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Screening and Characterization of Microorganisms with Fibrinolytic Activity from Fermented Foods
(Myeong Ae Yu),(Gwan Sub Sim),(Seung Taek Kwon),(Jae Kwan Hwang),(Jung Kue Shin),(Ik Hyun Yeo),(Yu Rang Pyun),(Seon Joo Yoon) 한국미생물생명공학회 2002 Journal of microbiology and biotechnology Vol.12 No.4
N/A N/A
위식도 역류성 질환의 증상 소실 및 미란성 식도염 치유에 대한 에스오메프라졸 (esomeprazole) 20㎎ 및 40㎎의 효과를 평가하기 위한 공개, 다기관 공동 연구
김재준 ( Kim Jae Jun ),이선영 ( Lee Seon Yeong ),이풍렬 ( Lee Pung Lyeol ),명승재 ( Myeong Seung Jae ),김진호 ( Kim Jin Ho ),최명규 ( Choe Myeong Gyu ),김상우 ( Kim Sang U ),이오영 ( Lee O Yeong ),유종선 ( Yu Jong Seon ),주영은 ( 대한소화기기능성질환·운동학회 2003 Journal of Neurogastroenterology and Motility (JNM Vol.9 No.2
목적: PPI는 위식도 역류성 질환 환자의 식도 점막 손상에 대한 치유 및 증상 개선에 우수한 효과가 있어 치료제로 사용되고 있다. 최근에는 omeprazole보다 산억제 효과가 더 우수하다고 알려진 omeprazole의 S-isomer인 esomeprazole이 개발되어 처방되고 있으나, 아직 한국인에서는 그 효과에 대한 보고가 없다. 이에 연구자들은 한국인 위식도 역류성 질환 환자들에게 esomeprazole을 투여한 후, 식도염 치유율 및 증상 개 Background/Aims: Esomeprazole, an S-isomer of omeprazole, has a potent acid-suppressive effect. It has been prescribed for years, but no reported data had been available with respect to Korean patients. We evaluated the rate of symptom relief, healing rat
Bogie Fault Detections by Way of Condition-Based Monitoring of a Railway Vehicle
Myeong-Joon Kim,Jin-woo Yu,Hyeong-Ho Shin,Mohamad Aiman Hassan,Taehoon Kim,Hyun-Jik Cho,Nam-Jin Lee,Jae-Hwan Kim,Chul-Goo Kang 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10
In the modern railway industry, huge amount of money is invested for the maintenance of the railway system on yearly basis, in which failures or faults in components and systems have always been a major problem. An effective, efficient and reliable maintenance is required to ensure the efficiency, reliability and safety for the railway vehicles and give a high-quality service to the passengers. This paper presents bogie fault detection by way of the condition monitoring of the bogie in a railway vehicle, which addresses the logics for the model-based condition monitoring of suspension system using an extended Kalman filter. The presented logic has been demonstrated by simulation studies.
Caveolin‐1 deficiency induces premature senescence with mitochondrial dysfunction
Yu, Dong‐,Min,Jung, Seung Hee,An, Hyoung‐,Tae,Lee, Sungsoo,Hong, Jin,Park, Jun Sub,Lee, Hyun,Lee, Hwayeon,Bahn, Myeong‐,Suk,Lee, Hyung Chul,Han, Na‐,Kyung,Ko, Jesang,Lee, Jae BLACKWELL PUBLISHING 2017 AGING CELL Vol.16 No.4
<P><B>Summary</B></P><P>Paradoxical observations have been made regarding the role of caveolin‐1 (Cav‐1) during cellular senescence. For example, caveolin‐1 deficiency prevents reactive oxygen species‐induced cellular senescence despite mitochondrial dysfunction, which leads to senescence. To resolve this paradox, we re‐addressed the role of caveolin‐1 in cellular senescence in human diploid fibroblasts, A549, HCT116, and Cav‐1<SUP><I>−/−</I></SUP> mouse embryonic fibroblasts. Cav‐1 deficiency (knockout or knockdown) induced cellular senescence via a p53‐p21‐dependent pathway, downregulating the expression level of the cardiolipin biosynthesis enzymes and then reducing the content of cardiolipin, a critical lipid for mitochondrial respiration. Our results showed that Cav‐1 deficiency decreased mitochondrial respiration, reduced the activity of oxidative phosphorylation complex I (CI), inactivated SIRT1, and decreased the NAD<SUP>+</SUP>/NADH ratio. From these results, we concluded that Cav‐1 deficiency induces premature senescence via mitochondrial dysfunction and silent information regulator 2 homologue 1 (SIRT1) inactivation.</P>
Effect of High-Temperature in Photosystem II of Scion and Stock Commercial Tomato Cultivars
Yu Kyeong Shin,Shiva Ram Bhandari,Jae Woo Song,Myeong-Cheoul Cho,Eun Young Yang,Yul Kyun Ahn,Indeok Hwang,Jun Gu Lee 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10
This study was conducted to evaluate the chlorophyll fluorescence (CF) as well as growth performance for the detection of high-temperature treatment in the seedlings of one scion (Dafnis) and three stock cultivars of tomato (B-blocking, BKO, and Spider). Tomato seedlings at three-leaf stage were brought from seedling farm, and grown under warm white LED (220 ± 10 μmol·m<SUP>-2</SUP>·s<SUP>-1</SUP>) in a closed chamber having temperature (24/20°C), and light period 14/10 h (day/night) for 3 days. The seedlings were then grown under the three temperature levels [control: 24/20°C (day/night), High I: 32/28°C, and High II: 40/36°C] in a controlled condition for 6 days. Both the CF and growth parameters (number of leaves, height, fresh and dry weight of shoot, and diameter) were measured at 2-day interval during the experiment. Overall chlorophyll fluorescence kinetic in both the scion and stock cultivars was decreased in both High I and II treatment. Among the CF parameters, non-photochemical quenching (NPQ) and the ratio of the fluorescence decrease (Rfd) were the most influenced parameters showing significant decrement in both the high temperature treatments compared to the control during the progressive treatment time. In particular, the large stock varieties; B-blocking and BKO showed significant differences in effective quantum yield of photochemical energy conversion in PSII [Y(PSII)] and photochemical quenching of variable fluorescence based on the puddle model of PSII (qP) compared to Dafnis cultivar. Tomato seedlings exposed to high temperature showed straight leaf with dark in color, and reduced plant height and weight. The overall results showed that Y(PSII), qP, NPQ, and Rfd could be used to identify high temperature stress in tomato seedlings.
