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Measurement of Deuteron Induced Thick Target Neutron Yields at 9 MeV
N. Shigyo,K. Hidaka,K. Hirabayashi,Y. Nakamura,D. Moriguchi,M. Kumabe,H. Hirano,S. Hirayama,Y. Naitou,C. Motooka,C. Lan,T. Watanabe,Y. Watanabe,K. Sagara,S. Maebaru,H. Sakaki,H. Takahashi 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
The double differential thick target neutron yields from 9 MeV deuteron incidence were measured at the Kyushu University Tandem Accelerator Laboratory. A copper and a titanium foils which are thick enough for a deuteron to stop in the foils were placed at the center of a vacuum chamber. An NE213 liquid organic scintillator was employed to detect neutrons emitted from targets and placed at 9 directions from 0˚ to 140˚. To consider the contribution of scattered neutrons from the floor, we also measured neutron yields with an iron shadow bar located in front of the scintillator. Because incident deuteron beam was not pulsed and the Time-of-Flight method was not applied, the energy spectrum was derived from unfolding the light output spectrum using the FORIST code. The detection efficiency was calculated with the SCINFUL-QMD code. The experimental results were compared with the calculation data of the TALYS code, and it turned out that the calculation data does not reproduce the experimental ones satisfactorily.
Hirano, Y.,Yokota, H.,Kita, K. Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.4
Previously, we reported that a diet including sesame meal (SM) increased plasma total and high-density lipoprotein (HDL)-cholesterol concentrations in goats. In the present study, the components in the sesame meal that can increase plasma total and HDL-cholesterol concentrations have been examined. In experiment 1, we gave goats defatted sesame meal diet (DSM) to investigate the influence of ether extract fraction remained in sesame meal. Corn gluten meal diet (CGM) was also fed to goats as a high-protein diet to examine the influence of high dietary protein level caused by usage of sesame meal. Plasma total and HDL-cholesterol concentrations of goats fed DSM and CGM did not change during experimental periods though they were elevated by feeding SM. In experiment 2, the influence of sesame oil and corn oil added in diets on plasma total and HDL-cholesterol concentrations in goats was investigated. Plasma total and HDL-cholesterol concentrations were increased by feeding both corn oil diet and sesame oil diet. In conclusion, the increase in plasma HDL-cholesterol concentration by feeding sesame meal was resulted by the effect of ether extract fraction including sesame oil or some lipid-soluble components remained in sesame meal.
Dietary Sesame Meal Increases Plasma HDL-cholesterol Concentration in Goats
Hirano, Y.,Kashima, T.,Inagaki, N.,Uesaka, K.,Yokota, H.,Kita, K. Asian Australasian Association of Animal Productio 2002 Animal Bioscience Vol.15 No.11
Influence of dietary sesame meal on plasma glucose, non-esterified fatty acid (NEFA), triglyceride, total cholesterol, high-density lipoprotein (HDL)-cholesterol and urea concentrations in goats was examined. Goats were fed a control diet (50% timothy hay and 50% concentrates) (CD) or a sesame meal diet (50% timothy hay, 25% concentrates and 25% sesame meal) (SMD) during 12 days. Blood samples were taken after overnight fasting and afternoon every day. Body weight was not changed by feeding either CD or SMD. The concentrations of plasma triglyceride and urea were higher (p<0.05) in goats fed SMD than those fed CD. Plasma NEFA concentration was higher in plasma samples after overnight fasting. Plasma glucose concentration in plasma samples collected afternoon was higher than those after overnight fasting. Plasma total cholesterol concentration was significantly increased by feeding SMD but not by feeding CD, which was due to the remarkable increase of plasma HDL-cholesterol concentration. In conclusion, dietary sesame meal brought about an increase in plasma total cholesterol concentration accompanied with an increment in plasma HDL-cholesterol consentration in goats.
