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Wireless Sensor Networks for Monitoring the Daily Interactions between User and Objects
Masayuki Nakamura,Masayuki Tsuda,Kazue Takahashi,Jiro Nakamura 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
This article presents a hybrid system of wireless sensor networks and active tags in order to monitor user"sbehaviors of handling objects. The sensor networks consist of an acceleration sensor node that the user carries and occupancy sensor nodes that are deployed in a workplace. The active tags, which are embedded with switch sensors, vibration sensors and occupancy sensors, are attached to objects. The sensor networks capture the user"s movements andthe active tags detect the objects" movements. The sensor nodes have the parent selection function that can allocate resources to the nodes. We demonstrate monitoring the user"s behaviors of handling the objects using the hybrid system.We also show that the proposed system provides the useful information for behavior classification.
Impact of Surgery on Oligometastatic Pancreatic Cancer: Current Status and Future Perspectives
Masayuki Sho,Satoshi Yasuda,Minako Nagai,Kota Nakamura,Taichi Terai,Yuichiro Kohara 대한소화기암연구학회 2023 Journal of Digestive Cancer Research Vol.11 No.1
Pancreatic cancer treatment has advanced. In particular, effective chemotherapy regimendevelopment has fundamentally altered the therapeutic concept and strategy for pancreaticcancer treatment. Consequently, the prognosis of patients with pancreatic cancer has graduallyimproved. Conversion surgery for locally advanced pancreatic cancer may offer long-term survival or even a full recovery in some individuals. In contrast, metastatic pancreatic cancer haslong been considered a surgical contraindication because aggressive surgical resection of themetastatic lesions does not prolong patient survival. Unexpectedly positive benefits of anticancer therapy in recent clinical experience were observed even with metastatic pancreatic cancer. To date, little evidence presented the success of surgical resection for metastatic pancreatic cancer treatment in such rare cases. However, hope and concern are growing that surgical intervention, even in patients with metastatic cancer, may result in favorable outcomes. Several studiessuggested different surgical intervention effects depending on metastasis sites and patterns. Thus, this review summarizes the current status of surgery in the multidisciplinary treatment ofoligometastatic pancreatic cancer and discusses future perspectives.
Masayuki Sekine,Takayuki Enomoto,Masami Arai,Hiroki Den,Hiroyuki Nomura,Takeshi Ikeuchi,Seigo Nakamura 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.4
Objective: and mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) by age 40 and 45, respectively. However, the carriers have a different way of thinking about their life plan. We aimed to investigate the distribution of age at diagnosis of ovarian cancer (OC) patients to examine the optimal timing of RRSO in the carriers. Methods: We examined a correlation between age at diagnosis of OC and common mutation types in 3,517 probands that received genetic testing. Among them, germline mutation (g m), germline mutation (g m) and germline wild-type (g wt) were found in 185, 42 and 241 OC patients, respectively. Results: The average age at diagnosis of OC in g m and g m was 51.3 and 58.3 years, respectively, and the difference from g wt (53.8 years) was significant. Theg m carriers did not develop OC under the age of 40. The average age was 50.1 years for L63X and 52.8 years for Q934X in , and 55.1 years for R2318X and 61.1 years for STOP1861 in . The age at diagnosis in L63X or R2318X carriers was relatively younger than other or carriers, however their differences were not significant. With L63X and R2318X carriers, 89.4% (42/47) and 100% (7/7) of women were able to prevent the development of OC, respectively, when RRSO was performed at age 40. Conclusion: There appears to be no difference in the age at diagnosis of OC depending on the type of common mutation. Further analysis would be needed.
The Effects of MRI on Mouse Embryos During Fetal Stage
Nakamura, Takashi,Ryu, Myung-Sun,Sakazaki, Takahiko,Itokawa, Yuka,Maenaka, Toshihiro,Masubuchi, Takashi,Sekimoto, Hiroyuki,Kanehara, Masayuki,Kang, Young-Nam,Gu, Yeun-Hwa The Korean Association for Radiation Protection 2006 방사선방어학회지 Vol.31 No.2
The effects of Magnetic resonance imaging (MRI) on mouse embryos at the early stage of organogenesis were investigated. Pregnant ICR mice were exposed on day 8 of gestation to MRI at 0.5 T for 0.5 hour to 3 hours. The mortality rates of embryos or fetuses, the incidence of external malformations, fetal body weight and sex ratio were observed at day 18 of gestation. A significant increase in embryonic mortality was observed after exposure to either 0.5 T MRI for 0.5 hour or 2 hours. However, the exposure to MRI for 1 hour or 3 hours did not induce any significant increase in embryonic mortality when compared with control. External malformations such as exencephaly, cleft palate and anomalies of tail were observed in all experimental groups exposed to each MRI. A statistically significant increase of external malformations was observed in all groups treated with 0.5 T MRI for 0.5 hour and 3 hours. The incidence of external malformations in the mice group exposed to 0.5 T MRI for 0.5-hour was found to be higher than those of mice group exposed to 0.5 T MRI for 2 hours. The effects of MRI on the external malformations might not to be dose-dependent. There was no statistically significant difference in fetal body weight and sex ratio among each MRI exposure groups.
Impact of Surgery on Oligometastatic Pancreatic Cancer: Current Status and Future Perspectives
Masayuki Sho,Satoshi Yasuda,Minako Nagai,Kota Nakamura,Taichi Terai,Yuichiro Kohara Korean Society of Gastrointestinal Cancer 2023 Journal of digestive cancer reports Vol.11 No.1
Pancreatic cancer treatment has advanced. In particular, effective chemotherapy regimen development has fundamentally altered the therapeutic concept and strategy for pancreatic cancer treatment. Consequently, the prognosis of patients with pancreatic cancer has gradually improved. Conversion surgery for locally advanced pancreatic cancer may offer long-term survival or even a full recovery in some individuals. In contrast, metastatic pancreatic cancer has long been considered a surgical contraindication because aggressive surgical resection of the metastatic lesions does not prolong patient survival. Unexpectedly positive benefits of anticancer therapy in recent clinical experience were observed even with metastatic pancreatic cancer. To date, little evidence presented the success of surgical resection for metastatic pancreatic cancer treatment in such rare cases. However, hope and concern are growing that surgical intervention, even in patients with metastatic cancer, may result in favorable outcomes. Several studies suggested different surgical intervention effects depending on metastasis sites and patterns. Thus, this review summarizes the current status of surgery in the multidisciplinary treatment of oligometastatic pancreatic cancer and discusses future perspectives.
Soichiro Nakamura,Masayoshi Saito,Tetsuhisa Goto,Hiroki Saeki,Masahiro Ogawa,Masayuki Gotoh,Yasuhide Gohya,Jae-Kwan Hwang 한국식품영양과학회 2000 Preventive Nutrition and Food Science Vol.5 No.2
Hen egg-white lysozyme was conjugated with 7~9 mers xyloglucan hydrolysates (MW=1,400) at 60℃ and 79% relative humidity for 3 days. SDS-PAGE showed that the conjugation between lysozyme and the oligosaccharide began from 1-day incubation, and three molecules of carbohydrate chains were attached to a protein molecule after 3-day incubation. The enzymatic activity of lysozyme was totally conserved in the neoglycoprotein, when measured by using glycol chitin as substrate. Besides, the emulsifying properties of lysozyme were vastly improved by the conjugation with the oligosaccharide, in which emulsifying activity of the neoglycoprotein was five times higher than that of native one.