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      • KCI등재

        Peroneal Nerve Dysfunction in Patients with Clubfoot Deformity: Evaluation of Clinical Presentation and Treatment

        Parmanand Gupta,Bharath Patil,Prakash Gupta,Rohil Mehta,Ravi Gupta 대한정형외과학회 2021 Clinics in Orthopedic Surgery Vol.13 No.4

        Background: Complete peroneal nerve dysfunction associated with congenital clubfoot is uncommonly reported. Our retrospective study highlights the recognition of clinical presentation and mid-term outcomes of treatment in these patients. Methods: Eight out of 658 patients undergoing treatment for clubfoot were identified with unilateral complete peroneal nerve dysfunction associated with congenital clubfoot. Three patients presented primarily to our center; 5 were treated elsewhere initially. All patients were treated with Ponseti casts, Achilles tenotomy, and subsequent foot abduction bracing. Diagnosis of complete peroneal nerve dysfunction was confirmed using nerve conduction velocity studies in all patients. After full-time bracing, an insole polythene molded ankle foot orthosis was given. Three patients underwent tibialis posterior transfer to improve foot dorsiflexor power. Results: The mean age at presentation was 1.3 years (range, 1 week–5 years). All patients had prominence of lateral 3 metatarsal heads and dimpling of intermetatarsal spaces. At a mean follow-up of 5.1 years, mean shortening of 1.2 cm in tibia (range, 1–2.5 cm) and mean calf wasting of 4.4 cm were observed. There was no relapse of any clubfoot deformity till the final follow-up. Conclusions: Prominence of lateral metatarsal heads and dimpling of intermetatarsal spaces should raise early suspicion of peroneal nerve dysfunction. Standard Ponseti protocol is useful in treatment of these patients. Tibialis posterior transfer to dorsum partially restores the ankle dorsiflexion.

      • KCI등재

        Phytochemicals and biological studies on Cycas revoluta Thunb.: a review

        Prakash Vinit,Kaur Harpreet,Kumari Anjana,Kumar Manoj,Bala Ritu,Gupta Sumeet 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.3

        This review article on Cycas revoluta mainly comprehensively summarizes characterization, morphology, distribution, traditional uses, phytochemical constituents and biological activities of isolated individual constituents as well as plant extract. Cycas revoluta is commonly known as Sago palm which belongs to gymnosperm species, cycadaceae family and has been used as a traditional medicine to cure blood vomiting, flatulence, skin diseases, hypertension, gastrointestinal distress, cough, blood pressure, hair growth, astringent, diuretic, snake bite, dressing wounds, swollen glands and stomach purifying. Its phytochemical analysis have been revealed the presence of flavonoids, glycosides, non-protein amino acids, fatty acids, benzenoids, terpenes, amino acids, diterpenoids, triterpenoids, sterols, esters and steroids. The chemical constituents and crude extracts exhibit biological activities such as antimicrobial, antioxidant, cytotoxic, antileishmanial, anticancer and many more.

      • KCI등재
      • KCI등재후보

        REtrospective Multicenter INdian Study of Derivo Embolization Device (REMIND): Periprocedural Safety

        Niranjan Prakash Mahajan,Mudasir Mushtaq,Amit Bhatti,Sukalyan Purkayastha,Nitin Dange,Mathew Cherian,Vipul Gupta,Vikram Huded 대한신경중재치료의학회 2021 Neurointervention Vol.16 No.3

