Predictors of outcomes 3 to 12 months after traumatic brain injury: a systematic review and meta-analysis

Younes Iderdar,Maryem Arraji,Nadia Al Wachami,Morad Guennouni,Karima Boumendil,Yassmine Mourajid,Noureddine Elkhoudri,Elmadani Saad,Mohamed Chahboune 질병관리청 2024 Osong Public Health and Research Persptectives Vol.15 No.1

The exact factors predicting outcomes following traumatic brain injury (TBI) remain elusive. In this systematic review and meta-analysis, we examined factors influencing outcomes in adult patients with TBI, from 3 months to 1 year after injury. A search of four electronic databases—PubMed, Scopus, Web of Science, and ScienceDirect—yielded 29 studies for review and 16 for meta-analysis, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. In patients with TBI of any severity, mean differences were observed in age (8.72 years; 95% confidence interval [CI], 4.77–12.66 years), lymphocyte count (−0.15 109/L; 95% CI, −0.18 to −0.11), glucose levels (1.20 mmol/L; 95% CI, 0.73–1.68), and haemoglobin levels (−0.91 g/dL; 95% CI, −1.49 to −0.33) between those with favourable and unfavourable outcomes. The prevalence rates of unfavourable outcomes were as follows: abnormal cisterns, 65.7%; intracranial pressure above 20 mmHg, 52.9%; midline shift of 5 mm or more, 63%; hypotension, 71%; hypoxia, 86.8%; blood transfusion, 70.3%; and mechanical ventilation, 90%. Several predictors were strongly associated with outcome. Specifically, age, lymphocyte count, glucose level, haemoglobin level, severity of TBI, pupillary reaction, and type of injury were identified as potential predictors of long-term outcomes.

The standard roots for several Egyptian colloquial

Mohamed Moustafa Ahmed Younes 조선대학교 국제문화연구원 2013 국제문화연구 Vol.6 No.2

This paper aimed to study the standard roots for several Egyptian colloquial words through historical comparative prospective, proving that there is a relation between these several words from colloquial in Egypt with the standard Arabic and its old dialects, paying attention to study the way of its developing and the reasons behind that. The paper classified the study material into three sections; nouns, verbs and prepositions. The study aimed to find out the deferent changes which had occurred to the each collective word from Egyptian dialect and the main factors behind that, referring to the similarities and the differences with old dialects from standard Arabic proving that Egyptian dialect is historical extension to all levels from standard Arabic and old Arabic dialects. The most important results for this paper are as following: - proving that there is a tight relation between modern dialect and standard Arabic. - Egyptian dialect got red off the formation accents and instead of it used the discontinuation mark that leaded to changes had occurred to syllable structures in the dialect and the place of stress on the syllable has moved as well. The modern Egyptian dialect got red off teeth`s voices

Methane Oxidation in Landfill Cover Soils: A Review

Mohammed F.M. Abushammala,Noor Ezlin Ahmad Basri,Dani Irwan,Mohammad K. Younes 한국대기환경학회 2014 Asian Journal of Atmospheric Environment (AJAE) Vol.8 No.1

Migration of methane (CH4) gas from landfills to thesurrounding environment negatively affects bothhumankind and the environment. It is thereforeessential to develop management techniques toreduce CH4 emissions from landfills to minimize globalwarming and to reduce the human risks associatedwith CH4 gas migration. Oxidation of CH4 in landfillcover soil is the most important strategy for CH4emissions mitigation. CH4 oxidation occurs naturallyin landfill cover soils due to the abundance of methanotrophicbacteria. However, the activities of thesebacteria are influenced by several controlling factors. This study attempts to review the important issuesassociated with the CH4 oxidation process in landfillcover soils. The CH4 oxidation process is highly sensitiveto environmental factors and cover soil properties. The comparison of various biotic system techniquesindicated that each technique has uniqueadvantages and disadvantages, and the choice ofthe best technique for a specific application dependson economic constraints, treatment efficiency andlandfill operations.

