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Heesuk Kim,Hong Kyu Kim,Tyler Hyungtaek Rim,Ji Won Kim,Jin Hyung Kim,Sung Soo Kim 대한안과학회 2018 Korean Journal of Ophthalmology Vol.32 No.3
Purpose: This study aimed to investigate the diagnosis and severity of patients who were referred to tertiary medical centers according to the type and function of the referral hospitals. Methods: First-visit patients referred from July 2015 to June 2016 were retrospectively reviewed with regard to referral hospital, final diagnosis, treatment necessity, and medical fees for the six months after their first hospital visit. Based on these data, differences in type and function of medical institution were examined. Results: In a comparison of hospitals according to their number of beds, clinics, hospitals and, tertiary hospitals had no differences in the ratio of patients who needed treatment (p = 0.075) and their medical fees over six months (p = 0.372). When hospitals were classified by functional capability in terms of doctors’ medical specialty, increasing ratios of patients requiring medical treatment (p < 0.001) and medical fees for six months (p < 0.001) were found in the order of non-eye specialists, eye specialists, and eye specialists in trainee hospital. Conclusions: Efficient healthcare delivery systems should classify medical institutions by functionality capability based on medical specialties rather than hospital size according to the number of beds.
등온반응기와 단열반응기 조합으로 구성된 0.25 MW급 메탄합성 파일롯 공정 운전특성
김수현(Suhyun Kim),유영돈(Youngdon Yoo),강석환(Sukhwan Kang),류재홍(Jaehong Ryu),김진호(Jinho Kim),김문현(Munhyun Kim),고동준(Dongjun Koh),이현정(Hyunjung Lee),김광준(Gwangjun Kim),김형택(Hyungtaek Kim) 한국청정기술학회 2013 청정기술 Vol.19 No.2
본 연구에서는 등온반응기와 단열반응기로 구성된 0.25 MW 메탄합성 파일롯 공정 실험을 통한 운전 특성을 분석하였다. 등온반응기는 메탄합성 반응을 통해 발생하는 열을 포화수의 유량과 압력을 통해 강제적으로 제어할 수 있는 반응기로 등온반응기와 단열반응기를 조합할 경우 기존 단열반응기만으로 구성된 메탄합성 공정에 비해 반응기 개수를 줄일 수 있다. 또한 합성가스 재순환이 불필요하기 때문에 단열반응기 조합으로 구성된 메탄합성 공정에서 비용의 약 15~20%를 차지하는 재순환 압축기를 제거할 수 있다. 등온반응기로 유입되는 합성가스의 H2/CO 비가 3보다 낮은 경우에는 튜브에 충진된 촉매에 탄소 침적 현상이 일어나 반응기의 차압이 증가하였으며, H₂/CO 비가 3으로 공급되는 경우에는 탄소 침적 현상이 일어나지 않고 메탄합성 반응이 안정적으로 유지되어 CO 전환율 99% 이상, CH₄ 선택도 97% 이상, CH₄ 생산성 최대 695 ml/h·-cat를 얻을 수 있었다. In this study, we analyzed the operational characteristics of a 0.25 MW methanation pilot plant. Isothermal reactor controled the heat released from methanation reaction by saturated water in shell side. Methanation process consisting of isothermal reactor and adiabatic reactor had advantages with no recycle compressor and more less reactors compared with methanation process with only adiabatic reactors. In case that H2/CO ratio of syngas was under 3, carbon deposition occurred on catalyst in tube side of isothermal reactor and the pressure of reactors increased. In case that H₂/CO ratio was maintained around 3, no carbon deposition on catalyst in tube side of isothermal reactor was found by monitoring the differential pressure of reactors and by measuring the differential pressure of several of tubes filled with catalyst before and after operating. It was shown that CO conversion and CH₄ selectivity were over 99, 97%, respectively, and the maximum CH₄ productivity was 695 ml/h·g-cat.
Kim, Woo-Jin,Shin, Eun-Ha,Kong, Hee Jeong,Nam, Bo-Hye,Kim, Young-Ok,Jung, Hyungtaek,An, Cheul Min The Korean Society of Fisheries and Aquatic Scienc 2013 Fisheries and Aquatic Sciences Vol.16 No.4
Microsatellite markers are important for gene mapping and for marker-assisted selection. Sixty-five polymorphic microsatellite markers were developed with an enriched partial genomic library from olive flounder Paralichthys olivaceus an important commercial fish species in Korea. The variability of these markers was tested in 30 individuals collected from the East Sea (Korea). The number of alleles for each locus ranged from 2 to 33 (mean, 17.1). Observed and expected heterozygosity as well as polymorphism information content varied from 0.313 to 1.000 (mean, 0.788), from 0.323 to 0.977 (mean, 0.820), and from 0.277 to 0.960 (mean, 0.787), respectively. Nine loci showed significant deviation from the Hardy-Weinberg equilibrium after sequential Bonferroni correction. Analysis with MICROCHECKER suggested the presence of null alleles at five of these loci with estimated null allele frequencies of 0.126-0.285. These new microsatellite markers from genomic libraries will be useful for constructing a P. olivaceus linkage map.
