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      • KCI등재

        The Role of Multiple Mediating Effects of SNS Channel between Perceived Quality and Revisit Intention in Coffee Concept Shops

        Lee,Jee Eun,Lee,Sang Suk 한국상품학회 2021 商品學硏究 Vol.39 No.5

        The purpose of this study is to examine the relationship between the perceived quality and revisit intention of the use of SNS, and then verifies the mediating role of the SNS channel between them. To achieve the purpose of this study, a total of 350 questionnaires were distributed at various coffee concept shops in the Korean metropolitan area (Seoul / Gyeonggi), including global / domestic brands. After removing the response with the missing information, the sample was 320 (91.4%). A structural equation model using AMOS 20.0 tested the hypotheses. Hypotheses are tested and confirmed by analyzing Korean coffee concept shops and the results have shown that information sharing and interaction of SNS play an important role in understanding perceived quality and revisit intention. Moreover, this study empirically verifies that when customers recognize the quality of products, including service and experience quality, they use SNS channels to visit the coffee shop again. The result of the study supported that information sharing and interactivity of SNS played critical roles in understanding perceived qualities and revisit intention. We empirically provide evidence that product quality of perceived qualities has direct positive in fluence on SNS channel and revisit intention. In addition, information sharing and interactivity of SNS channel has indirect significant impacts on intent to revisit. The result of research has shown that product quality had crucial impact on SNSs channel than service or experience quality. The study also shows that increasing the quality level of a product has a positive relationship with social media channels, which in turn can have a positive effect on information sharing and interactions. This study empirically examines that when customers perceive a product quality including service and experience quality, it induces them to use SNS channel, which eventually make them to revisit the store.

      • 생약제제인 이공산(異功散)의 Cisplatin 유도 신장독성 보호 및 항산화 효과

        Lee, Kyung-Tae,Ahn, Kyoo-Seok,Chang, Sung-Goo,Oh, Soo-Myung,Jung, Jee-Chang 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Kyung-Tae Lee, Kyoo-Seok Ahn¹, Sung-Goo Chang², Soo-Myung Oh²and Jee-Chang Jung²¹College of Pharmacy, ²Oriental Medicine and ³College of Medicine, and East-West Medical Reserch Institute, Kyung Hee University, Seoul, Korea. Preventive and Antioxidative Effects of Crude Drug Preparation(E-kong-san) on Cisplatin Induced Nephrotoxicity. Proceedings of International Symposium on East-West Medicine, Seoul. 201-211, 1999. -Nephroprotective effects of a crude drug-prearation (E-kong-san) were determined from cisplatin on rabbit kidney proximal tubule and human renal cortical cells by MTT assays and sustained glucose consumption on ciplatin-induced human renal cortical tissue. Levels of creatinine and blood ure nitrogen(BUN) in serum after administration of cisplatin(0.75mg/kg,i.p.) to E-kong-san(0.75g/kg/day,p.o.)-pretreated rats were markedly lower compared to those of cisplatin-treated rats. Moreover, the administration of E-kong-san significantly inhibited the loss of body weight of cisplatin injected rts. These findings suggest that E-kong-san on the cisplatin induced nephrotoxicity led us to investigate whether the effect of this water extract was a result of anti-oxidation. E-kong-san showed strong free radical scavenger activities on 1,1-dipheny1-2picrylhydrazil(DPPH) radical and xanthine/xanthine oxidase(XOD) generated superoxide anion radical(O2-). We further studied the effects of E-kong-san on lipid peroxidation in rat liver microsomes induced by enzymatic and nonenzymatic methods. E-kong-san exhibited significant inhibition on both ascorbic acid/Fe2+and ADP/NADPH/Fe3+ induced lipid peroxidation in rat liver microsomes. Based on these results, we suggest that-E-kong-san attenuate the cisplatin induced cytotoxicity and its mechanism can be eplained by antioxidant.

      • P211 : Red blood cell distribution width is increased in patients with psoriasis vulgaris: a retrospective study on 261 patients

        ( Dae Suk Kim ),( Dongyun Shin ),( Minseok Lee ),( Hyunjoong Jee ),( Tae Gyun Kim ),( Sung Hee Kim ),( Do Young Kim ),( Soo Min Kim ),( Min Geol Lee1 ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

        Background: Circulating inflammatory cytokines and markers are increased in patients with psoriasis. Recent studies have shown that a higher red blood cell distribution width (RDW) is associated with disease activity in various disorders. Objectives: Our objective was to investigate whether RDW is increased in psoriasis patients, and to evaluate its association with disease severity. Methods: We conducted a retrospective study of psoriasis patients seen in single hospital in Korea. Demographic data, hematologic parameters and disease severity were collected. Results: A total of 261 psoriasis patients and 102 healthy controls were included in our study. The RDW value was significantly increased in psoriasis patients compared to healthy control (p=0.037). Compared to mild psoriasispatients (PASI<7), moderate to severe patients (PASI≥7) showed significantly higher RDW values (p=0.044). RDW did not show significant correlation with PASI (p=0.358). When patients were divided into two groups according to their RDW value (<14.6% and ≥14.6%), the mean value of PASI was not significantly different (p=0.219). Conclusion: Patients with psoriasis showed increased RDW values compared to healthy controls. It was also higher in moderate and severe disease group than mild group. RDW values were increased in psoriasis patients and it is possible that RDW value reflects the inflammatory status of psoriasis, but this needs to be evaluated in near future.

