휠체어 디자인 특성에 따른 효율의 차이 규명

임비오,문영진,은선덕 한국운동역학회 2003 한국운동역학회지 Vol.13 No.1

Lim, B-O · Moon, Y-J and Eun, S-D. Analysis on the differences of mechanical efficiency from design characteristics of wheelchair. Korean Journal of Sport Biomechanics Vol. 13, No. 1,pp. 109-119.'2003 Korean Society of Sport Biomechanics proceedings. The purpose of this study was to investigate differences of the mechanical efficiency of the characteristics of the basketball wheelchairs(cambers & size of the handrims). Nine mechanical efficiency on the characteristics of the basketball wheelchairs(cambers 7 size of the handrims). Nine healthy and normal wheelchair basketball players who had no impairments to their upper extremities were volunteered to participate in this study. VO_2 was collected using automatic gas analyzer(vmax29). Gross efficiency, net efficiency and work efficiency were analyzed from the calculated external power output and energy expenditure. The results were followed. First, gross efficiency in the basketball wheelchairs was observed across the range form 4 to 10%. Gross efficiency in this study showed less values than that from the literature reviewed in the arm cranking(15%), racing wheelchair(above 30%), gait(27%) and cycling(18-23%). Second, the small size of handrim(61cm) at the 16 degrees of camber produced higher efficiency values than the large size of handrim(66cm) whereas the different sizes of handrim at the 20 degrees of camber did not show any pattern. Third, both faster speed(1.11㎧→1.39㎧) and increase in treadmill inclination produced increases in energy expenditure. The results of this study may provide not only better understanding of the mechanical efficiency with adequate camber degree and proper size of handrim but also fundamental information for manufacturing the wheelchair.