Simulation of Vacuum Characteristics of High Vacuum System Modelled by VacCAD
Kim, Hyungtaek,Park, Junhyung,Yun, Gyeongah The Institute of Internet 2018 Journal of Advanced Smart Convergence Vol.7 No.4
In this paper, we simulated three different HV systems and analyzed of each vacuum characteristics by VacCAD modelling. In each of modelled vacuum systems, selection of chamber materials, combination of rough pump with high vacuum pump and conductance of roughing line (diameter and length) were proposed as system variables. In the modelling of chamber materials, the pumping times to ultimate pressures of different chamber materials (stainless steel, aluminum) were compared by the variations of chamber volume. In this model, the effects of outgassing dependent on the chamber materials was also simulated and aluminum was estimated to optimum chamber materials. It was also obtained that modelling of vane and roots pump with diffusion pump and diameter, length of $50{\times}250$ [mm]roughing line were characterized as optimum variables to reach the ultimate pressure of 10E-7 [mbar] most effectively. Optimum design factors for vacuum characteristics of modelled vacuum system were achieved by VacCAD simulations. Feasibility of VacCAD as vacuum simulator was verified and applications of VacCAD expected to be increased to fields in vacuum needed.
석탄 합성가스를 이용한 온도 및 압력변화에 대한 메탄화 반응 특성
김수현(Kim, Suhyun),유영돈(Yoo, Youngdon),류재홍(Ryu, Jaehong),변창대(Byun, Changdae),임효준(Lim, Hyojun),김형택(Kim, Hyungtaek) 한국신재생에너지학회 2010 한국신재생에너지학회 학술대회논문집 Vol.2010 No.11
석탄가스화로부터 얻어진 합성가스는 CO, H₂가 주성분으로, 그 자체를 연료로 사용하여 발전을 하거나 또는 적절한 정제, 분리 및 합성을 통해 다양한 원료물질을 생산할 수 있다. 이러한 석탄의 청정 사용 기술은 최근의 에너지 분야에서 많은 관심을 불러일으키고 있는 고유가 현상 및 석유자원 고갈에 대비할 수 있는 현실적인 방법의 하나로 여겨지고 있다. 석유를 대체할 에너지원으로서 석탄을 이용하는 다양한 응용 방법 중의 하나로 가스화 반응을 통해 발생하는 합성가스를 이용한 SNG 제조 공정을 들 수 있는데, 이는 석탄 등의 고체 시료를 이용하여 메탄이 주성분인 연료가스를 생산하는 것이다. SNG(Synthesis Natural Gas 또는Substitute Natural Gas)는 합성천연가스 또는 대체천연가스로 불리어지는데 주로 석탄의 가스화를 통해 얻어진 합성가스(syngas 또는 synthesis gas)인 CO, H₂를 촉매에 의한 합성반응을 통해 얻을 수 있다. SNG 합성 반응(메탄화 반응)은 보통 수성가스 전환 공정과 가스 정제 공정을 거친 합성가스를 CH₄로 전환하는 것으로 석탄을 이용한 SNG 제조 공정에서 가장 핵심 공정인 메탄화 반응은 높은 발열반응으로 주로 니켈 촉매를 사용하며 250{sim}400?C에서 반응이 이루어진다. SNG 합성 반응은 공급되는 합성가스의 조성(H₂/CO 비), 공급되는 합성가스의 유량과 반응기에 충진된 촉매의 부피와의 관계를 나타낸 공간속도, 반응온도 등의 조건에 따라 반응 특성이 달라질 수 있다. 가스화 반응을 통해 생성되는 합성가스를 이용한 SNG 합성반응(메탄화 반응)의 특성을 파악하기 위하여 Lab-scale 규모의 고정층 반응기를 이용하여 Ni 함량이 다른 2종류의 촉매를 대상으로 반응온도 및 압력에 따른 CO 전환율, CH₄ 선택도, CH₄ 생산성 변화를 파악하였다. 실험 결과 반응기의 온도가 350도 이상의 조건에서 CO 전환율은 99.8%이상, CH₄ 선택도는 90.7%이상으로 나타났으며, 공간속도가 2,000 1/h 이상의 조건에서는 CH₄ 생산성이 500 ml/g-cat, h을 만족하였다.
Jung, Hyungtaek,Yoon, Byung-Ha,Kim, Woo-Jin,Kim, Dong-Wook,Hurwood, David A.,Lyons, Russell E.,Salin, Krishna R.,Kim, Heui-Soo,Baek, Ilseon,Chand, Vincent,Mather, Peter B.,Lin, Li MDPI AG 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.5
<P>The giant freshwater prawn, <I>Macrobrachium rosenbergii</I>, a sexually dimorphic decapod crustacean is currently the world’s most economically important cultured freshwater crustacean species. Despite its economic importance, there is currently a lack of genomic resources available for this species, and this has limited exploration of the molecular mechanisms that control the <I>M. rosenbergii</I> sex-differentiation system more widely in freshwater prawns. Here, we present the first hybrid transcriptome from <I>M. rosenbergii</I> applying RNA-Seq technologies directed at identifying genes that have potential functional roles in reproductive-related traits. A total of 13,733,210 combined raw reads (1720 Mbp) were obtained from Ion-Torrent PGM and 454 FLX. Bioinformatic analyses based on three state-of-the-art assemblers, the CLC Genomic Workbench, Trans-ABySS, and Trinity, that use single and multiple <I>k</I>-mer methods respectively, were used to analyse the data. The influence of multiple <I>k</I>-mers on assembly performance was assessed to gain insight into transcriptome assembly from short reads. After optimisation, <I>de novo</I> assembly resulted in 44,407 contigs with a mean length of 437 bp, and the assembled transcripts were further functionally annotated to detect single nucleotide polymorphisms and simple sequence repeat motifs. Gene expression analysis was also used to compare expression patterns from ovary and testis tissue libraries to identify genes with potential roles in reproduction and sex differentiation. The large transcript set assembled here represents the most comprehensive set of transcriptomic resources ever developed for reproduction traits in <I>M. rosenbergii</I>, and the large number of genetic markers predicted should constitute an invaluable resource for future genetic research studies on <I>M</I>. <I>rosenbergii</I> and can be applied more widely on other freshwater prawn species in the genus <I>Macrobrachium</I>.</P>