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      • KCI등재

        Demotivating factors in learning English for elementary school students

        Lee,Jihye,Lee,Chung-Hyun 한국초등영어교육학회 2011 초등영어교육 Vol.17 No.1

        This study aims to identify the demotivating factors in learning English for Korean 5th and 6th graders and determine the differences in the demotivating factors according to students’ gender and English proficiency. For this study, a 57-item questionnaire was constructed based on eight demotivating factors: teachers’ personality and teaching style, class environment, reduced motivation and interest, characteristics of class, difficulty of learning English, negative attitudes toward second language (L2), attitude of group members, and grading and test score. The questionnaire was completed by 170 students, and seven students were then interviewed. The first finding was that reduced motivation and interest, difficulty of learning English, and characteristics of class were the most demotivating factors in respective order. The second finding showed that male students tended to have more negative attitudes toward L2. The third finding was that the lower their proficiency levels were, the more the students attributed their demotivation to reduced motivation and interest, difficulty of learning English, negative attitudes toward L2, attitude of group members, and grading and test score factors. Based on the results, it is suggested that through identifying learners’ demotivating factors, teachers can reduce the causes of demotivation using various methods applicable for the respective demotivating factors.

      • KCI우수등재

        SSP 기후변화 시나리오에 따른 농업용 저수지 홍수조절능력 분석

        김지혜 ( Kim¸ Jihye ),곽지혜 ( Kwak¸ Jihye ),황순호 ( Hwang¸ Soonho ),전상민 ( Jun¸ Sang Min ),이성학 ( Lee¸ Sunghack ),이재남 ( Lee¸ Jae Nam ),강문성 ( Kang¸ Moon Seong ) 한국농공학회 2021 한국농공학회논문집 Vol.63 No.5

        The objective of this study was to evaluate the flood control capacity of the agricultural reservoir based on state-of-the-art climate change scenario - SSP (Shared Socioeconomic Pathways). 18 agricultural reservoirs were selected as the study sites, and future rainfall data based on SSP scenario provided by CMIP6 (Coupled Model Intercomparison Project 6) was applied to analyze the impact of climate change. The frequency analysis module, the rainfallrunoff module, the reservoir operation module, and their linkage system were built and applied to simulate probable rainfall, maximum inflow, maximum outflow, and maximum water level of the reservoirs. And the maximum values were compared with the design values, such as design flood of reservoirs, design flood of direct downstream, and top of dam elevation, respectively. According to whether or not the maximum values exceed each design value, cases were divided into eight categories; I-O-H, I-O, I-H, I, O-H, O, H, X. Probable rainfall (200-yr frequency, 12-h duration) for observed data (1973∼2020) was a maximum of 445.2 mm and increased to 619.1∼1,359.7 mm in the future (2011∼2100). For the present, 61.1% of the reservoirs corresponded to I-O, which means the reservoirs have sufficient capacity to discharge large inflow; however, there is a risk of overflowing downstream due to excessive outflow. For the future, six reservoirs (Idong, Baekgok, Yedang, Tapjung, Naju, Jangsung) were changed from I-O to I-O-H, which means inflow increases beyond the discharge capacity due to climate change, and there is a risk of collapse due to dam overflow.

      • KCI등재후보

        Overseas Digital Citizenship Education Research Analysis and Implications

        JiHye Lee(JiHye Lee) 한국아세아태평양교육문화융복합학회 2022 Asia Pacific Journal of Teaching and Learning Vol.2 No.2

        Purpose The purpose of this study is to examine digital citizenship education in other countries and to suggest future directions for digital citizenship education. Through this, it is intended to provide implications for curriculum revision and subjects related to digital citizenship. Method In order to achieve the purpose of this study, websites, papers, and books were analyzed. In the EU, digital citizenship education presented by the Council of Europe was examined. In the UK, I analyzed the Connected World of the UK Council for Internet Safety. In Australia, I looked at two institutions: the New South Wales Department of Education and the ARC Centre of Excellence for the Digital Child. Common Sense, a nonprofit organization in the US, Smart Media that is a center for digital and media literacy in Canada, and DQ Institute in Singapore were also analyzed. Results Based on the examination of digital citizenship education in other countries, it was found that they emphasize responsibility within the digital society by paying attention to the connectivity of the digital society. For safety in the digital society, education in understanding the digital society and its characteristics is proposed. In addition, the rights within the digital society are considered important in protecting the digital rights of the self and others. Conclusion Since digital use is not limited to schools, education connected with home and society is necessary. For this, digital citizenship education for parents is needed. It is also necessary to recognize the importance of cultivating digital citizenship in society. In addition, it is necessary to develop a variety of educational material and educational programs that can be used in schools, homes, and organizations.

