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      • KCI등재

        Experimental and modeling study of viscoelastic behaviors of magneto-rheological shear thickening fluids

        Gang Rou Peng,Weihua Li,Tongfei Tian,Jie Ding,Masami Nakano 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2

        Nowadays, both Magneto-rheological Fluid (MRF) and Shear Thickening Fluid (STF) have separatelyattracted considerable interest due to the fast reversible response to either external magnetic field or abruptshearing loading. In this paper, we fabricated a combined phase of Magneto-rheological Shear ThickeningFluid (MRSTF), where the 25 wt% STF is applied as medium phase with the addition of varied fractionsof iron particle. The investigation of the dynamic behavior of this novel material under oscillatory shear waslaunched in a parallel-plate rheometer. The relevance of the dynamic behavior to strain amplitude,frequency and external magnetic field were investigated and discussed. A four-parameter viscoelastic modelwas applied to reconstruct the mechanical behavior of the MRSTF under different working conditions, andthe parameters were identified within the Matlab optimization algorithm. The comparison between theexperimental data and the model prediction results indicated that the four-parameter model could predictviscoelastic material with desired accuracy. The MRSTF exhibits features of both components, while pronemore to MRF with the inception of external field excitations.

      • SCIESCOPUSKCI등재

        Experimental and modeling study of viscoelastic behaviors of magneto-rheological shear thickening fluids

        Peng, Gang Rou,Li, Weihua,Tian, Tong Fei,Ding, Jie,Nakano, Masami 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2

        Nowadays, both Magneto-rheological Fluid (MRF) and Shear Thickening Fluid (STF) have separately attracted considerable interest due to the fast reversible response to either external magnetic field or abrupt shearing loading. In this paper, we fabricated a combined phase of Magneto-rheological Shear Thickening Fluid (MRSTF), where the 25 wt% STF is applied as medium phase with the addition of varied fractions of iron particle. The investigation of the dynamic behavior of this novel material under oscillatory shear was launched in a parallel-plate rheometer. The relevance of the dynamic behavior to strain amplitude, frequency and external magnetic field were investigated and discussed. A four-parameter viscoelastic model was applied to reconstruct the mechanical behavior of the MRSTF under different working conditions, and the parameters were identified within the Matlab optimization algorithm. The comparison between the experimental data and the model prediction results indicated that the four-parameter model could predict viscoelastic material with desired accuracy. The MRSTF exhibits features of both components, while prone more to MRF with the inception of external field excitations.

      • KCI등재

        Evaluation of Anterior Ethmoidal Artery by 320-Slice CT Angiography with Comparison to Three-Dimensional Spin Digital Subtraction Angiography: Initial Experiences

        Juan Ding,Gang Sun,Yang Lu,Bing-bing Yu,Min Li,Li Li,Guo-ying Li,Zhao-hui Peng,Xu-Ping Zhang 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6

