolic blood pressure variability seems to be significant only in the first 24 hours of admission; however, further research is required.
Physiological adaptations induced by swimming in mice fed a high fat diet
Pedro Augusto Silva Nogueira,Miriam Pimenta Pereira,Jeferson José Gomes Soares,Anderson Ferraz Norton Filho,Izadora Mayumi Fujinami Tanimoto,Ivana Alice Teixeira Fonseca,Homero Oliveira Avelar,Francoi 한국운동재활학회 2017 JER Vol.13 No.3
This study examined physiological variables of animals fed with a high-fat diet (HFD) or with a normal diet (ND) subjected to swimming at low and moderate level. Over 16 weeks, a group of animals was fed with HFD or ND, and at the 8 weeks, they started swimming with 50% or 80% of the maximum load achieved in the progressive work test. Weekly, body weight and the amount of ingested food were registered. The gly-cemic level was measured at the beginning, middle and at the end of the experiment. Adipose tissue, gastrocnemius muscles and hearts were collected for morphometry. The results showed that the animals fed an HFD had a minor caloric intake; however, the HFD increased body weight and adiposity, likely causing cardiac hypertrophy and an increase in the glycemic level. In this context, swimming with an 80% load contributed positively to weight control, adiposity, glycemic level, to control cardiac hypertrophy and induce hypertrophy in the gastroc-nemius muscle. All parameters assessed showed better results for the ND animals. Therefore, the importance of fat consumption was empha-sized in relation to obesity onset. The practice of swimming with an 80% load produced greater benefits than swimming with a 50% load for overweight treatment.
Maria Janice Pereira Lopes,Gyllyandeson de Arau´jo Delmondes,Giovana Mendes de Lacerda Leite,De´bora Rejane Alves Cavalcante,Pedro E´ verson Alexandre de Aquino,Francisco Arnaldo Viana de Lima,Kelly R 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.7
Spirulina platensis is a cyanobacterium with high protein content and presenting neuroprotective effects. Now, we studied a protein-enriched fraction (SPF), on behavior, neurochemical and immunohistochemical (IHC) assays in hemiparkinsonian rats, distributed into the groups: SO (sham-operated), 6-hydroxydopamine (6-OHDA), and 6-OHDA (treated with SPF, 5 and 10 mg/kg, p.o., 15 days). Afterward, animals were subjected to behavioral tests and euthanized, and brain areas used for neurochemical and IHC assays. SPF partly reversed the changes in the apomorphine-induced rotations, open field and forced swim tests, and also the decrease in striatal dopamine and 3,4-dihydroxyphenylacetic acid contents seen in hemiparkinsonian rats. Furthermore, SPF reduced brain oxidative stress and increased striatal expressions of tyrosine hydroxylase and dopamine transporter and significantly reduced hippocampal inducible nitric oxide synthase, cyclooxygenase-2 and glial fibrillary acidic protein expressions. The data suggest that the protein fraction from S. platensis, through its brain anti-inflammatory and antioxidative actions, exerts neuroprotective effects that could benefit patients affected by neurodegenerative diseases, like Parkinson's disease.
Self-sustained n-Type Memory Transistor Devices Based on Natural Cellulose Paper Fibers
Martins, Rodrigo,Pereira, Luis,Barquinha, Pedro,Correia, Nuno,Goncalves, Goncalo,Ferreira, Isabel,Dias, Carlos,Correia, N.,Dionisio, M.,Silva, M.,Fortunato, Elvira The Korean Infomation Display Society 2009 Journal of information display Vol.10 No.4
Reported herein is the architecture for a nonvolatile n-type memory paper field-effect transistor. The device was built via the hybrid integration of natural cellulose fibers (pine and eucalyptus fibers embedded in resin with ionic additives), which act simultaneously as substrate and gate dielectric, using passive and active semiconductors, respectively, as well as amorphous indium zinc and gallium indium zinc oxides for the gate electrode and channel layer, respectively. This was complemented by the use of continuous patterned metal layers as source/drain electrodes.