Between Theories of Language and Language Acquisition

Mohamed Moustafa Ahmed Younes 조선대학교 국제문화연구원 2014 국제문화연구 Vol.7 No.2

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Sustained E2 antibody response correlates with reduced peak viremia after hepatitis C virus infection in the chimpanzee

Youn, Jin-Won,Park, Su-Hyung,Lavillette, Dimitri,Cosset, Francois-Loic,Yang, Se-Hwan,Lee, Chang Geun,Jin, Hyun-Tak,Kim, Chang-Min,Shata, Mohamed Tarek M.,Lee, Dong-Hun,Pfahler, Wolfram,Prince, Alfred Wiley Subscription Services, Inc., A Wiley Company 2005 Hepatology Vol.42 No.6

<P>Immune correlates of protection against hepatitis C virus (HCV) infection are not well understood. Here we investigated 2 naive and 6 immunized chimpanzees before and after intravenous challenge, 12 weeks after the last immunization, with 100 50% chimpanzee infectious doses (CID<SUB>50</SUB>) of heterologous genotype 1b HCV. Vaccination with recombinant DNA and adenovirus vaccines expressing HCV core, E1E2, and NS3-5 genes induced long-term HCV-specific antibody and T-cell responses and reduced peak viral load about 100 times compared with controls (5.91 ± 0.38 vs. 3.81 ± 0.71 logs, respectively). There was a statistically significant inverse correlation between peak viral loads and envelope glycoprotein 2 (E2)-specific antibody responses at the time of challenge. Interestingly, one vaccinee that had sterilizing immunity against slightly heterologous virus generated the highest level of E2-specific total and neutralizing antibody responses as well as strong NS3/NS5-specific T-cell proliferative responses. The other four vaccinees with low levels of E2-specific antibody had about 44-fold reduced peak viral loads but eventually developed persistent infections. In conclusion, vaccine-induced E2-specific antibody plays an important role in prevention from nonhomologous virus infection and may provide new insight into the development of an effective HCV vaccine. (HEPATOLOGY 2005;42:1429–1436.)</P>

Linguistic and Pedagogical Aspects of Ibn Khaldoon

( Younes Mohamed ) 한국아랍어아랍문학회 2018 아랍어와 아랍문학 Vol.22 No.4

The aim of this research is to study the linguistic and pedagogical aspects of Ibn Khaldoon's work. Several ideas from Ibn Khaldoon's work show us that he was well ahead of his contemporaries due to his thought and foresight. His ideas on linguistics and education are a valuable source required by all scholars. Ibn Khaldoon theorised that language is a social phenomenon that has come as a result of a number of necessary interactions brought about by a society to allow for a choice and use of speech between individuals. As many scholars accept today, language is a personal acquisition that requires a social branch to appear and develop. As such, Ibn Khaldoon was ahead of other scholars of pedagogy when he confirmed that a strict approach towards pupils is harmful to them, as methods of teaching and its effect on pupils explain to us in detail.

Serum Talin-1 is a Potential Novel Biomarker for Diagnosis of Hepatocellular Carcinoma in Egyptian Patients

Youns, Mahmoud M.,Abdel Wahab, Abdel Hady A.,Hassan, Zeinab A.,Attia, Mohamed S. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

Background: Hepatocellular carcinoma (HCC) is a major cause of cancer mortality worldwide. The outcome of HCC depends mainly on its early diagnosis. To date, the performance of traditional biomarkers is unsatisfactory. Talins were firstly identified as cytoplasmic protein partners of integrins but Talin-1 appears to play a crucial role in cancer formation and progression. Our study was conducted to assess the diagnostic value of serum Talin-1 (TLN1) compared to the most feasible traditional biomarker alpha-fetoprotein (AFP) for the diagnosis of HCC. Methods: TLN1 was detected using enzyme linked immunosorbent assay (ELISA) in serum samples from 120 Egyptian subjects including 40 with HCC, 40 with liver cirrhosis (LC) and 40 healthy controls (HC). Results: ROC curve analysis was used to create a predictive model for TLN1 relative to AFP in HCC diagnosis. Serum levels of TLN1 in hepatocellular carcinoma patients were significantly higher compared to the other groups (p<0.0001). The diagnostic accuracy of TLN1 was higher than that of AFP regarding sensitivity, specificity, positive predictive value and negative predictive value in diagnosis of HCC. Conclusions: The present study showed for the first time that Talin-1 (TLN1) is a potential diagnostic marker for HCC, with a higher sensitivity and specificity compared to the traditional biomarker AFP.