      • Primary cutaneous diffuse large B-cell lymphoma, leg type, presenting as drug eruption-like morbiliform eruption

        ( Sang Hyung Lee ),( Hyun Ji Kang ),( Woo Jin Lee ),( Chong Hyun Won ),( Sung Eun Chang ),( Mi Woo Lee ),( Jee Ho Choi ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

        Primary cutaneous diffuse large B-cell lymphoma, leg type is a well-defined entity of cutaneous B-cell lymphoma affecting predominantly elderly patients, mostly women. The typical clinical presentation is characterized by solitary or multiple, rapidly growing plaques or tumors on 1 leg. We report this lymphoma in a 61-year-old man. He presented with a 2-year history of erythematous drug eruption-like morbiliform eruption on his chest, flank, back, and extremities. Complete staging investigations revealed no extracutaneous involvement. Histological examination of the morbiliform eruption showed perivascular infiltration composed predominantly of small lymphocytes admixed with several large blasts. They stained positively for CD20, CD79, and bcl-2 and revealed the negativity for bcl-6, CD4, and CD8. Our case suggest that drug eruption-like morbiliform eruption is a novel clinical feature of primary cutaneous diffuse large B-cell lymphoma

      • KCI등재

        Early versus late bedside endoscopy for gastroin-testinal bleeding in critically ill patients

        ( Jee Hyun Kim ),( Ji Hye Kim ),( Jaeyoung Chun ),( Changhyun Lee ),( Jong Pil Im ),( Joo Sung Kim ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.2

        Background/Aims: Gastrointestinal (GI) bleeding is a life-threatening complication in critically ill patients. The aim of this study was to determine the efficacy of bedside endoscopy in an intensive care unit (ICU) setting, and to compare the outcomes of early endoscopy (within 24 hours of detecting GI bleeding) with late endoscopy (after 24 hours). Methods: We retrospectively reviewed the medical records of patients who underwent bedside endoscopy for nonvariceal upper GI bleeding and lower GI bleeding that occurred after ICU admission at Seoul National University Hospital from January 2010 to May 2015. Results: Two hundred and fifty-three patients underwent bedside esophagogastroduodenoscopy (EGD) for upper GI bleeding (early, 187; late, 66) and 69 underwent bedside colonoscopy (CS) for lower GI bleeding (early, 36; late, 33). Common endoscopic findings were peptic ulcer, and acute gastric mucosal lesion in the EGD group, as well as ischemic colitis and acute hemorrhagic rectal ulcers in the CS group. Early EGD significantly increased the rate of finding the bleeding focus (82% vs. 73%, p = 0.003) and endoscopic hemostasis (32% vs. 12%, p = 0.002) compared with late EGD. However, early CS significantly decreased the rate of identifying the bleeding focus (58% vs. 82%, p = 0.008) and hemostasis (19% vs. 49%, p = 0.011) compared with late CS due to its higher rate of poor bowel preparation and blood interference (38.9% vs. 6.1%, p = 0.035). Conclusions: Early EGD may be effective for diagnosis and hemostatic treatment in ICU patients with GI bleeding. However, early CS should be carefully performed after adequate bowel preparation.

      • KCI등재

        Incidence of Dental Discoloration After Tetracycline Exposure in Korean Children: A Nationwide Population-Based Study

        Lee Ji Young,Kim Eun Hwa,Lee Myeongjee,Shin Jehee,Lim Sung Min,Baek Jee Yeon,Kim MinYoung,Ahn Jong Gyun,Kang Chung-Min,Jung Inkyung,Kang Ji-Man 대한소아감염학회 2024 Pediatric Infection and Vaccine Vol.31 No.1

