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      • SCISCIESCOPUS

        A large-area free-standing graphene oxide multilayer membrane with high stability for nanofiltration applications

        Chen, Long,Li, Yanhui,Chen, Lina,Li, Na,Dong, Chenglong,Chen, Qiong,Liu, Beibei,Ai, Qing,Si, Pengchao,Feng, Jinkui,Zhang, Lin,Suhr, Jonghwan,Lou, Jun,Ci, Lijie Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.345 No.-

        <P><B>Abstract</B></P> <P>A flexible and free-standing graphene oxide and nylon 6 (GO@nylon 6) multilayer nanofiltration membrane was prepared by a layer-by-layer assembly process. The combination of electrospinning and electrospraying technique was employed, which can facilely prepare large-area membrane with size of 20 × 30 cm. The mechanical stability of multilayer membrane has enhanced significantly due to the tightly locked structure achieved by nylon 6 nanofibers network. The novel GO@nylon 6–13 multilayer nanofiltration membrane demonstrated a pure water flux up to 11.15 L m<SUP>−2</SUP> h<SUP>−1</SUP> bar<SUP>−1</SUP>, while keeping high organic dye rejection rate (>95% for methylene blue, and >99% for methyl orange). The rejections rate of the Na<SUB>2</SUB>SO<SUB>4</SUB>, NaCl, CuSO<SUB>4</SUB>, and Pb(NO<SUB>3</SUB>)<SUB>2</SUB> were 56.5%, 27.6%, 36.7%, and 18.9%, respectively. Furthermore, GO@nylon 6–13 multilayer nanofiltration membrane also demonstrated a high flux of some common organic solvents (8.4, 5.3, and 0.8 L m<SUP>−2</SUP> h<SUP>−1</SUP> bar<SUP>−1</SUP> for methanol, ethanol, and NMP, respectively), showing excellent chemical stability for separation process in those solvents.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Large-area GO@nylon 6 multilayer nanofiltration membrane was prepared. </LI> <LI> The multilayer structure enhances the mechanical stability. </LI> <LI> The multilayer membrane demonstrates a high water flux. </LI> <LI> The multilayer membrane shows high rejection rate for organic dyes. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Photograph and cross-section SEM image of GO@nylon 6 multilayer nanofiltration membrane, the inset shows the water contact angle.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Identification and characterization of heat shock proteins in a parasitic wasp Chouioia cuneae (Hymenoptera: Eulophidae)

        LiNa Pan,Feng-ZhuWANG,Xin-Yue ZHANG,Yan-Ni ZHAO,Geng-Ping ZHU,Min LI 한국곤충학회 2018 Entomological Research Vol.48 No.3

        Heat shock proteins (HSPs) are known to be induced in response to various stress factors. Although HSPs have been studied in a number of insects, not much is known about HSPs in the natural enemies of insects, especially parasitoids. In this study, we identified and characterized five full‐length HSP genes (Cchsp40, Cchsp60, Cchsp70, Cchsp83, and Cchsp90) from an endoparasitic chalcid wasp, Chouioia cunea, which parasitizes the fall webworm, Hyphantria cunea pupae, a worldwide pest. The expression of Cchsps in response to temperature, pesticide stresses and UV radiation were also investigated by quantitative real‐time polymerase chain reaction (RT‐qPCR). The results showed that all five Cchsps were induced in response to hot and cold temperatures. Four pesticides induced the abundant expression of Cchsp70, Cchsp83 and Cchsp90 while ultraviolet radiation up‐regulated Cchsp40, Cchsp70, Cchsp83 and Cchsp90. These results indicate the different transcriptional profiles of the five different Cchsps in response to various abiotic stresses. The findings of this study provide insights into the response of C. cunea to abiotic stresses and insight into the use of this parasitoid in biological control strategies.

