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      • KCI등재

        The Relationship Between Business Resources, Outside Cooperation, Dynamic Capability, and Performance of Startup Enterprises

        Dong Van VU1,Tai Van PHAM2,Ghi Nha TRAN3,Anh Phuong Thi NGUYEN4,Cong Van NGUYEN5 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.6

        This study seeks to examine the relationship between business resources (through VRIN: Valuable - valuable, Rare - scarce; Inimitable - difficult to adapt, Irreplaceable - hard to replace), dynamic capability, external cooperation, and efficiency of startups operating in the seafood export sector. Research data was collected randomly and conveniently from 250 enterprises in Ba Ria-Vung Tau province, Vietnam, from October 2020 to December 2020. After excluding those ineligible, the remaining 204 enterprises meet the research conditions. With the support of SPSS-AMOS 22 dedicated software, using the 5-step Likert scale and Structural Equation Modeling (SEM), the study conducted analysis steps such as verifying convergence, discriminant value, unidirectional and scale reliability when giving the components correlated freely in the critical model by Confirmatory Factor Analysis (CFA) analysis. Results of the study have shown that the enterprise resource factor - VRIN has a positive impact on dynamic capability, and outside cooperation. However, in contrast to previous studies, we found that the relationship between enterprise resources - VRIN and performance as well as the relationship between dynamics capacity and performance is not clear. This shows that seafood exporters need to promote, exploit and effectively use this precious resource to improve business efficiency.

      • KCI등재

        A two-step design of experiments approach to investigate the simultaneous effects of ion-pairing and chemical enhancers to improve the permeability of lornoxicam in a topical hydrogel patch

        Nguyen Huu-Manh,Duong The-Khang,Nguyen Van-Khuyen,Nguyen Thi-Khanh-Ly,Dong Thi-Hoang-Yen,Nguyen Canh-Hung,Tung Nguyen-Thach 한국약제학회 2024 Journal of Pharmaceutical Investigation Vol.54 No.2

        Purpose A two-step experimental design was used to develop a lornoxicam (LOR)-loaded topical hydrogel patch. We specifically focused on the simultaneous effect of the ion pair formation agent (triethanolamine [TEA]) and the chemical enhancer (cremophor RH40 [RH40]) on flux and conducted physicochemical studies and skin physiology assessments to obtain further information. Methods Drug-in-adhesive patches were fabricated using a micrometer-adjustable film applicator. The applied Design of Experiments (DoE) approach consisted of the Fractional Factorial Resolution V + design and the Central Composite Face design established by the MODDE® 12.0 software. Molecular-level drug-excipient interactions were investigated using infrared (IR) and proton nuclear magnetic resonance (1H NMR) spectroscopy. The effects on skin physiological function was assessed using DermaLab Combo. Results DoE results revealed that TEA enhanced flux by 3.14-fold, whereas RH40 reduced it by 4.62-fold. The addition of RH40 resulted in the disappearance of the proton peak within the region of 12–13 ppm, suggesting competition for hydrogen bonding with LOR between TEA and RH40. The optimized formulation (4% TEA, 0% RH40, and 0.2% Al(OH)3) increased skin hydration by 6.20-fold. Opposing effects of TEA and RH40 on skin elasticity were observed. Conclusion Expected flux and adhesion strength for the optimized formulation were 7.18 μg·cm–2·h–1 and 11.79 mJ, respectively. Our understanding of the conflicting effects of TEA and RH40 has been advanced. The integrated use of the two-step DoE, physicochemical studies, and skin physiology assessments was proven to be effective in elucidating the simultaneous effects of different permeation-modifying strategies on patches, thus having substantial value for the successful execution of future research endeavors.

