Synthesis of a New α-Dioxime Derivative and Its Application for Selective Homogeneous Liquid-Liquid Extraction of Cu(II) into a Microdroplet Followed by Direct GFAAS Determination

Ghiasvand, A. R.,Shadabi, S.,Kakanejadifard, A.,Khajehkoolaki, A. Korean Chemical Society 2005 Bulletin of the Korean Chemical Society Vol.26 No.5

A fast and reliable method for the selective separation and preconcentration of $Cu^{2+}$ ions using homogeneous liquid-liquid extraction was developed. A new $\alpha$-dioxime derivative (2H-1,4-benzothioazine-2,3(4H)dionedioxime, Dioxime I) was synthesized and investigated as a suitable selective complexing ligand for $Cu^{2+}$ ions. Zonyl FSA (FSA) was applied as a phase-separator agent under the slightly acidic pH conditions. Under the optimal experimental conditions ([FSA] = 3.2% w/v, [THF] = 19.5% v/v, [Dioxime I] = 1.9 ${\times}\;10^{-3}$ M, and pH = 4.7), 10 ${\mu}g\;of\;Cu^{2+}$ in 5.2 mL aqueous phase could be extracted quantitatively into 80 $\mu$L of the sedimented phase. The maximum concentration factor was 65-fold. The limit of detection of the proposed method was 0.005 ng $mL^{-1}$. The reproducibility of the proposed method, on the 10 replicate measurements, was 1.3%. The influence of the pH, type and volume of the water-miscible organic solvent, concentration of FSA, concentration of the complexing ligand and the effect of different diverse ions on the extraction and determination of $Cu^{2+}$ ions were investigated. The proposed method was applied to the extraction and determination of $Cu^{2+}$ ion in different synthetic and natural water samples.

Exploring the bioactive compounds from endophytic bacteria of a medicinal plant: Ephedra foliata (Ephedrales: Ephedraceae)

Mehrdad Ghiasvand,Ali Makhdoumi,Maryam M. Matin,Jamil Vaezi 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.1

To explore the role of endophytic bacteria from a medicinal plant in the production of bioactive compounds, bacterial strains (10 different taxa) were isolated from the surface sterilized stem of healthy Ephedra foliata. The endophytes were related to Firmicutes, Actinobacteria and Proteobacteria. They were identified as members of Bacillus (5 strains), Paenibacillus (2 strains), Brevundimonas (1 strain), Kytococcus (1 strain), and Microbacterium (1 strain). The bacterial metabolites were extracted by chloroform and examined for antimicrobial, antioxidant and anticancer properties. Strain F5 (Paenibacillus) showed moderate antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, and Escherichia coli. Its antibacterial activity was enhanced 2.3 times in the optimum conditions (starch 1% w/v, malt extract 0.2% w/v, pH 7, temperature 30 °C, inoculum size 3% v/v, and 48 h incubation time, at the basal tryptic soy broth medium). The highest DPPH scavenging capacity (EC50 at 43.0 µg/ml) was observed by the extract of the strain A1 (Microbacterium). The highest cytotoxic activity on HeLa cancerous cell was related to the extract obtain from strain A3 (Kytococcus) and its IC50 values were determined as (µg/ml) 104, 64, and 43 after 24, 48, and 72 h, respectively. Chemical identification of the extracts by tandem mass spectrometry revealed possible presence of alkaloid, aminoglycoside, flavonoid, and terpenoid compounds as previously extracted from other medicinal plants. Our results show the great potential of these endophytes for production of plant-related bioactive compounds.

Synthesis of a New α-Dioxime Derivative and Its Application for Selective Homogeneous Liquid-Liquid Extraction of Cu(II) into a Microdroplet Followed by Direct GFAAS Determination

A. R. Ghiasvand*,S. Shadabi,A. Kakanejadifard,A. Khajehkoolaki 대한화학회 2005 Bulletin of the Korean Chemical Society Vol.26 No.5

Theoretical definition of nurse–conscious mechanically ventilated patient communication: a scoping review with qualitative content analysis

Arezoo Mohamadkhani Ghiasvand,Meimanat Hosseini,Foroozan Atashzadeh-Shoorideh 대한중환자의학회 2023 Acute and Critical Care Vol.38 No.1

Providing critical nursing care for conscious mechanically ventilated patients is mediated via effective communication. This study aimed to identify and map the antecedents, attributes, consequences, and definition of nurse–conscious mechanically ventilated patient communication (N-CMVPC). This scoping review was conducted by searching the Cochrane Library and the CINAHL, Embase, PubMed, Web of Science, and Scopus databases, between 2001 and 2021. The keywords queried included "nurses," "mechanically ventilated patients," "mechanical ventilation," "intubated patients," "communication," "interaction," "relationships," "nurse–patient communication," "nurse–patient relations," "intensive care units," and "critical care." Studies related to communication with healthcare personnel or family members were excluded. The results indicated that N-CMVPC manifests as a set of attributes in communication experiences, emotions, methods, and behaviors of the nurse and the patient and is classified into three main themes, nurse communication, patient communication, and quantitative-qualitative aspects. N-CMVPC is a complex, multidimensional, and multi-factor concept. It is often nurse-controlled and can express itself as questions, sentences, or commands in the context of experiences, feelings, and positive or negative behaviors involving the nurse and the patient.