        Objective: To explore the usefulness of 320-slice CT angiography (CTA) for evaluating the course of the anterior ethmoidal artery (AEA) and its relationship with adjacent structures by using three-dimensional (3D) spin digital subtraction angiography (DSA) as standard reference. Materials and Methods: From December 2008 to December 2010, 32 patients with cerebrovascular disease, who underwent both cranial 3D spin DSA and 320-slice CTA within a 30 day period from each other, were retrospectively reviewed. AEA course in ethmoid was analyzed in DSA and CTA. In addition, adjacent bony landmarks (bony notch in medial orbital wall, anterior ethmoidal canal, and anterior ethmoidal sulcus) were evaluated with CTA using the MPR technique oriented along the axial, coronal and oblique coronal planes in all patients. The dose length product (DLP) for CTA and the dose-area product (DAP) for 3D spin DSA were recorded. Effective dose (ED) was calculated. Results: The entire course of the AEA was seen in all 32 cases (100%) with 3D spine DSA and in 29 of 32 cases (90.1%) with 320-slice CTA, with no significant difference (p = 0.24). In three cases where AEA was not visualized on 320-slice CTA, two were due to the dominant posterior ethmoidal artery, while the remaining case was due to diminutive AEA. On MPR images of 320-slice CT, a bony notch in the orbital medial walls was detected in all cases (100%, 64 of 64); anterior ethmoidal canal was seen in 28 of 64 cases (43.8%), and the anterior ethmoidal sulcus was seen in 63 of 64 cases (98.4%). The mean effective dose in CTA was 0.6 ± 0.25 mSv, which was significantly lower than for 3D spin DSA (1.3 ± 0.01 mSv) (p < 0.001). Conclusion: 320-slice CTA has a similar detection rate for AEA to that of 3D spin DSA; however, it is noninvasive, and may be preferentially used for the evaluation of AEA and its adjacent bony variations and pathologic changes in preoperative patients with paranasal sinus diseases. Objective: To explore the usefulness of 320-slice CT angiography (CTA) for evaluating the course of the anterior ethmoidal artery (AEA) and its relationship with adjacent structures by using three-dimensional (3D) spin digital subtraction angiography (DSA) as standard reference. Materials and Methods: From December 2008 to December 2010, 32 patients with cerebrovascular disease, who underwent both cranial 3D spin DSA and 320-slice CTA within a 30 day period from each other, were retrospectively reviewed. AEA course in ethmoid was analyzed in DSA and CTA. In addition, adjacent bony landmarks (bony notch in medial orbital wall, anterior ethmoidal canal, and anterior ethmoidal sulcus) were evaluated with CTA using the MPR technique oriented along the axial, coronal and oblique coronal planes in all patients. The dose length product (DLP) for CTA and the dose-area product (DAP) for 3D spin DSA were recorded. Effective dose (ED) was calculated. Results: The entire course of the AEA was seen in all 32 cases (100%) with 3D spine DSA and in 29 of 32 cases (90.1%) with 320-slice CTA, with no significant difference (p = 0.24). In three cases where AEA was not visualized on 320-slice CTA, two were due to the dominant posterior ethmoidal artery, while the remaining case was due to diminutive AEA. On MPR images of 320-slice CT, a bony notch in the orbital medial walls was detected in all cases (100%, 64 of 64); anterior ethmoidal canal was seen in 28 of 64 cases (43.8%), and the anterior ethmoidal sulcus was seen in 63 of 64 cases (98.4%). The mean effective dose in CTA was 0.6 ± 0.25 mSv, which was significantly lower than for 3D spin DSA (1.3 ± 0.01 mSv) (p < 0.001). Conclusion: 320-slice CTA has a similar detection rate for AEA to that of 3D spin DSA; however, it is noninvasive, and may be preferentially used for the evaluation of AEA and its adjacent bony variations and pathologic changes in preoperative patients with paranasal sinus diseases.

      • KCI등재

        Experimental study on heat transfer characteristics of supercritical carbon dioxide natural circulation

        Pengfei Wang,Peng Ding,Wenhuai Li,Rongshun Xie,Chengjie Duan,Gang Hong,Yaoli Zhang 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.3

        An experimental study has been conducted to investigate the heat transfer characteristics of supercriticalcarbon dioxide (sCO2) uniformly heated in the horizontal circular smooth tube. The results illustratedthat there was a significant difference in heat transfer between the top wall and bottom wall due to thebuoyancy. Bulk flow acceleration cannot be negligible in the high heat flux region, which leads to heattransfer deterioration. A new heat transfer correlation is proposed, in which the buoyancy parameter andbulk flow acceleration have been taken into account. The new correlation and six classic correlations forsCO2 are examined in horizontal tubes. The comparison indicates that the new correlation has a betterperformance for sCO2 flowing through a horizontal heating tube under natural circulation conditions. Forexample, 94.9% of the calculated results using the new heat transfer correlation were within ±30% of theexperimental results while only 87.9% of that using the Jackson correlation (the best of the six) werewithin the same error bands.