        Purpose: The treatment of aneurysms with characteristics such as complex morphology, fusiform, blister-like, wide neck, or large size has been revolutionized with the introduction of flow diverters. Though flow diverters have several advantages over coiling, they also have certain important disadvantages such as the lack of immediate protection against rupture, the risk of ischemic stroke, the need for antiplatelet therapy, and long latency for complete effect. The Derivo Embolization Device (DED) is a second-generation self-expanding device that is claimed to be less thrombogenic than conventional devices. We retrospectively evaluated the periprocedural safety and risks associated with the DED across 5 centers in India. Materials and Methods: This is a multicentric, retrospective, observational study of DED, conducted at 5 high volume endovascular therapy centers in India from May 2018 to June 2020. Periprocedural demographic, clinical, and angiographic data were collected from a retrospective review of patient charts. Results: A total of 96 patients, including 56 (58.3%) females, aged between 16–80 years (60±12.7 years) harboring 106 aneurysms were studied. Seven (7.3%) were noted to harbor multiple aneurysms: 6 had 3 aneurysms each, while 1 patient had 5 aneurysms. The following aneurysm characteristics were noted: average size, 9.8±8.2 mm; average neck size, 6.9±8.5 mm; wide-necked (>4 mm), 63 (59.4%); giant (>25 mm), 8 (7.5%); and anterior circulation location, 98 (92.5%). Eighteen (17%) of these were ruptured. Additional balloon angioplasty was performed in 5 (5.2%) patients. Intraprocedural problems were encountered in 3 (3.1%), of which only 1 had clinical implications, the device fish-mouthing with stent thrombosis resulting in a malignant middle cerebral artery territory infarction. The modified Rankin scale at 3 months was worse in 1 patient. Conclusion: DED is a newer generation flow diverter stent with a low periprocedural complication rate.

      • KCI등재

        Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis

        ( Akshita Gupta ),( Sawan Bopanna ),( Saurabh Kedia ),( Dawesh Prakash Yadav ),( Sandeep Goyal ),( Saransh Jain ),( Govind Makharia ),( Vineet Ahuja ) 대한장연구학회 2017 Intestinal Research Vol.15 No.3

        Background/Aims: Familial occurrence of inflammatory bowel disease (IBD) is well documented. Reports from Western countries have shown a higher familial occurrence of ulcerative colitis (UC) in first- and second-degree relatives than that in the Asian UC population. No data are currently available from the Indian subcontinent in this regard. We present our data on the familial aggregation of UC. Methods: Records of patients with UC followed at the Inflammatory Bowel Disease Clinic at the All India Institute of Medical Sciences, New Delhi from August 2004 to January 2016 were reviewed. Details regarding the prevalence of family history and characteristics of these patients were recorded. Affected family members were contacted and disease characteristics were noted for assessment of familial aggregation. Results: Of the 2,058 UC patients included in the analysis, a positive family history of IBD was confirmed in 31 patients (1.5%), 24 (77.4%) of whom had only first-degree relatives affected. All the affected relatives had UC and none had Crohn`s disease. Among first-degree relatives, siblings were found to have the highest prevalence of IBD (53.3%), followed by parents (26.7%). Conclusions: The probability of occurrence of IBD in family members of affected North Indian UC patients is lower than that reported in Western populations. (Intest Res 2017;15:388-394)

      • KCI등재

        Bibliometric and Altmetric Analysis of Retracted Articles on COVID-19

        Khan Hiba,Gupta Prakash,Zimba Olena,Gupta Latika 대한의학회 2022 Journal of Korean medical science Vol.37 No.6

        Background: With greater use of social media platforms for promotions of research articles, retracted articles tend to receive approximately the same attention. We systematically analyzed retracted articles from retractionwatch.com to look at the Altmetric Attention Scores (AAS) garnered over a period of time in order to highlight the role of social media and other platforms in advertising retracted articles and its effect on the spread of misinformation. Methods: Retractionwatch.com was searched for coronavirus disease 2019 related retracted papers on November 6th, 2021. Articles were excluded based on lack of digital object identifier (DOI), if they were preprint articles, absent AAS, and incomplete AAS of pre retraction, post retraction, or both scores. Results: A total of 196 articles were found on the Retraction Watch website of which 189 were retracted papers and 7 were expression of concern (EOC). We then identified 175 articles after excluding those that did not have a DOI and 30 preprint articles were also excluded giving 145 articles. Further exclusion of articles with absent AAS and incomplete AAS resulted in a total of 22 articles. Conclusion: Retracted articles receive significant online attention. Twitter and Mendeley were the most popular medium for publicizing retracted articles, therefore more focus should be given by journals and their Twitter accounts to discredit all their retracted articles. Preprints should be reconsidered as a whole by journals due to the huge risk they carry in disseminating false information.