The Occurrence and Risk Assessment of Exposure to Aflatoxin M1 in Ultra-High Temperature and Pasteurized Milk in Hamadan Province of Iran

Amir Sasan Mozaffari Nejad,Ali Heshmati,Tayebe Ghiasvand 질병관리본부 2019 Osong Public Health and Research Persptectives Vol.10 No.4

Objectives: Aflatoxins are a category of poisonous compounds found in most plants, milk and dairy products. The present research was carried out to detect the presence of aflatoxin M1 (AFM1) in samples of milk collected from Hamadan province, Iran. Methods: Twenty five samples of ultra-high temperature (UHT) and 63 samples of pasteurized milk were collected and the amount of AFM1 was measured by an Enzyme-Linked Immunosorbent Assay method. In addition, the estimated daily intake (EDI) and hazard index (HI) of AFM1 was determined by the following equations:(EDI= mean concentration of AFM1 × daily consumption of milk/body weight; HI= EDI/Tolerance Daily Intake). Results: AFM1 was detected in 21 (84%) UHT milk samples and in 55 (87.30%) pasteurized milk samples. Seven (28%) samples of UHT and 21 (33.33%) pasteurized milk samples had higher AFM1 content than the limit allowed in the European Union and Iranian National Standard Limits (0.05 μg/kg). None of the samples exceeded the US Food and Drug Administration limit (0.5 μg/kg) for AFM1. EDI and HI for AM1 through milk were 0.107 ng/kg body weight/day, and 0.535, respectively. Conclusion: A significant percentage of milk produced by different factories in Iran (84% of UHT and 87.3% of pasteurized milk) was contaminated with AFM1. Therefore, more control and monitoring of livestock feeding in dairy companies may help reduce milk contamination with AFM1. As the HI value was lower than 1, it can be assumed that there was no risk of developing liver cancer due to milk consumption.

Misclassification Adjustment of Family History of Breast Cancer in a Case-Control Study: a Bayesian Approach

Moradzadeh, Rahmatollah,Mansournia, Mohammad Ali,Baghfalaki, Taban,Ghiasvand, Reza,Noori-Daloii, Mohammad Reza,Holakouie-Naieni, Kourosh Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

Background: Misreporting self-reported family history may lead to biased estimations. We used Bayesian methods to adjust for exposure misclassification. Materials and Methods: A hospital-based case-control study was used to identify breast cancer risk factors among Iranian women. Three models were jointly considered; an outcome, an exposure and a measurement model. All models were fitted using Bayesian methods, run to achieve convergence. Results: Bayesian analysis in the model without misclassification showed that the odds ratios for the relationship between breast cancer and a family history in different prior distributions were 2.98 (95% CRI: 2.41, 3.71), 2.57 (95% CRI: 1.95, 3.41) and 2.53 (95% CRI: 1.93, 3.31). In the misclassified model, adjusted odds ratios for misclassification in the different situations were 2.64 (95% CRI: 2.02, 3.47), 2.64 (95% CRI: 2.02, 3.46), 1.60 (95% CRI: 1.07, 2.38), 1.61 (95% CRI: 1.07, 2.40), 1.57 (95% CRI: 1.05, 2.35), 1.58 (95% CRI: 1.06, 2.34) and 1.57 (95% CRI: 1.06, 2.33). Conclusions: It was concluded that self-reported family history may be misclassified in different scenarios. Due to the lack of validation studies in Iran, more attention to this matter in future research is suggested, especially while obtaining results in accordance with sensitivity and specificity values.

An investigation on the mortars containing blended cement subjected to elevated temperatures using Artificial Neural Network (ANN) models

A.A. Ramezanianpour,M.E. Kamel,E. Ghiasvand,H. Shokrani,N. Bakhshi,A. Kazemian 사단법인 한국계산역학회 2012 Computers and Concrete, An International Journal Vol.10 No.6

This paper presents the results of an investigation on the compressive strength and weight loss of mortars containing three types of fillers as cement replacements; Limestone Filler (LF), Silica Fume (SF) and Trass (TR), subjected to elevated temperatures including 400oC, 600oC, 800oC and 1000oC. Results indicate that addition of TR to blended cements, compared to SF addition, leads to higher compressive strength and lower weight loss at elevated temperatures. In order to model the influence of the different parameters on the compressive strength and the weight loss of specimens, artificial neural networks (ANNs) were adopted. Different diagrams were plotted based on the predictions of the most accurate networks to study the effects of temperature, different fillers and cement content on the target properties. In addition to the impressive RMSE and R2 values of the best networks, the data used as the input for the prediction plots were chosen within the range of the data introduced to the networks in the training phase. Therefore, the prediction plots could be considered reliable to perform the parametric study.

