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      • SCOPUSKCI등재

        The Influence of Channel Integration Quality on Omni-Channel Shopping Intention and Shopper Satisfaction in the E-commerce Industry in Indonesia

        Yosua Giovanni WIDJAJA(Yosua Giovanni WIDJAJA ),Idris Gautama SO(Idris Gautama SO ),Rini SETIOWATI(Rini SETIOWATI ),Asnan FURINTO(Asnan FURINTO ) 한국유통과학회 2022 유통과학연구 Vol.20 No.12

        Purpose: The purpose of this study was to determine the effect of utilitarian value, hedonic value, channel integration quality on Omni- Channel Shopping Intention and shopper satisfaction in the e-commerce industry in Indonesia. Research design, data and methodology: This research method uses quantitative research methods with purposive sampling technique. The hypothesis was tested using SEM-PLS. Results: Based on the results of the analysis and discussion, it can be concluded that there is an influence between the Utilitarian value on the Omni-channel shopping intention, there is no effect between the hedonic value on the Omni-channel shopping intention, there is no influence between the quality of Channel integration on the Omni-channel shopping intention, there is an influence between the quality of Channel integration and the Omni-channel shopping intention between utilitarian values on shopper satisfaction, there is no effect between hedonic values on shopper satisfaction, there is an influence between channel integration quality on shopper satisfaction, and there is an influence between Omni-channel shopping intentions on shopper satisfaction. Conclusions: The findings of this study prove that Omni-Channel Shopping Intention is one of the most effective management and marketing techniques to enhance an important aspect of their company, namely an efficient and holistic consumer shopping experience.

      • KCI등재

        The Mixmaster Model as a Cosmological Framework and Aspects of its Quantum Dynamics

        Giovanni Imponente,Giovanni Montani 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.III

        This paper provides a review of some recent issues on the Mixmaster dynamics concerning the features of its stochasticity. After a description of the geometrical structure characterizing the homogeneous cosmological models in the Bianchi classification and the Belinsky-Khalatnikov-Lifshitz piecewise representation of the types VIII and IX oscillatory regime, we face the question regarding the time covariance of the resulting chaos as viewed in terms of continuous Misner-Chitr\'e like variables. Finally, we show how in the statistical mechanics framework the Mixmaster chaos raises as semiclassical limit of the quantum dynamics in the Planckian era.

      • KCI등재

        Use of the ultrasound-based total malignancy score in the management of thyroid nodules

        Giovanni Guido Pompili,Silvia Tresoldi,Anna Ravell,Alessandra Primolevo,Giovanni Di Leo,Gianpaolo Carrafiello 대한초음파의학회 2018 ULTRASONOGRAPHY Vol.37 No.4

        Purpose: The purpose of this study was to validate the role of the total malignancy score (TMS)in identifying thyroid nodules suspicious for malignancy through the sum of their ultrasoundfeatures. Methods: The local ethical committee approved this prospective observational study. Weexamined 231 nodules in 231 consecutive patients (164 females and 67 males; age range, 20 to87 years; median age, 59 years; interquartile range, 48 to 70 years) who underwent ultrasoundfollowed by fine-needle aspiration cytology (FNAC). The nodules were further classified usingthe TMS, which considers ultrasound features (number, echogenicity, structure, halo, margins,Doppler signal, calcifications, and growth), and the Bethesda System for Reporting ThyroidCytopathology (TBSRTC), which considers cytological features. Patients with non-negativenodules (TBSRTC categories III to VI) underwent histological analysis, repeated FNAC, or 2years of regular ultrasound follow-up. The associations between the final diagnosis, each of theultrasound features, and the TMS were estimated using the chi-square test, the Mann-WhitneyU test, and multivariate logistic regression. A receiver operating characteristic (ROC) curve wasused to evaluate the diagnostic accuracy of the TMS. Results: On ultrasound, 47% of the nodules (108 of 231) had a TMS <3, 18% (42 of 231) hada TMS of 3, and 35% (81 of 231) had a TMS >3. The FNAC results of 85% of the nodules (196of 231) were benign, while 15% (35 of 231) had non-negative results. Hypoechogenicity, solidstructure, the presence of microcalcifications, and the number of nodules were independentpredictors of the final diagnosis, and the diagnostic accuracy of the TMS was good (area underthe ROC curve, 0.82). Conclusion: The TMS system is simple to use, reliable, easily reproducible, and closely reflectsmalignancy risk. Based on our results, FNAC could be limited to nodules with a TMS ≥3 withoutmissing any cases of carcinoma.

      • KCI등재

        The Immune System in Irritable Bowel Syndrome

        ( Giovanni Barbara ),( Cesare Cremon ),( Giovanni Carini ),( Lara Bellacosa ),( Lisa Zecchi ),( Roberto De Giorgio ),( Roberto Corinaldesi ),( Vincenzo Stanghellini ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2011 Journal of Neurogastroenterology and Motility (JNM Vol.17 No.4

        The potential relevance of systemic and gastrointestinal immune activation in the pathophysiology and symptom generation in the irritable bowel syndrome (IBS) is supported by a number of observations. Infectious gastroenteritis is the strongest risk factor for the development of IBS and increased rates of IBS-like symptoms have been detected in patients with inflammatory bowel disease in remission or in celiac disease patients on a gluten free diet. The number of T cells and mast cells in the small and large intestine of patients with IBS is increased in a large proportion of patients with IBS over healthy controls. Mediators released by immune cells and likely from other non-immune competent cells impact on the function of enteric and sensory afferent nerves as well as on epithelial tight junctions controlling mucosal barrier of recipient animals, isolated human gut tissues or cell culture systems. Antibodies against microbiota antigens (bacterial flagellin), and increased levels of cytokines have been detected systemically in the peripheral blood advocating the existence of abnormal host-microbial interactions and systemic immune responses. Nonetheless, there is wide overlap of data obtained in healthy controls; in addition, the subsets of patients showing immune activation have yet to be clearly identified. Gender, age, geographic differences, genetic predisposition, diet and differences in the intestinal microbiota likely play a role and further research has to be done to clarify their relevance as potential mechanisms in the described immune system dysregulation. Immune activation has stimulated interest for the potential identification of biomarkers useful for clinical and research purposes and the development of novel therapeutic approaches. (J Neurogastroenterol Motil 2011;17:349-359)