KF114와 KB108 원료가공업의 연기증 Nicotine 및 Tar 함량의 변화

이철희,임흥빈,신주식,석영선 충북대학교 연초연구소 2004 煙草硏究 Vol.19 No.-

궐련담배 연기 중 Tar와 Nicotine 함량은 대부분의 국가에서 담배 포갑지에 표시하도록 규정하고 있으며 우리나라에서도 2003년부터 시행하고 있다. 그리하여 궐련담배 제품의 설정목표에 따라 엽배합의 방안을 강구하고자 우리나라에서 생산하고 있는 황색종과 버어리종의 주 품종인 KF114와 KB108의 원료 가공엽을 김천원료공장과 남원료공장에서 착엽위치 및 등급별로 채취하여 연기 중 Nicotine, Tar 및 CO 함량을 조사하였으며, 그 결과를 요약하면 다음과 같다. 1. 원료엽 중 니코틴 함량은 황색종 KF114에 비하여 버어리종 KB108이 높고, 본엽과 상엽에서는 등급이 낮을수록 함량이 높고, 중엽과 하엽에서는 등급이 낮을수록 함량이 낮았다. 2. 황색종 KF114는 궐련담배 1개비 당 중량이 본엽, 중엽, 상엽, 하엽 순으로 무거웠고, 엽위별 등급간에는 등급이 높을수록 무거웠다. 연소시간과 흡연회수는 본엽, 상엽, 중엽, 하엽 순으로 길고 많았다. 3. 버어리종 KB108은 궐련담배 1개비 당 중량이 상엽, 본엽, 중엽, 하엽 순으로 무거웠고, 엽위별 등급간에는 등급이 높을수록 무거웠다. 연소시간은 상엽, 본엽, 중엽, 하엽 순으로 길었으며, 중엽과 하엽에서는 등급이 높을수록 본엽과 상엽에서는 등급이 낮을수록 길었다.4. 황색종 KF114 원료 가공엽의 연기 중 니코틴과 타르 함량은 본엽에서는 등급이 낮을수록 높고, 중엽과 하엽에서는 등급이 높을수록 높은 값을 나타냈다. CO 함량은 본엽, 중엽, 상엽, 하엽순으로 많았고, 등급간 차이는 니코틴과 타르 함량에 대한 등급간 차이보다 적었다. 5. 버어리종 KB108 원료 가공엽의 연기 중 니코틴과 타르 함량은 상엽과 본엽에서는 등급이 낮을수록 높고, 중엽과 하엽에서는 등급이 높을수록 높은 값을 나타냈다. CO의 함량은 상엽, 본엽, 중엽, 하엽 순으로 높았고, 엽위 별 등급간에 차이가 없었다. 6. 잎담배 종류 및 가공엽의 등급에 따라 nicotine/tar 및 Co/tar 비율에 차이가 있는 것을 알 수 있으며, 엽위가 낮을수록 비율도 감소하였다. 7. 버어리종 KB108는 흡연회수, 니코틴, 타르및 CO가 각각 정의 상관관계가 인정되었으나, 황색종 KF114에서는 CO와 니코틴, CO와 타르 간에는 상관관계가 없었다. In most countries, nicotine and tar contents of cigarette smoke should be represented on the cigarette pack by law. It has been carrying out in Korea from 2003. In order to control those contents, It was tested the contents of tar, nicotine, carbon monoxide (CO) of smoke components and puff number for blending two major varieties produced in Korea, KF114, a flue-cured, and KB108, a burley. The processed leaf tobacco were taken from Kim-cheon and Ock-cheon leaf tobacco processing factory. The results were summarized as followed ; 1. Nicotine contents of processed leaf tobacco were higher in KB108, a burley, than in KF114, a flue-cured. Nicotine contents of leaf and tips were higher in low-grade leaves than in high-grade leaves, but those of cutters and lugs were lower in low-grade leaves than in high-grade leaves. 2. The weight per cigarette of KF114 was heavier in the order of leaf, cutters, tips and lugs, and was heavier in high-grade leaves than in low-grade leaves. Combustion time was longer and puff number was more in the order of leaf, tips, cutters and lugs. 3. The weight per cigarette of KB108 was heavier in the order of tips, leaf, cutters and lugs, and was heavier in high-grade leaves than in low-grade leaves. Combustion time was longer in the order of tips, leaf, cutters and lugs. The time of cutters and lugs was longer in high-grade leaves than in low-grade leaves, but those of leaf and tips was longer in low-grade leaves than in high-grade leaves. 4. Nicotine and tar contents of the smoke from the processed leaf tobacco of KF114 were higher in low-grade leaf than in high-grade leaf and cutters and lugs were higher in high-grade than in low-grade. CO contents were higher in the order of leaf, cutters, tips and lugs. The difference of CO contents between different grades was lower than that of nicotine and tar contents. 5. In nicotine and tar contents of the smoke from the processed leaf tobacco of KB108, leaf and tips were higher in low-grade than in high-grade and cutters and lugs were higher in high-grade than in low-grade. CO contents were higher in the order of tips, leaf, cutters and lugs. There was no significant difference of CO contents between different grades of the stalk position. 6. Nicotine/Tar and CO/Tar ratios showed significant difference according to tobacco variety and grade of processed leaf tobacco. The ratios were reduced in lower stalk position. 7. There were positive correlations between puff number, nicotine, tar and CO contents in KB108, but there were no correlations between CO and nicotine, or CO and tar in KF114.

