http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Development and experimental study on cable-sliding modular expansion joints
Kang Gao,Wan C. Yuan,Xin Z. Dang 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.61 No.6
According to the characteristics of continuous beam bridges, the relative displacement is too large to collision or even girder falling under earthquakes. A device named Cable-sliding Modular Expansion Joints(CMEJs) that can control the relative displacement and avoid collision under different ground motions is proposed. Working principle and mechanical model is described. This paper design the CMEJs, establish the restoring force model, verify the force model of this device by the pseudo-static tests, and describe and analyze results of the tests, and then based on a triple continuous beam bridge that has different heights of piers, a 3D model with or without CMEJs were established under Conventional System (CS) and Seismic Isolation System (SIS). The results show that this device can control the relative displacement and avoid collisions. The combination of isolation technology and CMEJs can be more effective to achieve both functions, but it need to take measures to prevent girder falling due to the displacement between pier and beam under large earthquakes.
Rapid fabrication of NiFe(OH)x/Fe0.2Co-Se complexes for oxygen evolution reaction electrocatalysis
Kang Gao,Miao Xu,Chuankun Zhang,Haiming Huang,Dongming Cai,Minglei Cao,Jun Wu,Chengrui Wu,Yongjin Hu,Rui Tong 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.124 No.-
Exploiting the inexpensive and efficient oxygen evolution reaction (OER) electrocatalysts is crucial forimproving the efficiency of electrocatalytic water splitting (EWS), since the slow 4-electron OER processis a rate-limiting step in EWS. Herein, we prepared the NiFe(OH)x/Fe0.2Co-Se complexes on carbon paper(CP) via an easy two-step electrochemical deposition strategy. By varying the doping amount of Fe andthe deposition time of Fe0.2Co-Se, the OER property of NiFe(OH)x/Fe0.2Co-Se/CP was optimized to the best:only requiring low overpotentials of 243 and 277 mV at the current density of 20 and 100 mA/cm2 (j20and j100) and a small Tafel slope of 36.8 mV/dec, along with a terrific long-term durability in 1 M KOH. According to the experimental results, the rich exposed active sites, improved intrinsic site activityand enhanced electrical conductivity lead to the superior OER performance. Our work will provide someinspiration for designing other metal selenide/hydroxide heterostructures for other energy conversion orstorage applications.
시트르산처리와 열처리가 인삼 잎 중 진세노사이드의 함량 변화에 미치는 영향
김진혁, Gao Dan, 조종운, 강종성 충남대학교 약학대학 의약품개발연구소 2021 藥學論文集 Vol.36 No.-
The rare ginsenosides are seldom found in nature. However, they are recognized as showing higher biological activities than other ginsenosides. There are many reports about increasing the contents of rare ginsenosides in ginseng root using chemical, physical or biological methods. Some of the methods were very successful and contributed to increase the quality of the ginseng products. We tried to increase the rare ginsenosides in ginseng leaves with citric acid or heat treatment. In this way, the industrial value of ginseng leaves could be highly increased. The ginsenosides in untreated and treated ginseng leaves were identified and determined using high performance liquid chromatography with ultra- violet detection and mass spectrometry. The results showed that the contents of rare ginsenosides in- creased after heat treatment or citric acid treatment, however heat treatment was more effective. Furthermore, when the ginseng leaves were treated with 1 mol/L citric acid together with 3 hours of heat treatment, the contents of eight rare ginsenosides of Rg6, F2, F4, Rk3, Rg3(S), Rg3(R), Rk1, Rg5 were increased to 0.64%, 1.26%, 0.54%, 1.11%, 0.73%, 0.73%, 0.23%, 0.58% and 1.14%, respectively. This study suggested that the combined treatment of citric acid and heat treatment could be applied for the process of ginseng leaves with enhanced biological activities through increased contents of rare ginsenosides.
Choi, Hyunbong,Kang, Sang Ook,Ko, Jaejung,Gao, Guohua,Kang, Hong Seok,Kang, Moon-Sung,Nazeeruddin, Md. K.,Grä,tzel, Michael WILEY-VCH Verlag 2009 Angewandte Chemie Vol.48 No.32
<B>Graphic Abstract</B> <P>Dying to get inside: Charge recombination is retarded and dye aggregation is prevented in solar cells that contain the JK-2 dye encapsulated in a cyclodextrin (CD) cavity (see picture). The β-CD/JK-2 device with a polymer gel electrolyte gave an overall conversion efficiency of 7.40 %, which is the highest value reported to date for DSSCs based on the organic sensitizers, and showed excellent stability. <img src='wiley_img/14337851-2009-48-32-ANIE200902013-content.gif' alt='wiley_img/14337851-2009-48-32-ANIE200902013-content'> </P>
Adaptive Sliding Mode Based Disturbance Attenuation Tracking Control for Wheeled Mobile Robots
Kang Liu,Hongbo Gao,Haibo Ji,Zhengyuan Hao 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.5
This paper is devoted to investigating a composite controller for wheeled mobile robots in the presence of external disturbance and parametric uncertainty. Unlike the traditional backstepping technique existing the impractical velocity jumps, the proposed neural dynamic model has the ability to generate smooth continuous signals. Subsequently, a disturbance observer based adaptive sliding mode dynamic controller is introduced to estimate disturbances online, adjust control gain automatically and eliminate chattering phenomena completely. Under the developed control law, the ultimate boundedness of all signals is guaranteed and the tracking errors can be arbitrarily small in finite time. Simulation results are carried out to demonstrate the effectiveness of the proposed scheme.