      • KCI등재

        The Interaction between Labor Productivity and Competitiveness in Vietnam

        Nguyen Thi DONG,Tran Thi Ai DIEM,Bui Thi Hong CHINH,Nguyen Thi Diu HIEN 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11

        This study measures the relationship between labor productivity and national competitiveness. Through the shift- share analysis method, the paper has separated labor productivity into three factors: static shift effect, dynamic shift effect and endogeneous effect. Next, in combination with the Granger causality test, the paper examines the relationship between the factors constituting labor productivity and competitiveness during the period from 2005 to 2017. Research data is collected from General Statistics Office and annual global competitiveness reports. The results show that the interaction between labor productivity with global competitiveness index (GCI) in Vietnam has similar variation. Nevertheless, when separating labor productivity into three effects, this relationship shows more clearly that the impact of labor productivity on GCI scores is mainly caused by endogeneous effect, not by static shift effect or dynamic shift effect. Therefore, in order to improve its competitiveness, Vietnam should focus on a number of solutions: reforming the education system towards developing thinking capacity and creative capacity; fostering industrial manners to create dynamic and flexible workers; building the State with sufficient capacity to implement consistent and transparent policies; formulating policies to attract all economic sectors so that they actively participate in the field of human resource training for the country.

      • KCI등재

        Do Changes in the Exchange Rate Have an Asymmetric Effect on the Trade Balance between Vietnam and Japan?

        Nguyen Quang Dong,Tran Thi Ha,Nguyen Quang Huy 한국국제경제학회 2022 International Economic Journal Vol.36 No.1

        The paper examines the impact of changes in the exchange rate on Vietnam’s trade balance with Japan based on the employment of both aggregate and industry-level data in a set of linear and nonlinear autoregressive distributed lag models. The results from the models indicate a degree of bias in regression when using aggregate data and a linear ARDL approach. Among the 19 industries under consideration, the NARDL model presents different responses to exchange rate movements from 16 industries, which account for 46% of imports and 63% of exports between Vietnam and Japan. Using aggregate data, the model shows that the exchange rate positively affects the Vietnam-Japan trade balance in the case of currency depreciation, whereas currency appreciation has no impact on the trade balance. Thus, it is concluded that the exchange rate is an effective tool to stimulate exports and improve the trade balance between Vietnam and Japan.

      • SCIESCOPUSKCI등재

        Effect of Replacing Soybean Meal with Soya Waste and Fish Meal with Ensiled Shrimp Waste on the Performance of Growing Crossbred Ducks

        Dong, Nguyen Thi Kim,Elwinger, K.,Lindberg, J.E.,Ogle, R. Brian Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.6

        Two experiments were conducted with growing crossbred Super-Meat ducks at the experimental duck farm of Cantho University to evaluate the effects of reducing the proportion of soybean meal (SBM) in a broken rice (BR)-SBM mixture and providing soya waste (SW) ad libitum (Expt. 1), and reducing the proportion of fish meal (FM) in a BR-FM mixture and supplying ensiled shrimp waste (ESW) ad libitum (Expt.2). Both experiments included five treatments, with three replicates and ten growing ducks per replicate. In Expt.1, the five diets were based on BR and five levels of SBM, with SW offered ad libitum. The control diet (SBM25) consisted of 75% BR and 25% SBM, and the other four treatments included SBM levels of 20% (SBM20), 14% (SBM14), 8% (SBM8) and 0% (SBM0) mixed with BR to 100%, and with SW ad libitum. In Expt. 2, the control diet consisted of 86% BR and 14% FM, and the other dietary treatments had FM levels of 11% (FM11), 8% (FM8), 4% (FM4) and 0% (FM0) mixed with BR, and with ESW ad libitum. In Expt. 1, total intakes of dry matter (DM), neutral detergent fiber (NDF), acid detergent fiber (ADF) and metabolizable energy (ME) were higher for birds given SW (p<0.001). Total CP intake was highest on the SBM20 diet, and lowest on the SBM0 diet (p<0.001). Lower daily gain (DG) was found for the SBM0 diet (p<0.01). Carcass weights were higher on the control treatment, with the lowest values on the SBM0 diet (p<0.001). Gizzard weights were higher on diets with high intakes of SW (p<0.05). In Expt. 2, birds with high intakes of ESW (FM4 and FM0) had lower (p<0.01) daily intakes of DM. The total CP intakes declined (p<0.001) with higher intakes of ESW. The highest DG were for the control and FM11 diets, while the lowest value was for diet FM0 (p<0.001). The poorest feed conversion ratio (FCR) was for the FM0 treatment (p<0.01). Lower weights of carcass and breast muscle were found on the FM0 diet (p<0.001). Feed costs per kg gain were only slightly different between diets. However, the lowest feed cost was for ducks on the SBM0 and FM11 diets in Expt.1 and Expt. 2, respectively.