Yu Kyeong Shin,Shiva Ram Bhandari,Jae Woo Song,Myeong-Cheoul Cho,Eun Young Yang,Yul Kyun Ahn,Indeok Hwang,Jun Gu Lee 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10
To detect the injury caused by the low temperature in tomato seedlings, one scion (Dafnis) and three stock (B-blocking, BKO, and Spider) cultivars of tomato were used in this study, and their growth performance as well as chlorophyll fluorescence (CF) parameters were evaluated. For this, the seedlings at three-leaf stage were brought from seedling farm and grown under warm white LED (220 ± 10 μmol·m<SUP>-2</SUP>·s<SUP>-1</SUP>) in a constant environmental condition [temperature (24/20°C), and light period 14/10 h (day/night)] for 3 days for acclimatization to the new environment. Then, the seedlings were grown under the three temperature levels [control: 24/20°C (day/night), Low I: 16/12°C, and Low II: 8/4°C] in a closed and controlled plant production system for 6 days. Both the CF and growth parameters (number of leaves, height, fresh and dry weight of shoot, and diameter) were measured 2-day interval during the experiment. Among the CF parameters, minimal chlorophyll fluorescence intensity measured in the dark-adapted state (Fo), maximal chlorophyll fluorescence intensity measured in the dark-adapted state during the application of a saturating pulse of light (Fm), and maximum quantum yield of PSII photochemistry measured in the dark-adapted state (Fv/Fm) showed significant changes in both the low temperature treatments compared to the control during the progressive treatment time. Also, non-photochemical quenching (NPQ) and the ratio of the fluorescence decrease (Rfd) were influenced significantly. In particular, all the three stock cultivars exhibited significant differences in photochemical quenching of variable fluorescence based on the puddle model of PSII (qP). Overall growth performance was also affected significantly showing reduced growth rate, curling of leaves and nodes, and yellow leaf color. The selected CF parameters; Fo, Fm, Fv/Fm, NPQ, and Rfd could be used to detected low temperature stress in tomato seedlings.
Yu, Ha-Young,Lee, Sang-Min,Nam, Jae-Hoon,Lee, Seung-Joon,Fabrè,gue, Damien,Park, Myeong-heom,Tsuji, Nobuhiro,Lee, Young-Kook Elsevier 2017 Acta materialia Vol.131 No.-
<P>The objective of the present study was to elucidate the complicated interrelationship between necking, post-uniform elongation (e(pu)), strain rate sensitivity (SRS), fracture mechanism and Al concentration in Fe-18Mn-0.6C-xAl twinning-induced plasticity steels. Many tensile tests were conducted for in- and ex situ observations of necking, fracture surfaces, crack propagation and the density and size of micro-voids with the assistance of a high-speed camera and X-ray tomographic equipment. The addition of Al increased epu, SRS and reduction ratios in dimension of the neck part of tensile specimens, and also changed fracture mode from quasi-cleavage to ductile fracture at the edge part. The quasi-cleavage surface of Al-free specimen was induced by edge and side cracks occurring along grain boundary junctions and twin boundaries within the edges and side surfaces where local deformation bands meet. The ductile-fracture surface of 1.5 %Al-added specimen was formed by the coalescence of micro-voids. While the side-to-middle crack propagation occurred in Al-free and 1 %Al-added specimens due to side cracks, the middle-to-side crack propagation was observed in 1.5 %Al-added specimen. The Al-free specimen had the larger size of the 20 largest voids compared to the 1.5 %Al-added specimen despite its lower void density and local strain due to the accelerated growth of voids near the tips of side cracks. Evaluating the negligible epu of Al-free specimen by SRS is not deemed to be reasonable due to its inappreciable necking and side cracks. The improvement of epu in 1.5 %Al-added specimen is primarily due to disappearance of edge and side cracks. (C) 2017 Acta Materiali a Inc. Published by Elsevier Ltd. All rights reserved.</P>