한국과 일본 대학생의 스포츠상황에 대한 도덕적 가치판단수준 비교

함정혜(Chung Hae Hahm) 한국여성체육학회 2013 한국여성체육학회지 Vol.27 No.1

The purpose of this study was to compare the differences of moral reasoning among general students, sports related majors students, and student athletes in Korea and Japan University. We collected total 612 out of 700 (315 from Korea, 297 from Japan) and 88 questionnaires were excluded questionnaire due to incompleteness and unreliable data. For this study, Hahm-Bellar Values Choice Inventory-16(HBVCI-16), which is a Moral Reasoning Questionnaire on Sports Activities, was used. The collected data was analyzed by t-test, one way ANOVA and two way ANOVA with using SPSS Var. 17.0 statistical package program and result were as follow. First, the Japan student`s overall score of moral reasoning were lower compare to Korean university students. Second, there were 1 % higher score of moral reasoning in woman against man and in younger subjects. Sports majored university students presented 1% higher score against other related students and higher grade students presented 5% higher score against lower grade students. Third, among student athletes of Korea and Japan, although there were no significant differences, it was 0.1% higher among those who engaged in individual sports and 5% higher score in those who have less sports career.

A Model for Computer-Aided Process Planning System in Flexible Manufacturing Systems

Kang, Young-Sig,Hahm, Hyo-Joon,Rim, Suk-Chul,Kim, Seung-Baum The Korean Society for Quality Management 1994 품질경영학회지 Vol.22 No.1

Most of computer-aided process planning(CAPP) systems have been developed to automate the process planning function. In this paper, we describe an analytical model for a CAPP system in order to improve the performance of production system in flexible manufacturing systems(FMSs) for computer intergrated manufacturing(CIM) architecture. This paper proposes an optimal process planning that minimizes the load time by minimizing the cycle time and the number of workstations using Kang and Hahm's heuristic approach so as to improve the performance of production system under the batch production of discrete products. We also perform simulation using SIMAN language to campare the line utilization of each for various product types. The proposed algorithm can be implemented in existing FMSs for on-line control of product quantity using programmable logic controllers(PLC) and communication devices.

호남지방 경제사의 연구사적 검토 : 구한말에서 일제시대에 이르는 시기에 관한 연구를 중심으로

함한희 한국문화인류학회 1994 韓國文化人類學 Vol.25 No.1

Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein

Hahm, Young Hye,Hahm, Sung Ho,Jo, Hyoun Young,Ahn, Yeong Hee Hindawi 2018 International journal of analytical chemistry Vol.2018 No.-

<P>Glycosylation is one of the most important posttranslational modifications for proteins, including therapeutic antibodies, and greatly influences protein physiochemical properties. In this study, glycopeptide mapping of a reference and biosimilar recombinant antibodies (rAbs) was performed using liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) and an automated Glycoproteome Analyzer (GPA) algorithm. The tandem mass analyses for the reference and biosimilar samples indicate that this approach proves to be highly efficient in reproducing consistent analytical results and discovering the implications of different rAb production methods on glycosylation patterns. Furthermore, the comparative analysis of a mutagenized rAb glycoprotein proved that a single amino acid mutation in the Fc portion of the antibody molecule caused increased variations in glycosylation patterns. These variations were also detected by the mass spectrometry method efficiently. This mapping method, focusing on precise glycopeptide identification and comparison for the identified glycoforms, can be useful in differentiating aberrant glycosylation in biosimilar rAb products.</P>

고등학생의 체육활동을 통한 도덕적 가치판단과 도덕성발달단계와의 관계에 관한 연구

함정혜(Chung Hae Hahm) 한국여성체육학회 2005 한국여성체육학회지 Vol.19 No.4

우리나라 企業의 經營合理化를 위한 硏究 : 航空企業體 勤勞者의 意識構造分析을 中心으로

咸根培,咸永勳 한국항공대학교 1980 論文集 Vol.17 No.-

우리는 새로운 韓國的 企業觀과 構成員의 價値意識의 探索이 切實히 要請되고 있다. 이러한 問題는 具體的으로 勞使協調增進, 人間關係改善, 生産性提高, 原價節減, 從業員의 厚生福祉의 增進, 分任討議, 經營陣과 從業員의 意識構造改善으로 해결될 수 있을 것이다. Careful Studies on the Koreanized new concept of enterprise and the valuation sensen of all participating members are requested. Those problems will be solved through the improvement of labor-enterprise coordination, betterment of human relations, productivity promotion, cost reduction, improvement of labor welfare system, homogenions group discussions, and betterment of thinking pattern of manager group and labor.

A Hybrid Approach to English Verb Phrase Ellipsis

Hahm Hyun?Jong 새한영어영문학회 2010 새한영어영문학 Vol.52 No.2

Verb Phrase Ellipsis (VPE, hereafter) is a complex phenomenon where a verb phrase (VP) constituent does not appear under some kind of identity with another VP in the discourse (Potsdam 1997: 353). This research gives an analysis of VPE in English finite clauses. The various circumstances of VPE are permitted in systematic ways. I mainly adopt the analyses given by Lasnik (1995, 1999) in the hybrid lexical properties towards main verbs versus auxiliary verbs and Kim (1998, 2000) in different lexical types of the negative word not. The analysis of this paper is given in the generative framework. This paper accounts for VPE in English finite clauses under the following claims. First, main verbs in English are bare in the lexicon while auxiliary verbs have and be are fully inflected, following Lasnik’s (1995, 1999) theory. Second, VPE is permitted when it shows morphological identity between the target VPs and their antecedents; and the elided target VPs are c-commanded by T. Unlike Lasnik’s theory, the stranded affix filter is not supported in this paper. Third, the English negated word not is analyzed as either the head of NegP, which takes TP as a complement phrase, or an adverb adjoining to V’ or Asp’, following Kim’s (1998) analysis in the non-transformational approach. Unlike the Neg head not, the negated word not, including any other adverbs, cannot be stranded due to their semantic interpretation. The apparently complicated VPE phenomenon is analyzed systematically by the different lexical properties of the words in the syntactic phrase structures.

