Single and two implant-supported overdentures: A comparison of objective prognostic parameters and QOL

Niharika Yadav(Niharika Yadav ),Deeksha Arya(Deeksha Arya ),Saumyendra Vikram Singh(Saumyendra Vikram Singh ),Kamleshwar Singh(Kamleshwar Singh ),Mayank Singh(Mayank Singh ),Divya Mehrotra(Divya Mehro 대한치과이식임플란트학회 2022 The Korean Academy of Implant Dentistry Vol.41 No.3

Purpose: This study compared a) crestal bone loss, b) implant stability quotient (ISQ), c) probing depth, d) denture fracture incidence, and e) posterior residual ridge resorption (RRR) of two implant and single implant-supported overdentures and assessed the quality of life (QOL) was evaluated before and after giving the prosthesis. Materials and Methods: The study was a randomized longitudinal cohort study. Eighty subjects were selected for the study and divided randomly into two groups (n=40): Group 2IOD— two implant-supported overdentures; Group 1IOD— Single implant-supported overdentures. Except for the number of implants, the common surgical, implant, and the prosthetic protocol was followed for the two groups. An oral health impact profile EDENT questionnaire was completed by the patients before giving the implant-supported overdenture and after one year of prosthesis delivery to evaluate the effects of oral health on the quality of life. Probing pocket depth (mm), ISQ (resonance frequency analysis), denture fracture incidence, posterior RRR (mm), and crestal bone loss (mm) were assessed and compared at the baseline and one year after implant placement (early loading protocol) for the two groups. Standard statistical tests, including an unpaired t-test with SPSS software, were used for the analysis. Results: The average crestal bone loss in group 2IOD was insignificantly lower than group 1IOD. The ISQ values were higher for group 2IOD than group 1IOD at one year. The ISQ values for both groups at 12 months were similar (P>0.05). The probing depth at both time intervals yielded insignificant intergroup differences. No denture fracture was reported in either group. At 12 months, posterior ridge resorption in group 2IOD was 0.33±0.08, which was significantly lower than in group 1IOD. Conclusions: A one implant-supported overdenture is a comparable treatment option with two implant-supported overdentures for edentulous patients, having the advantages of lower cost and less surgical trauma. However, there may be more posterior RRR with this treatment modality.

Path-Connectivity of Two-Interval MSF Wavelets

Singh, Divya Department of Mathematics 2011 Kyungpook mathematical journal Vol.51 No.3

In this paper, we obtain that the space $\mathcal{W}_2$ of minimally supported frequency wavelets, the supports of whose Fourier transforms consist of two intervals, is path-connected.

Melanization plasticity of Drosophila kikkawai, Drosophila leontia and reciprocal hybrids under different temperatures

Singh Divya,Ramniwas Seema,Tyagi Pankaj Kumar,Kumar Girish,Gola Deepak 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.1

Drosophila (Sophophora) kikkawai, Burla, 1954 and Drosophila (Sophophora) leontia, Tsacas & David 1978 are closely related sibling species, the former being cosmopolitan and the latter is restricted to tropical localities. We investigated the influence of introgressive hybridization on phenotypic diversity of the two sibling species in the present study. How hybridization supports the relative abundance of pure species according to latitudinal cline is the aim of this study because hybrids show a tendency to acquire geographical location of their parent species in equal or greater abundance. How hybridization supports the plasticity for melanization of hybrids is not explored yet. The two species can cross and generate hybrids. For this, we crossed true breeding strains of both species to obtain the hybrids i.e. dark female (♀) of D. kikkawai (D. k) with males (♂) of D. leontia (D. l) in cross I and light ♀ of D. k with ♂ of D. l in cross II along with their reciprocal crosses. Finally, we studied the plasticity of both species and their hybrids at 6 growth temperatures (14, 17, 21, 25, 28 and 31 ◦ C). We found that there is no plasticity for melanization in true breeding darker and lighter strain of D. kikkawai as well as D. leontia whereas hybrids of both species showed high phenotypic plasticity. Significant differences in slope values across tem peratures in parental and hybrid lines suggest plastic effects. Phenotypic variation in abdominal melanization in hybrids can be interpreted as a result of gene introgression with D. kikkawai. We conclude that introgressive hybridization might be an important, although underestimated, mechanism shaping species distribution and adaptation.