A Comparative Study on Transformational Grammar between Egyptian Dialects and Modern Standard Arabic : A Study on Simple Sentences

Mohamed Moustafa Ahmed Younes(م,ح,م,د,م,ص,ط,ف,ى,أ,ح,م,د,ي,و,ن,س,) 명지대학교 중동문제연구소 2016 중동문제연구 Vol.15 No.3

This paper aims to study transformational grammar in Egyptian dialects and compare it with Modern Standard Arabic(MSA) while highlighting areas of agreement and differences between them. It is also a historical analysis on the development of modern Egyptian dialects, and a clarification of the characteristics of these developments through the study and comparison of the simple sentences in Egyptian dialects and Modern Standard Arabic using examples from the holy Quran and ancient Arabic poetry to verify its authenticity as well as Arab compositions related to the field of modern and ancient Arabic grammar. This study was conducted within a historical and comparative framework to allude to the historical development that took place in these dialects.

아랍 유산 조사에 대한 연구

( Mohamed Moustafa Ahmed Younes ) 한국외국어대학교 중동연구소 2016 중동연구 Vol.35 No.2

Some Arab researchers believe that the art of investigating heritage is a recent topic which was undertaken by contemporary Arab investigators, or those which were learnt from the Orientalists of the current era who slightly preceded them in archeological investigations and their publications. However they were not accurate in this regard as Arab scholars had in fact begun investigating texts since the dawn of Islamic history, and were the first to create rules for this kind of Arab heritage. Those of different fields were also influenced by their style of heritage investigation. Accordingly, much of the current work in investigating texts and publishing them today is a continuation in the work of the great Arab scholars of the past. This study as well as others which have been published in these field are themselves examples of this. In this respect, those who pursue this subject understand the huge effort of the great Arab scholars of the past, and of those who came after them in this field from among the contemporary Arab scholars and Orientalists, in this field of investigating Arab heritage. This study has resulted in the following important findings: Analysing heritage involves the analyst taking great care of the manuscript under analysis in order to assure that all the conditions have been met for confirming its authenticity. Also title of the book under analysis should be correct, as well as the name of the author and the related portion of the book. It is equally necessary to confirm that the text of the book is identical to the image left by the author or at least as close to this as possible. The task of the analyst is to link the text with the reader according to the image that the author would have desired. In addition, mistakes that occur in the text should be left as they are and alluded to in the footnotes with suggestions on possible corrections.

The Origin of Juman Languages

Mohamed Moustafa Ahmed Younes 조선대학교 국제문화연구원 2016 국제문화연구 Vol.9 No.1

This study is concerned with the emergence and evolution of human language, and the differing views and ideas among scientists on this topic. Despite the fact that some of these ideas lack evidence and objectivity, they are still significant to a certain extent. Especially if they are placed in comparison with the acquisition of language in children. This research aims to explore two stages of human language, the first is the creation of mankind and their early activities and interaction with other humans, and secondly at the stage of childhood, when children acquire language from living in a society where a particular language is spoken by the people of that community. This research found the following important results: The emergence of language during childhood goes through particular stages different from those experienced by the first creation of mankind, when language was uttered for the first time, as they go through specific stages of development which most of the world's children experience when first acquiring language. Children then continue to develop their language until the child reaches a stage of stability, where the child utters the language of the community in which he lives only. At this point, acquiring languages other than the language of society around them requires conscious study. In addition to this, there is a clear difference between the development of natural language from the first humans, and the development of language in children who acquire language living in a particular discourse community. [Key words] the emergence of language - human - children - development - tradition - simulation - emotion - social