      • SCOPUSKCI등재

        On the Trade Balance Response to Monetary Shocks: the Marshall-Lerner Conditions Reconsidered

        ( Giovanni Lombardo ) 세종대학교 경제통합연구소 (구 세종대학교 국제경제연구소) 2001 Journal of Economic Integration Vol.16 No.4

        This paper studies the applicability of the Marshall-Lerner condition to the “basic” Obstfeld and Rogoff (1995) model. It shows that the Marshall-Lerner condition does apply to this class of models with homothetic preferences when product differentiation across countries is imposed. This paper also shows that, in certain cases, the intertemporal substitution and the dynamic income effect can make the mere elasticity of substitution an insufficient indicator of the response of the current account to monetary shocks.

      • Software Vulnerability Design and Approaches for Securing SCADA Control Systems

        Giovanni A. Cagalaban,Jae-gu Song,Sungmo Jung,Seok soo Kim 보안공학연구지원센터 2009 International Journal of Smart Home Vol.3 No.1

        Despite growing awareness of security issues especially in SCADA networks, there exist little or scarce information about SCADA vulnerabilities and attacks. Where security has been a consideration, there has been no clear methodology to assess the security impacts brought about by attacks. Worst, there have been no or very little security tools that have been released publicly. This research aims to addresses the issues regarding security and vulnerability testing. Software program was created to simulate the vulnerability testing and carry out assessment methodologies to test existing SCADA software design and implementation. This paper also describes the application of a well know security testing approach known as the software implemented fault injection as well as building the model for security vulnerabilities identification and analysis. Impact analysis was also performed to provide a better understanding of the attacks. Sufficient security measures are needed to block all possible intrusion points into the SCADA system to significantly reduce the chances of a successful attack.

      • KCI등재

        Benzisothiazoles and β-Adrenoceptors: Synthesis and Pharmacological Investigation of Novel Propanolamine and Oxypropanolamine Derivatives in Isolated Rat Tissues

        Giovanni Morini,Enzo Poli,Mara Comini,Alessandro Menozzi,Cristina Pozzoli 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.12

        In an attempt to examine the ability of benzisothiazole-based drugs to interact with β-adrenoceptors, a series of 1,2-benzisothiazole derivatives, which were substituted with various propanolamine or oxypropanolamine side chains in the 2 or 3 position, were synthesised and tested. The pharmacological activity of these compounds at the β-adrenoceptors was examined using isolated rat atria and small intestinal segments, which preferentially express the β1- and β3-adrenoceptor-mediated responses, respectively. None of these products showed any β- adrenoceptor agonistic activity. In contrast, the 2- and 3-substituted isopropyl, tert-butyl, benzyl, and piperonyl derivatives 2a-d and 3a-d elicited surmountable inhibition of the isoprenaline- induced chronotropic effects in the atria, suggesting competitive antagonism at the β1- recognition site. The pA2 values revealed tert-butyl 3b and the isopropyl substituted piperonyl derivatives 3a to be the most effective. Remarkably, many of the 2-substituted propanolamines were less active than the corresponding 3-substituted oxypropanolamines. With the exception of compound 3b, none of these drugs antagonised the muscle relaxant activity of isoprenaline in the intestine, suggesting no effect on the β3- adrenoceptors. These results confirm the ability of the benzisothiazole ring to interact with the β-adrenoceptors, and demonstrate that 2-substitution with propanolamine or 3-substitution with oxypropanolamine groups yields compounds with preferential antagonistic activity at the cardiac β1-adrenoceptors. The degree of antagonism depends strongly on both the nature of the substituent and its position on the benzisothiazole ring.

      • KCI등재

        Testosterone Replacement Therapy and Cardiovascular Risk: A Review

        Giovanni Corona G,Giulia Rastrelli,Elisa Maseroli,Alessandra Sforza,Mario Maggi 대한남성과학회 2015 The World Journal of Men's Health Vol.33 No.3

        Recent reports in the scientific and lay press have suggested that testosterone (T) replacement therapy (TRT) is likely to increase cardiovascular (CV) risk. In a final report released in 2015, the Food and Drug Administration (FDA) cautioned that prescribing T products is approved only for men who have low T levels due to primary or secondary hypogonadism resulting from problems within the testis, pituitary, or hypothalamus (e.g., genetic problems or damage from surgery, chemotherapy, or infection). In this report, the FDA emphasized that the benefits and safety of T medications have not been established for the treatment of low T levels due to aging, even if a man’s symptoms seem to be related to low T. In this paper, we reviewed the available evidence on the association between TRT and CV risk. In particular, data from randomized controlled studies and information derived from observational and pharmacoepidemiological investigations were scrutinized. The data meta-analyzed here do not support any causal role between TRT and adverse CV events. This is especially true when hypogonadism is properly diagnosed and replacement therapy is correctly performed. Elevated hematocrit represents the most common adverse event related to TRT. Hence, it is important to monitor hematocrit at regular intervals in T-treated subjects in order to avoid potentially serious adverse events.

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