      • KCI등재

        Anti-neuroinfl ammatory effect of oxaline, isorhodoptilometrin, and 5-hydroxy-7-(2¢-hydroxypropyl)-2-methyl-chromone obtained from the marine fungal strain Penicillium oxalicum CLC-MF05

        Dong-Cheol Kim,Tran Hong Quang,Nguyen Thuy Tien,Kwan-Woo Kim,Youn-Chul Kim,Nguyen Thi Thanh Ngan,Nguyen Xuan Cuong,Nguyen Hoai Nam,Hyuncheol Oh 대한약학회 2022 Archives of Pharmacal Research Vol.45 No.2

        Penicillium is a rich source of bioactive compounds. Among all Penicillium species, Penicillium oxalicumhas been reported to produce various types of secondarymetabolites, including alkaloids, phenolics, and tetrahydroxanthonedimeric compounds, exhibiting many pharmacologicaleff ects, such as antiviral, antibacterial, and cytotoxicactivities. Three secondary metabolites were isolated from afermented culture of the sponge-associated fungal strain P. oxalicum CLC-MF05: oxaline ( 1 ), isorhodoptilometrin ( 2 ),and 5-hydroxy-7-(2′-hydroxypropyl)-2-methyl-chromone( 3 ). Their chemical structures were identifi ed by 1D and2D NMR and high-resolution mass spectroscopic analysesand compared with previously reported data. All three compoundsinhibited NO and PGE 2 overproduction and iNOSand COX-2 overexpression in both LPS-stimulated BV2and rat primary microglia. These metabolites also repressed mRNA expression of TNF-α, IL-1β, IL-6, and IL-12. Further,mechanistic studies revealed that the inhibitory actionsof compounds 1–3 were regulated by the inactivation of theNF-κB and MAPK signaling pathways. Furthermore, inactivationof the TLR4/MyD88 pathway contributed to theanti-neuroinfl ammatory activity of these compounds. Theseresults suggest that compounds 1–3 represent potential antiinflammatory candidates for the treatment of neurodegenerativediseases; however, further investigation is needed.

      • KCI등재

        Effects of Supplemental Green LEDs to Red and Blue Light on the Growth, Yield and Quality of Hydroponic Cultivated Spinach (Spinacia oleracea L.) in Plant Factory

        Nguyen Thi Phuong Dung(넨티덩),Tran Thi Thanh Huyen(트란티),Dong Cheol Jang(장동철),Il Seop Kim(김일섭),Nguyen Quang Thach(넨퀸탓) (사)한국생물환경조절학회 2020 생물환경조절학회지 Vol.29 No.2

