운송업 종사 근로자의 건강가치 인식 및 건강증진 행위와 건강진단 결과와의 관련성

이선주,박정일,임현우,노영만,정치경 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.3

목 적 : 건강진단 결과 건강인과 요관찰자 및 일반질환자를 포함한 비건강인에서 건강가치인식 및 건강증진행위 실천정도를 알아보고, 건강인과 비건강인으로 층화한후 건강가치인식이 높은 군과 낮은 군에서 건강증진행위 실천에 차이가 있는지를 비교함으로써 바람직한 건강증진 프로그램 개발과 적용을 위한 기초자료를 제공하고자 수행되었다. 방 법 : 1998년도 건강진단을 받은 철도운송업 종사 근로자 4,919명중에서 자기기입식 설문에 응답한 건강인 233명, 요관찰자 172명, 일반질환자 160명을 연구대상으로 하였다. 결 과 . 삶의 가치 중 건강을 가장 가치있게 인식하고 있는 근로자가 건강인에서 37.3%, 비건강인에서 36.1%로 두 군간에 차이가 없었다. 건강증진 행위 실천에 있어 비 건강인이 건강인에 비하여 운동영역의 실천정도가 유의하게 낮았으며 대인관계 지지영역은 유의하게 높았다. 그 외의 영양, 스트레스관리, 자아실현 및 건강책임 관련 영역의 실천정도는 건강인과 비건강인 사이에 유의한 차이가 없었다. 건강인에서의 연령 변수를 제외하고 건강인 및 비건강인 모두 일반적 특성에 따른 건강가치 인식도에 차이가 없었다. 건강가치 인식도에 따른 건강증진행위 실천 정도는 건강인의 경우 건강가치 인식이 높은 군이 낮은 군에 비하여 자아실현 및 건강책임 영역의 실천 정도가 유의하게 높았으며, 비건강인의 경우 유의한 차이를 보이는 영역은 없었다. 결 론: 건강가치 인식, 건강증진행위 실천 정도와 건강진단 결과와의 관련성은 매우 낮게 나타나 건강증진 프로그램 개발과 적용에 있어 인식보다는 실천에 촛점을 두어야 될 것으로 판단된다. Objectives : This study was performed to compare health value cognition and health promotion behavior compliance between healthy group and not being healthy group, and to evaluate the difference of health promotion behaviors compliance between high group and low group in health value cognition. Methods . The subjecus of this study were 565 wor17ers, 233 healthy workers, 172 observation cases and 160 disease cases, selected from 4,919 transit coporation's workers. Results : In health promoting behavior compliance, not belng healthy group showed lower level than healthy group in exercise and showed higher level than healthy group in interpersonal support significantly. A worker who replied on "health" as the most value in life was consisted in 37.3% of healthy group and 36.1% of not belng healthy group, Health value cognition according to general characteristics showed no significant difference except only variable of age in healthy group. Health promoting behavior compliance according to cognition of health value showed in healthy group that a high level group of health value cognition was more significant difference than a low level group in self aclualization and health responsibility of health promoting behavior and didn't show difference significantly in not being healthy group. Conclusions : In conclusion, the relationship between health value cognition, health promotion behavior compliance and periodic health examination results showed weakly. Therefore, in order to develop and apply spontaneous health promotion program, it was considered that should emphasize compliance than cognition.

LC15-0133, a DPP IV Inhibitor: Efficacy in Various Animal Models

( Hyeon Joo Yim ) 한국응용약물학회 2008 학술대회 Vol.2008 No.1

태아폐를 닮은 폐 내배엽 종양 : 1예 보고 Report of a case

임현이,류한영,최호,임상현,소동문,이철주,심철,전미선 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

We report a case of pulmonary endodeimal tumor resembling fetal lung in a 35 year-old woman, who complained of cough with sputum for 6 months. Pulmonary endodermal tumor is a very rare neoplasm of the lung and it is exclusively composed of complex branching tubules resembling the canalicular stage of fetal lung, lacking sarcomatous component of pulmonary blastoma. Prognosis of this tumor after adequate resection appears to be better than that for biphasic pulmonary blastoma.

