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- 저자 : Jeong-An Jo (검색결과 243 건)
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Jeong Woo Shin,Sungje Lee,Dohyun Go,Byung Chan Yang,Taeyoung Kim,Sung Eun Jo,Pei-Chen Su,Jihwan An 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.3
Designing highly active and thermally stable electrodes is crucial for realizing low-temperature solid oxide fuel cells (LT-SOFCs) with excellent performance. In this study, we fabricated an yttria-doped ceria (YDC) shell layer by atomic layer deposition (ALD) over a Pt cathode by controlling the doping concentration of yttria in YDC film. The exchange current density was enhanced by a factor of five when the ALD YDC shell layer was deposited onto the cathode surface compared to the bare Pt cathode, resulting in an 80% decrease in the activation resistance of the 19 mol%-doped ALD YDC-overcoated Pt cathode compared to that of the bare Pt cathode. Furthermore, the thermal stability was enhanced in low-to-medium-doped (7–19 mol%) ALD YDC-coated Pt cathodes, whereas the highly doped (31 mol%) cathode showed a relatively marginal improvement in stability.
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Jeong Yeon An,Hae In Yong,So Yeon Kim,Han Bit Yoo,Yoo Yong Kim,Cheorun Jo 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.2
The objective of this study was to evaluate the effect of different levels of palm kernel meal (PKM), an alternative to corn, on the quality of pork. A total of 72 crossbred pigs ([Yorkshire × Landrace] × Duroc) were assigned into four dietary treatments (PKM level of 0, 4, 8, or 12%). After 12 wk, one pig of median weight in each pen was selected and slaughtered to analyze meat quality. The color, free radical scavenging activity, lipid oxidation, texture, composition of fatty acids, and sensory qualities of pork loin were evaluated post slaughter. When the levels of PKM in the diet increased, the L*-value of pork loin decreased, whereas a*-value and total saturated fatty acids increased. 2-Thiobarbituric acid reactive substance (TBARS) values of pork loin were lower in groups treated with 8 and 12% PKM than in the control group at day 0; this difference, however, was not observed at day 3 and 7. The results of texture analysis showed that increasing the PKM ratio decreased hardness, chewiness, and springiness at day 7. The sensory test, however, indicated no differences between the control and treated groups. These findings show that finisher pigs could tolerate PKM as a replacement for corn; PKM did not negatively affect the quality of pork, indicating that it can be utilized as feed.
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Jeong Woonhyeok,Hong Jamin,Jung Minho,Jang Mijin,An Sanghyun,Jo Taehee,Kwon Sunyoung,손대구 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.1
Background Chitosan (CS) is a well-known antimicrobial dressing material. Moreover, widely used amniotic membranes contain growth factors beneficial for wound healing. Herein, we created a novel amnion-conjugated CS-alginate membrane dressing and tested its wound healing potency in a diabetic swine model.Methods The bovine amniotic powder growth factor contents were evaluated by protein assay, and the powder's wound healing effects were assessed in vitro by HaCaT cell scratch closure. In vivo, two minipigs developed streptozotocin-induced diabetes. Serial serum glucose measurements and intravenous glucose tolerance tests were performed to confirm their diabetic status. Twelve square-shaped wounds created on each pig's back were randomly divided into control (n = 4), CS (n = 4), and amnion-CS (AC; n = 4) groups and treated accordingly with different dressings. Wound healing in each group was assessed by measuring wound contraction over time, capturing wound perfusion with indocyanine green (ICG) angiography, and histologically analyzing inflammatory markers.Results Amniotic powder elution promoted HaCaT cell migration in the scratch wound model, suggesting its beneficial in vitro wound healing effects. In vivo, the CS and AC groups showed earlier wound contraction initiation and reepithelialization and earlier wound perfusion improvement by ICG angiography than the control group. Additionally, the wound size of the AC group at week 3 was significantly smaller than those in the control group. There was no significant difference in the numbers of acute and chronic inflammatory cells between the groups.Conclusion The amnion-conjugated CS-alginate membrane, as well as CS dressing alone, could be a favorable dressing option for diabetic wounds.
