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      • Nonprofits Use Social Media in Alabama : A Case Study of Social Media for Youth Volunteerism and Program Management

        H. Daniel Xu,Alycia Jeong 인하대학교 글로벌e거버넌스연구소 2015 International Journal of Policy and Governance Net Vol.3 No.1

        Many nonprofits know they must use social media to engage in, and im-prove, stakeholder relations. However, knowing social media is valuable and using it in a beneficial and appropriate manner are two distinct matters. How can a nonprofit with very limited funding, scope, and human re-sources effectively utilize social media to strengthen public engagement and maintain mission alignment? By examining existing research and iden-tifying the key ways nonprofits are using social media, this study develops an understanding of the most impactful use of time, energy, and resources. The concepts and hypotheses culled from the review of relevant theoretical framework and past research are fleshed out in the real experiences of YouthServe, a Birmingham, Alabama nonprofit organization that creates and connects local youth to volunteer opportunities. YouthServe’s success in using various social media, to promote volunteerism and facilitate event planning, can guide other nonprofit organizations evaluating and striving to advance their own social media footprint.

      • Biweekly gemcitabine-paclitaxel, gemcitabine-carboplatin, or gemcitabine-cisplatin as first-line treatment in metastatic breast cancer after anthracycline failure: a phase II randomized selection trial.

        Xu, Binghe,Jiang, Zefei,Kim, Sung-Bae,Yu, Shiying,Feng, Jifeng,Malzyner, Artur,Del Giglio, Auro,Chung, Hyun C,Shen, Li Jun,Pen, Daniel Lee Kay Maruzen Co 2011 Breast cancer Vol.18 No.3

        <P>The primary objective of this multicenter, open-label, randomized, parallel, phase II selection trial was to compare the objective tumor response to biweekly (every 2 weeks) gemcitabine/paclitaxel, gemcitabine/carboplatin, and gemcitabine/cisplatin as first-line treatment for metastatic breast cancer.</P>

      • Dynamic Microcontainers as Microvacuums for Collecting Nanomaterials After Clinical Treatments

        Choi, Daniel S.,Park, Jungrae,Ke Xu,Kringel, Rose,Choi, John J.,Jeon, In Tak,Young Keun Kim IEEE 2013 IEEE transactions on magnetics Vol.49 No.7

        <P>We present a feasible method to collect ferromagnetic nanomaterials(FNMs) after clinical utilization by employing ferromagnetic microcontainers (MCs). The cubic MCs with dimensions of 200 micrometers have gold-coated nickel frames and were tethered such a way that they are able to remove FNMs from cells with the use of an external magnetic field. The study has been conducted in two parts: 1) enhancement of the motion of MCs in glass-based microfluidic channels filled with viscous fluids by magnetically-driven spinning MCs, i.e., “dynamic MCs”; 2)sweeping FNMs from the cells using magnetic attractive forces between FNMs and MCs through a “microvacuum”process. Our study shows that spinning MCs can transport better than nonspinning MCs through viscous fluids. We found that approximately 70% of FNMs internalized with human embryonic cells (HEK-293) were removed from the cells by the spinning MCs. Such in-vitro experiments suggest the possibility of resolving the issue of removing FNMs used for clinical treatments from human body after treatments.</P>

      • KCI등재

        Distributed Totally Decomposed Cumulative Goppa Coded-Cooperative Communication with Optimized Selection in the Relay

        Waweru, Daniel Kariuki,Yang, Fengfan,Zhao, Chunli,Paul, Lawrence Muthama,Xu, Hongjun 한국통신학회 2023 Journal of communications and networks Vol.25 No.2

        In this paper, powerful induced-cyclic totally decom-posed cumulative Goppa (TDCG) codes are selected and used forcoded-cooperative diversity, which can fit wireless communicationapplications. Two TDCG codes employed at the source andrelay nodes establish the joint design of the destination channelcode. In the cooperation phase, we consider an optimized relaychannel code which improves the overall bit-error-rate (BER)performance. Two methods of optimization are explored. Themost practical method for optimization in terms of reducedprocessing complexity is proposed. We use a joint decodingwhich exploits all the resources gained by the cooperation schemeat the destination. The BER performance is evaluated throughMonte-Carlo simulations with BPSK modulation and coherentdetection over the flat Rayleigh fading channel. The proposedTDCG coded-cooperative diversity scheme exhibit a better BERperformance than the non-cooperation scheme and other existingcoded cooperation methods of similar code rates under similarchannel conditions.

