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      • KCI등재후보

        자동차용 Adjust Plate Progressive 금형 개발

        배용환,반갑수 한국산업안전학회 2002 한국안전학회지 Vol.17 No.4

        A automatic production system was developed for high productivity and safety. The semi-progressive die was unfavorable for more productivity, safety, material extravagance and incongruent high-speed production. Developed progressive die is suitable for the high production and guarantee triple production by acceptance of three array type for automobile adjust plate. We adopt Pro-Engineer^ⓕ for three dimensional computer aided design suitable for the disassembly and assembly evaluation. The conclusion of this study is as follow. First press die solid modeling system is built by using Pro-Engineer^ⓕ through this research and verified allowable tolerance and possibility of assembly and disassembly of parts. Therefore we can reduce die manufacturing time and cost. Second, We produce 1000 units per hot coil 1ton by traditional method, but we can acomplish material saving effect about effect about 12% as 1120 units in case of new progressive die. Fourth, we acomplished manufacturing cost curtailment effect more than 20% in comparison with traditional method.

      • KCI등재후보

        Transcriptional Properties of the BMP, TGF-β, RTK, Wnt, Hh, Notch, and JAK/STAT Signaling Molecules in Mouse Embryonic Stem Cells

        노정연,Gab-Yong Bae,채정일,유권,Deog-Bon Koo,Kyung-Kwang Lee,Yong-Mahn Han 사단법인 한국동물생명공학회 2006 Reproductive & developmental biology Vol.30 No.2

        Major characteristics of embryonic stem cells (ESCs) are sustaining of stemness and pluripotency by self-renewal. In this report, transcriptional profiles of the molecules in the developmentally important signaling pathways including Wnt, BMP4, TGF-β, RTK, Hh, Notch, and JAK/STAT signaling pathways were investigated to understand the self- renewal of mouse ESCs (mESCs), J1 line, and compared with the NIH3T3 cell line and mouse embryonic fibroblast (MEF) cells as controls. In the Wnt signaling pathway, the expression of Wnt3 was seen widely in mESCs, suggesting that the ligand may be an important regulator for self-renewal in mESCs. In the Hh signaling pathway, the expression of Gli and N-myc were observed extensively in mESCs, whereas the expression levels of in a Shh was low, suggesting that intracellular molecules may be essential for the self-renewal of mESCs. IGF-I, IGF-II, IGF-IR and IGF-IIR of RTK signaling showed a lower expression in mESCs, these molecules related to embryo development may be restrained in mESCs. The expression levels of the Delta and HES5 in Notch signaling were enriched in mESCs. The expression of the molecules related to BMP and JAK-STAT signaling pathways were similar or at a slightly lower level in mESCs compared to those in MEF and NIH3T3 cells. It is suggested that the observed differences in gene expression profiles among the signaling pathways may contribute to the self-renewal and differentiation of mESCs in a signaling-specific manner.

      • 캐핑머신 오실레이팅아암 기구부 설계

        배용환(Bae Yong-Hwan),반갑수(Ban Gab-Su) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.10

        The central research is development kinematic mechanism of oscillating ann for in-line capping machine. First, merits and shortcoming of existent capping machine is compared, informed technology is applied and supplemented shortcoming part maximum in this research. The disadvantage of existent capping machine is mechanical complex and expansive of price. Specially, it is very disadvantage in device efficiency side because existent device gives. Specially, importent part is very disadvantageous in device efficient side because existent device gives on cap adopting point contact form passing disk type of cap fastening device that stand in a line as a part do lid fastening chapter among these. This research developed shake style cap fastening device that have oscillating ann to supplement this shortcoming.

      • 플라즈마 EGR 조합시스템 디젤기관의 성능 및 배기 배출물 특성

        배명환(Myuang-whan Bae),하태용(Tae-yong Ha),김호갑(Ho-gab Kim),박재윤(Jae Yoon Park),하현진(Hyun JIN ha) 한국자동차공학회 2003 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

        The effects of non-thermal plasma reactor and recirculated exhaust gas on performance and exhaust emissions under four kinds of engine loads were experimentally investigated by using a four-cycle, four-cylinder, swirl chamber type, water-cooled diesel engine with a combined plasma EGR system operating at three kinds of engine speeds. The purpose of this study is to develop the combined exhaust gas recirculation(EGR) control system with a non-thermal plasma reacto for reducing NOⅹ and soot emissions simultaneously in diesel engines. The EGR system is used to reduce NOⅹ emissions, and the non-thermal plasma reactor is used to reduce soot emissions. The plasma system in this study is a flat-to-flat type reactor operated by a plasma power supply. The experiments arc performed at the fixed fuel injection timing of 4˚ ATDC regardless of experimenlal conditions. It is found that NOⅹ and soot emissions are decreased, especially soot emissions are markedly reduced at the middle loads, as the applied electrical voltage of plasma reactor is elevated.<br/>

