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Validity and Reliability of Metacognitive Rating Scale for Nursing Students
( Lee¸ Kyunghee ),( Heo¸ Youngjin ),( Han¸ Mihwa ),( Kim¸ Mijung ),( Choi¸ Hyunseok ) 한국정신간호학회 2021 정신간호학회지 Vol.30 No.3
Purpose: The aim of this study was to determine the reliability and validity of the metacognition rating scale (MCRS), which is a revised version of the existing metacognition questionnaire (MCQ) with anger and anxiety added. Methods: A survey was conducted on 591 nursing students at colleges in North and South Gyeongsang Provinces, South Korea. The collected data were processed for the reliability and validity of the MCRS through Cronbach’s α and confirmatory factor analysis using SPSS 26.0. Results: Cronbach’s α for the reliability of MCRS was calculated at .88, .86, .77, .74, and .66 for five subfactors. Among the five subfactors, the first, second, third, and fifth factors showed high correlation in each of six items. Factor 4 was highly correlated in 5 out of 6 questions. Conclusion: The data confirm that the MCQ revised to include anger and anxiety is both reliable and valid for nursing students. Therefore, this scale can be used to identify the maladaptive metacognition of nursing students in stressful situations.
지역사회에서 형성된 사회적 지지와 근로자의 사회심리적 스트레스간의 관련성
임화영,김형수,최영환,장성훈,이건세,정최경희,오원기,최재욱,정춘화 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4
Objective: This study was performed to examine the relationship between community-based social support and psychosocial distress in workers. Methods: The study subjects were 596 workers recruited from 11 companies in Chungju city. A structured questionnaire was used to assess sociodemographics, health-related behaviors, job characteristics, job stress, work-based social support, community-based social support and level of psychosocial distress. Results: Hierarchical multiple regression analysis showed that workers with no chronic disease, exercise and sufficient sleep had a higher score of psychosocial distress than those with chronic disease, no exercise, and not enough sleep. Coworker's work-based social support and community-based social support were negatively associated with psychosocial distress. The R square value of total independent variables on psychosocial distress was 0.409, and that of community-based social support on psychosocial distress was 0.052. Conclusion: This study showed that community-based social support served as a protective factor against psychosocial distress in some workers. We recommend the establishment of a worksite stress reduction program in occupational level as well as community-based social support.
Kim, Hyunsoo,Kim, Han-Jong,Lee, Kyunghee,Kim, Jin-Man,Kim, Hee Sun,Kim, Jae-Ryong,Ha, Chae-Myeong,Choi, Young-Keun,Lee, Sun Joo,Kim, Joon-Young,Harris, Robert A,Jeong, Daewon,Lee, In-Kyu Blackwell Publishing Ltd 2012 Journal of cellular and molecular medicine Vol.16 No.2
<P><B>Abstract</B></P><P>Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality. Although several reports have implicated mitochondrial dysfunction in cardiovascular disease and chronic kidney disease, little is known about the potential role of mitochondrial dysfunction in the process of vascular calcification. This study investigated the effect of α-lipoic acid (ALA), a naturally occurring antioxidant that improves mitochondrial function, on vascular calcification <I>in vitro</I> and <I>in vivo</I>. Calcifying vascular smooth muscle cells (VSMCs) treated with inorganic phosphate (Pi) exhibited mitochondrial dysfunction, as demonstrated by decreased mitochondrial membrane potential and ATP production, the disruption of mitochondrial structural integrity and concurrently increased production of reactive oxygen species. These Pi-induced functional and structural mitochondrial defects were accompanied by mitochondria-dependent apoptotic events, including release of cytochrome <I>c</I> from the mitochondria into the cytosol, subsequent activation of caspase-9 and -3, and chromosomal DNA fragmentation. Intriguingly, ALA blocked the Pi-induced VSMC apoptosis and calcification by recovery of mitochondrial function and intracellular redox status. Moreover, ALA inhibited Pi-induced down-regulation of cell survival signals through the binding of growth arrest-specific gene 6 (Gas6) to its cognate receptor Axl and subsequent Akt activation, resulting in increased survival and decreased apoptosis. Finally, ALA significantly ameliorated vitamin D<SUB>3</SUB>-induced aortic calcification and mitochondrial damage in mice. Collectively, the findings suggest ALA attenuates vascular calcification by inhibiting VSMC apoptosis through two distinct mechanisms; preservation of mitochondrial function <I>via</I> its antioxidant potential and restoration of the Gas6/Axl/Akt survival pathway.</P>
Lee, Kyunghee,Kim, Hyunsoo,Kim, Jin-Man,Kim, Jae-Ryong,Kim, Keuk-Jun,Kim, Yong-Jin,Park, Se-Il,Jeong, Jae-Ho,Moon, Young-mi,Lim, Hyun-Sook,Bae, Dong-Won,Kwon, Joseph,Ko, Chang-Yong,Kim, Han-Sung,Shin, Blackwell Publishing Ltd 2011 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol.15 No.10
<P>Systemic transplantation of adipose-derived stem cells (ASCs) is emerging as a novel therapeutic option for functional recovery of diverse damaged tissues. This study investigated the effects of systemic transplantation of human ASCs (hASCs) on bone repair. We found that hASCs secrete various bone cell-activating factors, including hepatocyte growth factor and extracellular matrix proteins. Systemic transplantation of hASCs into ovariectomized mice induced an increased number of both osteoblasts and osteoclasts in bone tissue and thereby prevented bone loss. We also observed that conditioned medium from hASCs is capable of stimulating proliferation and differentiation of osteoblasts <I>via</I> Smad/extracellular signal-regulated kinase (ERK)/JNK (c-jun NH<SUB>2</SUB>-terminal kinase) activation as well as survival and differentiation of osteoclasts <I>via</I> ERK/JNK/p38 activation <I>in vitro</I>. Overall, our findings suggest that paracrine factors secreted from hASCs improve bone repair and that hASCs can be a valuable tool for use in osteoporosis therapy.</P>
Kim, Kyunghee,Kim, Jeongtae,Min, Junhong,Ryu, Sungmin Korean Marketing Association 2017 ASIA MARKETING JOURNAL Vol.19 No.1
Despite the importance of the impact of network structure on the relationships between firms and firm performance, few studies have investigated these effects. This study investigates how network openness influences the relationships between TSI, opportunism, technological uncertainty, and supplier performance. We also try to figure out how network openness functions as a governance mechanism.