      • Multi-terminal transport measurements of MoS2 using a van der Waals heterostructure device platform.

        Cui, Xu,Lee, Gwan-Hyoung,Kim, Young Duck,Arefe, Ghidewon,Huang, Pinshane Y,Lee, Chul-Ho,Chenet, Daniel A,Zhang, Xian,Wang, Lei,Ye, Fan,Pizzocchero, Filippo,Jessen, Bjarke S,Watanabe, Kenji,Taniguchi, Nature Pub. Group 2015 Nature nanotechnology Vol.10 No.6

        <P>Atomically thin two-dimensional semiconductors such as MoS2 hold great promise for electrical, optical and mechanical devices and display novel physical phenomena. However, the electron mobility of mono- and few-layer MoS2 has so far been substantially below theoretically predicted limits, which has hampered efforts to observe its intrinsic quantum transport behaviours. Potential sources of disorder and scattering include defects such as sulphur vacancies in the MoS2 itself as well as extrinsic sources such as charged impurities and remote optical phonons from oxide dielectrics. To reduce extrinsic scattering, we have developed here a van der Waals heterostructure device platform where MoS2 layers are fully encapsulated within hexagonal boron nitride and electrically contacted in a multi-terminal geometry using gate-tunable graphene electrodes. Magneto-transport measurements show dramatic improvements in performance, including a record-high Hall mobility reaching 34,000???cm(2)???V(-1)???s(-1) for six-layer MoS2 at low temperature, confirming that low-temperature performance in previous studies was limited by extrinsic interfacial impurities rather than bulk defects in the MoS2. We also observed Shubnikov-de Haas oscillations in high-mobility monolayer and few-layer MoS2. Modelling of potential scattering sources and quantum lifetime analysis indicate that a combination of short-range and long-range interfacial scattering limits the low-temperature mobility of MoS2.</P>

      • Use of ion pairing reagents for sensitive detection and separation of phospholipids in the positive ion mode LC-ESI-MS

        Dodbiba, Edra,Xu, Chengdong,Payagala, Tharanga,Wanigasekara, Eranda,Moon, Myeong Hee,Armstrong, Daniel W. Royal Society of Chemistry 2011 The Analyst Vol.136 No.8

        <P>Phospholipids make up one of the more important classes of biological molecules. Because of their amphipathic nature and their charge state (<I>e.g.</I>, negatively charged or zwitterionic) detection of trace levels of these compounds can be problematic. Electrospray ionization mass spectrometry (ESI-MS) is used in this study to detect very small amounts of these analytes by using the positive ion mode and pairing them with fifteen different cationic ion pairing reagents. The phospholipids used in this analysis were phosphatidylethanolamine (PE), phosphatidylcholine (PC), phosphatidylglycerol (PG), phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidic acid (PA), 1,2-diheptanoyl-<I>sn</I>-<I>glycero</I>-3-phosphocholine (DHPC), cardiolipin (CA) and sphingosyl phosphoethanolamine (SPE). The analysis of these molecules was carried out in the single ion monitoring (SIM) positive mode. In addition to their detection, a high performance liquid chromatography and mass spectrometry (HPLC-MS) method was developed in which the phospholipids were separated and detected simultaneously within a very short period of time. Separation of phospholipids was developed in the reverse phase mode and in the hydrophilic interaction liquid chromatography (HILIC) mode HPLC. Their differences and impact on the sensitivity of the analytes are compared and discussed further in the paper. With this technique, limits of detection (LODs) were very easily recorded at low ppt (ng L<SUP>−1</SUP>) levels with many of the cationic ion pairing reagents used in this study.</P> <P>Graphic Abstract</P><P>This process shows the complex formation of the phospholipids and the cationic ion pairing reagents, while being electrosprayed and detected in the positive ion mode ESI-MS. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0an00848f'> </P>

