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      • 객체 관계형 데이타베이스 관리 시스템을 이용한 디지털 앨범의 설계 및 구현

        이준서,장염승,한기준 건국대학교 산업기술연구원 2000 건국기술연구논문지 Vol.25 No.-

        As the storage capacity of a computer system is rapidly increasing and the cost of computer hardware is decreasing continuously, users can easily manage multimedia data on the personal computer. Especially, various image view programs are widely used to manage image files at the present time. However, since most of these programs do not use a database management system(DBMS), it is very difficult for users to use them efficiently. In this paper, we designed and implemented a Digital Album by using an object-relational database management system, called PARODY(Persistent, Almost, Relational Object Database sYstem) that implements a persistent object database with a relatively simple interface to its C++ class library. Since PARODY is used as a data storage manager of the Digital Album, users can manage(i.e., insert, update, and delete) an image database and search for the required image data from the image database easily. In addition, we use OWL(Object Windows Library) of Borland C++ to implement the user interface of the Digital Album efficiently.

      • Health-related Quality of Life After Treatment for Malignant Bone Tumors: A Follow-up Study in China

        Sun, Yong-Jian,Hu, Yan-Jun,Jin, Dan,Li, Jian-Wei,Yu, Bin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        Aim: We conducted the present study to assess health-related quality of life (HRQoL) among bone cancer patients after surgical treatment in one large teaching hospitals in China, and assess the risk factors for improving the physical or mental HRQoL. Methods: 344 eligible adult patients who were admitted to the hospital with malignant bone tumors during the period of Jun. 2008 to Dec. 2011, and a reference group with 361 health cases was recruited in the same hospital during the same period. All 344 patients were followed up for one year. The HRQoL before treatment and after one year was evaluated with the Medical Outcome Short Form 36 (SF-36). Results: All 8 domains of HRQoL had the lowest scores greatly improved over the first year after discharge. However, the patients still had significantly lower scores in every domain than the reference group one year after discharge. Age and type of surgery were associated with HRQoL in the mental domain. Conclusion: The HRQoL of patients with malignant bone tumors greatly improved one year after the treatment. This study also highlighted the utility of HRQoL assessment for prognostic evaluation of patients after surgical treatment for bone cancer.

      • SCIESCOPUSKCI등재

        Production and Characterization of Ethanol- and Protease-Tolerant and Xylooligosaccharides-Producing Endoxylanase from Humicola sp Ly01

        ( Jun Pei Zhou ),( Qian Wu ),( Rui Zhang ),( Yu Ying Yang ),( Xiang Hua Tang ),( Jun Jun Li ),( Jun Mei Ding ),( Yan Yan Dong ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.6

        This paper reports the production and characterization of crude xylanase from the newly isolated Humicola sp. Ly01. The highest (41.8 U/ml) production of the crude xylanase was obtained under the optimized conditions (w/v): 0.5% wheat bran, 0.2% KH2PO4, and 0.5% peptone; initial pH 7.0; incubation time 72 h; 30℃; and 150 rpm. A considerable amount of the crude xylanase was induced using hulless barley bran or soybean meal as the carbon source, but a small amount of the enzyme was produced when supplementary urea was used as the nitrogen source to wheat bran. The crude xylanase showed apparent optimal cellulase-free xylanase activity at 60℃ and pH 6.0, more than 71.8% of the maximum xylanase activity in 3.0-30.0% (v/v) ethanol and more than 82.3% of the initial xylanase activity after incubation in 3.0-30.0% (v/v) ethanol at 30℃ for 2 h. The crude xylanase was moderately resistant to both acid and neutral protease digestion, and released 7.9 and 10.9 μmol/ml reducing sugar from xylan in the simulated gastric and intestinal fluids, respectively. The xylooligosaccharides were the main products of the hydrolysis of xylan by the crude xylanase. These properties suggested the potential of the crude enzyme for being applied in the animal feed industry, xylooligosaccharides production, and high-alcohol conditions such as ethanol production and brewing.