Rotary type과 linear type 자동흡연 장치에 따른 담배연기 중 타르, 니코틴 및 일산화탄소의 함량 비교

정재훈,김영신,임흥빈,석영선,신주식,이학수 충북대학교 연초연구소 2004 煙草硏究 Vol.19 No.-

본 실험은 type별 흡연 장치의 담배 주류연 포집에 대한 차이를 비교하고자 주류연 중 일반적인 다량의 성분을 측정하였다. 1. 니코틴 함량은 대체로 linear-type 흡연 장치에서 높은 경향 이였으나 유의한 차이는 없었다. 2. 수분 함량은 두 가지 type 간에 유의한 차이는 없었다. 3. tar 함량은 저 농도에서 linear-type 보다 otary-type 흡연 장치가 높은 경향 이였으나 유의한 차이는 없었다. 4. 일산화탄소는 rotary-type과 linear-type 모두 유의한 차이는 없었다. 본 실험결과 ISO 표준 흡연 조건에서 담배 주류연의 tar, 니코틴, 일산화탄소 함량의 측정은 흡연 장치의 type별 통계적으로 유의한 차이는 없는 것으로 판단된다. This study was conducted to compare rotary-type with linear-type automatic smoking machine referred to ISO 3308 in the determination of tar, nicotine and CO in cigarette smoke. Sample were used with 4 kinds of domestic branded cigarettes(tar ; 1, 3, 6, 10 mg/cig) and CORESTA Monitor 4 cigarettes(tar ; 14 mg/cig). Tar and nicotine contents were analysed by gas-chromatograph methods in accordance with ISO 4387 and 10315-1. Determination of carbon monoxide in the vapour phase of cigarette smoke was meaured by NDIR method in ISO 8454. Sample preparation were performed in conditioning room at 22℃, 60 % for 48 hours according to ISO 3402. There was no significant difference between two smoking machine from 1 mg/cig to 14 mg/cig tar cigarettes, but, the contents of three components measured by rotary type showed higher tendency than those by linear type in the case of hight tar cigarettes. The results were the opposite in low tar cigarettes.

Original Articles : Effects of Hydrolysis Time on the Molecular Weight Distribution of Alginates Prepared from Sea Tangle Laminaria japonicus

( Yeong Seon Lim ),( Byeong Jin You ) 한국수산학회 2005 Fisheries and Aquatic Sciences Vol.8 No.3

Effects of cooking methods on trypsin inhibitor contents of shellfish produced in the East coast

Lim Yeong-Seon,Yoo, Byung-JIn 한국수산과학회 양식분과 2018 한국수산과학회 양식분과 학술대회 Vol.2018 No.5

Limocitrin Suppresses Breast Cancer Through Inducing Apoptotic-Cell Death Signaling and Inhibiting the PI3K/AKT/mTOR/S6K Cell Survival Signaling

Yeong-Seon Won,Seung-Jae Lee,Hyung-Jin Lim,Jaehoon Bae,Seon Gyeong Bak,Nisansala Chandimali,Eun Hyun Park,Sang-Ik Park,Hirofumi Tachibana 한국식품영양과학회 2023 Journal of medicinal food Vol.26 No.10

The discovery of limocitrin in Sedum sarmentosum Bunge, a compound known for its potent antitumor activity, hassparked interest in understanding its molecular mechanisms and bioactive effects. Breast cancer, particularly triple-negative breastcancer (TNBC), presents a challenging prognosis with a higher likelihood of recurrence, metastasis, and lower survival ratescompared tomost other cancer types. This study aimed to explore the anticancer potential of limocitrin on two different human breastcancer cell lines. The results of the study revealed that limocitrin effectively reduced the viability of breast cancer cells, with IC50values of 29.33 – 0.010 and 28.70 – 0.030 lM for MDA-MB-231 and MCF-7 cells, respectively. Further investigations demonstratedthat limocitrin induced apoptotic cell death, characterized by an increase in the population of apoptotic cells and the formationof apoptotic bodies. Limocitrin induced the upregulation of apoptosis-related protein expressions such as apoptosis-inducing factor,Bax, endonuclease G, and cleaved-poly ADP-ribose polymerase, while downregulating the expression of proteins associated withcell survival, including Akt, Bcl-2, Bid,mTOR, PI3K, procaspases, and p70 S6 kinase.Notably, the response to limocitrin treatmentvaried between the two types of breast cancer cells, indicating a differential effect of limocitrin on the intracellular signalingpathways related to cell survival in breast cancer.These findings open up avenues for further research and exploration of limocitrin asa potential therapeutic agent for breast cancer treatment, especially for challenging subtypes like TNBC.