      • Fine-tuning the pore size of mesoporous graphene in a few nanometer-scale by controlling the interaction between graphite oxide sheets

        Lee, Jihye,Nankya, Rosalynn,Kim, Aran,Jung, Hyun Elsevier 2018 ELECTROCHIMICA ACTA Vol.290 No.-

        <P><B>Abstract</B></P> <P>Mesoporous graphene (MG) was successfully synthesized by using the soft-template method with graphite oxide (GO) and triblock co-polymer (P123). The obtained MGs exhibit a high surface area as well as tuned pore parameters by preparing GO/P123 composite gel under different reaction conditions. Freeze-drying of the composite gel leads to physical interaction between the GO sheets, which induced the largest pores in MG. While, hydrothermal treatment can generate the chemical linkage between GOs through various reactions of oxygen functional groups on GOs, it facilitates the formation of relatively smaller and more uniform pores. Especially, the presence of a base catalyst under hydrothermal reaction accelerates the chemical reactions, which causes the smallest and most uniform pores. As controlling the interaction between GOs, the pore size of the MGs was easily fine-tuned in a few nanometer-scales never reported. Herein, the electrochemical performance was preliminarily tested as a supercapacitor among the various applications of MG. As a results, the hydrothermal treated sample shows the highest specific capacitance of 151.8 F g<SUP>−1</SUP> at a current density of 0.1 A g<SUP>−1</SUP>. Additionally, it exhibits excellent cycle stability with ∼96% retention of its initial capacitance at a current density of 3.0 A g<SUP>−1</SUP> even after 5000 cycles.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • One-Step Peptide Backbone Dissociations in Negative-Ion Free Radical Initiated Peptide Sequencing Mass Spectrometry

        Lee, Jihye,Park, Hyeyeon,Kwon, Hyuksu,Kwon, Gyemin,Jeon, Aeran,Kim, Hugh I.,Sung, Bong June,Moon, Bongjin,Oh, Han Bin American Chemical Society 2013 ANALYTICAL CHEMISTRY - Vol.85 No.15

        <P>Peptide dissociation behavior in TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl)-based FRIPS (free radical initiated peptide sequencing) mass spectrometry was analyzed in both positive- and negative-ion modes for a number of peptides including angiotensin II, kinetensin, glycoprotein IIb fragment (296–306), des-Pro<SUP>2</SUP>-bradykinin, and ubiquitin tryptic fragment (43–48). In the positive mode, the ·Bz-C(O)–peptide radical species was produced exclusively at the initial collisional activation of <I>o</I>-TEMPO-Bz-C(O)–peptides, and two consecutive applications of collisional activation were needed to observe peptide backbone fragments. In contrast, in the negative-ion mode, a single application of collisional activation to <I>o</I>-TEMPO-Bz-C(O)–peptides produced extensive peptide backbone fragmentations as well as ·Bz-C(O)–peptide radical species. This result indicates that the duty cycle in the TEMPO-based FRIPS mass spectrometry can be reduced by one-half in the negative-ion mode. In addition, the fragment ions observed in the negative-ion experiments were mainly of the <I>a</I>-, <I>c</I>-, <I>x</I>-, and <I>z</I>-types, indicating that radical-driven tandem mass spectrometry was mainly responsible for the TEMPO-based FRIPS even with a single application of collisional activation. Furthermore, the survival fraction analysis of <I>o</I>-TEMPO-Bz-C(O)–peptides was made as a function of the applied normalized collision energy (NCE). This helped us to better understand the differences in FRIPS behavior between the positive- and negative-ion modes in terms of dissociation energetics. The duty-cycle improvement made in the present study provides a cornerstone for future research aiming to achieve a single-step FRIPS in the positive-ion mode.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2013/ancham.2013.85.issue-15/ac303517h/production/images/medium/ac-2012-03517h_0010.gif'></P>

      • KCI우수등재

        Comparison of students performance of objective structured clinical examination during clinical practice

        Jihye Yu,Sukyung Lee,Miran Kim,Janghoon Lee 한국의학교육학회 2020 Korean journal of medical education Vol.32 No.3