      • Transcriptional Properties of the BMP, TGF-B, RTK, Wnt, Hh, Notch, and JAK/STAT Signaling Molecules in Mouse Embryonic Stem Cells

        Jeung-Yon Rho,Gab-Yong Bae,Jung-Il Chae,Kweon Yu,Deog-Bon Koo,Kyung-Kwang Lee,Yong-Mahn Han 한국동물생명공학회(구 한국동물번식학회) 2006 Reproductive & developmental biology Vol.30 No.2

        Major characteristics of embryonic stem cells (ESCs) are sustaining of stemness and pluripotency by self-renewal. In this report, transcriptional profiles of the molecules in the developmentally important signaling pathways including Wnt, BMP4, TGF-β, RTK, Hh, Notch, and JAK/STAT signaling pathways were investigated to understand the self- renewal of mouse ESCs (mESCs), J1 line, and compared with the NIH3T3 cell line and mouse embryonic fibroblast (MEF) cells as controls. In the Wnt signaling pathway, the expression of Wnt3 was seen widely in mESCs, suggesting that the ligand may be an important regulator for self-renewal in mESCs. In the Hh signaling pathway, the expression of Gli and N-myc were observed extensively in mESCs, whereas the expression levels of in a Shh was low, suggesting that intracellular molecules may be essential for the self-renewal of mESCs. IGF-I, IGF-II, IGF-IR and IGF-IIR of RTK signaling showed a lower expression in mESCs, these molecules related to embryo development may be restrained in mESCs. The expression levels of the Delta and HES5 in Notch signaling were enriched in mESCs. The expression of the molecules related to BMP and JAK-STAT signaling pathways were similar or at a slightly lower level in mESCs compared to those in MEF and NIH3T3 cells. It is suggested that the observed differences in gene expression profiles among the signaling pathways may contribute to the self-renewal and differentiation of mESCs in a signaling-specific manner.

      • Transcriptional Properties of the BMP, $TGF-\beta$, RTK, Wnt, Hh, Notch, and JAK/STAT Signaling Molecules in Mouse Embryonic Stem Cells

        Rho Jeung-Yon,Bae Gab-Yong,Chae Jung-Il,Yu Kweon,Koo Deog-Bon,Lee Kyung-Kwang,Han Yong-Mahn The Korean Society of Animal Reproduction 2006 Reproductive & developmental biology Vol.30 No.2

        Major characteristics of embryonic stem cells (ESCs) are sustaining of sternness and pluripotency by self-renewal. In this report, transcriptional profiles of the molecules in the developmentally important signaling pathways including Wnt, BMP4, $TGF-\beta$, RTK, Hh, Notch, and JAK/STAT signaling pathways were investigated to understand the self-renewal of mouse ESCs (mESCs), J1 line, and compared with the NIH3T3 cell line and mouse embryonic fibroblast (MEF) cells as controls. In the Wnt signaling pathway, the expression of Wnt3 was seen widely in mESCs, suggesting that the ligand may be an important regulator for self-renewal in mESCs. In the Hh signaling pathway, the expression of Gli and N-myc were observed extensively in mESCs, whereas the expression levels of in a Shh was low, suggesting that intracellular molecules may be essential for the self-renewal of mESCs. IGF-I, IGF-II, IGF-IR and IGF-IIR of RTK signaling showed a lower expression in mESCs, these molecules related to embryo development may be restrained in mESCs. The expression levels of the Delta and HESS in Notch signaling were enriched in mESCs. The expression of the molecules related to BMP and JAK-STAT signaling pathways were similar or at a slightly lower level in mESCs compared to those in MEF and NIH3T3 cells. It is suggested that the observed differences in gene expression profiles among the signaling pathways may contribute to the self-renewal and differentiation of mESCs in a signaling-specific manner.

