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      • National Process of Quality Management Education : The Swedish Example

        Isaksson, Raine,Hansson, Jonas,Garvare, Rickard The Korean Society for Quality Management 2007 The Asian Journal on Quality Vol.8 No.2

        The application of a process view, as complement to the traditional functional division, is often a way to highlight organisational improvement potential. This paper examines the process of providing university level education in quality management, using Sweden as an example. The purpose is to assess the performance of university education as part of the supply chain of providing quality management to a society. This has been done by studying the actual offering compared to a notional benchmark of best performance. Preliminary results indicate that there could be a significant improvement potential in both providing more education of the right type and in the right way. A lot of similar basic courses are given but with varying names, possibly reflecting difficulties in defining the area of quality management and its constituents. An important reason for the detected improvement potential seems to be the lack of ownership of the studied supply chain of providing university level quality education to the Swedish society.

      • Process based system models - a stakeholder based improvement philosophy

        ( Raine Isaksson(phd) ) 한국품질경영학회 2015 한국품질경영학회 학술대회 Vol.2015 No.2

        Background The process approach is included in many improvement philosophies such as Six Sigma and Lean Management. Still, it seems that it has not been used to its full potential with many organisations having low process maturity. Visualising processes, stakeholder needs and opportunities could support the introduction of the process approach as a start for process based improvement. Purpose The purpose with this paper is to propose and to demonstrate the use of a process based system model. Methodology The starting point is in previous research on process based system models. A chosen model is reviewed and modified. The reviewed model is then tested in using it to describe global processes of providing accommodation and the sub-processes of producing cement and concrete. Findings The findings consist of proposed process models for detecting and realising opportunities for improvement. Results from the review of the process of providing accommodation indicate that the models can be used to detect opportunities. Practical implications The results provide a concept for visualising change and change elements. Originality/value The paper provides insights into process based improvement work and in synergies between quality and sustainability.

      • National Process of Quality Management Education: the Swedish Example

        ( Raine Isaksson ),( Jonas Hansson ),( Rickard Garvare ) 한국품질경영학회 2007 The Asian Journal on Quality Vol.8 No.2

        The application of a process view, as complement to the traditional functional division, is often a way to highlight organisational improvement potential. This paper examines the process of providing university level education in quality management, using Sweden as an example. The purpose is to assess the performance of university education as part of the supply chain of providing quality management to a society. This has been done by studying the actual offering compared to a notional benchmark of best performance. Preliminary results indicate that there could be a significant improvement potential in both providing more education of the right type and in the right way. A lot of similar basic courses are given but with varying names, possibly reflecting difficulties in defining the area of quality management and its constituents. An important reason for the detected improvement potential seems to be the lack of ownership of the studied supply chain of providing university level quality education to the Swedish society.

      • KCI등재

        Anti‑proliferative activity of a novel tricyclic triterpenoid acid from Commiphora africana resin against four human cancer cell lines

        Worku Dinku,Johan Isaksson,Fredrik Garnås Rylandsholm,Petr Bouř,Eva Brichtová,최상언,이상호,정영식,노재성,John Sigurd Mjøen Svendsen,Arne Jørgen Aasen,Aman Dekebo 한국응용생명화학회 2020 Applied Biological Chemistry (Appl Biol Chem) Vol.63 No.2

        Myrrh, a resin derived from the damaged bark of Commiphora genus, has traditionally been used for treatment of various human diseases, such as amenorrhea, ache, tumors, fever, and stomach pains. In spite of this widespread use of the myrrh in Ethiopia, the pharmacological activity and chemical composition have not been studied in detail. A new tricyclic triterpene acid (3S,4S,14S,7E,17E,21Z)-3,30-dihydroxypodioda-7,17,21-trien-4-carboxylic acid (commafric A) has been isolated from a crude methanolic extract of Commiphora africana (A. Rich.) Engl. resin along with the known pentacyclic triterpene α-amyrin. The structure of commafric A was characterized using different spectroscopic techniques such as 1D and 2D NMR, IR, and VCD combined with computations. The anti-proliferative activity of both isolated compounds was evaluated using SRB based colorimetric cellular assay against four human cancer cell lines. Etoposide was used as a positive control. Commafric A showed significant anti-proliferative effects against non-small cell lung cancer (A549) with IC50 values of 4.52 μg/ml. The pentacyclic triterpene α-amyrin showed a weak antiproliferative activity against A2780 (ovarian cancer), MIA-PaCa-2 (pancreatic cancer), and SNU638 (stomach cancer) cell lines tested with IC50 values ranging 9.28 to 28.22 μg/ml. Commafric A possessed anti-proliferative activity against non-small cell lung cancer (A549), which suggests that commafric A has potential to be further optimized being a lead compound in the search for new drugs against cancer diseases.

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