      • KCI등재

        Experimental and modelling study of the effect of temperature on shear thickening fluids

        Tongfei Tian,Gang Rou Peng,Weihua Li,Jie Ding,Masami Nakano 한국유변학회 2015 Korea-Australia rheology journal Vol.27 No.1

        This paper is a study of the effect that temperature has on a shear thickening fluid made from ethylene glycol and fumed silica, with 20%-26% weight fractions. Three typical temperatures, ranging from 20oC to 60oC, were selected to study the shear rate dependence of viscosity. The temperature tests showed that a high temperature increased the critical shear rate and lowered the shear thickening ratio. A viscosity function was proposed to represent the three characteristic regions in typical shear thickening fluid and to predict viscosity at different temperatures

      • KCI등재

        Fiber Ring Laser Intra-cavity Absorption Spectroscopy for Gas Sensing: Analysis and Experiment

        Mo Li,Kun Liu,Wencai Jing,Gang-Ding Peng 한국광학회 2010 Current Optics and Photonics Vol.14 No.1

        Fiber ring laser based intra-cavity absorption spectroscopic sensor has great potential for high sensitivity gas detection. Using the rate equations and propagation equations, we investigated theoretically factors that affect the sensitivity of such fiber ring laser sensors and determined the optimal design parameters and conditions for significant enhancement of the system sensitivity. Experiments have been conducted to determine the sensitivity enhancement performance. The results showed a factor of 25 ~ 30 in sensitivity enhancement in the experimental system, agreeing well with the theoretical expectations. Experiments on acetylene detection have also been carried out and the results showed that the ring cavity significantly increases the signal absorption and that high sensitivity can be obtained for gas detection.

      • KCI등재

        Associations of hypoxia inducible factor-1a gene polymorphisms with susceptibility to digestive tract cancers: a case–control study and meta-analysis

        Zhi-Hai Ni,Xian-Jun Liang,Jing-Gang Mo,Yi Zhang,Jian-Hua Liang,Yu-Sha Yang,Yong Zhou,Zhao-Hua Li,Jian-Liang Zhang,Yin-Lu Ding,Peng Zhang,Jin-Qing Wang 한국유전학회 2015 Genes & Genomics Vol.37 No.11

        We aim to investigate the correlations of hypoxia inducible factor-1a (HIF-1a) C1772T (rs11549465) and G1790A (rs11549467) gene polymorphisms with digestive tract cancers. A sum of 267 digestive tract cancers patients were hospitalized in Taizhou Central Hospital of Zhejiang Province as case group between December 2012 and December 2014. Additionally, 275 healthy people who had a physical examination in our hospital at the same time were selected as control group. Polymerase chain reaction-restriction fragment length polymorphism was utilized for detecting allele and genotype frequency of different locus in case and control group. Meta-analysis was performed using Comprehensive Metaanalysis 2.0 (Biostat Inc., Englewood, New Jersey, USA). Our result showed statistical significance only exists in family history of cancer between case and control group (P\0.05). Both C1772T (rs11549465) and G1790A (rs11549467) polymorphisms showed positive correlations with an increasing risk of digestive tract cancers. The frequencies of TT genotype of C1772T (rs11549465) and GA, AA genotypes of G1790A (rs11549467) polymorphisms in case group were evidently higher compared with the controls (all P\0.05). Besides, the comparison of allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) between two groups showed a significant difference (all P\0.05). Meta-analysis results further confirmed that the onset risk of digestive tract cancers may be improved under allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) (all P\0.05). Single nucleotide polymorphisms of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) may play a role in development of digestive tract cancers.

      • KCI등재

        Inhibitory Effect of Melanoma Differentiation Associated Gene-7/Interleukin-24 on Invasion In Vitro of Human Melanoma Cancer Cells

        Bi-wen Lin,Ze-long Jiao,Jian-feng Fan,Liang Peng,Lei Li,Zi-gang Zhao,Xiang-yu Ding,이형진 대한의학회 2013 Journal of Korean medical science Vol.28 No.6