Effects of Hydrolysis Time on the Molecular Weight Distribution of Alginates Prepared from Sea Tangle Laminaria japonicus

Lim Yeong-Seon,You Byeong-Jin The Korean Society of Fisheries and Aquatic Scienc 2005 Fisheries and Aquatic Sciences Vol.8 No.3

To prepare oligouronic acids from high-molecular-weight alginates, sea tangle Laminaria japonicus alginates were hydrolyzed at $80^{\circ}C$ for various hydrolysis times (HT). The effects of hydrolysis time on the distribution ratios (DR) of the molecular weights (MW) of the hydrolyzed alginates were in-vestigated. As HT increased, the DR of the alginates with MW>500 kDa decreased ex-ponentially, while those with MW=50-100 kDa or MW<50 kDa increased exponentially. For MW=300-500 kDa, DR increased exponentially until HT reached 60 min, and then decreased exponentially. Similarly, for MW=100-300 kDa, DR increased exponentially until HT reached 90 min, and then decreased.

정어리액젓의 숙성 중 성분변화

임영선 ( Yeong Seon Lim ),유병진 ( Byeong Jin You ),조영제 ( Young Je Cho ) 한국수산과학회 2002 한국수산과학회지 Vol.35 No.6

정어리 액젓을 재래식 방법으로 18개월 동안 숙성시키면서 2~3개월 간격으로 성분변화에 대하여 조사하였다. 정어리 육의 가수분해도는 숙성 5개월까지는 44%로 큰 폭으로 증가하였으나, 그 이후에는 분해속도가 둔화되어 숙성 18개월 후에는 약 64%의 질소화합물이 육으로부터 액으로 이행되었다. 액젓 중의 총 질소 및 아미노태 질소함량, 그리고 ATP 관련물질 총량은 숙성기간에 비례하여 증가하였으며, 숙성 6개월 이후 ATP 관련물질은 거의 대부분 (75~87%)이 Hx와 요산이었다. HxR+Hx 함량과 요산량이 교차하는 숙성 13.9개월 부근은 61%의 높은 분해율을 보여 경제적인 출하시점으로 판단된다. 18개월간 숙성시킨 정어리 액젓의 유리아미노산 총량은 6,870.7 mg/100mL로 원료 육 총 아미노산 함량 (23,249 mg/100g)의 약 30% 정도였으며, 주요 아미노산은 glutamic acid (18.2%), aspartic acid (10.4%), lysine (8.7%), alanine (8.5%), threonine (6.1%) 등의 순이었다. To investigate changes of components in salt-femented sardine, Sardinops melanostictus sauce during 18 months fermentation, various chemical properties were examined at 2~3 months intervals. The degree of hydrolysis increased sharply until 5 months of fermentation and showed the gentle increasement after that. On the other hand, the contents of total and amino nitrogens, total ATP related compounds increased gradually during 18 months of fermentation. The hypoxanthine and uric acid were abundant in ATP related compounds, ranging from 75% to 87%. The contents of inosine+hypoxanthine and uric acid were crossed at 13.9 months of fermentation. After 18 months of fermentation, sauce was rich in free amino acids, glutamic acid, aspartic acid, lysine, alanine, threonine in that order.

다시마 Laminaria japonicus 알긴산의 분자량 분포에 미치는 가수분해 온도의 영향

임영선 ( Yeong Seon Lim ),유병진 ( Byeong Jin You ) 한국수산과학회 2007 한국수산과학회지 Vol.40 No.4

다시마 (Laminaria japonica) 알긴산의 분자량 분포에 미치는 가수분해 pH의 영향

임영선 ( Yeong Seon Lim ),유병진 ( Byeong Jin You ) 한국수산과학회 2006 한국수산과학회지 Vol.39 No.4