      • KCI등재

        Molecular and Biochemical Characterization of a Novel Intracellular Low-Temperature-Active Xylanase

        ( Jun Pei Zhou,),( Yan Yan Dong ),( Xiang Hua Tang ),( Jun Jun Li ),( Bo Xu ),( Qian Wu ),( Ya Jie Gao ),( Lu Pan ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.4

        A 990 bp full-length gene (xynAHJ2) encoding a 329- residue polypeptide (XynAHJ2) with a calculated mass of 38.4 kDa was cloned from Bacillus sp. HJ2 harbored in a saline soil. XynAHJ2 showed no signal peptide, distinct amino acid stretches of glycoside hydrolase (GH) family 10 intracellular endoxylanases, and the highest amino acid sequence identity of 65.3% with the identified GH 10 intracellular mesophilic endoxylanase iM-KRICT PX1-Ps from Paenibacillus sp. HPL-001 (ACJ06666). The recombinant enzyme (rXynAHJ2) was expressed in Escherichia coli and displayed the typical characteristics of low-temperatureactive enzyme (exhibiting optimum activity at 35 o C, 62% at 20 o C, and 38% at 10 o C; thermolability at ≥45 o C). Compared with the reported GH 10 low-temperature-active endoxylanases, which are all extracellular, rXynAHJ2 showed low amino acid sequence identities (<45%), low homology (different phylogenetic cluster), and difference of structure (decreased amount of total accessible surface area and exposed nonpolar accessible surface area). Compared with the reported GH 10 intracellular endoxylanases, which are all mesophilic and thermophilic, rXynAHJ2 has decreased numbers of arginine residues and salt bridges, and showed resistance to Ni 2+ , Ca 2+ , or EDTA at 10 mM final concentration. The above mechanism of structural adaptation for low-temperature activity of intracellular endoxylanase rXynAHJ2 is different from that of GH 10 extracellular low-temperature-active endoxylanases. This is the first report of the molecular and biochemical characterizations of a novel intracellular low-temperatureactive xylanase.

      • KCI등재

        Cloning, Heterologous Expression, and Characterization of Novel Protease- Resistant α-Galactosidase from New Sphingomonas Strain

        ( Jun Pei Zhou ),( Yan Yan Dong ),( Jun Jun Li ),( Rui Zhang ),( Xianghua Tang ),( Yuelin Mu ),( Bo Xu ),( Qian Wu ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.11

        The α-galactosidase-coding gene agaAJB13 was cloned from Sphingomonas sp. JB13 showing 16S rDNA (1,343 bp) identities of ≤97.2% with other identified Sphingomonas strains. agaAJB13 (2,217 bp; 64.9% GC content) encodes a 738-residue polypeptide (AgaAJB13) with a calculated mass of 82.3 kDa. AgaAJB13 showed the highest identity of 61.4% with the putative glycosyl hydrolase family 36 α-galactosidase from Granulicella mallensis MP5ACTX8 (EFI56085). AgaAJB13 also showed <37% identities with reported protease-resistant or Sphingomonas α-galactosidases. A sequence analysis revealed different catalytic motifs between reported Sphingomonas α-galactosidases (KXD and RXXXD) and AgaAJB13 (KWD and SDXXDXXXR). Recombinant AgaAJB13 (rAgaAJB13) was expressed in Escherichia coli BL21 (DE3). The purified rAgaAJB13 was characterized using p-nitrophenyl-α-D-galactopyranoside as the substrate and showed an apparent optimum at pH 5.0 and 60oC and strong resistance to trypsin and proteinase K digestion. Compared with reported proteaseresistant α-galactosidases showing thermolability at 50oC or 60oC and specific activities of <71 U/mg with or without protease treatments, rAgaAJB13 exhibited a better thermal stability (half-life of >60 min at 60oC) and higher specific activities (225.0-256.5 U/mg). These sequence and enzymatic properties suggest AgaAJB13 is the first identified and characterized Sphingomonas α-galactosidase, and shows novel protease resistance with a potential value for basic research and industrial applications.

      • SCOPUS

        Computing and Reducing Transient Error Propagation in Registers

        Jun Yan,Wei Zhang 한국정보과학회 2011 Journal of Computing Science and Engineering Vol.5 No.2

        Recent research indicates that transient errors will increasingly become a critical concern in microprocessor design. As embedded processors are widely used in reliability-critical or noisy environments, it is necessary to develop cost-effective fault-tolerant techniques to protect processors against transient errors. The register file is one of the critical components that can significantly affect microprocessor system reliability, since registers are typically accessed very frequently, and transient errors in registers can be easily propagated to functional units or the memory system, leading to silent data error (SDC) or system crash. This paper focuses on investigating the impact of register file soft errors on system reliability and developing cost-effective techniques to improve the register file immunity to soft errors. This paper proposes the register vulnerability factor (RVF) concept to characterize the probability that register transient errors can escape the register file and thus potentially affect system reliability. We propose an approach to compute the RVF based on register access patterns. In this paper, we also propose two compiler-directed techniques and a hybrid approach to improve register file reliability cost-effectively by lowering the RVF value. Our experiments indicate that on average, RVF can be reduced to 9.1% and 9.5% by the hyperblock-based instruction re-scheduling and the reliability-oriented register assignment respectively, which can potentially lower the reliability cost significantly, without sacrificing the register value integrity.