      • A Multi-center Survey of HPV Knowledge and Attitudes Toward HPV Vaccination among Women, Government Officials, and Medical Personnel in China

        Zhao, Fang-Hui,Tiggelaar, Sarah M.,Hu, Shang-Ying,Zhao, Na,Hong, Ying,Niyazi, Mayinuer,Gao, Xiao-Hong,Ju, Li-Rong,Zhang, Li-Qin,Feng, Xiang-Xian,Duan, Xian-Zhi,Song, Xiu-Ling,Wang, Jing,Yang, Yun,Li, Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Objectives: To assess knowledge of HPV and attitudes towards HPV vaccination among the general female population, government officials, and healthcare providers in China to assist the development of an effective national HPV vaccination program. Methods: A cross-sectional epidemiologic survey was conducted across 21 urban and rural sites in China using a short questionnaire. 763 government officials, 760 healthcare providers, and 11,681 women aged 15-59 years were included in the final analysis. Data were analyzed using standard descriptive statistics and logistic regression. Results: Knowledge of HPV among the general female population was low; only 24% had heard of HPV. Less than 20% of healthcare providers recognized sexually na$\ddot{i}$ve women as the most appropriate population for HPV vaccination. There was high acceptance of the HPV vaccine for all categories of respondents. Only 6% of women were willing to pay more than US $300 for the vaccine. Conclusions: Aggressive education is necessary to increase knowledge of HPV and its vaccine. Further proof of vaccine safety and efficacy and government subsidies combined with increased awareness could facilitate development and implementation of HPV vaccination in China.

      • SCIESCOPUSKCI등재

        Beneficial effects of andrographolide in a rat model of autoimmune myocarditis and its effects on PI3K/Akt pathway

        Zhang, Qi,Hu, Li-qun,Li, Hong-qi,Wu, Jun,Bian, Na-na,Yan, Guang The Korean Society of Pharmacology 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.2

        The study is to investigate effects of andrographolide on experimental autoimmune myocarditis (EAM). Lewis rats were immunized on day 0 with porcine cardiac myosin to establish EAM. The EAM rats were treated with either andrographolide (25, 50, 100 mg/kg/day) or vehicle for 21 days. An antigen-specific splenocytes proliferation assay was performed by using the cells from control rats immunized with cardiac myosin. Survival rates, myocardial pathology and myocardial functional parameters (left ventricle end-diastolic pressure, ${\pm}dP/dt$ and left ventricular internal dimension) of EAM rats received andrographolide were significantly improved. Andrographolide treatment caused an decrease in the infiltration of $CD3^+$ and $CD14^+$ positive cells in myocardial tissue. Moreover, andrographolide treatment caused a reduction in the plasma levels of tumor necrosis factor-alpha, interleukin-17 (IL-17) and myosin-antibody, and an increase in the level of IL-10 in EAM rats. Oral administration of andrographolide resulted in the decreased expression of p-PI3K, p-Akt without any change of PI3K and Akt. Further results indicate andrographolide significantly inhibited myosin-induced proliferation in splenocytes, and this effect was inhibited by co-treatment of SC79 (Akt activator). Our data indicate andrographolide inhibits development of EAM, and this beneficial effect may be due to powerful anti-inflammatory activity and inhibitory effect on PI3K/Akt pathway.

      • SCISCIESCOPUS
      • KCI등재

        Research on Keyword-Overlap Similarity Algorithm Optimization in Short English Text Based on Lexical Chunk Theory

        Na Li,Cheng Li,Honglie Zhang 한국정보처리학회 2023 Journal of information processing systems Vol.19 No.5

        Short-text similarity calculation is one of the hot issues in natural language processing research. The conventionalkeyword-overlap similarity algorithms merely consider the lexical item information and neglect theeffect of the word order. And some of its optimized algorithms combine the word order, but the weights arehard to be determined. In the paper, viewing the keyword-overlap similarity algorithm, the short English textsimilarity algorithm based on lexical chunk theory (LC-SETSA) is proposed, which introduces the lexicalchunk theory existing in cognitive psychology category into the short English text similarity calculation for thefirst time. The lexical chunks are applied to segment short English texts, and the segmentation results demonstratethe semantic connotation and the fixed word order of the lexical chunks, and then the overlap similarityof the lexical chunks is calculated accordingly. Finally, the comparative experiments are carried out, and theexperimental results prove that the proposed algorithm of the paper is feasible, stable, and effective to a largeextent.

      • A Improved Algorithm of Quantum Particle Swarm with Fast Convergence

        Zhang Chun-na,Li Yi-ran,Li Jun-feng 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.6

        An improved algorithm of quantum particle swarm with chaos is presented to solve the problem that the traditional particle swarm algorithm is easy to fall into local optimum and converges very slowly. Through analysis the current state of particles in the iteration, to determine and deal with the particle of poor performance, and keep the normal state continue to complete the search optimal solution, which effectively inhibit premature phenomenon of the particles, and improve the overall search ability of particle swarm. At the same time, in order to improve the performance of the algorithm, introducing chaos mechanism, further enhance the search ability of particle. The experiments of benchmark function show that the improved algorithm has obvious advantages compared with the other two algorithms, it has higher stability and accuracy and faster convergence speed at the same time.