      • KCI등재

        Service Users’ Confidence in Accessing Public Services in Nepal: What Makes Differences?

        Anil Kumar Gupta,Anup Bhurtel,Prakash C. Bhattarai 서울대학교행정대학원 2023 The Korean Journal of Policy Studies Vol.38 No.1

        This paper presents the factors associated with service users’ confidence in receiving public services in Nepal. The factors were taken from National Governance Survey 2017/ 18 (N=7334). The survey respondents were randomly selected from 43 of 77 districts of Nepal by using four-stage multiple cluster sampling from the service users who received public services in a year duration. The result showed that service users’ confidence in receiving public services differs by their locale, education level, caste/ethnicity, not having close contact (Afno Manchhe), and presence of intermediaries. Education, not having a person in close contact (Afno manchhe) and the presence of intermediaries have a negative effect, whereas locale (rural) and caste/ethnicity (Brahman/Chettri) have positive effects on service users’ confidence in accessing public services. Consideration of these factors boosts the confidence of the service users, which, in turn, promotes effective service delivery.

      • KCI등재

        The Cultural Context of Plagiarism and Research Misconduct in the Asian Region

        Rodrigues Flinta,Gupta Prakash,Khan Afzal Parvez,Chatterjee Tulika,Sandhu Nimrat Kaur,Gupta Latika 대한의학회 2023 Journal of Korean medical science Vol.38 No.12

        Plagiarism is one of the most frequent forms of research misconduct in South and East Asian countries. This narrative review examines the factors contributing to research misconduct, emphasizing plagiarism, particularly in South, East and Southeast Asian countries. We conducted a PubMed and Scopus search using the terms plagiarism, Asia, South Asia, East Asia, Southeast Asia, research misconduct and retractions in January of 2022. Articles with missing abstracts, incomplete information about plagiarism, publication dates before 2010, and those unrelated to South, East, and Southeast Asian countries were excluded. The retraction watch database was searched for articles retracted between 9th January 2020 to 9th January 2022. A total of 159 articles were identified, of which 21 were included in the study using the database search criteria mentioned above. The review of articles identified a lack of training in scientific writing and research ethics, publication pressure, permissive attitudes, and inadequate regulatory measures as the primary reasons behind research misconduct in scientific publications. Plagiarism remains a common cause of unethical publications and retractions in regions of Asia (namely South, East and Southeast). Researchers lack training in scientific writing, and substantial gaps exist in understanding various forms of plagiarism, which heavily contribute to the problem. There is an urgent need to foster high research ethics standards and adhere to journal policies. Providing appropriate training in scientific writing among researchers may help improve the knowledge of different types of plagiarism and promote the use of antiplagiarism software, leading to a substantial reduction in the problem.

      • SCOPUSKCI등재

        The current approach to the diagnosis of vascular anomalies of the head and neck: A pictorial essay

        Goel, Sinny,Gupta, Swati,Singh, Aarti,Prakash, Anjali,Ghosh, Sujoy,Narang, Poonam,Gupta, Sunita Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.2

        Throughout the years, various classifications have evolved for the diagnosis of vascular anomalies. However, it remains difficult to classify a number of such lesions. Because all hemangiomas were previously considered to involute, if a lesion with imaging and clinical characteristics of hemangioma does not involute, then there is no subclass in which to classify such a lesion, as reported in one of our cases. The recent classification proposed by the International Society for the Study of Vascular Anomalies (ISSVA, 2014) has solved this problem by including non-involuting and partially involuting hemangioma in the classification. We present here five cases of vascular anomalies and discuss their diagnosis in accordance with the ISSVA (2014) classification. A non-involuting lesion should not always be diagnosed as a vascular malformation. A non-involuting lesion can be either a hemangioma or a vascular malformation depending upon its clinicopathologic and imaging characteristics.

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