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Activation of the Prefrontal Area Observed by fNIRS
Akemi Kariya,Yoshino Tatsumi,Satoshi Imaizumi 한국노인복지학회 2011 International Journal of Welfare for the Aged Vol.25 No.-
Hospitalization of elderly patients has been increasing in Japan. Management of delirium including hallucination and auditory hallucination after surgery and before and after treatment is important in many of these patients. However, caregivers currently can only use frequent talking to a patient, confinement, monitoring and medication to care for patients with these symptoms. The objective of this study was to collect basic data in order to develop a preventive intervention program before elderly patients develop delirium. Cerebral blood flow in the prefrontal area and temporal lobe was measured using a near-infrared functional neuroimaging system. The balance between the sympathetic and parasympathetic nerves was evaluated as a physiological index by analysis of pulse wave frequency using a continuous blood pressure measurement device. Activation of cerebral blood flow was observed in the prefrontal area while shaking hands. The parasympathetic nerve was dominant in the process of shaking hands, suggesting a relaxing effect.
Akemi Kariya 한국노인복지학회 2011 International Journal of Welfare for the Aged Vol.25 No.-
In Japan, the number of patients with respiratory diseases has increased as society has rapidly aged. Complications, ranging from dysphagia to pneumonia, are common at the end of life in the elderly and often lead to death. Therefore, maintaining respiratory function is a major goal for maintaining the health of the elderly. The purpose of this study was to test whether a breathing technique using a traditional fukimodoshi, a Japanese-style party blower, can prevent deterioration of respiratory function. The study was conducted on elderly people participating in preventive care classes and consisted of a 2-month interventional study using fukimodoshi. Respiratory function was evaluated by monitoring SpO2, respiratory rate, expiratory endurance test and variations in respiratory function observation. In addition, the outcomes of ADL (B.I), V.I, and SF-36 were measured after the procedures. The results showed that the subjects were able to lead their lives with more stability as well as mentally and physically status.
The role of lymphatic interventional radiology for postoperative lymphorrhea
Shuji Kariya,Shintaro Yamamoto,Miyuki Nakatani,Yasuyuki Ono,Takuji Maruyama,Noboru Tanigawa 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.4
Lymphorrhea after gastrointestinal surgery may be treated conservatively or surgically, and treatment by lymphatic interventional radiology has also recently come into use. From pedal lymphangiography, intranodal lymphangiography was widely adopted, enabling the site of lymphorrhea to be identified and its approach to be planned, and embolization for lymphorrhea is now becoming feasible in an increasing number of patients. Even for patients in whom embolization is infeasible, identifying the site of leakage and providing the surgeon with this information is useful. Although this technique is still under development, interventional radiologists are now able to play a role in the treatment of lymphorrhea. Herein, we discuss lymphatic interventional radiology for lymphorrhea following gastrointestinal surgery.
The role of lymphatic interventional radiology for postoperative lymphorrhea
Shuji Kariya,Shintaro Yamamoto,Miyuki Nakatani,Yasuyuki Ono,Takuji Maruyama,Noboru Tanigawa 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.4
Lymphorrhea after gastrointestinal surgery may be treated conservatively or surgically, and treatment by lymphatic interventional radiology has also recently come into use. From pedal lymphangiography, intranodal lymphangiography was widely adopted, enabling the site of lymphorrhea to be identified and its approach to be planned, and embolization for lymphorrhea is now becoming feasible in an increasing number of patients. Even for patients in whom embolization is infeasible, identifying the site of leakage and providing the surgeon with this information is useful. Although this technique is still under development, interventional radiologists are now able to play a role in the treatment of lymphorrhea. Herein, we discuss lymphatic interventional radiology for lymphorrhea following gastrointestinal surgery.