Lu, Y.,Kim, H.C.,Lee, Je Hyun,Oh, Myung Hoon,Wee, Dang Moon,Hirano, Toshiyuki Trans Tech Publications, Ltd. 2006 Materials science forum Vol.510 No.-
<P>Directional or single crystal technique was applied to enhance the ductility, and two phases of γ (Ni) phase or β (NiAl) phase in γ‘(Ni3Al) matrix were also considered to increase the strength and ductility. In this study, directionally solidified rods were prepared at the solidification rate of 50µm/s in 23-27 at.% Al-Ni alloys, and tensile strengths of these rods were analyzed at room temperature. Directionally solidified samples showed the γ dendrite fibers formed in the Ni3Al matrix in the hypo eutectic composition of 23 at.% Al, the γ‘ single phase in the eutectic composition of 24.5 at. % Al, and the β dendrite fibers in the γ‘ matrix in the hyper eutectic compositions of 25, 26, 27 at.% Al. The hypoeutectic alloy including γ dendrites with γ‘ matrix exhibited a large elongation of over 70% with ductile transgranular fracture at room temperature. With increasing Al contents, the γ dendritic microstructure changed to the β dendrite in the γ‘ matrix, which resulted in decreasing the elongation by increasing the volume fraction of the brittle β dendrites in the ductile γ’ matrix.</P>
Abe, K.,Hieda, K.,Hiraide, K.,Hirano, S.,Kishimoto, Y.,Kobayashi, K.,Moriyama, S.,Nakagawa, K.,Nakahata, M.,Ogawa, H.,Oka, N.,Sekiya, H.,Shinozaki, A.,Suzuki, Y.,Takeda, A.,Takachio, O.,Ueshima, K.,Um North-Holland Pub. Co 2013 Physics letters: B Vol.719 No.1
A search for light dark matter using low-threshold data from the single phase liquid xenon scintillation detector XMASS, has been conducted. Using the entire 835 kg inner volume as target, the analysis threshold can be lowered to 0.3 keVee (electron-equivalent) to search for light dark matter. With low-threshold data corresponding to a 5591.4 kg@?day exposure of the detector and without discriminating between nuclear-recoil and electronic events, XMASS excludes part of the parameter space favored by other experiments.
Iida, M.,Fujii, S.,Uchida, M.,Nakamura, H.,Kagami, Y.,Agusa, T.,Hirano, M.,Bak, S.M.,Kim, E.Y.,Iwata, H. Elsevier/North Holland Biomedical Press 2016 Aquatic toxicology Vol.177 No.-
<P>2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces a broad spectrum of toxic effects including craniofacial malformation and neural damage in fish embryos. These effects are mainly mediated by the aryl hydrocarbon receptor (AHR). However, the mode of action between TCDD-induced AHR activation and adverse outcomes is not yet understood. To provide a comprehensive picture of the AHR signaling pathway in fish embryos exposed to TCDD, red seabream (Pagrus major) embryos were treated with graded concentrations of TCDD (0.3-37 nM) in seawater, or with a mixture of TCDD and 500 nM CH223191, an AHR-specific antagonist. The transcriptome of red seabream embryos was analyzed using a custom-made microarray with 6000 probes specifically prepared for this species. A Jonckheere-Terpstra test was performed to screen for genes that demonstrated altered mRNA expression levels following TCDD exposure. The signals of 1217 genes (as human homologs) were significantly altered in a TCDD concentration-dependent manner (q-value < 0.2). Notably, the TCDD-induced alteration in mRNA expression was alleviated by co-exposure to CH223191, suggesting that the mRNA expression level of these genes was regulated by AHR. To identify TCDD-activated pathways, the microarray data were further subjected to gene set enrichment analysis (GSEA) and functional protein-protein interaction (PPI) network analysis. GSEA demonstrated that the effects of TCDD on sets of genes involved calcium, mitogen-activated protein kinase (MAPK), actin cytoskeleton, chemokine, T cell receptor, melanoma, vascular endothelial growth factor (VEGF), axon guidance, and renal cell carcinoma signaling pathways. These results suggest the hypotheses that TCDD induces immunosuppression via the calcium, MAPK, chemokine, and T cell receptor signaling pathways, neurotoxicity via VEGF signaling, and axon guidance alterations and teratogenicity via the dysregulation of the actin cytoskeleton and melanoma and renal cell carcinoma signaling pathways. Furthermore, the PPI network analysis indicated that the adverse outcome pathways of TCDD in the embryos might be propagated through several hub genes such as cell division control protein 42, phosphoinositide-3-kinase regulatory subunit 1, and guanine nucleotide binding proteins. Understanding these pathways potentially allows for exploring the adverse outcome pathway of the effects of TCDD on the red seabream embryos. (C) 2016 Elsevier B.V. All rights reserved.</P>