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Jo-Eun YU,Mi-Young SON,Yeo-Myung YOON,Eun-Seo AN,Si-Eun YU,Jeong-Eun YOO,이도영 한국웰빙융합학회 2023 웰빙융합연구 Vol.6 No.4
Purpose: The purpose of this study is that the college age is an important transition period from youth to adulthood. Nursing students are unfamiliar with their field of study and need to adapt to a large amount of academic and practical training, so that they can have a better college life. An attempt was made to determine the effect of exam anxiety, academic stress, and alcohol dependence on the academic achievement of nursing students. Research design, data, and methodology: The subjects of the study were 130 students from all grades who agreed to participate in the study after expressing convenience among students attending the Department of Nursing at a university in Gyeongnam. The data collection period was from August 15 to September 15, 2023. It was about a month. The data investigation was conducted through a self-report survey. Results: Results showed that significant variables included exam anxiety, academic stress, alcohol dependency, parent relationships, peer relationships, and major satisfaction, explaining a total variance of 31.9%. Among these, the most influential factor was academic stress (β=-.352). Conclusions: This study identify factors influencing the academic achievement of nursing college students and hopes to contribute to formulating strategies for their growth and competence development.
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Jeong Woonhyeok,Hong Jamin,Jung Minho,Jang Mijin,An Sanghyun,Jo Taehee,Kwon Sunyoung,손대구 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.2
Background Chitosan (CS) is a well-known antimicrobial dressing material. Moreover, widely used amniotic membranes contain growth factors beneficial for wound healing. Herein, we created a novel amnion-conjugated CS-alginate membrane dressing and tested its wound healing potency in a diabetic swine model.Methods The bovine amniotic powder growth factor contents were evaluated by protein assay, and the powder's wound healing effects were assessed in vitro by HaCaT cell scratch closure. In vivo, two minipigs developed streptozotocin-induced diabetes. Serial serum glucose measurements and intravenous glucose tolerance tests were performed to confirm their diabetic status. Twelve square-shaped wounds created on each pig's back were randomly divided into control (n = 4), CS (n = 4), and amnion-CS (AC; n = 4) groups and treated accordingly with different dressings. Wound healing in each group was assessed by measuring wound contraction over time, capturing wound perfusion with indocyanine green (ICG) angiography, and histologically analyzing inflammatory markers.Results Amniotic powder elution promoted HaCaT cell migration in the scratch wound model, suggesting its beneficial in vitro wound healing effects. In vivo, the CS and AC groups showed earlier wound contraction initiation and reepithelialization and earlier wound perfusion improvement by ICG angiography than the control group. Additionally, the wound size of the AC group at week 3 was significantly smaller than those in the control group. There was no significant difference in the numbers of acute and chronic inflammatory cells between the groups.Conclusion The amnion-conjugated CS-alginate membrane, as well as CS dressing alone, could be a favorable dressing option for diabetic wounds.