Technik und Risiko im kulturwissenschaftlichen Diskurs
Kim, Kyunghee(김경희) 한국카프카학회 2017 카프카연구 Vol.0 No.37
산업사회와 뉴미디어가 출현하면서 형성된 개념인 기술문화는 현대인의 삶을 특징 짓고 인간사를 이해하는 주요 키워드가 되었다. 따라서 문화의 변동은 곧 기술의 변동으로 볼 수 있다. 인간사회에서 일어나는 자연재해와 외부로부터의 위험의 불확실성을 제거하기 위한 ‘도구’로서의 기술은 현대사회에 와서는 계산가능하고 결정에 종속적이고 통제 가능한 리스크의 특성을 지닌 존재로 변화하였다. 따라서 물리적이고 도구적인 분야로 경도된 기술에 대한 전반적인 이해는 문화학 담론의 틀 속에서 다학제적으로 그리고 통합적으로 이루어져야 한다. 기술 제어의 불확실한 가능성과 기술발달의 결과가 아닌 그 과정에 주목한다는 점은 현대의 기술문화가 대립적인 여러 요소들이 상호종속적으로 얽혀서 역동적으로 움직이는, 불확정성이 ‘내재화’된 리스크에 놓여있다는 것을 뜻한다. 근대사회의 근간을 이루고 있던 주체와 객체, 문화와 자연, 물질문명과 정신문명이라는 전형적인 이분법적인 사고를 넘어선 오늘날의 기술은 자연, 사회, 정치, 문화의 망으로 얽혀진 일종의 복합체로서 여러 분야의 경계를 넘나드는 상호문화성의 특징을 지니고 있다. 중간자로서의 기술은 분리된 간극 사이에서 유희하며 물질적 기술과 인간의 정신적 의미형성을 이어주는 교각의 역할을 하고 있으며, 인간의 종속물로서의 기술의 도구적 측면이나 기술결정론의 대립구조가 아닌, 리스크를 함유한 상호문화성이 구성되는 공간을 지속적으로 만들어내고 있다.
Genome-Wide Association Study of Lung Cancer in Korean Non-Smoking Women
Kim, Jin Hee,Park, Kyunghee,Yim, Seon-Hee,Choi, Jin Eun,Sung, Jae Sook,Park, Ju-Yeon,Choi, Yi Young,Jeon, Hyo-Sung,Park, Jae Yong,Yoon, Hyoung Kyu,Kim, Yeul Hong,Yoo, Byung Su,Kim, Young Tae,Hu, Hae-J The Korean Academy of Medical Sciences 2013 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.28 No.6
<P>Lung cancer in never-smokers ranks as the seventh most common cause of cancer death worldwide, and the incidence of lung cancer in non-smoking Korean women appears to be steadily increasing. To identify the effect of genetic polymorphisms on lung cancer risk in non-smoking Korean women, we conducted a genome-wide association study of Korean female non-smokers with lung cancer. We analyzed 440,794 genotype data of 285 cases and 1,455 controls, and nineteen SNPs were associated with lung cancer development (<I>P</I> < 0.001). For external validation, nineteen SNPs were replicated in another sample set composed of 293 cases and 495 controls, and only rs10187911 on 2p16.3 was significantly associated with lung cancer development (dominant model, OR of TG or GG, 1.58, <I>P</I> = 0.025). We confirmed this SNP again in another replication set composed of 546 cases and 744 controls (recessive model, OR of GG, 1.32, <I>P</I> = 0.027). OR and <I>P</I> value in combined set were 1.37 and < 0.001 in additive model, 1.51 and < 0.001 in dominant model, and 1.54 and < 0.001 in recessive model. The effect of this SNP was found to be consistent only in adenocarcinoma patients (1.36 and < 0.001 in additive model, 1.49 and < 0.001 in dominant model, and 1.54 and < 0.001 in recessive model). Furthermore, after imputation with HapMap data, we found regional significance near rs10187911, and five SNPs showed <I>P</I> value less than that of rs10187911 (rs12478012, rs4377361, rs13005521, rs12475464, and rs7564130). Therefore, we concluded that a region on chromosome 2 is significantly associated with lung cancer risk in Korean non-smoking women.</P>