Accelerated hypofractionated breast radiotherapy with simultaneous integrated boost: a feasibility study

Budhi Singh Yadav,Shipra Gupta,Divya Dahiya,Ankita Gupta,Arun Singh Oinam 대한방사선종양학회 2022 Radiation Oncology Journal Vol.40 No.2

Purpose: To assess the feasibility of accelerated hypofractionated radiotherapy with simultaneous integrated boost (SIB) in patients with breast cancer. Materials and Methods: A total of 27 patients after breast-conserving surgery were included in this study. Patients were planned on a four-dimensional computerized tomogram, and contouring was done using RTOG guidelines. The dose was 34 Gy/10#/2 week to the breast and 40 Gy/10#/2 week to the tumor bed as SIB with volumetric modulated arc technique. The primary endpoint was grade 2 acute skin toxicity. Doses to the organs-at-risk were calculated. Toxicities and cosmesis were assessed using RTOG/LENT/SOMA and HARVARD/NSABP/RTOG grading scales, respectively. Disease-free survival (DFS) and overall survival (OS) were calculated with Kaplan-Meier curves. Results: The mean age of the patients was 42 years. Left and right breast cancers were seen in 17 (63%) and 10 (37%) patients, respectively. The mean values of ipsilateral lung V₁₆ and contralateral lung V₅ were 16.01% and 3.74%, respectively. The mean heart doses from the left and right breast were 7.25 Gy and 4.37 Gy, respectively. The mean doses to the contralateral breast, oesophagus, and Dmax to brachial plexus were 2.64 Gy, 3.69 Gy, and 26.95 Gy, respectively. The mean value of thyroid V₂₅ was 19.69%. Grade 1 and 2 acute skin toxicities were observed in 9 (33%) and 5 (18.5%) patients, respectively. Grade 2 hyperpigmentation, edema, and induration were observed in 1 (3.7%), 2 (7.4%), and 4 (14.8%) patients, respectively. Mild breast pain and arm/shoulder discomfort were reported by 1 (3.4%) patient. The median follow-up was 51 months (range, 12 to 61 months). At four years, breast induration, edema, and fibrosis were observed in 1 (3.7%) patient. Cosmesis was excellent and good in 21 (78%) and 6 (22%) patients, respectively. Local recurrence and distant metastases occurred in 1 (3.7%) and 2 (7.4%) patients, respectively. DFS and OS at four years were 88% and 92%, respectively. Conclusion: With this radiotherapy schedule, acute and late toxicity rates were acceptable with no adverse cosmesis. Local control, DFS, and OS were good.

Molecular fossils “pseudogenes” as functional signature in biological system

Rajesh Kumar Singh,Divya Singh,Arpana Yadava,Akhileshwar Kumar Srivastava 한국유전학회 2020 Genes & Genomics Vol.42 No.6

Pseudogenes have been known as non-functional molecular relics developed from inactivated genomic mutations while evolution. However, they have a various function at distinct molecular stages (DNA, RNA and protein) in different biological events including in cancer and associated with parental-gene-dependently and parental-gene independently. The interactions of pseudogenes with ancestor genes or other genes alter in their sequences and transcriptional processes. Pseudogene of RNA sequences have multiple functions in post-transcriptional activities as antisense RNAs, endogenous small-interference RNAs, and competing endogenous RNAs. Moreover, it also plays vital roles in controlling of its parent genes and other pseudogenes transcribing into RNA. Pseudogene transcripts make small interfering RNA or decline cellular miRNA level. The current review focuses on pseudogene functional signature in human genome by regulating the gene expression.