        Purpose: Tetracycline is not recommended for children under 12 by guideline due to the risk of tooth discoloration. We aimed to assess the incidence of dental discoloration in Korean children prescribed tetracyclines and investigate whether its risk was greater in tetracyclineexposed children than in the general population. Methods: This population-based cohort study using the Health Insurance Review and Assessment service database included children aged 0–12 years exposed to tetracyclines for at least 1 day between January 2008 and December 2020. The primary outcome was the incidence rate of dental discoloration ≥6 months after prescription, and the standardized incidence ratio (SIR) was evaluated as secondary outcome. Results: 56,990 children were included—1,735 and 55,255 aged <8 and 8–12 years, respectively. 61% children were prescribed tetracycline for <14 days with mostly secondgeneration tetracyclines, doxycycline (61%) and minocycline (35%). The 5- and 10-year cumulative incidence rates of dental discoloration were 4.1% (95% confidence interval [CI], 3.0–5.7%) and 5.7% (95% CI, 4.1% to 7.8%), respectively, in the 0–7 years age group and 0.8% (95% CI, 0.7% to 0.9%) and 1.3 (95% CI, 1.1% to 1.4%), respectively, in the 8–12 years age group. Tetracycline exposure did not increase such risk compared to that in the general population (SIR, 1.08; 95% CI, 0.69 to 1.60). Conclusions: The incidence of dental discoloration was lower than previously suggested. Relieving the age restriction for prescribing tetracyclines may be considered.

      • KCI등재후보

        Electronic Imeging System with Silver Halide Photography Emulation

        (Jee Hong Kim),(Sang Nam Lee) 한국화상학회 2000 한국화상학회지 Vol.6 No.2

        본 논문은 은염사진의 노광, 현삼, 인화 공정과 각종 사진 기법을 전자화상시스템에서 구현한 Emulation 기능에 관한 것이다. 이는 기술적 성숙기에 있는 은염 방식의 사진 기술의 디지털화를 시도한 것으로서, 이를 위해 전자화상시스템의 구성하고, 은염사진과 디지털사진의 화상 형성 과정과 특성을 분석하고 실험을 수행하였다. 은염사진의 현상 인화 공정 등 각 공정의 모델링 및 분석을 수행하고, 전자 화상의 입출력 특성과 영상처리 기법과 비교하였으며, 스튜디오 및 야외 실사를 통한 은염필름과 CCD 촬상소자의 성능 분석 결과를 제시한다. 나아가서, 전자화상의 Emulation 기능의 설계에 대해 제안한다. A study on electronic imaging system with silver halide photography emulation is introduced. The study contains the comparison analysis between silver halide imaging process and electronic imaging process, the characterization of the detailed process in those imaging chains, such as exposure, developing, photographic print and the other photographic and digital process. As the first stage of study, we investigated the characteristic curve between optical density and the amount of exposure in silver halide and digital photography systems. Under wide range of exposure condition, several sensitometric parameters and the PSF(point spread function) were obtained via studio and outdoor photographic experiments with conventional photography and a digital camera. Also those experimental results will be shown. Finally, the design method for silver halide photography emulation and modeling the silver halide process will be discussed.

      • Efficacy and safety of guselkumab compared with placebo and adalimumab in Korean patients with moderate to severe psoriasis: Post-hoc analysis from the phase Ⅲ, double-blind, placebo- and active comparator-controlled VOYAGE1/2 trials

        ( Sang Woong Youn ),( Tae Yoon Kim ),( Byung Soo Kim ),( Seung Chul Lee ),( Jeung Hoon Lee ),( Yong-beom Choe ),( Joo-heung Lee ),( Jee-ho Choi ),( Joo Young Roh ),( Seong Jin Jo ),( Eun-so Lee ),( Mi 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

        Background: The Phase Ⅲ studies, VOYAGE 1 and 2, were conducted to assess guselkumab for the treatment of patients with moderate to severe psoriasis. However, these studies included a worldwide study population. Objectives: To determine the efficacy and safety of guselkumab in Korean patients. Methods: This analysis included 28 patients from VOYAGE 1 and 98 patients from VOYAGE 2. In total, 126 patients were analyzed. Outcomes through week 28 were analyzed due to differences in design after week28. Results: Of 126 Korean patients randomized, 30 received placebo, 63 were assigned to guselkumab, and 33 received adalimumab. Guselkumab was superior to adalimumab in achieving an IGA 0 score (clear skin) at week 12 (31.7% vs 0.0%, p<0.001) and at week 24 (52.4% vs 21.2%, p=0.004), respectively. Among patients treated with guselkumab, 40 of 63 (63.5%) achieved a PASI75 response at week 8; at week 24, a significantly higher proportion of guselkumab patients achieved a PASI 75 compared to adalimumab patients (93.7% vs 66.7%, respectively, p<0.001). In addition, higher proportions of guselkumab patients achieved PASI 90 and PASI 100 than adalimumab patients at week 24 (PASI90; 73.0% vs 57.6%, p=0.168 / PASI100; 20.6% vs 15.2%, p=0.591, respectively). Through week 28, guselkumab and adalimumab showed comparable safety profiles. Conclusion: The efficacy and safety of guselkumab in Korean psoriasis patients through 28 weeks was consistent with findings reported for the VOYAGE1 and 2 trials.

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