Kang, Jeon-Hong,Ying, Gao,Cheng, Yuh-Chuan,Kim, Chang-Soo,Lee, Sang-Hwa,Yu, Kwang-Min The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.1
With approval from the Asia Pacific Metrology Program Working Group on Materials Metrology (APMP WGMM), an international comparison for sheet resistance standards for silicon wafers was firstly conducted among Korea Research Institute of Standards and Science (KRISS) in Korea, CMS/ITRI in Taiwan, and NIM in China, which are national metrology institutes (NMIs), from August 2011 to January 2012. The sheet resistance values of the standards are $10{\Omega}$, $100{\Omega}$, and $1000{\Omega}$; the measurement was conducted in sequence at KRISS, CMS/ITRI, NIM, and KRISS again using the four-point probe method with single and dual configuration techniques. The reference value for the measurement results of the three NMIs was obtained through averaging the values of the three results for each sheet resistance range. The differences between the reference value and the measured values is within 0.22% for $10{\Omega}$, 0.17% for $100{\Omega}$, and 0.12% for $1000{\Omega}$. Therefore, the international consistency for conducting sheet resistance measurements is confirmed within 0.22% through the APMP WGMM approved comparison.
Gao, M.Q.,Kim, B.G.,Kang, S.,Choi, Y.P.,Yoon, J.H.,Cho, N.H. Elsevier ; Elsevier Science Pub. Co 2013 Cancer letters Vol.336 No.1
We demonstrate here increased expression of ADAM17 protein in cancer-associated fibroblasts (CAFs) extracted from human breast carcinomas compared with donor-matched normal fibroblasts, and TGF-α secretion positively correlates with ADAM17 expression in these cells. In SK-BR-3 cells co-cultured with CAFs, CAF-secreted TGF-α promotes cell proliferation by activation of EGFR, Akt, and ERK, but it does not promote cell migration. Furthermore, anti-TGF-α neutralizing antibodies antagonize the CAF-dependent increase in proliferation and activation of EGFR, Akt and ERK. Thus, pharmacologic inhibition of ADAM17 and TGF-α may have therapeutic potential for the treatment of breast cancer when fibroblast-directed therapy is considered.
Kang, Xing,Chen, Rong,Zhang, Jie,Li, Gang,Dai, Peng-Gao,Chen, Chao,Wang, Hui-Juan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8
Background: Zinc transporters have been considered as essential regulators in many cancers; however, their mechanisms remain unknown, especially in gliomas. Isocitrate dehydrogenase 1(IDH1) mutation is crucial to glioma. This study aimed to investigate whether zinc transporters are correlated with glioma grade and IDH1 mutation status. Materials and Methods: IDH1 mutation status and mRNA expression of four zinc transporters (ZIP4, ZIP9, ZIP11, and ZnT9) were determined by subjecting a panel of 74 glioma tissue samples to quantitative real-time PCR and pyrosequencing. The correlations between the expression levels of these zinc transporter genes and the grade of glioma, as well as IDH1 mutation status, were investigated. Results: Among the four zinc transporter genes, high ZIP4 expression and low ZIP11 expression were significantly associated with higher grade (grades III and IV) tumors compared with lower grade (grades I and II) counterparts (p<0.0001). However, only ZIP11 exhibited weak correlation with IDH1 mutation status (p=0.045). Samples with mutations in IDH1 displayed higher ZIP11 expression than those without IDH1 mutations. Conclusions: This finding indicated that zinc transporters may interact with IDH1 mutation by direct modulation or action in some shared pathways or genes to promote the development of glioma. Zinc transporters may play an important role in glioma. ZIP4 and ZIP11 are promising molecular diagnostic markers and novel therapeutic targets. Nevertheless, the detailed biological function of zinc transporters and the mechanism of the potential interaction between ZIP11 and IDH1 mutation in gliomagenesis should be further investigated.
Gao, M-Q,Choi, Y-P,Kang, S,Youn, J H,Cho, N-H Macmillan Publishers Limited 2010 Oncogene Vol.29 No.18
Cancer stem cells (CSCs) have been identified in solid tumors and cancer cell lines. In this study, we isolated a series of cancer cell clones, which were heterogeneous in growth rate, cell cycle distribution and expression profile of genes and proteins, from ovarian tumor specimens of a patient and identified a sub-population enriched for ovarian CSCs defined by CD24 phenotype. Experiments in vitro demonstrated CD24<SUP>+</SUP> sub-population possessed stem cell-like characteristics of remaining quiescence and more chemoresistant compared with CD24<SUP>−</SUP> fraction, as well as a specific capacity for self-renewal and differentiation. In addition, injection of 5 × 10<SUP>3</SUP> CD24<SUP>+</SUP> cells was able to form tumor xenografts in nude mice, whereas equal number of CD24<SUP>−</SUP> cells remained nontumorigenic. We also found that CD24<SUP>+</SUP> cells expressed higher mRNA levels of some ‘stemness’ genes, including Nestin, β-catenin, Bmi-1, Oct4, Oct3/4, Notch1 and Notch4 which were involved in modulating many functions of stem cells, and lower E-cadherin mRNA level than CD24<SUP>−</SUP> cells. Altogether, these observations suggest human ovarian tumor cells are organized as a hierarchy and CD24 demarcates an ovarian cancer-initiating cell population. These findings will have important clinical applications for developing effective therapeutic strategies to treat ovarian cancer.