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( Eunmi Gil ),( Choon Hyuck D. Kwon ),( Jong Man Kim ),( Gyu-seong Choi ),( Jin Seok Heo ),( Wontae Cho ),( Seung Hwan Lee ),( Jin Yong Choi ),( Mi Sook Gwak ),( Geum-youn Gwak ),( Jae-won Joh ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
Aims: Although laparoscopic liver resection has developed rapidly, its usefulness for the treatment of large tumors is less clear, due to concerns about compromising oncological principles and patient safety. The purpose of this study was to explore the feasibility and safety of laparoscopic liver resection for the treatment of hepatocellular carcinoma (HCC) with a tumor size larger than 5 cm. Methods: From January 2007 to December 2014, we performed laparoscopic liver resection in 45 patients with HCC with a tumor size ≥ 5 cm. Perioperative outcome, tumor recurrence and overall patient survival were analyzed. Results: Median age was 60 years old (IQR 52-68) and 64.4% (29/45) was male. Seven patients (15.6%) had larger than 10cm of HCC. No operative deaths occurred and six of the laparoscopic procedures were converted to open resection (conversion rate 13.3%). Median operation time was 365 minutes (IQR 277-443) and median estimated blood loss (EBL) was 400.0 ml (IQR 275-600). There was no R1 or R2 resection and median resection margin was 19.0 mm (IQR 8.0-33.0). Complications above Clavien-Dindo classification grade III occurred in four patients (8.9%). The median overall follow-up time was 10.7 month (range 1.1-62.1). 1-year recurrence free survival (RFS) and overall survival (OS) were 86.0% and 95.5%, and 3-year RFS and OS were 70.7% and 86.0%. Conclusions: Laparoscopic liver resection seems safe and feasible in patients with HCC with a tumor size larger than 5 cm. Expansion of indication for laparoscopic liver resection in patients with HCC may be considered.
Cho, Eunmi,Kim, Sung Hyun,Kim, Mac,Park, Jin-Seong,Lee, Sang-Jin Elsevier 2019 Surface & coatings technology Vol.370 No.-
<P><B>Abstract</B></P> <P>Ag-plasma polymer fluorocarbon (PPFC) nanocomposite thin films were fabricated using ternary carbon nanotube-Ag-polytetrafluoroethylene composite target by the mid-range frequency dual sputtering method. Ag nanoparticles of diameter 6–8 nm were found to be uniformly distributed in the PPFC matrix. The Ag-PPFC nanocomposite thin films coated on a polyethylene terephthalate (PET) substrate showed higher visible light transmittance than the bare substrate owing to the low refractive index of the thin film and the optical compensation effect; the coating also exhibited excellent water repellency due to the low surface energy of the PPFC matrix. The Ag nanoparticles had no observable effect on the optical and surface properties of the thin film. The Ag-PPFC nanocomposite thin films on fabric substrates exhibited deposition coverage on both front and back surfaces of the fabric, thereby rendering super-hydrophobic characteristics to the entire substrate. The Ag-PPFC nanocomposite thin films were found to have superior antimicrobial properties, suppressing the growth and proliferation of bacteria by up 92.2% compared with uncoated substrates. This is attributed to the super-hydrophobic property of the PPFC matrix and the antimicrobial characteristics of Ag nanoparticles.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ag-plasma polymer fluorocarbon(PPFC) nanocomposite thin film fabricated using CNT-Ag-PTFE target by sputtering process </LI> <LI> PPFC matrix and Ag nanoparticles have grown independently without chemical reaction </LI> <LI> Super-hydrophobic surface are realized by coating Ag-PPFC nanocomposite on fiber substrate </LI> <LI> Antimicrobial properties of Ag-PPFC nanocomposite are superior due to the activity of Ag and water repellency of PPFC </LI> </UL> </P>
Jin Ah Cho,Eunmi Park 한국영양학회 2015 Nutrition Research and Practice Vol.9 No.2
BACKGROUND/OBJECTIVES: Curcumin, a major component of the Curcuma species, contains antioxidant and anti-inflammatory properties. Although it was found to induce apoptosis in cancer cells, the functional role of curcumin as well as its molecular mechanism in anti-inflammatory response, particularly in intestinal cells, has been less investigated. The intestine epithelial barrier is the first barrier and the most important location for the substrate coming from the lumen of the gut. SUBJECTS/METHODS: We administered curcumin treatment in the human intestinal epithelial cell lines, T84 and Caco-2. We examined endoplasmic reticulum (ER) stress response by thapsigargin, qPCR of XBP1 and BiP, electrophysiology by wild-type cholera toxin in the cells. RESULTS: In this study, we showed that curcumin treatment reduces ER stress and thereby decreases inflammatory response in human intestinal epithelial cells. In addition, curcumin confers protection without damaging the membrane tight junction or actin skeleton change in intestine epithelial cells. Therefore, curcumin treatment protects the gut from bacterial invasion via reduction of ER stress and anti-inflammatory response in intestinal epithelial cells. CONCLUSIONS: Taken together, our data demonstrate the important role of curcumin in protecting the intestine by modulating ER stress and inflammatory response post intoxication.
Changes in Perception of Cultural Diversity in COVID-19 Era
Jin Bae Sul,Eunmi Lee 위기관리 이론과 실천 2021 Crisisonomy Vol.17 No.9
This study investigates changes in the public perception of cultural diversity and significant factors in this change. We analyzed the raw data collected for the 2021 Public Perception Survey on the Future of Korea, conducted by KAPA and found a change in public perceptions of the importance of cultural diversity relative to 2014. A difference was seen according to age and ideological orientation, such that cultural diversity was considered more important with increasing age and more progressive orientation. Finally, personal trust had a positive effect on the importance of cultural diversity and multicultural orientation. Further, trust in government had a positive effect on multicultural orientation, and people with higher trust in government did not think lack cultural diversity. Discussion and future research directions are presented based on the major findings of the study.