      • SCOPUS

        An Interference Matrix Based Approach to Bounding Worst-Case Inter-Thread Cache Interferences and WCET for Multi-Core Processors

        Jun Yan,Wei Zhang 한국정보과학회 2011 Journal of Computing Science and Engineering Vol.5 No.2

        Different cores typically share the last-level cache in a multi-core processor. Threads running on different cores may interfere with each other. Therefore, the multi-core worst-case execution time (WCET) analyzer must be able to safely and accurately estimate the worst-case inter-thread cache interference. This is not supported by current WCET analysis techniques that manly focus on single thread analysis. This paper presents a novel approach to analyze the worst-case cache interference and bounding the WCET for threads running on multi-core processors with shared L2 instruction caches. We propose to use an interference matrix to model inter-thread interference, on which basis we can calculate the worst-case inter-thread cache interference. Our experiments indicate that the proposed approach can give a worst-case bound less than 1%, as in benchmark fib-call, and an average 16.4% overestimate for threads running on a dual-core processor with shared-L2 cache. Our approach dramatically improves the accuracy of WCET overestimatation by on average 20.0% compared to work.

      • KCI등재

        The Effect of H2O2/Fe2+ Catalytic Oxidation System on the Morphology, Structure and Properties of Flake-Like Poly(2,3-dimethylaniline)

        Jun Yan,Li Ma,Mengyu Gan,Xiao Li,Zhitao Li,Jihai Tang,Ying Tu,Haifeng Hu 한국고분자학회 2014 Macromolecular Research Vol.22 No.8

        In this work, flake-like poly(2,3-dimethylaniline) (P(2,3-DMA)) with enhanced thermal stability andanticorrosive ability was synthesized by in situ polymerization using H2O2/Fe2+ catalytic oxidation system, comparingwith traditional oxidant ammonium persulfate (APS) synthetic method. The structure and morphology of thesamples were characterized Fourier transform infrared (FTIR) spectra, X-ray diffraction (XRD) and field-emissionscanning electron microscope (FESEM). The experimental results demonstrated that using H2O2/Fe2+ catalytic oxidationsystem was more inclined to form the two-dimensional P(2,3-DMA) flakes. The enhancement in thermostabilityand corrosion resistance was attributed to the formation of phenazine-like structures in the polymer chains,which could serve as templates to form the flake-like morphology. In addition, using H2O2/Fe2+ catalytic oxidationsystem is more environmental friendly than the APS method that can avoid ammonium pollution on aquatic life aswell as waters.

      • KCI등재

        Improved Longitudinal Displacement Profile and Initial Support for Tunnel Excavation

        Yan-Jun Zhang,Kai Su,Zhong-Dong Qian,He-Gao Wu 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.6

        The ground support system has a significant impact on tunnel safety while the installation time of initial support is commonly designed by empirical method. The three dimensional numerical model, based on the engineering practice, is analyzed by FLAC3D. In this paper, an improved LDP (longitudinal displacement profile) equation is proposed, which is more accurate in describing the convergence of tunnel before excavation face reaching. Then, a methodology is presented to determine the installation location of initial support in a more efficient and effective way. By simulating the process of excavation load releasing, the appropriate time for installing initial support is when the evolution of surrounding rock displacement has a tendency to increase rapidly, namely that the stability of rock mass arrives at the critical state. The mathematical relationship between the convergence of tunnel and the relative location to tunnel face can be established by fitting monitoring data with the improved LDP equation. Substituting the critical tunnel convergence into the LDP relationship, the corresponding installation location of initial support will be calculated. Meanwhile, several schemes with diverse geological conditions are carried out to validate the improved LDP and the methodology.

      • KCI등재

        Output Feedback Stabilization for an ODE Coupled with a Wave Equation with Variable Coefficients

        Yan Xing Zhao,Jun Jun Liu,Yan Na Jia 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.2

        In this paper, we are concerned with the output feedback problem for coupled ODE-wave systems subject to spatially-varying coefficients. An original transformation is designed to turn the wave equation into an equation of the same type with constant coefficient and low order term. Taking advantage of the backstepping method, a state observer is constructed by non-collocated boundary displacement and velocity measurement. Output feedback on the based of the observer output feedback is then constructed, which makes use of the backstepping method to make the system exponentially stable. Finally, we demonstrate the well-posed and the exponential stability of the closed-loop system.

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