In Vitro Formation of Active Carboxypeptidase Y from Pro-Carboxypeptidase Y Inclusion Bodies by Fed-Batch Operation

HAHM, MOON SUN,CHUNG, BONG HYUN 한국미생물 · 생명공학회 2001 Journal of microbiology and biotechnology Vol.11 No.5

The gene encoding yeast pro-carboxypeptidase Y (pro-CPY) has been cloned and expressed in Escherichia coli. Most of the expressed pro-CPY was accumulated as cytoplasmic insoluble aggregates. In our previous study [3], active CPY was obtained by renaturation of entirely denatured pro-CPY followed by in vitro proteolytic processing with proteinase K along with the activation process. The same refolding process was performed to produce an active CPY from pro-CPY inclusion bodies with renaturation buffers containing proteinase K at different concentrations. The refolding efficiency decreased from 25% to 2% in the renaturation buffers containing proteinase K at concentrations of 60㎍/ml and 0.6㎍/ml, respectively. In an attempt to increase the refolding efficiency with a lesser amount of proteinase K, a novel fed-batch refolding process was developed. In a fed-batch refolding, 99 ml of the renaturation buffer containing pro-CPY was gradually added into I ml of the renaturation buffer containing 60 ㎍/ml of proteinase K to give a final proteinase K concentration of 0.6 ㎍/ml. The fed-batch refolding process resulted in a refolding efficiency of 18%, which corresponded to a 9-fold increase over that (2%) in the batch process.

Characterization of the Nickel Resistance Gene from Legionella pneumophila : Attenuation of Nickel Resistance by ppk(polyphosphate kinase) Disruption in Escherichia coli

Hahm, Dae Hyun,Yeom, Mi Jung,Ko, Whae Min,Lee, Eunjoo H.,Lee, Hye Jung,Shim, In Sop,Kim, Hong Yeoul 한국미생물 · 생명공학회 2002 Journal of microbiology and biotechnology Vol.12 No.1

A 1,989-bp genomic region encoding nickel resistance genes was isolated from Legionella pneumophila, a pathogen for legionellosis. From a sequencing and computer analysis, the region was found to harbor two structural genes, a nreB-like protein gene (1,149 bp) and a nreA-like protein gene (270 bp), in a row. Both genes exhibited a significant degree of similarity to the corresponding genes from Synechocystis sp. PCC6803 (54% amino acid sequence identity) and Achromobacter xylosoxidans 31A (76%). The gene was successfully expressed in E. coli MG1655 and conferred a nickel resistance of up to 5mM in an LB medium and 3 mM in a TMS medium including gluconate as the sole carbon source. E. coli harboring the nickel resistance gene also exhibited a substantial resistance to cobalt, yet no resistance to cadmium or zinc. Since the extracellular concentration of nickel remained constant during the whole period of cultivation, it was confirmed that the nickel resistance was provided by an efflux system like the Ni^2+ permease (nrsD) of Synechocystis sp. strain PCC6803. Since polyphosphate (poly-P) is known as a global regulator for gene expression as well as a potential virulence factor in E. coli, the nickel resistance of a ppk mutant of E. coli MG1655 harboring the nickel resistance gene from L. pneumophila was compared with that of its parental strain. The nickel resistance was significantly attenuated by ppk inactivation, which was more pronounced in an LB medium than in a TMS medium.

Modulation of Presynaptic GABA Release by Oxidative Stress in Mechanically-isolated Rat Cerebral Cortical Neurons

Hahm, Eu-Teum,Seo, Jung-Woo,Hur, Jin-Young,Cho, Young-Wuk The Korean Society of Pharmacology 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.3

Reactive oxygen species (ROS), which include hydrogen peroxide ($H_2O_2$), the superoxide anion (${O_2}^-{\cdot}$), and the hydroxyl radical ($OH{\cdot}$), are generated as by-products of oxidative metabolism in cells. The cerebral cortex has been found to be particularly vulnerable to production of ROS associated with conditions such as ischemia-reperfusion, Parkinson's disease, and aging. To investigate the effect of ROS on inhibitory GABAergic synaptic transmission, we examined the electrophysiological mechanisms of the modulatory effect of $H_2O_2$ on GABAergic miniature inhibitory postsynaptic current (mIPSCs) in mechanically isolated rat cerebral cortical neurons retaining intact synaptic boutons. The membrane potential was voltage-clamped at -60 mV and mIPSCs were recorded and analyzed. Superfusion of 1-mM $H_2O_2$ gradually potentiated mIPSCs. This potentiating effect of $H_2O_2$ was blocked by the pretreatment with either 10,000-unit/mL catalase or $300-{\mu}M$ N-acetyl-cysteine. The potentiating effect of $H_2O_2$ was occluded by an adenylate cyclase activator, forskolin, and was blocked by a protein kinase A inhibitor, N -(2-[p-bromocinnamylamino] ethyl)-5-isoquinolinesulfonamide hydrochloride. This study indicates that oxidative stress may potentiate presynaptic GABA release through the mechanism of cAMP-dependent protein kinase A (PKA)-dependent pathways, which may result in the inhibition of the cerebral cortex neuronal activity.