      • Numerical form-finding of multi-order tensegrity structures by grouping elements

        Xinyu Wang,Jianguo Cai,Daniel Sang-hoon Lee,Yixiang Xu,Jian Feng 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.41 No.2

        Multi-order tensegrity structures are an attractive form of compliant deployable structures. An efficient numerical form-finding method is proposed for multi-stable tensegrity structures in this paper. The current method first analyze the force density matrix for sets of more feasible force densities that satisfy the non-degeneracy conditions. Then, based on symmetrical grouping of elements, a genetic algorithm is used to minimize the eigenvalues; as a result, multiple orders of equilibrium can be found. For the investigation, two symmetric tensegrity structures are analyzed using the currently proposed method, and the method’s applicability and accuracy have been examined.

      • SCOPUSKCI등재

        Review and Evaluation of Hand-Arm Coordinate Systems for Measuring Vibration Exposure, Biodynamic Responses, and Hand Forces

        Dong, Ren G.,Sinsel, Erik W.,Welcome, Daniel E.,Warren, Christopher,Xu, Xueyan S.,McDowell, Thomas W.,Wu, John Z. Occupational Safety and Health Research Institute 2015 Safety and health at work Vol.6 No.3

        The hand coordinate systems for measuring vibration exposures and biodynamic responses have been standardized, but they are not actually used in many studies. This contradicts the purpose of the standardization. The objectives of this study were to identify the major sources of this problem, and to help define or identify better coordinate systems for the standardization. This study systematically reviewed the principles and definition methods, and evaluated typical hand coordinate systems. This study confirms that, as accelerometers remain the major technology for vibration measurement, it is reasonable to standardize two types of coordinate systems: a tool-based basicentric (BC) system and an anatomically based biodynamic (BD) system. However, these coordinate systems are not well defined in the current standard. Definition of the standard BC system is confusing, and it can be interpreted differently; as a result, it has been inconsistently applied in various standards and studies. The standard hand BD system is defined using the orientation of the third metacarpal bone. It is neither convenient nor defined based on important biological or biodynamic features. This explains why it is rarely used in practice. To resolve these inconsistencies and deficiencies, we proposed a revised method for defining the realistic handle BC system and an alternative method for defining the hand BD system. A fingertip-based BD system for measuring the principal grip force is also proposed based on an important feature of the grip force confirmed in this study.

      • KCI등재

        A novel CHD7 mutation in an adolescent presenting with growth and pubertal delay

        Maria-Christina Antoniou,Thérèse Bouthors,Cheng Xu,Franziska Phan-Hug,Eglantine Elowe-Gruau,Sophie Stoppa-Vaucher,Almer van der Sloot,James Acierno,Daniele Cassatella,Celine Richard,Andrew Dwyer,Nelly 대한소아내분비학회 2019 Annals of Pediatirc Endocrinology & Metabolism Vol.24 No.1

