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Jeongsoo Kim 건국대학교 모빌리티인문학 연구원, 건국대학교 아시아·디아스포라 연구소 2024 International Journal of Diaspora&Cultural Critici Vol.14 No.1
The meaning of happiness in human life depends on what each individual thinks of as happiness and what one pursues due to differences in personalities and values. An important value and ideology of modern constitution is the guarantee of human rights to ensure that all human beings can live the life they want. Therefore, the meaning of the right to pursue happiness can be seen as very important not only at the time of the modern human rights declaration, but also in modern society, where technological breakthroughs and artificial intelligence are emerging at ever-higher rates. The role of law is also very important in an intelligent information society, and it is also necessary to find out what fundamental rights the state should protect more actively through the interpretation and guidelines of the Constitution and include the necessary legislative direction or outline in the constitutional amendment. It is crucial to prepare for risks caused by the emergence of new technologies and the development of an intelligent information society, to protect the fundamental rights and safety of the people, and to review constitutional countermeasures. If successful, it may be possible to establish a normative framework for pursuing safe and sustainable development and human happiness.
Marginal zone B-cell lymphoma associated with MALT lymphoma of parotid gland
( Jeongsoo Kim ),( Seulki Lee ),( Haryeong Ryu ),( Chulhyun Yoon ),( Jinok Baek ),( Jongrok Lee ),( Jooyoung Roh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Cutaneous Marginal zone B-cell lymphoma (CMZL) is known as extranodal mucosa associated lymphoid tissue (MALT) lymphoma arising at skin accounting for 11% of various extranodal organs. CMZL has indolent behavior and excellent prognosis but recurrence is common. Typically, it manifests as single or multiple, clustered erythematous or violaceous papules, plaques, or nodules. The lesions occur most commonly on the trunk and upper extremities. Histologically, CMZL is composed of polymorphous infiltrate that includes centrocyte-like, monocytoid, and lymphoplasmacytoid lymphocytes and plasma cells. CMZL can be managed with either conservative skin-directed strategies, such as surgical excision and topical steroid, or radiotherapy. A 78-year-old male patient presented with round elevated soft plaque on his back for 2 years. He was diagnosed as MZL of the parotid gland, and underwent surgical excision, radiotherapy and chemotherapy (CHOP) 9 years ago. Histopathologic of the skin showed nodular infiltrate of lymphocytes forming dense, irregulary shaped aggregates in the reticular dermis to subcutaneous tissue. Immunohistochemistry findings revealed positive for CD20, Bcl-2, CD5 and negative for Cyclin D1. There was no evidence of recurrence of previous lymphoma and no sign of metastasis with PET-CT. He was treated with radiotherapy. We report a rare case of CMZL that was formed from patient who had been diagnosed as MZL of the parotid gland.
Squamous cell carcinoma in situ successfully treated with ingenol mebutate 0.015%
( Jeongsoo Kim ),( Seulki Lee ),( Haryeong Ryu ),( Chulhyun Yoon ),( Jinok Baek ),( Jongrok Lee ),( Jooyoung Roh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Cutaneous squamous cell carcinoma(cSCC) is the second most common skin cancer in the US. Many cSCCs are small low-risk cancers and are usually effectively managed using minor surgical procedures. However, alternative treatment options are sometimes required, for example, when a patient refuses a surgical procedure, surgical treatment is contraindicated due to possible morbidity or cosmetic deformity and patient condition is compromised by age or the presence of comorbidities. Topical therapy is usually preferred by these patients. Ingenol mebutate has a dual mechanism of action involving the rapid induction of cellular death and cellular cytotoxicity triggered by neutrophils and antibodies. And it has limited local side effect and is applied easily. A 92-year-old Asian woman presented at our dermatology clinic with an erythematous, rough, oozing, crusted lesion of the scalp. In 2011, she has been diagnosed with actinic keratosis of the scalp but dropped out. At this presentation the lesion had became more severe and was biopsied under the suspicion of SCC. We decided to treat the lesion with ingenol mebutate gel (0.015%) daily, and administered two cycles of 3 consecutive days per month for two months. One month after the second cycle the lesion had almost resolved and this was confirmed by biopsy. We report a rare case of cSCC in situ that was treated by ingenol mebutate that is considered an alternative to surgery.
Development of Gustatory Stimulation System for the Imaging of Taste Information Processing
( Jeongsoo Han ),( Minjee Kwon ),( Yongho Kwak ),( Bong Soo Kim ),( Jin Woo Chang ),( Motomasa Tanioka ),( Minjee Kim ),( Bae Hwan Lee ) 한국감성과학회 2015 추계학술대회 Vol.2015 No.-
Research for taste function is necessary as there are increasing interests in food ingestion and appetite. However, imaging studies for taste have been sparse because there are few taste stimulation devices. As neuroimaging technique advances, researches of brain function take advantage of brain imaging system. Here, we developed the taste stimulation system using non-conductive materials for brain imaging tool which is sensitive to magnetic artifact. There are three parts of this stimulator: Air flow control box, heat insulating tastant reservoir including supply tubing and mouthpiece for spraying tastant and suctioning waste solution. Firstly, air flow control box can supply and stop the compressed air in accurate timing, cycle and duration which can be adjusted. This controller can be located in outside of the imaging room, so that researcher can manipulate easily. Secondly, we installed the insulating tastant reservoir and tastant supply pipe to maintain the tastant temperature to body temperature. It is important part to obtain only taste signals. Lastly, the mouthpiece provides comfortable wearing sensation. Moreover, the mouthpiece can apply tastant to the specific tongue area using Y-shaped tubing and provide suction of tastant and washing solution. Therefore, the imaging study of taste information processing can be achieved successfully by using this gustatory stimulation system. This research was supported by the Basic Science Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (No. 2015021989).