Synthesis, Thermal Studies and Spectral Characterization of Co(II), Ni(II), Cu(II), and Zn(II) Complexes with Some Polymeric Diacetyl Acyldihydrazone Ligands

Vinod Prasad Singh,Divya Pratap Singh 한국고분자학회 2013 Macromolecular Research Vol.21 No.7

Two polymeric ligands, diacetyl oxaloyldihydrazone (DODH), diacetyl malonoylhydrazone (DMDH)and their Co(II), Ni(II), Cu(II) and Zn(II) complexes were synthesized and characterized by elemental analyses, IR,mass, 1H & 13C NMR, ESR and electronic spectral studies. The ligands and their complexes are highly insoluble in water and common organic solvents and decompose at high temperature. The metal atoms are embedded between two polymeric chains of the organic ligands and the monomeric unit of the polymeric chain behaves as a neutral bidentate ligand and coordinate through two >C=N groups to different metals as indicated by 1H & 13C NMR and IR spectral studies. The molecular weights determined by 1H NMR and mass spectral studies suggest oligomeric nature of the ligands and their Zn(II) complexes. The magnetic susceptibility measurements and electronic spectral studies indicate a square planar geometry around the metal ion in Co(II) and Ni(II) complexes. Electronic and ESR spectral studies for Cu(II) complexes suggest a distorted octahedral stereochemistry around the metal atom and 2B1g as the ground state. Thermal studies (TGA and DTA) of some of the complexes in inert atmosphere show a multi-step exothermic decomposition of the bonded organic ligand at high temperature and metal (II) chloride as the end product.

Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocyclic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach

Mishra, Priya,Singh, Sarita,Ankit, Preyas,Fatma, Shahin,Singh, Divya,Singh, Jagdamba Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.4

Herein is reported a simple and efficient synthesis of isoflavones starting from various substituted phenacyl bromides and salicylaldehydes in presence of NHC. The mechanism involved domino catalysis type approach with consumption and regeneration of catalyst in two catalytic cycles. This method proved to be very lucrative and gives very good yield. The method described here represents an environmentally benign alternative to classical approach.

Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocyclic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach

Priya Mishra,Sarita Singh,Preyas Ankit,Shahin Fatma,Divya Singh,Jagdamba Singh 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.4

Herein is reported a simple and efficient synthesis of isoflavones starting from various substituted phenacyl bromides and salicylaldehydes in presence of NHC. The mechanism involved domino catalysis type approach with consumption and regeneration of catalyst in two catalytic cycles. This method proved to be very lucrative and gives very good yield. The method described here represents an environmentally benign alternative to classical approach.

A Comparative Analysis of Adaptive IIR Filtering Techniques using LabVIEW

Divya Sharma,Rashpinder Kaur,Gurjinder Singh 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.8

Removal of noises from real-time speech signal is a typical problem. The signal interference initiated by background noise is a major problem in voice communication systems. Adaptive Filtering methods have emerged as an important technology for communication systems. This technique has been employed to improve the quality of the speech signal by cancelling the undesirable phenomenon such as acoustic noise. In this paper, for the removal of additional noise from speech signal an adaptive filter has been designed using LMS, NLMS, SLMS and VSS-LMS algorithms. This paper presents the instigation of Least Mean Square algorithm (LMS), Normalized Least Mean Square algorithm (NLMS), Sign Least mean square algorithm (SLMS) and Variable step size (VSS) algorithm on an infinite impulse response (IIR) filter using adaptive filter toolkit of LabVIEW software. User interface is designed using LabVIEW to obtain the learning curves for these adaptive algorithms. The final results show the comparison of the performance of the entire proposed algorithms with each other. The complete performance of the designed system in terms of stability and convergence rate has been observed.

Instituting environmental sustainability and climate resilience into the governance process: Exploring the potential of new urban development schemes in India

Divya Sharma,Seema Singh 한국외국어대학교 국제지역연구센터 2016 International Area Studies Review Vol.19 No.1

India is on the cusp of major transformation in terms of how it translates and directs urbanization. The recently announced flagship schemes of the Government of India – the ‘Smart Cities’ scheme, the Atal Mission for Rejuvenation and Urban Transformation (AMRUT) scheme, The Housing for All scheme – offer avenues for addressing some of the most daunting challenges that cities in India face today, including climate change impacts and disaster risks. While India has faced multiple climate-related hazards in the recent years, the frequency and intensity of extreme events on the Indian subcontinent has arguably begun to increase. While there have been clear entry points in the governance system and policy making through which the climate resilience agenda could have been integrated into urban development planning in Indian cities, it has not yet been done, largely due to the lack of realization of this very need among India’s decision makers. This paper discusses these issues in detail and outlines the gaps and challenges for bringing climate resilience into the mainstream agenda. Furthermore, it explores the possible avenues or entry points for integrating climate resilience into the urban development agenda through these schemes.