IgA신증에서 간질내 단핵세포 침윤 및 그 아형분포

정현주,임현이,성순희,최인준 대한병리학회 1994 Journal of Pathology and Translational Medicine Vol.28 No.5

Benign skin tumors on the plantar surface of the foot

( Hyeon Jeong Park ),( Yun Ho Lee ),( Junghwa Yang ),( Jung Yup Kim ),( Sunmin Yim ),( Jae Yun Lim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Tumors of the foot are rarely found in the general population. Most of the foot tumors are benign conditions, while malignant tumors are very rare to encounter. There are studies that have reported the relevance of mechanical stress and acral melanomas, but it’s relevance with benign tumors of the foot is still not clear. Objectives: To evaluate prevalence and correlation between types of tumors and weight bearing regions. Methods: A total of 87 patients were retrospectively evaluated. Based on the biopsy data, the type of tumor and its location in the foot were evaluated. Results: The distribution of benign tumors in weight bearing regions versus non-weight-bearing regions was calculated with the use of the chi-square godness-of-fit test. The p-value was less than 0.001 and the result was significant at p=<0.05. The most frequent anatomical location was sesamoids of 1st metatarsal bone (n=20, 22.99%), in order of frequency, tuberosity of calcaneus (n=18, 20.69%), heads of 2nd to 5th metatarsal bones (n=13, 14.94%). In terms of tumor type, among the non-tumors, the rates were higher in the order of epidermal cyst (n=26, 29.89%), dermatofibroma (n=9, 10.34%), hemangioma (n=8, 9.20%), eccrine poroma (n=6, 6.90%), ganglion cyst (n=3, 3.45%), vascular leiomyoma (n=2, 2.30%), lipoma (n=2, 2.30%). Conclusion: The data shows that understanding the relationship between the anatomical location and the type of tumor may be helpful in the diagnosis of tumor on the foot.

Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis.

Joo, Hyoe-Jin,Yim, Yong-Hyeon,Jeong, Pan-Young,Jin, You-Xun,Lee, Jeong-Eui,Kim, Heekyeong,Jeong, Seul-Ki,Chitwood, David J,Paik, Young-Ki Biochemical Society 2009 The Biochemical journal Vol.422 No.1

<P>Caenorhabditis elegans excretes a dauer pheromone or daumone composed of ascarylose and a fatty acid side chain, the perception of which enables worms to enter the dauer state for long-term survival in an adverse environment. During the course of elucidation of the daumone biosynthetic pathway in which DHS-28 and DAF-22 are involved in peroxisomal beta-oxidation of VLCFAs (very long-chain fatty acids), we sought to investigate the physiological consequences of a deficiency in daumone biosynthesis in C. elegans. Our results revealed that two mutants, dhs-28(tm2581) and daf-22(ok693), lacked daumones and thus were dauer defective; this coincided with massive accumulation of fatty acyl-CoAs (up to 100-fold) inside worm bodies compared with levels in wild-type N2 worms. Furthermore, the deficiency in daumone biosynthesis and the massive accumulation of fatty acids and their acyl-CoAs caused severe developmental defects with reduced life spans (up to 30%), suggesting that daumone biosynthesis is be an essential part of C. elegans homoeostasis, affecting survival and maintenance of optimal physiological conditions by metabolizing some of the toxic non-permissible peroxisomal VLCFAs from the worm body in the form of readily excretable daumones.</P>

Association between serum vitamin D level and psoriasis: A clinical review in Korean patients in a single tertiary center

( Hyeon Jeong Park ),( Yeon Gu Choi ),( Gyoo Huh ),( Yun Ho Lee ),( Junghwa Yang ),( Jung Yup Kim ),( Sunmin Yim ),( Heun Joo Lee ),( Young Jun Choi ),( Won-serk Kim ),( Ga-young Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: Psoriasis is a chronic, inflammatory autoimmune disease. Vitamin D (Vit D) is a hormone that may have important immunomodulatory effects in psoriasis. Some studies have demonstrated a relationship between Vit D deficiency and psoriasis. Objectives: We aimed to compare serum levels of Vit D of patient with active psoriasis and non-patient seen at the outpatient clinic. Methods: Based on the retrospective chart reviews, a total of 181 patients between April 2018 and Aug 2019 were observed. The analysis of Vit D serum levels was performed by immune-assay and according to recent report, values < 20ng/ml were considered deficiency, from 20 to < 30ng/ml insufficiency and ≥ 30ng/ml sufficiency. Statistical data were evaluated by Chi-Square test and the values were considered significant when P < 0.05. Results: In psoriasis group (n=83, 26 females and 57 males), mean age was 42.04 and patients with serum Vit D deficiency was 59.04% (n=49). In non-psoriasis group (n=98, 46 females and 52 males), mean age was 43.60 and the frequency of serum Vit D deficiency was 71.43% (n=70). There was no statistically significant difference between the two groups (p=.080, > 0.05). However, serum Vit D level and the PASI showed a negative correlation (R=-0.134), although the relationship was weak. Conclusion: We observed that there was no significant differences in serum Vit D level between two groups. Further study is needed considering age, gender, comorbidity associated with disease severity.