        Purpose: Clinical practice for medical students aims to improve their clinical competency. Since students gain experience in clinical practice, it is assumed that their capacity for care is strengthened. This study aimed to verify whether there is a change in the competency of medical students after clinical practice. Methods: We assessed the clinical performance of 120 medical students who were enrolled in the fifth year over the academic years 2016-2018. Objective structured clinical examination (OSCE) was used to measure the clinical competency. Results: The OSCE scores for November fifth grade improved significantly compared to May fifth grade. The scores in September of sixth grade were slightly lower than those of November of fifth grade, but there was no statistically significant difference. Conclusion: It was confirmed that the clinical practice of fifth-year students improved their clinical competency, but it did not show any significant shift in the clinical competency of sixth-year students. The results of this study suggest that it is very important to organize the curriculum so that students can continue to experience patient-facing care throughout the entire clinical practice course to produce highly qualified physicians.

      • KCI등재

        COVID-19 drugs: potential interaction with ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein

        Lee Jaeok,Kim Jihye,강지연,Lee Hwa Jeong 한국약제학회 2023 Journal of Pharmaceutical Investigation Vol.53 No.2

        Background The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has resulted in acute respiratory distress, fatal systemic manifestations (extrapulmonary as well as pulmonary), and premature mortality among many patients. Therapy for COVID-19 has focused on the treatment of symptoms and of acute inflammation (cytokine storm) and the prevention of viral infection. Although the mechanism of COVID-19 is not fully understood, potential clinical targets have been identified for pharmacological, immunological, and vaccinal approaches. Area covered Pharmacological approaches including drug repositioning have been a priority for initial COVID-19 therapy due to the time-consuming nature of the vaccine development process. COVID-19 drugs have been shown to manage the antiviral infection cycle (cell entry and replication of proteins and genomic RNA) and anti-inflammation. In this review, we evaluated the interaction of current COVID-19 drugs with two ATP-binding cassette transporters [P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP)] and potential drug-drug interactions (DDIs) among COVID-19 drugs, especially those associated with P-gp and BCRP efflux transporters. Expert opinion Overall, understanding the pharmacodynamic/pharmacokinetic DDIs of COVID-19 drugs can be useful for pharmacological therapy in COVID-19 patients.

      • SCIESCOPUSKCI등재
      • KCI등재

        Curcumin and hesperetin attenuate D-galactose-induced brain senescence in vitro and in vivo

        Jihye Lee,Yoo Sun Kim,Eunju Kim,Yerin Kim,Yuri Kim 한국영양학회 2020 Nutrition Research and Practice Vol.14 No.5

        BACKGROUND/OBJECTIVES: Brain senescence causes cognitive impairment and neurodegeneration. It has also been demonstrated that curcumin (Cur) and hesperetin (Hes), both antioxidant polyphenolic compounds, mediate anti-aging and neuroprotective effects. Therefore, the objective of this study was to investigate whether Cur, Hes, and/or their combination exert anti-aging effects in D-galactose (Dg)-induced aged neuronal cells and rats. MATERIALS/METHODS: SH-SY5Y cells differentiated in response to retinoic acid were treated with Cur (1 μM), Hes (1 μM), or a combination of both, followed by 300 mM Dg. Neuronal loss was subsequently evaluated by measuring average neurite length and analyzing expression of β-tubulin III, phosphorylated extracellular signal-regulated kinases, and neurofilament heavy polypeptide. Cellular senescence and related proteins, p16 and p21, were also investigated, including their regulation of antioxidant enzymes. In vivo, brain aging was induced by injecting 250 mg/kg body weight (b.w.) Dg. The effects of supplementing this model with 50 mg/kg b.w. Cur, 50 mg/kg b.w. Hes, or a combination of both for 3 months were subsequently evaluated. Brain aging was examined with a step-through passive avoidance test and apoptosis markers were analyzed in brain cortex tissues. RESULTS: Cur, Hes, and their combination improved neuron length and cellular senescence by decreasing the number of β-gal stained cells, down-regulated expression of p16 and p21, and up-regulated expression of antioxidant enzymes, including superoxide dismutase 1, glutathione peroxidase 1, and catalase. Administration of Cur, Hes, or their combination also tended to ameliorate cognitive impairment and suppress apoptosis in the cerebral cortex by downregulating Bax and poly (ADP-ribose) polymerase expression and increasing Bcl-2 expression. CONCLUSIONS: Cur and Hes appear to attenuate Dg-induced brain aging via regulation of antioxidant enzymes and apoptosis. These results suggest that Cur and Hes may mediate neuroprotective effects in the aging process, and further study of these antioxidant polyphenolic compounds is warranted.

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