Association between Healthy Eating Index-2010 and Fetuin-A Levels in Patients with Type 2 Diabetes: a Case-Control Study

( Farzad Roshanzamir ),( Maryam Miraghajani ),( Marjan Mansourian ),( Reza Ghiasvand ),( Seyyed Morteza Safavi ) 한국임상영양학회 2017 Clinical Nutrition Research Vol.6 No.4

The Healthy Eating Index-2010 (HEI-2010) assesses compliance with the 2010 Dietary Guidelines for Americans. Studies suggest that adherence to the HEI-2010 is related to lower the risk of type 2 diabetes (T2D). Fetuin-A, a novel biomarker for T2D, may play a linking role in the inverse association between HEI-2010 and T2D. Thus, a case-control analysis involving 107 patients with T2D and107 healthy subjects was conducted to determine the association between HEI-2010 and serum fetuin-A levels. The results of simple regression analysis showed that fetuin-A levels were positively associated with full name of body mass index (BMI) (p < 0.001), waist circumference (WC) (p < 0.001), fasting blood glucose (FBG) (p < 0.001), triglycerides (TG) (p = 0.003), gamma-glutamyl transferase (GGT) (p < 0.001), and homeostasis model assessment of insulin resistance (HOMA-IR) (p =0.001) and negatively associated with physical activity (PA) (p < 0.001), high-density lipoprotein (HDL) (p = 0.022), and HEI-2010 (p < 0.001) in all subjects. After controlling for confounders, the inverse association between fetuin-A and HEI-2010 remained significant in the subjects with T2D (β = -0.386; p < 0.001), 107 healthy controls (β = -0.237; p = 0.028), and all subjects (β = -0.298; p < 0.001). In conclusion, the present results suggested that higher quality diet assessed by HEI-2010 associates with lower serum fetuin-A levels in people with and without T2D. More studies are needed to confirm these findings.

Artificial neural network (ANN) approach for modeling of Cr(VI) adsorption from aqueous solution by zeolite prepared from raw fly ash (ZFA)

SeyedMostafa Hosseini Asl,Reza Katal,Maral Ahmadi,Mohamad Ghiasvand,Ali Tardast 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3

In this present work, artificial neural networks (ANN) are applied for prediction of percentage adsorption efficiency for the removal of Cr(VI) ions from aqueous solution by zeolite (ZFA) prepared from raw fly ash (RFA). The off operational parameters such as initial pH, adsorbent dosage, contact time and temperature is studied to optimize the conditions for maximum removal of Cr(VI) ions. Three equations, i.e. Morris–Weber, Lagergren, and pseudo second order have been tested to track the kinetics of removal process. The Langmuir, Freundlich, Redlich–Peterson, Temkin, and D-R are subjected to sorption data to estimate sorption capacity. Thermodynamic parameters showed that the adsorption of Cr(VI) onto ZFA was feasible, spontaneous and endothermic. Artificial neural networks are effective in modeling and simulation of highly non-liner multivariable relationships. The comparison of the removal efficiencies of Cr(VI) using ANN model and experimental results showed that ANN model can estimate the behavior of the Cr(VI) removal process under different conditions.

Presenting a New Detail for the Rigid Connection Between I-Shaped Beam and Concrete-Filled Steel Tube Column with Stiffened Channel Link

Mehrzad Tahamouli Roudsari,Shohreh Sohaei,Morteza Torkaman,Seyed Ali Safaee,Salar Tahmasebi,Saleh Mohammadi,Mohammad Mehdi Ghiasvand 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.2

Connections play an important role in the response of steel moment resisting frames to seismic loading. Prequalified rigid connections are applicable to I-shaped or box columns. In I-shape beam to concrete-filled tube (CFT) column connections, continuity and doubler plates cannot be added to the column. Various details have been proposed to address this issue, many of which are not constructionally convenient to implement. The aim of this study is to present a simple and suitable detailing for I-shape beam to concrete-filled tube column connections. To that end, six full-scale experimental samples were built and subjected to cyclic quasi-static loading. In the samples, stiffened and un-stiffened channel links were used to connect the beam to the column. In each sample, the stiffeners were installed on a different position on the channel link. The results showed that compared to the connection in which the beam is directly connected to the column, using the stiffened channel link with stiffeners along the beam’s flange increases the strength and ductility of the connection by 12% and 72%, respectively. Considering their desirable performance and easy implementation, these connections can be considered as a suitable detailing for I-shape beam to CFT column connections in seismic regions.