Determination of Dibutyltin in Sediments Using Isotope Dilution Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry

Yim, Yong-Hyeon,Park, Ji-Youn,Han, Myung-Sub,Park, Mi-Kyung,Kim, Byung-Joo,Lim, Young-Ran,Hwang, Eui-Jin,So, Hun-Young Korean Chemical Society 2005 Bulletin of the Korean Chemical Society Vol.26 No.3

A method is described for the determination of dibutyltin (DBT) in sediment by isotope dilution using liquid chromatography inductively-coupled plasma/mass spectrometry (LC-ICP/MS). To achieve the highest accuracy and precision, special attentions are paid in optimization and evaluation of overall processes of the analysis including extraction of analytes, characterization of the standards used for calibration and LC-ICP/MS conditions. An approach for characterization of natural abundance DBT standard has been developed by combining inductively-coupled plasma/optical emission spectrometry (ICP/OES) and LC-ICP/MS for the total Sn assay and the analysis of Sn species present as impurities, respectively. An excellent LC condition for separation of organotin species was found, which is suitable for simultaneous DBT and tributyltin (TBT) analysis as well as impurity analysis of DBT standards. Microwave extraction condition was also optimized for high efficiency while preventing species transformation. The present method determines the amount contents of DBT in sediments with expanded uncertainty of less than 5% and its result shows high degree of equivalence with reference values of an international inter-comparison and a certified reference material (CRM) within stated uncertainties.

Treatment of nail psoriasis with pulsed dye laser and picosecond Nd:YAG laser: a pilot study

( Hyeon Jeong Park ),( Yeon Gu Choi ),( Gyoo Huh ),( Yun Ho Lee ),( Junghwa Yang ),( Jung Yup Kim ),( Sunmin Yim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Nail involvement is prevalent in psoriasis, and affects over 50% of patients with psoriasis. The treatment of nail psoriasis is challenging, and the gold standard treatment for nail psoriasis is not yet established. Recently, several studies have shown that the microsecond 1064-nm Nd:YAG laser has been successful in treating onychodystrophy. Also, there are reports that pulsed dye laser (PDL) was effective for the improvement of nail psoriasis. We performed a left-to-right split study, and irradiated both nails with a picosecond 1064-nm Nd:YAG laser and PDL. Therefore, we compared the clinical improvement of two laser devices in three patients with nail psoriasis. A decrease in NAPSI score in both nail matrix and nail bed was observed with both treatments. Clinical improvement of nail psoriasis was theoretically due to the destruction of abnormal vasculature, collagen rejuvenation of the nail matrix, nail bed, and proximal nail fold. And we also hypothesized that increased local blood circulation and triggered immune reactions in the nail apparatus improve the nail matrix function. We experienced the temporary improvement with the use of PDL and picosecond 1064-nm Nd:YAG laser in the treatment of nail psoriasis. We need a prospective study designed with a larger number of patients, and a longer follow-up period.

Chronic skin wounds successfully treated with a new negative pressure device

( Hyeon Jeong Park ),( Yeon Gu Choi ),( Gyoo Huh ),( Yun Ho Lee ),( Junghwa Yang ),( Jung Yup Kim ),( Sunmin Yim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Wounds that do not heal within three months are defined as chronic skin wounds. Here we introduce several cases of chronic skin wounds successfully treated with a new negative pressure wound therapy (NPWT) device. We treated patients using a NPWT dressing (PICO™, Smith and Nephew, Hull, UK), which has the advantages of portable size, lower cost, and higher patient compliance. This device has a lighter pad consisting of four layers which retains exudate and bacteria instead of the heavy canister. Three patients with chronic skin wounds were applied with this device who had various traumatic wounds. A minimum of four weeks follow-up was required until healed. Using this NPWT device, the epithelium was regenerated more rapidly and showed marked reduction of exudates such as seroma and hematoma. We experienced rapid clinical improvement by applying new NPWT device to chronic wound patients who did not respond well to conventional dressing therapy. It has no canister which could increase patient compliance, is noninvasive, and shows rapid improvement only with outpatient treatment. This new device is expected to be applicable to a variety of diseases in the field of dermatologic surgery.