      • KCI등재

        연노출근로자에 있어서 흡광광도법과 HPLC 법에 의한 요중δ - ALA 배설량과 연노출지표들 간의 관련성

        이병국,김용배,이성수,안규동,연유용,황보영,리갑수 한국산업위생학회 1996 한국산업보건학회지 Vol.6 No.1

        In order to compare the difference of the measurement of delta aminolevulinic acid(δ-ALA) in urine between HPLC method(HALA) and colorimetric method(CALA), and also to provide useful information for the new diagnostic criteria of δ-ALA in urine in lead poisoning, if at all possible in the future, authors studied 234 male lead workers who were selected from 7 storage battery factories, 3 secondary smelting industries, and 2 litharge making industries. Study subjects were selected on the basis of blood Zinc protoporphyrin(ZPP) level from low to high concentration to cover wide range of lead exposure. Study variables for this study were δ-ALA measured by two different methods, blood lead(PbB), and blood ZPP. The results were as follows: 1. There was very high correlation between δ-ALA measured by two method(r=0.989 : HALA = -0.8194+0.8110 × CALA), but the value of CALA was measured about 2㎎/L greater than HALA. 2. While the correlations of δ-ALA by two method with blood lead and blood ZPP were 0.46 and 0.37 respectively, they were increased to 0.63 and 0.57 if δ-ALA values were log-transformed. 3. Simple linear regression of δ-ALA measured by two method on ZPP were as follows : CALA = 2.0421 + 0.0341 × ZPP ( R² = 0.1385 p = 0.0001 ) HALA = 0.8006 + 0.0280 × ZPP ( R²= 0.1389 p = 0.0001 ) 4. Simple linear regression of δ-ALA measured by two method on PbB were as follows : CALA = -0.4134 + 0.1545 × PbB ( R² = 0.2085 p = 0.0001 ) HALA = -1.2893 + 0.1287 PbB ( R² = 0.2154 p = 0.0001 ) 5. Simple linear regression of log-transformed δ-ALA by two method on ZPP and PbB were as follows : logHALA = 0.3078 + 0.0060 ZPP ( R² = 0.3329 p = 0.0001 ) logCALA = 1.0189 + 0.0044 ZPP ( R² = 0.3290 p = 0.0001 ) logHALA = -0.0221 + 0.024b PbB ( R² = 0.4046 p = 0.0001 ) logCALA = 0.7662 + 0.0184 PbB ( R² = 0.4108 p = 0.0001 ) 6. The cumulative percent of colorimetric method to detect lead workers whose value of PbB and ZPP were over screening level such as 40 ㎍/㎗ and 100 ㎍/㎗ respectively was higher than HPLC method if cut-off level of δ-ALA for screening of lead poisoning was 5 ㎎/L. But if cut-off level of δ-ALA measured by HPLC was reduced to 3 ㎎/L which is compatible to 5 ㎎/L of δ-ALA measured by colorimetric method, there were good agreement between two methods and showed dose-response relationship with other lead exposure indices such as PbB and ZPP.

      • KCI등재

        정보공개청구를 통한 학술 정보 이용에 관한 연구 - Strauss와 Corbin의 근거이론적 접근 -

        윤은하,배삼열,심갑용,김용,Youn, Eunha,Bae, Sam-Yeol,Shim, Gab Yong,Kim, Yong 한국비블리아학회 2014 한국비블리아학회지 Vol.25 No.1

        본 연구는 정보공개법상에서 행해지는 학술 기록정보서비스의 문제점을 살펴보고, 이에 대한 개선사항을 제안하고자 하는 목적으로 수행되었다. 이를 위해 정보공개청구를 통해 공공기록을 이용한 경험이 있는 19명의 연구자와 심층 면접을 수행하였으며, 기록정보서비스가 학술연구 지원을 하는데 어떠한 문제가 있는지를 Strauss와 Corbin의 근거이론으로 분석했다. 1998년 정보공개법이 제정된 이후 일반인의 청구 건수는 지속적으로 증가하고 있는데 반해 학술연구자들의 이용률은 상당히 저조하다. 이러한 저조한 이용률은 정보공개 청구를 통한 학술정보 서비스 절차의 복잡성과 무관하지 않다. 본 연구는 학술이용자들의 기록정보서비스 이용행태를 분석하여 연구자들이 현행 정보공개청구절차에 상당히 불만족하고 있으며, 이는 학술 이용률 저하에 직접적인 원인이 되고 있다는 점을 밝혔다. The study aims to identify the procedural problems of the archival reference service through Freedom of Information Act. Since FOIA enacted in 1998, there has been a rapid increase of use of government information. However, most of academic users tend to be strongly dissatisfied with the user service. The authors argue that archival reference service through FOIA substantially prevents researchers from using archival records for their research and lower researcher's visits to archival institutions. For this, the study conducted 19 in-depth interviews of academic users and analyzed how FOIA influence academic user's information behaviors based on Strauss and Corbin's grounded theory.

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