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안영근 ( An Yeong Geun ),박주형 ( Park Ju Hyeong ),정명호 ( Jeong Myeong Ho ),조정관 ( Jo Jeong Gwan ),박종춘 ( Park Jong Chun ),강정재 ( Kang Jeong Jae ) 대한내과학회 1993 대한내과학회지 Vol.44 No.3
연구배경 : 확장형 심근증은 정확한 원인이 밝혀지지 않은 심비대를 특징으로 하며 종국에 가서는 좌심실기능부전에 의한 증상을 수반하는 질환이다. 최근에 이 질환에 대한 관심이 많이 높아졌으나 원인, 역학, 병인, 병리, 임상경과, 예후등은 아직도 명확하지 않은 바가 많다. 방법 : 본 연구는 1980년 1월부터 1991년 7월 사이에 전남대학교 병원순환기 내과에서 관찰된 학장형 심근증환자들을 대상으로 한국인 확장형 심근중 환자의 임상양상 및 예후에 영향을 미치는 인자들에 대하여 관찰하였다. 결과 : 1) 평균 연령은 56.3±13.6세였고 남자가 110명, 여자가 61명 이었다(남녀비=1.8 : 1). 2) NYHA 기능분류는 평균 3.2±0.7 이었고 내원당시 증상을 나타낸 기간은 1개월 이내가 38.6%, 6개월 이내가 61.4%, 그리고 1년 이상이 26.9% 이었다. 3) 내원당시 주요증상은 노작성 호흡곤란(86.5%), 기좌호읍(28.7%), 기침(21.1%), 심계항진(18.7%), 흉부불쾌감(17.0%), 그리고 발작성 야간 호흡곤란(9.4%)등이었다. 4) 내원당시 흔히 발견된 비정상 이학적 검사 소견은 촉지할수 있는 간 비대, 폐포음, 하지부종, 분마음, 경정맥압 상승, 심첨부 수축기 심잡음 등이었다. 5) 휴식시 심전도에서 관찰된 부정맥은 심방세동(28.7%), 심실성 기외수축(17.0%), 완전좌각차단(13.5%), 심실상성 빈맥(2.9%), 심실성 빈맥(1.2%) 등이었다. 6) 내원당시 M형 심초음파검사 소견상 좌심실의 내경은 이완기 6.9±0.9㎝, 수축기5.9±1.1㎝ 이었고 좌심방의 내경은 4.8±0.8㎝, 좌심실구혈율은 36.7±12.8, 승모판막 E점과 심실중격간 분리거리는 24.6±8.8mm, 좌심방의 총구혈율은 31.4±12.7%, 초기 구혈율은 19.8±10.1%이었다. 7) 이차성 심근증에서 동반질환이나 심근에 영향을 줄 수 있는 인자로는 고혈압, 중등도 이상의 음주력, 당뇨병, 만성폐쇄성 폐질환, 만성 간질환, 급성 간염, 임신 및 출산, 갑상선 기능 항진증, 전신성 홍반성 낭창 등 이었다. 8) 평균 추적 관찰기간은 10.8±9.4개월 이었고 6개월 이상 추적 관찰이 가능하였던 예는 원발성 심근증의 50명(51.5%), 이차성 심근중 38명(62.3%) 이었고 약 20%에서 3년이상 관찰할 수 있었다. 대부분의 환자들은 digoxin, 이뇨제, 혈관확장제, 칼슘이온 길항제 그리고 β수용체 차단제 중에서 두가지 이상의 약제를 투여 받았으며 추적 관찰기간동안 약물 투여중 증상의 호전은 63.3%에서 관찰되었으며 19.6%에서는 큰 변화가 없었으며 4.4%에서는 악화되었다. 9) 사망이 확인된 20명의 사망원인은 급사가 12명이었고 울혈성 심부전 5명, 뇌 혈관장애 2명, 혈관촬영 후 급성신부전 1명 이었다. 10) 원발성군 (A)과 이차성군(B)간의 임상상이나 검사 소견 및 예후에 통계적으로 유의한 차이는 없었다. 11) 사망이 확인된 20명과 증상이 악화된 9명을 대상으로 다변량회귀분석법으로 검증한 바 예후에 영향을 주는 주요인자는 심전도상의 심실내 전도장애, 양측 심방비대, NYHA 기능분류(Ⅲ이상) 그리고 경정맥압 상승이었다. 그러나 증상발현부터의 기간, 동반된 질환, 심초음파상 좌심실 구혈율, 승모판막 E점과 심실중격간 분리거리, digoxin, 이뇨제, 혈관 확장제등의 투여한 약물의 종류에 대해서는 통계적으로 의미있는 관계를 찾지 못하였다. 결론 : 본 연구에서 확장형 심근증의 임상양태는 서양의 보고와 큰 차이가 없었으며 향후 보다 많은 확장형 심근증 환자를 대상으로 치료전에 심장의 기능을 정확하게 평가하고 강심제, 이뇨제, β수용체 차단제, 칼슘이온 길항제, 혈관 확장제등의 약제를 투여하여, 임상증상 및 심장기능의 변화를 평가함으로써 확장형 심근증의 장기적 예후에 영향을 줄 수 있는 인자에 대한 전향적인 연구가 필요하리라 생각된다. Background : Dilated cardiomyopathy is a progressive disease of uncertain origin and the prediction of the clinical course in an individual patient remained to be defined. Method : In order to understand the clinical manifestation, laboratory findings, clinical courses and prognostic factors of Korean patents with dilated cardiomyopathy, the medical recordings of 171 patients with dilated cardiomyopathy (103 primary, 68 secondary) were reviewed. Results : 1) Studied subjects were 110 male and 61 female patients and aged of 56.3±13.6 years. 2) NYHA functional class was 3.2±0.7 and duration of symptoms were shorter than one month in 38.6%, shorter than 6 month 61.4%, and longer than one year in 26.9%. 