Lee, Joon Hee,Nakama, Sueo,Oh, Dae Sik,Hoshino, Yuichi,Kariya, Yusei 대한척추외과학회 1998 대한척추외과학회지 Vol.5 No.2
Study Design : The same contents of questionnaire about the low back pain(LBP) were conducted among the Korean and the Japanese hospital workers. Objectives : To compare the prevalence of LBP and the correlates of occupation and care-seeking. Summary of Literature Review : Previous epidemiological researches about LBP were usually performed within a country, Korean researches were for the Korean population and Japanese for the Japanese. Material & Methods : The history, the cause, the frequency, the severity, and the method of treatment of LBP were compared between the Korean (N=336) and the Japanese (N=428) hospital workers Results : The prevalence of past LBP history were higher in Korean (80%) than in Japanese case (68%), but the percentage of care-seeking (Japan: 64% & Korea: 49%) and lost workdays (9% & 7%) were inverted. The prevalence was the highest in nurse occupation (73% & 89%), and most of these cases reported the cause of LBP as work-related (72% & 71%), which was much higher than the other occupations (34% & 39%). Among the care-seeking (Japan: N=186, Korea: N=131), the percentage of hospital visit was higher in Japanese (43%) than in Korean case (24%). The other methods of care included pharmacy, massage, finger-pressure therapy, acupuncture and moxa, and these were similarly preferred by two countries. Conclusion : Epidemiology of LBP was compared between Japanese and Korean hospital workers. Further study will be needed to compare the actual epidemiology of an LBP (232 words)
Kiguchi, Kazuo,Kariya, Shingo,Wantanabe, Keigo,Fukude, Toshio Institute of Control 2002 Transaction on control, automation and systems eng Vol.4 No.1
A decrease in the birthrate and aging are progressing in Japan and several countries. In that society, it is important that physically weak persons such as elderly persons are able to take care of themselves. We have been developing exoskeletal robots for human (especially for physically weak persons) motion support. In this study, the controller controls the angular position and impedance of the exoskeltal robot system using multiple fuzzy-neuro controllers based on biological signals that reflect the human subject's intention. Skin surface electromyogram (EMG) signals and the generated wrist force by the human subject during the elbow motion have been used as input information of the controller. Since the activation level of working muscles tends to vary in accordance with the flexion angle of elbow, multiple fuzzy-neuro controllers are applied in the proposed method. The multiple fuzzy-neuro controllers are moderately switched in accordance with the elbow flexion angle. Because of the adaptation ability of the fuzzy-neuro controllers, the exoskeletal robot is flexible enough to deal with biological signal such as EMG. The experimental results show the effectiveness of the proposed controller.
Diethyldithiocarbamate Suppresses an NF-κB Dependent Metastatic Pathway in Cholangiocarcinoma Cells
Srikoon, Pattaravadee,Kariya, Ryusho,Kudo, Eriko,Goto, Hiroki,Vaeteewoottacharn, Kulthida,Taura, Manabu,Wongkham, Sopit,Okada, Seiji Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7
Cholangiocarcinoma (CCA) is a tumor of biliary ducts, which has a high mortality rate and dismal prognosis. Constitutively activation of the transcription factor nuclear factor kappa-B (NF-${\kappa}B$) has been previously demonstrated in CCA. It is therefore a potential target for CCA treatment. Effects of diethyldithiocarbamate (DDTC) on NF-${\kappa}B$-dependent apoptosis induction in cancer have been reported; however, anti-metastasis has never been addressed. Therefore, here the focus was on DDTC effects on CCA migration and adhesiond. Anti-proliferation, anti-migration and anti-adhesion activities were determined in CCA cell lines, along with p65 protein levels and function. NF-${\kappa}B$ target gene expression was determined by quantitative RT-PCR. DDTC inhibited CCA cell proliferation. Suppression of migration and adhesion were observed prior to anti-CCA proliferation. These effects were related to decreased p65, reduction in NF-${\kappa}B$ DNA binding, and impaired activity. Moreover, suppression of ICAM-1 expression supported NF-${\kappa}B$-dependent anti-metastatic effects of DDTC. Taken together, DDTC suppression of CCA migration and adhesion through inhibition of NF-${\kappa}B$ signaling pathway is suggested from the current study. This might be a promising treatment choice against CCA metastasis.