        The acquisition of metastasis potential is a critical point for malignant tumors. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a potential tumor suppress gene and frequently down-regulated in malignant tumors. It has been implicated that overexpression of MDA-7 led to proliferation inhibition in many types of human tumor. Invasion is an important process which is potential to promote tumor metastasis. However, the role and potential molecular mechanism of mda-7/IL-24 to inhibit the invasion of human melanoma cancer is not fully clear. In this report, we identified a solid role for mda-7/IL-24 in invasion inhibition of human melanoma cancer LiBr cells, including decreasing of adhesion and invasion in vitro, blocking cell cycle, down-regulating the expression of ICAM-1, MMP-2/9, CDK1, the phosphorylation of ERK and Akt, NF-κB and AP-1 transcription activity. Meanwhile, there was an increased expression of PTEN in mda-7/IL-24 over-expression LiBr cells. Our results demonstrated that mda-7/IL-24 is a potential invasion suppress gene, which inhibits the invasion of LiBr cells by the down-regulation of ICAM-1, MMP-2/9, PTEN, and CDK1 expression. The molecular pathways involved were the MAPK/ERK, PI3K-Akt, NF-κB, and AP-1. These findings suggest that mda-7/IL-24 may be used as a possible therapeutic strategy for human melanoma cancer.

      • Microwave Ablation Treatment of Liver Cancer with a 2,450-MHz Cooled-shaft Antenna: Pilot Study on Safety and Efficacy

        Jiao, De-Chao,Zhou, Qi,Han, Xin-Wei,Wang, Ya-Feng,Wu, Gang,Ren, Jian-Zhuang,Wang, Yan-Li,Ding, Peng-Xu,Ma, Ji,Fu, Ming-Ti Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

        To evaluate efficacy of microwave ablation in a primary clinical study, sixty patients (44 men, 16 women; mean age 53 years) with 96, 1-8 cm (mean $3.20{\pm}0.17$ cm) liver cancers were treated with 2,450-MHz internally cooled-shaft antenna. Complete ablation (CA) and local tumor progression (LTP) rates as well as complications were determined. CA rates in small (< 3.0 cm), intermediate (3.1-5.0 cm) and large (5.1-8.0 cm) liver cancers were 96.4% (54/56), 92.3% (24/26) and 78.6% (11/14), respectively. During a mean follow-up period of $17.17{\pm}6.52$ months, LTP occurred in five (5.21%) treated cases. There was no significant difference in the CA and LTP rates between the HCC and liver metastasis patient subgroups (P<0.05). Microwave ablation provides a reliable, efficient, and safe technique to perform hepatic tumor ablation.

      • Prognostic Evaluation of Categorical Platelet-based Indices Using Clustering Methods Based on the Monte Carlo Comparison for Hepatocellular Carcinoma

        Guo, Pi,Shen, Shun-Li,Zhang, Qin,Zeng, Fang-Fang,Zhang, Wang-Jian,Hu, Xiao-Min,Zhang, Ding-Mei,Peng, Bao-Gang,Hao, Yuan-Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

        Objectives: To evaluate the performance of clustering methods used in the prognostic assessment of categorical clinical data for hepatocellular carcinoma (HCC) patients in China, and establish a predictable prognostic nomogram for clinical decisions. Materials and Methods: A total of 332 newly diagnosed HCC patients treated with hepatic resection during 2006-2009 were enrolled. Patients were regularly followed up at outpatient clinics. Clustering methods including the Average linkage, k-modes, fuzzy k-modes, PAM, CLARA, protocluster, and ROCK were compared by Monte Carlo simulation, and the optimal method was applied to investigate the clustering pattern of the indices including platelet count, platelet/lymphocyte ratio (PLR) and serum aspartate aminotransferase activity/platelet count ratio index (APRI). Then the clustering variable, age group, tumor size, number of tumor and vascular invasion were studied in a multivariable Cox regression model. A prognostic nomogram was constructed for clinical decisions. Results: The ROCK was best in both the overlapping and non-overlapping cases performed to assess the prognostic value of platelet-based indices. Patients with categorical platelet-based indices significantly split across two clusters, and those with high values, had a high risk of HCC recurrence (hazard ratio [HR] 1.42, 95% CI 1.09-1.86; p<0.01). Tumor size, number of tumor and blood vessel invasion were also associated with high risk of HCC recurrence (all p< 0.01). The nomogram well predicted HCC patient survival at 3 and 5 years. Conclusions: A cluster of platelet-based indices combined with other clinical covariates could be used for prognosis evaluation in HCC.

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