Tibial-graft fixation methods on anterior cruciate ligament reconstructions: a literature review
( Vitor Luis Pereira ),( João Victor Medeiros ),( Gilvan Rodrigues Silva Nunes ),( Gabriel Taniguti De Oliveira ),( Alexandre Pedro Nicolini ) 대한슬관절학회 2021 대한슬관절학회지 Vol.33 No.-
Introduction: Anterior cruciate ligament (ACL) reconstruction is the most performed orthopedic surgical procedure. The result of ACL reconstructions depends on multiple technical variables, including tension to be applied to the graft for fixation, knee-flexion angle during fixation and the type of fixation to the bone. Objective: To carry out a survey of the literature with the best evidence on these themes. Methods: Literature review about methods of tibial-graft fixation in ACL reconstructions - tension applied at the time of fixation, type of graft fixation, and knee-flexion degree during tibial fixation. Results: Thirty studies on the selected topics were found. Most studies point to graft-tension levels close to 90 N to obtain the best results. Regarding the knee-flexion angle, multiple studies suggest that fixation at a 30° angle would bring superior biomechanical advantages. Regarding the type of implant for fixation, it is not possible to affirm the superiority of one method over another in clinical outcomes. Conclusions: There is no consensus on the best method for tibial fixation of the grafts in ACL reconstructions regarding tension, type of implant and knee-flexion angle. However, the analysis of the studies pointed to certain trends and allowed the drawing of specific conclusions.
Self-sustained n-Type Memory Transistor Devices Based on Natural Cellulose Paper Fibers
Rodrigo Martins,Luís Pereira,Pedro Barquinha,Nuno Correia,Gonçalo Gonçalves,Isabel Ferreira,Carlos Dias,Elvira Fortunato,N. Correia,M. Dionísio,M. Silva 한국정보디스플레이학회 2009 Journal of information display Vol.10 No.4
Reported herein is the architecture for a nonvolatile n-type memory paper field-effect transistor. The device was built via the hybrid integration of natural cellulose fibers (pine and eucalyptus fibers embedded in resin withionic additives), which act simultaneously as substrate and gate dielectric, using passive and active semiconductors, respectively, as well as amorphous indium zinc and gallium indium zinc oxides for the gate electrode and channel layer, respectively. This was complemented by the use of continuous patterned metal layers as source/drain electrodes.
El-Tahawy, Moustafa,Pereira, Pedro Henrique R.,Huang, Yi,Park, Hyeji,Choe, Heeman,Langdon, Terence G.,Gubicza, Jenő Elsevier 2018 Materials letters Vol.214 No.-
<P><B>Abstract</B></P> <P>An investigation was conducted to evaluate the effect of annealing at different temperatures on the tensile properties of ultrafine-grained 316L stainless steel processed by high-pressure torsion (HPT). A “moderate-temperature” annealing at 740 K resulted in reduced strength and elongation due to the annihilation of mobile dislocations. A “high-temperature” annealing at 1000 K yielded a remarkably good combination of yield strength (∼1330 MPa) and elongation to failure (∼43%) which can be attributed to the almost full reversion of α′-martensite formed during HPT into γ-austenite while the grain size remained very fine with a value of about 200 nm.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 316L steel with a nanocrystalline microstructure was processed by HPT. </LI> <LI> The effect of annealing on the tensile properties was studied. </LI> <LI> Annealing to 740 K yielded a pronounced embrittlement and a strength reduction. </LI> <LI> Annealing to 1000 K led to a good combination of strength and elongation to failure. </LI> <LI> The excellent tensile behavior was caused by the very fine austenitic microstructure. </LI> </UL> </P>
Lubrication Aspects during Single Point Incremental Forming for Steel and Aluminum Materials
Nelson Gil Azevedo,João Sá Farias,Ricardo Pereira Bastos,Pedro Teixeira,João Paulo Davim,Ricardo Jose Alves de Sousa 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
Over the past few years, Single Point Incremental Forming (SPIF) has been mainly studied regarding formability, forming forcesinvolved and the dimensional accuracy achieved in the final product. As in any other metal forming process, the choice of thelubricant depends on the deformation mechanisms that characterize the process, the roughness of the material involved and on theprocess parameters. Despite the recent developments on SPIF, little attention has been paid to the influence of lubricants used duringthe process. This study intends to evaluate the influence of the type of lubricant used in SPIF process, particularly on aluminum 1050and DP780 steel sheets, in what concerns the surface quality of final parts. To do so, tests were performed employing a range ofdistinct lubricants. Roughness tests were conducted to evaluate surface quality. Results show opposite trends for aluminum and steelin the sense that lubricants that guarantee better results in aluminum proved to have worse results in steel and vice-versa.