        본 연구는 폐쇄형 식물공장에서 시금치 수경재배시 세가지의 인공광이 생육, 광합성 및 품질에 미치는 영향을 규명하기 위해 수행되었다. 세가지 광 처리구는 적색 (660nm), 청색 (450nm) 및 녹색 (550nm) LED를 사용하여, R660 / B450 = 4/1 (RBL), R660 / B450 / G550 = 5/2/3 (WWL); R660 / B450 / G550 = 1/1/1 (WL) 비율로 혼합하였고, 동일한 광도로 설정하였다 (PPFD = 190 μmol‧m<SUP>-2</SUP>‧s<SUP>-1</SUP>). 생육조사결과 초장, 엽수는 WL이 가장 적었다. SPAD, 순광합성율, Fv/Fm, LAI, 근권부 생육은 RBL이 가장 높았고 통계적으로 유의하였다. 줄기, 잎, 뿌리의 생체중, 뿌리의 건물 중은 세가지 처리구에서 유의한 차이를 보였다. 대조적으로 WL의 칼륨의 함량은 WWL과 RBL 가운데 가장 높았지만, 반면 칼륨과 철의 함량은 RBL이 가장 높았다. 비타민C 함량도 시험구간 유의한 차이를 보였다. 질소와 옥살산 함량은 WL이 가장 높았고, 용해성 고체와 비타민C 함량은 RBL이 가장 높았다. 옥살산, 질소 함량은 WWL에서 감소하는 경향을 보였고, RBL의 옥살산 함량은 WL와 WWL과 차이가 없었다. 모든 처리구에서 Salmonella, E.coli. 는 감염되지 않았다. 결론적으로, RBL이 시금치의 생육에 적합하지만, 적색, 청색과 적정하게 혼합된 녹색광은 시금치의 생육에 긍정적인 영향을 미친다고 판단된다. The effect of three different light qualities on growth, photosynthesis, quality and safe parameters of hydroponic cultivated spinach (Spinacia oleracea L.) were investigated indoor. Three different light qualities were created of red (660 nm), blue (450 nm) and green (550 nm) LEDs corresponding at ratio R660/B450 = 4/1 (RBL); R660/B450/G550= 5/2/3 (WWL); R660/B450/G550 = 1/1/1 (WL), which were tested at the same intensity (PPFD =190 μmol m-2 s-1). The results showed that the plant height and leaf number were the lowest in WL treatment. The SPAD, Net photosynthesis rate Pn, Fv/Fm, Leaf area index LAI values and all parameters of root characteristics were the highest in RBL treatment and were significantly different from two others. Fresh weight of stem, leaf and root, dry weight of root in the three light qualities were significantly different. In contrast, the highest K<SUP>+</SUP> content in WL was different from WWL and RBL treatments, while Ca<SUP>2+</SUP> and Fe<SUP>2+</SUP> content were the highest in the RBL treatment. Vitamin C content was significantly different between the three treatments. nitrate and oxalic acid contents were the highest in WL treatment, whereas soluble–solids contents and vitamin C contents were the highest in RBL treatment. Oxalic acid, nitrate contents were observed tending reduced under WWL although oxalic acid content in RBL treatment was not different from WL and WWL treatments. In all three different light treatments were not detected Salmonella, E.coli. Our results suggest that RBL may be appropriate light for growth of spinach, but supplementary green light to a combination of red and blue LEDs at the reasonable rate can change the quality of spinach in a positive direction. Hydroponic cultivated spinach was safe for users.

      • SCISCIESCOPUS

        α-Glucosidase Inhibition Properties of Cucurbitane-Type Triterpene Glycosides from the Fruits of <i>Momordica charantia</i>

        Nhiem, Nguyen Xuan,Kiem, Phan Van,Minh, Chau Van,Ban, Ninh Khac,Cuong, Nguyen Xuan,Tung, Nguyen Huu,Ha, Le Minh,Ha, Do Thi,Tai, Bui Huu,Quang, Tran Hong,Ngoc, Tran Minh,Kwon, Young-In,Jang, Hae-Dong,K The Pharmaceutical Society of Japan 2010 Chemical & pharmaceutical bulletin Vol.58 No.5

        <P>Fourteen cucurbitane-type triterpene glycosides (1—14) were isolated from a methanol extract of <I>Momordica charantia</I> fruits, including three new compounds, charantosides A—C (1, 5, 6). Their structures were elucidated by chemical and spectroscopic methods. All isolated compounds were evaluated for α-glucosidase inhibitory effect. Of which, 12 and 13 showed moderate inhibitory activity against α-glucosidase. Whereas, 2, 3, 6—11, and 14 showed weak inhibitory activity, and 1, 4, and 5 were inactive.</P>

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