      • Clinical Efficacy of Bevacizumab Concomitant with Pemetrexed in Patients with Advanced Non-small Cell Lung Cancer

        Zhang, Yu-Mei,Li, Yong-Qiang,Liu, Zhi-Hui,Liao, Xiao-Li,Liang, Rong,Lin, Yan,Yuan, Chun-Ling,Liao, Si-Na,Liang, Chao-Yong,Li, Qian,Li, Le-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

        Objective: To observe the clinical efficacy of bevacizumab concomitant with pemetrexed in patients with advanced non-small cell lung cancer (NSCLC). Materials and Methods: A total of 72 patients were randomly divided into a combination group (pemetrexed+bevacizumab, n=36) and a pemetrexed group (n=36) and assessed for disease control (CR+PR+SD) after 4-cycles of first-line GP chemotherapy (gemcitabine+cisplatin). Clinical efficacy, progression-free survival time (PFS), overall survival time (OS), overall response rate (ORR), disease control rate (DCR) and rate of adverse responses between two groups were observed and compared. Results: ORR and DCR were 27.8% and 83.4% in combination group, and 16.7% and 69.5% in the pemetrexed group, respectively, but there were no significant differences (P>0.05). PFS in combination group and pemetrexed group were 4.6 months and 3.9 months respectively (P=0.09), whereas OS in the combination group was 14 months, evidently higher than in the pemetrexed group (11 months, P=0.004). Adverse responses in both groups included high blood pressure, bleeding, thrombocytopenia, anemia, elevated transaminase, diarrhea, vomiting and proteinuria, but there were no significant differences (P>0.05). Conclusions: Bevacizumab concomitant with pemetrexed has better clinical efficacy and safety, giving rise to prolonged survival time in patients with advanced NSCLC.

      • Theoretical and Numerical Analysis of 1 : 1 Main Parametric Resonance of Stayed Cable Considering Cable-Beam Coupling

        Zhang, Li-Na,Li, Feng-Chen,Wang, Xiao-Yong,Cui, Peng-Fei Hindawi Limited 2017 Advances In Materials Science And Engineering Vol.2017 No.1

        <P>For the 1 : 1 main parametric resonances problems of cable-bridge coupling vibration, a main parametric resonances model considering cable-beam coupling is developed and dimensionless parametric resonances differential equations are derived. The main parametric resonances characteristics are discussed by means of multiscale approximation solution methods. Using an actual cable of cable-stayed bridge project for research object, numerical simulation analysis under a variety of conditions is illustrated. The results show that when the coupling system causes 1 : 1 parametric resonance, nonlinear main parametric resonances in response are unrelated to initial displacement of the cable, but with the increase of deck beam end vertical initial displacement increases, accompanied with a considerable “beat” vibration. When the vertical initial displacement of deck beam end is 10−6 m order of magnitude or even smaller, “beat” vibration phenomenon of cable and beam appears. Displacement amplitude of the cable is small and considerable amplitude vibration may not occur at this time, only making a slight stable “beat” vibration in the vicinity of the equilibrium position, which is different from 2 : 1 parametric resonance condition of cable-bridge coupling system. Therefore, it is necessary to limit the initial displacement excitation amplitude of beam end and prevent the occurrence of amplitude main parametric excitation resonances.</P>

      • A Hybrid Intelligent Optimization Algorithm of Fast Convergence

        Li Yi-ran,Zhang Chun-na 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.1

        A hybrid intelligent optimization algorithm based on quantum particle swarm is presented to solve the problem that the local search ability of traditional SFLA is poor and converges very slowly. The particle is quantized and introduced chaos mechanism in the algorithm in order to enhance the global search ability, using the escape strategy, the group is divided into three clusters and mutation operation on the cluster within individuals, not only improves the convergence speed and ensure the performance of the algorithm. Experiments show that the improved algorithm has the characteristics of strong optimization capability and performance is improved greatly in whether comparison of the baseline function or analysis of universal database, compared with the other two algorithms have obvious advantages.

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