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Chemical variation in molecular cloud cores in the Orion A cloud. II.
Tatematsu, Ken'ichi,Ohashi, Satoshi,Umemoto, Tomofumi,Lee, Jeong-Eun,Hirota, Tomoya,Yamamoto, Satoshi,Choi, Minho,Kandori, Ryo,Mizuno, Norikazu Astronomical Society of Japan 2014 Publications of the Astronomical Society of Japan Vol.66 No.1
Minamidani, Tetsuhiro,Tanaka, Takanori,Mizuno, Yoji,Mizuno, Norikazu,Kawamura, Akiko,Onishi, Toshikazu,Hasegawa, Tetsuo,Tatematsu, Ken'ichi,Takekoshi, Tatsuya,Sorai, Kazuo,Moribe, Nayuta,Torii, Kazufu American Institute of Physics 2011 The Astronomical journal Vol.141 No.3
<P>In order to precisely determine the temperature and density of molecular gas in the Large Magellanic Cloud, we made observations of the optically thin <SUP>13</SUP>CO(J = 3-2) transition using the ASTE 10 m telescope toward nine peaks where <SUP>12</SUP>CO(J = 3-2) clumps were previously detected with the same telescope. The molecular clumps include those in giant molecular cloud (GMC) Types I (with no signs of massive star formation), II (with H <SPAN CLASS='sml'>II</SPAN> regions only), and III (with H <SPAN CLASS='sml'>II</SPAN> regions and young star clusters). We detected <SUP>13</SUP>CO(J = 3-2) emission toward all the peaks and found that their intensities are 3-12 times lower than those of <SUP>12</SUP>CO(J = 3-2). We determined the intensity ratios of <SUP>12</SUP>CO(J = 3-2) to <SUP>13</SUP>CO(J = 3-2), R<SUP>12/13</SUP><SUB>3-2</SUB>, and <SUP>13</SUP>CO(J = 3-2) to <SUP>13</SUP>CO(J = 1-0), R<SUP>13</SUP><SUB>3-2/1-0</SUB>, at 45'' resolution. These ratios were used in radiative transfer calculations in order to estimate the temperature and density of the clumps. The clumps have a kinetic temperature range of T<SUB>kin</SUB> = 15-200 K and a molecular hydrogen gas density range of n(H<SUB>2</SUB>) = 8 × 10<SUP>2</SUP>-7 × 10<SUP>3</SUP> cm<SUP>–3</SUP>. We confirmed that the higher density clumps have higher kinetic temperature and that the lower density clumps have lower kinetic temperature to better accuracy than in previous work. The kinetic temperature and density increase generally from a Type I GMC to a Type III GMC. We interpret that this difference reflects an evolutionary trend of star formation in molecular clumps. The R<SUP>13</SUP><SUB>3-2/1-0</SUB> and kinetic temperature of the clumps are well correlated with the Hα flux, suggesting that the heating of molecular gas with density n(H<SUB>2</SUB>) = 10<SUP>3</SUP>-10<SUP>4</SUP> cm<SUP>–3</SUP> can be explained by stellar far-ultravoilet photons.</P>
Yoshihisa Arao,Yuichi Sato,Satoru Hashimoto,Hiroki Honda,Kazumi Yoko,Masaaki Takamura,Ken-ichi Mizuno,Masaaki Kobayashi 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.6
A 50-year-old woman had a percutaneous endoscopic gastrostomy (PEG) tube placed after surgery for pharyngeal cancer. After 21 months, the PEG tube was removed due to improvement of per-oral ingestion. She had taken prednisolone for 31 years for systemic lupus erythematosus. The post-PEG fistula did not close spontaneously. The cause of the fistula was slow wound healing and gastrostomy site inflammation due to long-term steroid therapy. We were able to close the fistula with an over-the-scope clipping (OTSC) system. This case suggests that OTSC is useful for closing persistent post-PEG fistulas in patients receiving long-term prednisolone therapy.
Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis
Sato, Chihiro,Takahashi, Kazuya,Sato, Hiroki,Naruse, Takumi,Nakajima, Nao,Takatsuna, Masafumi,Mizuno, Ken-ichi,Hashimoto, Satoru,Takeuchi, Manabu,Yokoyama, Junji,Kobayashi, Masaaki,Terai, Shuji The Korean Gastric Cancer Association 2022 Journal of gastric cancer Vol.22 No.-
Purpose: Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods: A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results: Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs.Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions: Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis.
Endoscopic Findings and Treatment of Gastric Neoplasms in Familial Adenomatous Polyposis
Sato Chihiro,Takahashi Kazuya,Sato Hiroki,Naruse Takumi,Nakajima Nao,Takatsuna Masafumi,Mizuno Ken-ichi,Hashimoto Satoru,Takeuchi Manabu,Yokoyama Junji,Kobayashi Masaaki,Terai Shuji 대한위암학회 2022 Journal of gastric cancer Vol.22 No.4
Purpose Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs. Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis. Purpose Gastric neoplasia is a common manifestation of familial adenomatous polyposis (FAP). This study aimed to elucidate the clinical characteristics, endoscopic features including fundic gland polyposis (FGPsis), and treatment outcomes of gastric neoplasms (GNs) in patients with FAP. Materials and Methods A total of 35 patients diagnosed with FAP, including nine patients from four pedigrees who underwent esophagogastroduodenoscopy (EGD), were investigated regarding patient characteristics, GN morphology, and treatment outcomes. Results Twenty-one patients (60.0%) had 38 GNs; 33 (86.8%) and 5 (13.2%) were histologically diagnosed with adenocarcinoma and adenoma, respectively. There were no specific patient characteristics related to GNs. Nodule-type GNs were more prevalent in patients with FGP than without (52.2% vs. 0.0%, P=0.002) in the upper body of the stomach. Conversely, depressed-type GNs were fewer in patients with FGPsis than in those without (13.0% vs. 73.3%, P<0.001). Slightly elevated-type GNs were observed in both groups (34.8% vs. 20.0%, P=0.538). Even within pedigrees, the background gastric mucosa and types of GNs varied. In total, 24 GNs were treated with endoscopic submucosal dissection (ESD) and eight with endoscopic mucosal resection (EMR). EMR was selected for GNs with FGPsis because of the technical difficulty of ESD, resulting in a lower en bloc resection rate (62.5% vs. 100%, P=0.014). Conclusions Our study indicates the necessity of routine EGD surveillance in patients diagnosed with FAP. Notably, the morphology and location of GNs differed between patients with and without FGPsis. Endoscopic treatment and outcomes require more attention in cases of FGPsis.