3) Most common complaints were exertional dyspnea (86.5%), orthopnea (28.7%), cough (21.1%), palpitation (18.7%), chest discomfort (17.1%), and paroxysmal nocturnal dyspnea (9.4%). 4) Physical findings were palpable liver, rales in lungs, pitting edema, gallop rhythm, increased jugular venous pressure (JVP), apical systolic murmur, etc. 5) Dysarrhythmias including atrial fibrillation (28.7%), premature ventricular contraction (17.0%), complete left bundle branch block (13.5%), paroxysmal supraventricular tachycardia (2.9%), and ventricular tachycardia (1.2%) were observed. Abnormal EKG findigs other than dysarrhythmias were left ventricular hypertrophy, left atrial hypertrophy, myocardial is-chemia, non specific ST-T change, and right atrial hypertrophy, etc. 6) The M-mode echocardiogram at the first examination revealed that the left ventricular end-diastolic and end-systolic dimensions were 6.9±0.9㎝, 5.9±1.1㎝, ejection fraction 36.7±12.8%, lefr atrial dimension 4.8±0.8㎝, mitral E point septal separation (EPSS) 25±9mm, total and rapid emptying fraction of left atrium 31.4±12.7%, 19.8±10.1%. 7) Associated diseases or factors which may contribute to damage myocardium in secondary form of dilated cardiomyopathy patients were hypertension, heavy alcohol abuse, diabetes mellitus, chronic obstructive pulmonary disease, chronic liver disease, acute viral hepatitis, peripartum, hyperthyroidism, and systemic lupus erythematosus, etc. 8) Most patients were treated by two or more combined drug regimens and clinical responses to the medical treatment during the follow-up period (mean 1.8±9.4 months) were improved in 63.3%, unchanged in 19.6%, deteriorated in 4.4%, and dead in 12.7%. 9) Caused of death were sudden in 12 patients, congestive heart failure 5, cerebrovascular accident 2, and acute renal failure after angiography one. There were no significant differences between primary and secondary form of dilated cardiomyopathy patients groups, statistically. 10) Multiple logistic regression analysis revealed that the important prognostic factors were intraventricular conduction disturbance, atrial hypertrophy in EKG, NYHA functional class more than Ⅲ, and elevated JVP. Conclusion : Clinical manifestations of dilated cardiomyopathy are not much different from those reported in western countries. The majority of the patients can be benefited with currently available medical treatment at least in a short term period. A prospective studies are necessary to identify the risk factors and long-term natural history in conjunction with periordic follow-up endomyocardial biopsies after treatment with various suggested regimens to elucidate their long-term benefit.
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