        Mutations in the CHD7 gene, encoding for the chromodomain helicase DNAbinding protein 7, are found in approximately 60% of individuals with CHARGE syndrome (coloboma, heart defects, choanal atresia, retarded growth and development, genital hypoplasia, ear abnormalities and/or hearing loss). Herein, we present a clinical case of a 14-year-old male presenting for evaluation of poor growth and pubertal delay highlighting the diagnostic challenges of CHARGE syndrome. The patient was born full term and underwent surgery at 5 days of life for bilateral choanal atresia. Developmental milestones were normally achieved. At age 14 his height and weight were -2.04 and -1.74 standard deviation score respectively. He had anosmia as well as prepubertal testes and micropenis (4 cm×1 cm). The biological profile showed low basal serum testosterone and gonadotropins (testosterone, 0.2 nmol/L; luteinizing hormone, 0.5 U/L; follicle-stimulating hormone, 1.3 U/L), and otherwise normal pituitary function and normal imaging of the hypothalamic-pituitary area. The constellation of choanal atresia, anosmia, mild dysmorphic features, micropenis and delayed puberty were suggestive of CHARGE syndrome. Targeted genetic testing of CHD7 was performed revealing a de novo heterozygous CHD7 mutation (c.4234T>G [p.Tyr1412Asp]). Further paraclinical investigations confirmed CHARGE syndrome. Despite the presence of suggestive features, CHARGE syndrome remained undiagnosed in this patient until adolescence. Genetic testing helps clarify the phenotypic and genotypic spectrum to facilitate diagnosis, thus promoting optimal follow-up, treatment, and appropriate genetic counselling.

      • SCISCIESCOPUS

        Stability of heavy metals in soil washing residue with and without biochar addition under accelerated ageing

        Shen, Zhengtao,Hou, Deyi,Zhao, Bin,Xu, Wendi,Ok, Yong Sik,Bolan, Nanthi S.,Alessi, Daniel S. Elsevier 2018 Science of the Total Environment Vol.619 No.-

        <P><B>Abstract</B></P> <P>Soil washing residue (SWR), which typically concentrates the washed toxic metals and is comprised of high contents of clay particles, may pose risks to the surrounding environment. This study aims to simulate accelerated ageing to assess the stability of selected metals (Cd<SUP>2+</SUP> (132mg/kg), Cu<SUP>2+</SUP> (248mg/kg) and Pb<SUP>2+</SUP> (3470mg/kg)) in a SWR (89.68% of clay) with and without biochar treatment. The soil was incubated under constant moisture and wet-dry cycles (accelerated ageing), respectively, and the mobility and fractions of heavy metals in the soils with and without biochar treatment were examined. Under the constant moisture condition, biochar addition at 5% w/w reduced the leached Cd<SUP>2+</SUP> (by 1.81%) and Cu<SUP>2+</SUP> (by 8.70%) from SWR at day 1 and the leached Cu<SUP>2+</SUP> (by 51.08%) and Pb<SUP>2+</SUP> (by 25.36%) from SWR at day 14; however, the leached metals in the TCLP solution from the biochar-amended soils still exceed the regulatory limits (1mg/L for Cd<SUP>2+</SUP>, 5mg/L for Pb<SUP>2+</SUP>, no regulatory limits for Cu<SUP>2+</SUP>). Conversely, accelerated ageing (14days) significantly increased the fractions of exchangeable Cd<SUP>2+</SUP> (from 3.63–3.94% to 6.21–6.29%) and Pb<SUP>2+</SUP> (from 0.025–0.027% to 0.034–0.041%) as well as the TCLP leachabilities of Cd<SUP>2+</SUP> (from 2.91–3.28% to 3.46–3.73%), Cu<SUP>2+</SUP> (from 0.08–0.10% to 0.03–0.06%) and Pb<SUP>2+</SUP> (from 0.25–0.35% to 0.52–0.57%) in the soils, as compared with those incubated under constant moisture, regardless of biochar addition. This study reveals challenges associated with stabilising SWR due to the presence of residual fine-grained particles.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cd<SUP>2+</SUP> and Pb<SUP>2+</SUP> in soil washing residue (SWR) exceeds TCLP regulation limit. </LI> <LI> Heavy metal mobility in SWR was reduced by biochar addition. </LI> <LI> Accelerated ageing mobilised heavy metals in SWR regardless of biochar addition. </LI> <LI> Accelerated ageing show SWR poses long-term risks to the environment. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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